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Term:alpha-cyano-4-hydroxycinnamic acid
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Accession:CHEBI:64340 term browser browse the term
Definition:A monohydroxycinnamic acid that is 4-hydroxycinnamic acid in which the hydrogen alpha- to the carboxy group is replaced by a cyano group. It is used as a matrix in matrix-assisted laser desorption/ionization (MALDI) mass spectrometry for the analysis of peptides and oligonucleotides.
Synonyms:exact_synonym: (2E)-2-cyano-3-(4-hydroxyphenyl)prop-2-enoic acid
 related_synonym: 2-cyano-3-(4-hydroxyphenyl)acrylic acid;   CHCA;   Formula=C10H7NO3;   InChI=1S/C10H7NO3/c11-6-8(10(13)14)5-7-1-3-9(12)4-2-7/h1-5,12H,(H,13,14)/b8-5+;   InChIKey=AFVLVVWMAFSXCK-VMPITWQZSA-N;   SMILES=OC(=O)C(\\C#N)=C\\c1ccc(O)cc1;   alpha-Cyano
 xref: CAS:28166-41-8 "ChemIDplus"
 xref_mesh: MESH:C007175
 xref: PMID:11217742 "Europe PMC";   PMID:14715888 "Europe PMC";   PMID:15144210 "Europe PMC";   PMID:15150841 "Europe PMC";   PMID:15694775 "Europe PMC";   PMID:16401911 "Europe PMC";   PMID:19435303 "Europe PMC";   PMID:19927305 "Europe PMC";   PMID:8750232 "Europe PMC";   Reaxys:2645333 "Reaxys";   Wikipedia:Alpha-cyano-4-hydroxycinnamic_acid

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alpha-cyano-4-hydroxycinnamic acid term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Agt angiotensinogen JBrowse link 19 57,321,594 57,333,460 RGD:6480464
G Cxcr4 C-X-C motif chemokine receptor 4 JBrowse link 13 45,314,952 45,318,856 RGD:6480464
G Fgf21 fibroblast growth factor 21 JBrowse link 1 101,595,579 101,596,822 RGD:6480464
G Hk2 hexokinase 2 JBrowse link 4 113,559,396 113,609,897 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19741
    role 19688
      application 19339
        MALDI matrix material 911
          alpha-cyano-4-hydroxycinnamic acid 4
Path 2
Term Annotations click to browse term
  CHEBI ontology 19741
    subatomic particle 19737
      composite particle 19737
        hadron 19737
          baryon 19737
            nucleon 19737
              atomic nucleus 19737
                atom 19737
                  main group element atom 19622
                    p-block element atom 19622
                      carbon group element atom 19515
                        carbon atom 19508
                          organic molecular entity 19508
                            organic group 18423
                              organic divalent group 18414
                                organodiyl group 18414
                                  carbonyl group 18301
                                    carbonyl compound 18301
                                      carboxylic acid 17966
                                        monocarboxylic acid 17265
                                          alpha,beta-unsaturated monocarboxylic acid 11335
                                            cinnamic acids 2359
                                              hydroxycinnamic acid 1239
                                                monohydroxycinnamic acid 904
                                                  alpha-cyano-4-hydroxycinnamic acid 4
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.