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Term:ancistrotanzanine A
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Accession:CHEBI:65406 term browser browse the term
Definition:An isoquinoline alkaloid that is (3S)-6,8-dimethoxy-1,3-dimethyl-3,4-dihydroisoquinoline substituted by a 1-hydroxy-8-methoxy-3-methylnaphthalen-2-yl group at position 5. It is isolated from the leaves of Ancistrocladus tanzaniensis and exhibits antiplasmodial, antileishmanial and antitrypanocidal activities.
Synonyms:exact_synonym: 2-[(3S)-6,8-dimethoxy-1,3-dimethyl-3,4-dihydroisoquinolin-5-yl]-8-methoxy-3-methylnaphthalen-1-ol
 related_synonym: Formula=C25H27NO4;   InChI=1S/C25H27NO4/c1-13-10-16-8-7-9-18(28-4)23(16)25(27)21(13)24-17-11-14(2)26-15(3)22(17)19(29-5)12-20(24)30-6/h7-10,12,14,27H,11H2,1-6H3/t14-/m0/s1;   InChIKey=QGIHYQPVZRSTNP-AWEZNQCLSA-N;   SMILES=COc1cc(OC)c(c2C[C@H](C)N=C(C)c12)-c1c(C)cc2cccc(OC)c2c1O
 xref: PMID:12889879;   PMID:14510589;   PMID:15165131;   Reaxys:9816658

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      biological role 0
        biochemical role 0
          metabolite 0
            ancistrotanzanine A 0
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  CHEBI ontology 0
    subatomic particle 0
      composite particle 0
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          baryon 0
            nucleon 0
              atomic nucleus 0
                atom 0
                  main group element atom 0
                    p-block element atom 0
                      carbon group element atom 0
                        carbon atom 0
                          organic molecular entity 0
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                              organic cyclic compound 0
                                carbocyclic compound 0
                                  carbopolycyclic compound 0
                                    carbobicyclic compound 0
                                      naphthalenes 0
                                        hydroxynaphthalene 0
                                          naphthols 0
                                            ancistrotanzanine A 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.