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Term:ancistrotanzanine A
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Accession:CHEBI:65406 term browser browse the term
Definition:An isoquinoline alkaloid that is (3S)-6,8-dimethoxy-1,3-dimethyl-3,4-dihydroisoquinoline substituted by a 1-hydroxy-8-methoxy-3-methylnaphthalen-2-yl group at position 5. It is isolated from the leaves of Ancistrocladus tanzaniensis and exhibits antiplasmodial, antileishmanial and antitrypanocidal activities.
Synonyms:exact_synonym: 2-[(3S)-6,8-dimethoxy-1,3-dimethyl-3,4-dihydroisoquinolin-5-yl]-8-methoxy-3-methylnaphthalen-1-ol
 related_synonym: Formula=C25H27NO4;   InChI=1S/C25H27NO4/c1-13-10-16-8-7-9-18(28-4)23(16)25(27)21(13)24-17-11-14(2)26-15(3)22(17)19(29-5)12-20(24)30-6/h7-10,12,14,27H,11H2,1-6H3/t14-/m0/s1;   InChIKey=QGIHYQPVZRSTNP-AWEZNQCLSA-N;   SMILES=COc1cc(OC)c(c2C[C@H](C)N=C(C)c12)-c1c(C)cc2cccc(OC)c2c1O
 xref: PMID:12889879;   PMID:14510589;   PMID:15165131;   Reaxys:9816658

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  CHEBI ontology 844
    role 821
      biological role 821
        biochemical role 695
          metabolite 679
            ancistrotanzanine A 0
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  CHEBI ontology 844
    subatomic particle 828
      composite particle 828
        hadron 828
          baryon 828
            nucleon 828
              atomic nucleus 828
                atom 828
                  main group element atom 816
                    p-block element atom 813
                      carbon group element atom 784
                        carbon atom 780
                          organic molecular entity 780
                            organic molecule 698
                              organic cyclic compound 619
                                carbocyclic compound 162
                                  carbopolycyclic compound 27
                                    carbobicyclic compound 15
                                      naphthalenes 9
                                        hydroxynaphthalene 0
                                          naphthols 0
                                            ancistrotanzanine A 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.