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Term:mallotophilippen D
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Accession:CHEBI:66658 term browser browse the term
Definition:A member of the class of chalcones that is chalcone substituted by hydroxy groups at positions 3, 4, 2' and 4', a geranyl group at position 3' and a 6,6-dimethyl-3,6-dihydro-2H-pyran ring fused across positions 5' and 6'. Isolated from the fruits of Mallotus philippensis, it exhibits anti-inflammatory and immunoregulatory activities.
Synonyms:exact_synonym: (2E)-3-(3,4-dihydroxyphenyl)-1-{6-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-5,7-dihydroxy-2,2-dimethyl-2H-chromen-8-yl}prop-2-en-1-one
 related_synonym: Formula=C30H34O6;   InChI=1S/C30H34O6/c1-18(2)7-6-8-19(3)9-12-21-27(34)22-15-16-30(4,5)36-29(22)26(28(21)35)24(32)14-11-20-10-13-23(31)25(33)17-20/h7,9-11,13-17,31,33-35H,6,8,12H2,1-5H3/b14-11+,19-9+;   InChIKey=NBJRNHOFHFJPDJ-GSFKWRMWSA-N;   SMILES=CC(C)=CCC\\C(C)=C\\Cc1c(O)c2C=CC(C)(C)Oc2c(C(=O)\\C=C\\c2ccc(O)c(O)c2)c1O
 xref: PMID:15516755 "Europe PMC";   Reaxys:9886501 "Reaxys"

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  CHEBI ontology 19748
    role 19695
      application 19350
        anti-inflammatory agent 14955
          mallotophilippen D 0
Path 2
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  CHEBI ontology 19748
    subatomic particle 19744
      composite particle 19744
        hadron 19744
          baryon 19744
            nucleon 19744
              atomic nucleus 19744
                atom 19744
                  main group element atom 19628
                    p-block element atom 19628
                      carbon group element atom 19522
                        carbon atom 19516
                          organic molecular entity 19516
                            organic group 18426
                              organic divalent group 18418
                                organodiyl group 18418
                                  carbonyl group 18306
                                    carbonyl compound 18306
                                      ketone 15922
                                        alpha,beta-unsaturated ketone 8413
                                          enone 8413
                                            chalcones 131
                                              mallotophilippen D 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.