Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:loxtidine
go back to main search page
Accession:CHEBI:6550 term browser browse the term
Definition:A triazole that consists of 1,2,4-triazole bearing a methyl substituent at position 1, a hydroxymethyl substituent at position 3 and a {3-[3-(piperidin-1-ylmethyl)phenoxy]propyl}amino group at position 5. A highly potent and selective H2-receptor antagonist.
Synonyms:exact_synonym: [1-methyl-5-({3-[3-(piperidin-1-ylmethyl)phenoxy]propyl}amino)-1H-1,2,4-triazol-3-yl]methanol
 related_synonym: Formula=C19H29N5O2;   InChI=1S/C19H29N5O2/c1-23-19(21-18(15-25)22-23)20-9-6-12-26-17-8-5-7-16(13-17)14-24-10-3-2-4-11-24/h5,7-8,13,25H,2-4,6,9-12,14-15H2,1H3,(H,20,21,22);   InChIKey=VTLNPNNUIJHJQB-UHFFFAOYSA-N;   Lavoltidine;   Loxtidina;   Loxtidinum;   SMILES=Cn1nc(CO)nc1NCCCOc1cccc(CN2CCCCC2)c1;   lavoltidina;   lavoltidinum
 xref: CAS:76956-02-0 "ChemIDplus";   CAS:76956-02-0 "KEGG COMPOUND";   KEGG:C11805
 xref_mesh: MESH:C039993
 xref: PMID:10219966 "Europe PMC";   PMID:11025361 "Europe PMC";   PMID:15940630 "Europe PMC";   PMID:1600050 "Europe PMC";   PMID:2038267 "Europe PMC";   PMID:2568467 "Europe PMC";   PMID:2883848 "Europe PMC";   PMID:2895888 "Europe PMC";   PMID:4041682 "Europe PMC";   PMID:6145595 "Europe PMC";   PMID:7605857 "Europe PMC";   PMID:8026255 "Europe PMC";   PMID:9131722 "Europe PMC";   Reaxys:6876968 "Reaxys";   Wikipedia:Loxtidine


show annotations for term's descendants       view all columns           Sort by:
 
loxtidine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Areg amphiregulin JBrowse link 14 18,521,921 18,531,179 RGD:6480464
G Reg1a regenerating family member 1 alpha JBrowse link 4 109,497,962 109,500,626 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19654
    role 19598
      biological role 19596
        pharmacological role 18671
          antagonist 15792
            histamine antagonist 4481
              H2-receptor antagonist 200
                loxtidine 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19654
    subatomic particle 19650
      composite particle 19650
        hadron 19650
          baryon 19650
            nucleon 19650
              atomic nucleus 19650
                atom 19650
                  main group element atom 19531
                    p-block element atom 19531
                      carbon group element atom 19413
                        carbon atom 19405
                          organic molecular entity 19405
                            organic molecule 19327
                              organic cyclic compound 19076
                                organic heterocyclic compound 18151
                                  heteroarene 15151
                                    monocyclic heteroarene 11614
                                      azole 10473
                                        triazoles 3604
                                          loxtidine 2
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.