Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:7-ketocholesterol
go back to main search page
Accession:CHEBI:64294 term browser browse the term
Definition:A cholestanoid that consists of cholesterol bearing an oxo substituent at position 7.
Synonyms:related_synonym: (3-beta)-3-Hydroxycholest-5-en-7-one;   (3S,8S,9S,10R,13R,14S,17R)-3-hydroxy-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-1,2,3,4,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-7-one;   3-beta-Hydroxycholest-5-en-7-one;   3beta-hydroxycholest-5-en-7-one;   7-oxocholesterol;   Formula=C27H44O2;   InChI=1S/C27H44O2/c1-17(2)7-6-8-18(3)21-9-10-22-25-23(12-14-27(21,22)5)26(4)13-11-20(28)15-19(26)16-24(25)29/h16-18,20-23,25,28H,6-15H2,1-5H3/t18-,20+,21-,22+,23+,25+,26+,27-/m1/s1;   InChIKey=YIKKMWSQVKJCOP-ABXCMAEBSA-N;   SMILES=[H][C@@]1(CC[C@@]2([H])[C@]3([H])C(=O)C=C4C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)CCCC(C)C
 xref: Beilstein:2169084 "ChemIDplus";   CAS:566-28-9 "ChemIDplus"
 xref_mesh: MESH:C003001
 xref: PMID:17846428 "Europe PMC";   PMID:18469840 "Europe PMC";   PMID:18495460 "Europe PMC";   PMID:18603819 "Europe PMC";   PMID:18936140 "Europe PMC";   PMID:19351882 "Europe PMC";   PMID:19429117 "Europe PMC";   PMID:19464253 "Europe PMC";   PMID:19834037 "Europe PMC";   PMID:19880645 "Europe PMC";   PMID:20424663 "Europe PMC";   PMID:20463934 "Europe PMC";   PMID:20466046 "Europe PMC";   PMID:20471966 "Europe PMC";   PMID:20554621 "Europe PMC";   PMID:20698354 "Europe PMC";   PMID:21035514 "Europe PMC";   Reaxys:2169084 "Reaxys"


show annotations for term's descendants       view all columns           Sort by:
 
7-ketocholesterol term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcg5 ATP binding cassette subfamily G member 5 JBrowse link 17 84,658,174 84,683,011 RGD:6480464
G Abcg8 ATP binding cassette subfamily G member 8 JBrowse link 17 84,676,302 84,700,341 RGD:6480464
G Acat1 acetyl-Coenzyme A acetyltransferase 1 JBrowse link 9 53,580,522 53,610,350 RGD:6480464
G Ahr aryl-hydrocarbon receptor JBrowse link 12 35,497,979 35,534,989 RGD:6480464
G Akt1 thymoma viral proto-oncogene 1 JBrowse link 12 112,653,821 112,674,796 RGD:6480464
G Bax BCL2-associated X protein JBrowse link 7 45,461,695 45,468,205 RGD:6480464
G Bcl2 B cell leukemia/lymphoma 2 JBrowse link 1 106,538,176 106,714,290 RGD:6480464
G Bcl2l11 BCL2-like 11 (apoptosis facilitator) JBrowse link 2 128,126,038 128,162,547 RGD:6480464
G Bid BH3 interacting domain death agonist JBrowse link 6 120,893,119 120,917,141 RGD:6480464
G Casp1 caspase 1 JBrowse link 9 5,298,517 5,307,281 RGD:6480464
G Casp3 caspase 3 JBrowse link 8 46,617,291 46,639,698 RGD:6480464
G Casp7 caspase 7 JBrowse link 19 56,396,634 56,442,348 RGD:6480464
G Casp8 caspase 8 JBrowse link 1 58,795,228 58,847,503 RGD:6480464
G Casp9 caspase 9 JBrowse link 4 141,793,612 141,815,978 RGD:6480464
G Ccl2 chemokine (C-C motif) ligand 2 JBrowse link 11 82,035,577 82,037,452 RGD:6480464
G Ccl3 chemokine (C-C motif) ligand 3 JBrowse link 11 83,647,843 83,649,378 RGD:6480464
G Ccl4 chemokine (C-C motif) ligand 4 JBrowse link 11 83,648,624 83,664,683 RGD:6480464
G Ccl5 chemokine (C-C motif) ligand 5 JBrowse link 11 83,525,778 83,530,518 RGD:6480464
G Cd38 CD38 antigen JBrowse link 5 43,868,809 43,912,374 RGD:6480464
G Csf2 colony stimulating factor 2 (granulocyte-macrophage) JBrowse link 11 54,247,270 54,249,899 RGD:6480464
G Csf3 colony stimulating factor 3 (granulocyte) JBrowse link 11 98,700,897 98,704,503 RGD:6480464
G Cxcl10 chemokine (C-X-C motif) ligand 10 JBrowse link 5 92,346,638 92,348,889 RGD:6480464
G Cxcl15 chemokine (C-X-C motif) ligand 15 JBrowse link 5 90,794,534 90,803,067 RGD:6480464
G Cybb cytochrome b-245, beta polypeptide JBrowse link X 9,435,252 9,487,766 RGD:6480464
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 JBrowse link 9 57,687,928 57,703,824 RGD:6480464
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 JBrowse link 1 74,713,146 74,737,897 RGD:6480464
G Cyp7a1 cytochrome P450, family 7, subfamily a, polypeptide 1 JBrowse link 4 6,264,113 6,275,631 RGD:6480464
G Egfr epidermal growth factor receptor JBrowse link 11 16,752,203 16,913,907 RGD:6480464
G Hmgcr 3-hydroxy-3-methylglutaryl-Coenzyme A reductase JBrowse link 13 96,648,962 96,670,936 RGD:6480464
G Icam1 intercellular adhesion molecule 1 JBrowse link 9 21,015,960 21,028,797 RGD:6480464
G Il10 interleukin 10 JBrowse link 1 131,019,845 131,024,970 RGD:6480464
G Il1b interleukin 1 beta JBrowse link 2 129,363,842 129,371,170 RGD:6480464
G Il1rn interleukin 1 receptor antagonist JBrowse link 2 24,336,860 24,351,491 RGD:6480464
G Il6 interleukin 6 JBrowse link 5 30,013,114 30,019,975 RGD:6480464
G Kng2 kininogen 2 JBrowse link 16 22,985,852 23,029,101 RGD:6480464
G Map1lc3b microtubule-associated protein 1 light chain 3 beta JBrowse link 8 121,590,468 121,598,047 RGD:6480464
G Mapk1 mitogen-activated protein kinase 1 JBrowse link 16 16,983,379 17,047,453 RGD:6480464
G Mapk3 mitogen-activated protein kinase 3 JBrowse link 7 126,759,626 126,765,816 RGD:6480464
G Mmp2 matrix metallopeptidase 2 JBrowse link 8 92,827,291 92,853,421 RGD:6480464
G Mmp9 matrix metallopeptidase 9 JBrowse link 2 164,940,744 164,955,850 RGD:6480464
G Mtor mechanistic target of rapamycin kinase JBrowse link 4 148,448,582 148,557,685 RGD:6480464
G Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 JBrowse link 3 135,584,655 135,691,982 RGD:6480464
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha JBrowse link 12 55,489,409 55,492,647 RGD:6480464
G Nlrp3 NLR family, pyrin domain containing 3 JBrowse link 11 59,541,569 59,566,956 RGD:6480464
G Nos2 nitric oxide synthase 2, inducible JBrowse link 11 78,920,787 78,960,232 RGD:6480464
G Npc1l1 NPC1 like intracellular cholesterol transporter 1 JBrowse link 11 6,211,011 6,230,245 RGD:6480464
G Parp1 poly (ADP-ribose) polymerase family, member 1 JBrowse link 1 180,568,975 180,601,254 RGD:6480464
G Pon1 paraoxonase 1 JBrowse link 6 5,168,090 5,193,987 RGD:6480464
G Pon2 paraoxonase 2 JBrowse link 6 5,264,620 5,298,373 RGD:6480464
G Pon3 paraoxonase 3 JBrowse link 6 5,220,852 5,256,242 RGD:6480464
G Ptk2b PTK2 protein tyrosine kinase 2 beta JBrowse link 14 66,153,257 66,281,068 RGD:6480464
G Pycard PYD and CARD domain containing JBrowse link 7 127,991,373 127,993,867 RGD:6480464
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) JBrowse link 19 5,637,440 5,648,131 RGD:6480464
G Smpd1 sphingomyelin phosphodiesterase 1, acid lysosomal JBrowse link 7 105,554,360 105,558,389 RGD:6480464
G Tgm2 transglutaminase 2, C polypeptide JBrowse link 2 158,116,405 158,146,392 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 17 35,199,367 35,202,007 RGD:6480464
G Trp53 transformation related protein 53 JBrowse link 11 69,580,359 69,591,873 RGD:6480464
G Vcam1 vascular cell adhesion molecule 1 JBrowse link 3 116,110,020 116,129,688 RGD:6480464
G Vegfa vascular endothelial growth factor A JBrowse link 17 46,016,993 46,032,377 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20734
    role 20712
      application 20105
        pharmaceutical 19809
          drug 19809
            protective agent 16117
              neuroprotective agent 15134
                7-ketocholesterol 59
Path 2
Term Annotations click to browse term
  CHEBI ontology 20734
    subatomic particle 20727
      composite particle 20727
        hadron 20727
          baryon 20727
            nucleon 20727
              atomic nucleus 20727
                atom 20727
                  main group element atom 20650
                    p-block element atom 20650
                      carbon group element atom 20386
                        carbon atom 20362
                          organic molecular entity 20362
                            organic molecule 20208
                              organic cyclic compound 19904
                                organic polycyclic compound 16796
                                  steroid 12765
                                    hydroxy steroid 12296
                                      3-hydroxy steroid 10175
                                        3beta-hydroxy steroid 2086
                                          3beta-hydroxy-Delta(5)-steroid 1947
                                            cholesterol 328
                                              7-ketocholesterol 59
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.