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Accession:CHEBI:64355 term browser browse the term
Definition:An N-arylpiperazine that consists of piperazine carrying two 4-substituted phenyl groups at positions 1 and 4. A triazole antifungal drug.
Synonyms:exact_synonym: 2,5-anhydro-1,3,4-trideoxy-2-(2,4-difluorophenyl)-4-({4-[4-(4-{1-[(2S,3S)-2-hydroxypentan-3-yl]-5-oxo-1,5-dihydro-4H-1,2,4-triazol-4-yl}phenyl)piperazin-1-yl]phenoxy}methyl)-1-(1H-1,2,4-triazol-1-yl)-D-threo-pentitol
 related_synonym: Formula=C37H42F2N8O4;   InChI=1S/C37H42F2N8O4/c1-3-35(26(2)48)47-36(49)46(25-42-47)31-7-5-29(6-8-31)43-14-16-44(17-15-43)30-9-11-32(12-10-30)50-20-27-19-37(51-21-27,22-45-24-40-23-41-45)33-13-4-28(38)18-34(33)39/h4-13,18,23-27,35,48H,3,14-17,19-22H2,1-2H3/t26-,27+,35-,37-/m0/s1;   InChIKey=RAGOYPUPXAKGKH-XAKZXMRKSA-N;   Noxafil;   SCH56592;   SMILES=CC[C@@H]([C@H](C)O)n1ncn(-c2ccc(cc2)N2CCN(CC2)c2ccc(OC[C@@H]3CO[C@](Cn4cncn4)(C3)c3ccc(F)cc3F)cc2)c1=O;   Sch 56592;   Schering 56592
 xref: CAS:171228-49-2 "ChemIDplus";   CAS:171228-49-2 "KEGG DRUG";   DrugBank:DB01263;   Drug_Central:3483 "DrugCentral";   KEGG:D02555
 xref_mesh: MESH:C101425
 xref: PMID:21762211 "Europe PMC";   PMID:21967490 "Europe PMC";   PMID:22058198 "Europe PMC";   PMID:22176629 "Europe PMC";   PMID:22215361 "Europe PMC";   PMID:22215487 "Europe PMC";   PMID:22286158 "Europe PMC";   PMID:22290952 "Europe PMC";   PMID:22303909 "Europe PMC";   PMID:22324990 "Europe PMC";   PMID:22330929 "Europe PMC";   PMID:22380765 "Europe PMC";   PMID:22391464 "Europe PMC";   PMID:22391534 "Europe PMC";   PMID:22427614 "Europe PMC";   Patent:US5661151;   Patent:WO9517407;   Reaxys:8379448 "Reaxys";   Wikipedia:Posaconazole

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posaconazole term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcb11 ATP binding cassette subfamily B member 11 JBrowse link 3 55,480,024 55,587,946 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19741
    role 19688
      biological role 19686
        antimicrobial agent 17215
          antimicrobial drug 6127
            antiprotozoal drug 3739
              trypanocidal drug 74
                posaconazole 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19741
    subatomic particle 19737
      composite particle 19737
        hadron 19737
          baryon 19737
            nucleon 19737
              atomic nucleus 19737
                atom 19737
                  main group element atom 19622
                    p-block element atom 19622
                      carbon group element atom 19515
                        carbon atom 19508
                          organic molecular entity 19508
                            organic molecule 19431
                              organic cyclic compound 19197
                                organic heterocyclic compound 18267
                                  heteroarene 15809
                                    monocyclic heteroarene 13124
                                      azole 12254
                                        triazoles 3602
                                          triazole antifungal agent 2351
                                            triazole antifungal drug 57
                                              posaconazole 1
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.