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Term:ancistrotanzanine A
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Accession:CHEBI:65406 term browser browse the term
Definition:An isoquinoline alkaloid that is (3S)-6,8-dimethoxy-1,3-dimethyl-3,4-dihydroisoquinoline substituted by a 1-hydroxy-8-methoxy-3-methylnaphthalen-2-yl group at position 5. It is isolated from the leaves of Ancistrocladus tanzaniensis and exhibits antiplasmodial, antileishmanial and antitrypanocidal activities.
Synonyms:exact_synonym: 2-[(3S)-6,8-dimethoxy-1,3-dimethyl-3,4-dihydroisoquinolin-5-yl]-8-methoxy-3-methylnaphthalen-1-ol
 related_synonym: Formula=C25H27NO4;   InChI=1S/C25H27NO4/c1-13-10-16-8-7-9-18(28-4)23(16)25(27)21(13)24-17-11-14(2)26-15(3)22(17)19(29-5)12-20(24)30-6/h7-10,12,14,27H,11H2,1-6H3/t14-/m0/s1;   InChIKey=QGIHYQPVZRSTNP-AWEZNQCLSA-N;   SMILES=COc1cc(OC)c(c2C[C@H](C)N=C(C)c12)-c1c(C)cc2cccc(OC)c2c1O
 xref: PMID:12889879;   PMID:14510589;   PMID:15165131;   Reaxys:9816658

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  CHEBI ontology 21260
    role 21244
      biological role 21242
        biochemical role 20288
          metabolite 20227
            ancistrotanzanine A 0
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  CHEBI ontology 21260
    subatomic particle 21256
      composite particle 21256
        hadron 21256
          baryon 21256
            nucleon 21256
              atomic nucleus 21256
                atom 21256
                  main group element atom 21125
                    p-block element atom 21125
                      carbon group element atom 20894
                        carbon atom 20785
                          organic molecular entity 20785
                            organic molecule 20668
                              organic cyclic compound 20127
                                carbocyclic compound 18312
                                  carbopolycyclic compound 15357
                                    carbobicyclic compound 4605
                                      naphthalenes 3768
                                        hydroxynaphthalene 233
                                          naphthols 226
                                            ancistrotanzanine A 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.