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ONTOLOGY REPORT - ANNOTATIONS


Term:alternariol
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Accession:CHEBI:64983 term browser browse the term
Definition:A benzochromenone that is 6H-benzo[c]chromen-6-one which is substituted by a methyl group at position 1 and by hydroxy groups at positions 3, 7, and 9. It is the most important mycotoxin produced by the black mould Alternaria species, which are the most common mycoflora infecting small grain cereals worldwide.
Synonyms:exact_synonym: 3,7,9-trihydroxy-1-methyl-6H-benzo[c]chromen-6-one
 related_synonym: 3,4',5-trihydroxy-6'-methyldibenzo-alpha-pyrone;   3,4,4'-trihydroxy-6'-methyl-2-biphenylcarboxylic acid gamma-lactone;   AOH;   Formula=C14H10O5;   InChI=1S/C14H10O5/c1-6-2-7(15)5-11-12(6)9-3-8(16)4-10(17)13(9)14(18)19-11/h2-5,15-17H,1H3;   InChIKey=CEBXXEKPIIDJHL-UHFFFAOYSA-N;   SMILES=Cc1cc(O)cc2oc(=O)c3c(O)cc(O)cc3c12
 xref: CAS:641-38-3 "ChemIDplus";   CAS:641-38-3 "KEGG COMPOUND";   KEGG:C16838;   KNApSAcK:C00023663;   KNApSAcK:C00023664
 xref_mesh: MESH:C005197
 xref: PMID:15822993 "Europe PMC";   PMID:16464542 "Europe PMC";   PMID:18727009 "Europe PMC";   PMID:19530709 "Europe PMC";   PMID:20687560 "Europe PMC";   PMID:21351248 "Europe PMC";   PMID:21534631 "Europe PMC";   PMID:21579450 "Europe PMC";   PMID:22120949 "Europe PMC";   PMID:22289771 "Europe PMC";   PMID:22406678 "Europe PMC";   PMID:22510154 "Europe PMC";   PMID:22542754 "Europe PMC";   PMID:22613072 "Europe PMC";   PMID:3899714 "Europe PMC";   PMID:4406099 "Europe PMC";   PMID:7986060 "Europe PMC";   Reaxys:244839 "Reaxys";   Wikipedia:Alternariol


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alternariol term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ahr aryl hydrocarbon receptor JBrowse link 6 54,963,990 55,001,806 RGD:6480464
G Ar androgen receptor JBrowse link X 67,656,253 67,828,998 RGD:6480464
G Arnt aryl hydrocarbon receptor nuclear translocator JBrowse link 2 196,594,178 196,651,486 RGD:6480464
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:6480464
G Casp9 caspase 9 JBrowse link 5 160,356,211 160,373,774 RGD:6480464
G Ccnd1 cyclin D1 JBrowse link 1 218,090,750 218,100,447 RGD:6480464
G Cd68 Cd68 molecule JBrowse link 10 56,268,726 56,270,605 RGD:6480464
G Cd83 CD83 molecule JBrowse link 17 24,416,651 24,435,790 RGD:6480464
G Cd86 CD86 molecule JBrowse link 11 67,060,305 67,117,990 RGD:6480464
G Creb1 cAMP responsive element binding protein 1 JBrowse link 9 71,229,753 71,298,994 RGD:6480464
G Cyp11b3 cytochrome P450, family 11, subfamily b, polypeptide 3 JBrowse link 7 116,155,928 116,161,781 RGD:6480464
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 JBrowse link 1 266,422,127 266,429,947 RGD:6480464
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 JBrowse link 8 58,744,849 58,772,408 RGD:6480464
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 JBrowse link 8 62,472,087 62,478,122 RGD:6480464
G Gsr glutathione-disulfide reductase JBrowse link 16 62,197,617 62,239,987 RGD:6480464
G Gsta1 glutathione S-transferase alpha 1 JBrowse link 9 27,366,404 27,381,004 RGD:6480464
G Gsta2 glutathione S-transferase alpha 2 JBrowse link 8 85,640,081 85,645,621 RGD:6480464
G H2ax H2A.X variant histone JBrowse link 8 48,665,652 48,666,981 RGD:6480464
G Hsd3b2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 JBrowse link 2 200,712,895 200,722,429 RGD:6480464
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:6480464
G Itgam integrin subunit alpha M JBrowse link 1 199,495,312 199,545,738 RGD:6480464
G Mc2r melanocortin 2 receptor JBrowse link 18 64,166,959 64,178,729 RGD:6480464
G Mir192 microRNA 192 JBrowse link 1 221,634,971 221,635,080 RGD:6480464
G Mir224 microRNA 224 JBrowse link X 152,223,754 152,223,835 RGD:6480464
G Mtor mechanistic target of rapamycin kinase JBrowse link 5 165,263,813 165,373,967 RGD:6480464
G Nfe2l2 nuclear factor, erythroid 2-like 2 JBrowse link 3 62,497,568 62,525,146 RGD:6480464
G Nr0b1 nuclear receptor subfamily 0, group B, member 1 JBrowse link X 54,734,385 54,738,513 RGD:6480464
G Pgr progesterone receptor JBrowse link 8 7,128,656 7,187,796 RGD:6480464
G Ptger2 prostaglandin E receptor 2 JBrowse link 15 19,336,029 19,349,759 RGD:6480464
G Ptger4 prostaglandin E receptor 4 JBrowse link 2 54,951,625 54,966,470 RGD:6480464
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:6480464
G Rps6kb1 ribosomal protein S6 kinase B1 JBrowse link 10 73,824,200 73,865,503 RGD:6480464
G Sesn2 sestrin 2 JBrowse link 5 150,684,891 150,703,846 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464
G Top2a DNA topoisomerase II alpha JBrowse link 10 86,901,467 86,930,947 RGD:6480464
G Top2b DNA topoisomerase II beta JBrowse link 15 10,262,972 10,319,741 RGD:6480464
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19716
    role 19663
      biological role 19661
        biochemical role 19179
          metabolite 19151
            alternariol 37
              djalonensone 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19716
    subatomic particle 19712
      composite particle 19712
        hadron 19712
          baryon 19712
            nucleon 19712
              atomic nucleus 19712
                atom 19712
                  main group element atom 19598
                    p-block element atom 19598
                      carbon group element atom 19486
                        carbon atom 19480
                          organic molecular entity 19480
                            organic molecule 19402
                              organic cyclic compound 19158
                                organic heterocyclic compound 18245
                                  organic heteropolycyclic compound 17500
                                    organic heterotricyclic compound 13738
                                      benzochromene 67
                                        benzochromenone 53
                                          alternariol 37
                                            djalonensone 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.