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Term:ancistrotanzanine A
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Accession:CHEBI:65406 term browser browse the term
Definition:An isoquinoline alkaloid that is (3S)-6,8-dimethoxy-1,3-dimethyl-3,4-dihydroisoquinoline substituted by a 1-hydroxy-8-methoxy-3-methylnaphthalen-2-yl group at position 5. It is isolated from the leaves of Ancistrocladus tanzaniensis and exhibits antiplasmodial, antileishmanial and antitrypanocidal activities.
Synonyms:exact_synonym: 2-[(3S)-6,8-dimethoxy-1,3-dimethyl-3,4-dihydroisoquinolin-5-yl]-8-methoxy-3-methylnaphthalen-1-ol
 related_synonym: Formula=C25H27NO4;   InChI=1S/C25H27NO4/c1-13-10-16-8-7-9-18(28-4)23(16)25(27)21(13)24-17-11-14(2)26-15(3)22(17)19(29-5)12-20(24)30-6/h7-10,12,14,27H,11H2,1-6H3/t14-/m0/s1;   InChIKey=QGIHYQPVZRSTNP-AWEZNQCLSA-N;   SMILES=COc1cc(OC)c(c2C[C@H](C)N=C(C)c12)-c1c(C)cc2cccc(OC)c2c1O
 xref: PMID:12889879;   PMID:14510589;   PMID:15165131;   Reaxys:9816658

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  CHEBI ontology 225
    role 225
      biological role 225
        biochemical role 186
          metabolite 179
            ancistrotanzanine A 0
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  CHEBI ontology 225
    subatomic particle 225
      composite particle 225
        hadron 225
          baryon 225
            nucleon 225
              atomic nucleus 225
                atom 225
                  main group element atom 218
                    p-block element atom 218
                      carbon group element atom 207
                        carbon atom 206
                          organic molecular entity 206
                            organic molecule 200
                              organic cyclic compound 184
                                carbocyclic compound 91
                                  carbopolycyclic compound 11
                                    carbobicyclic compound 6
                                      naphthalenes 5
                                        hydroxynaphthalene 4
                                          naphthols 4
                                            ancistrotanzanine A 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.