Term: | lucidenic acid N |
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Accession: | CHEBI:66595
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Definition: | A tetracyclic triterpenoid that is 25,26,27-trinorlanost-8-en-24-oic acid substituted by hydroxy groups at positions 3 and 7 and oxo groups at positions 11 and 15 respectively (the 3beta,5alpha,7beta stereoisomer). Isolated from the fruiting bodies of Ganoderma lucidum, it exhibits cytotoxicity against tumour cells. |
Synonyms: | exact_synonym: | (3beta,5alpha,7beta)-3,7-dihydroxy-4,4,14-trimethyl-11,15-dioxochol-8-en-24-oic acid |
| related_synonym: | 3,7-Dihydroxy-25,26,27-trinor-11,15-dioxolanost-8-en-24-oic acid; Formula=C27H40O6; InChI=1S/C27H40O6/c1-14(7-8-21(32)33)15-11-20(31)27(6)23-16(28)12-18-24(2,3)19(30)9-10-25(18,4)22(23)17(29)13-26(15,27)5/h14-16,18-19,28,30H,7-13H2,1-6H3,(H,32,33)/t14-,15-,16+,18+,19+,25+,26-,27+/m1/s1; InChIKey=YBGBNHHXOJXFNM-UQCMLMITSA-N; SMILES=[H][C@@]1(CC(=O)[C@@]2(C)C3=C(C(=O)C[C@]12C)[C@@]1(C)CC[C@H](O)C(C)(C)[C@]1([H])C[C@@H]3O)[C@H](C)CCC(O)=O |
| xref: | Chemspider:10213993; HMDB:HMDB0038352 |
| xref_mesh: | MESH:C437028 |
| xref: | PMID:11520245 "Europe PMC"; PMID:18422750 "Europe PMC"; PMID:21924611 "Europe PMC"; Reaxys:8956644 "Reaxys" |
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