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Term:ancistrotanzanine A
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Accession:CHEBI:65406 term browser browse the term
Definition:An isoquinoline alkaloid that is (3S)-6,8-dimethoxy-1,3-dimethyl-3,4-dihydroisoquinoline substituted by a 1-hydroxy-8-methoxy-3-methylnaphthalen-2-yl group at position 5. It is isolated from the leaves of Ancistrocladus tanzaniensis and exhibits antiplasmodial, antileishmanial and antitrypanocidal activities.
Synonyms:exact_synonym: 2-[(3S)-6,8-dimethoxy-1,3-dimethyl-3,4-dihydroisoquinolin-5-yl]-8-methoxy-3-methylnaphthalen-1-ol
 related_synonym: Formula=C25H27NO4;   InChI=1S/C25H27NO4/c1-13-10-16-8-7-9-18(28-4)23(16)25(27)21(13)24-17-11-14(2)26-15(3)22(17)19(29-5)12-20(24)30-6/h7-10,12,14,27H,11H2,1-6H3/t14-/m0/s1;   InChIKey=QGIHYQPVZRSTNP-AWEZNQCLSA-N;   SMILES=COc1cc(OC)c(c2C[C@H](C)N=C(C)c12)-c1c(C)cc2cccc(OC)c2c1O
 xref: PMID:12889879;   PMID:14510589;   PMID:15165131;   Reaxys:9816658

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  CHEBI ontology 23948
    role 23836
      biological role 23799
        biochemical role 23134
          metabolite 23030
            ancistrotanzanine A 0
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  CHEBI ontology 23948
    subatomic particle 23899
      composite particle 23899
        hadron 23899
          baryon 23899
            nucleon 23899
              atomic nucleus 23899
                atom 23899
                  main group element atom 23720
                    p-block element atom 23720
                      carbon group element atom 23436
                        carbon atom 23392
                          organic molecular entity 23392
                            organic molecule 23256
                              organic cyclic compound 22275
                                carbocyclic compound 19936
                                  carbopolycyclic compound 16080
                                    carbobicyclic compound 4562
                                      naphthalenes 3712
                                        hydroxynaphthalene 237
                                          naphthols 230
                                            ancistrotanzanine A 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.