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ONTOLOGY REPORT - ANNOTATIONS


Term:iloperidone
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Accession:CHEBI:65173 term browser browse the term
Definition:A member of the class of piperidines that is the 4-acetyl-2-methoxyphenyl ether of 3-(piperidin-1-yl)propan-1-ol which is substituted at position 4 of the piperidine ring by a 6-fluoro-1,2-benzoxazol-3-yl group. A member of the group of second generation antipsychotics (also known as an atypical antipsychotics), it is used for the treatment of schizophrenia.
Synonyms:exact_synonym: 1-(4-{3-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]propoxy}-3-methoxyphenyl)ethanone
 related_synonym: 1-[4-[3-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1- piperidinyl]propoxy]-3-methoxyphenyl]ethanone;   4'-(3-(4-(6-fluoro-1,2-benzisoxazol-3-yl)piperidino)propoxy)-3'-methoxyacetophenone;   Fanapt;   Fanapta;   Formula=C24H27FN2O4;   InChI=1S/C24H27FN2O4/c1-16(28)18-4-7-21(23(14-18)29-2)30-13-3-10-27-11-8-17(9-12-27)24-20-6-5-19(25)15-22(20)31-26-24/h4-7,14-15,17H,3,8-13H2,1-2H3;   InChIKey=XMXHEBAFVSFQEX-UHFFFAOYSA-N;   SMILES=COc1cc(ccc1OCCCN1CCC(CC1)c1noc2cc(F)ccc12)C(C)=O;   Zomaril;   iloperidona;   iloperidonum
 xref: CAS:133454-47-4 "ChemIDplus";   CAS:133454-47-4 "SUBMITTER";   Drug_Central:3294 "DrugCentral";   KEGG:D02666 "SUBMITTER";   LINCS:LSM-5598
 xref_mesh: MESH:C081732
 xref: PMID:21289324 "Europe PMC";   PMID:21474903 "Europe PMC";   PMID:21600386 "Europe PMC";   PMID:22161738 "Europe PMC";   PMID:22217439 "Europe PMC";   PMID:22453868 "Europe PMC";   PMID:22465688 "Europe PMC";   PMID:22617084 "Europe PMC";   Reaxys:7233425 "Reaxys";   Wikipedia:Iloperidone


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iloperidone term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcb11 ATP binding cassette subfamily B member 11 JBrowse link 3 55,480,024 55,587,946 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19728
    role 19675
      biological role 19673
        pharmacological role 18793
          neurotransmitter agent 16396
            serotonergic drug 3917
              serotonergic antagonist 2224
                iloperidone 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19728
    subatomic particle 19724
      composite particle 19724
        hadron 19724
          baryon 19724
            nucleon 19724
              atomic nucleus 19724
                atom 19724
                  main group element atom 19610
                    p-block element atom 19610
                      carbon group element atom 19501
                        carbon atom 19494
                          organic molecular entity 19494
                            organic molecule 19417
                              organic cyclic compound 19184
                                organic heterocyclic compound 18262
                                  organic heteropolycyclic compound 17570
                                    organic heterobicyclic compound 16240
                                      benzoxazole 112
                                        benzisoxazole 71
                                          1,2-benzoxazoles 71
                                            iloperidone 1
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