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Accession:CHEBI:66697 term browser browse the term
Definition:A member of the class of psoralens that is psoralen substituted by a methoxy group at position 4 and a [(2R)-3-butoxy-2-hydroxy-3-methylbutyl]oxy group at position 9. Isolated from the roots of Angelica dahurica, it exhibits inhibitory activity against COX-2 and 5-lipooxygenase.
Synonyms:exact_synonym: 9-{[(2R)-3-butoxy-2-hydroxy-3-methylbutyl]oxy}-4-methoxy-7H-furo[3,2-g]chromen-7-one
 related_synonym: Formula=C21H26O7;   InChI=1S/C21H26O7/c1-5-6-10-27-21(2,3)15(22)12-26-20-18-14(9-11-25-18)17(24-4)13-7-8-16(23)28-19(13)20/h7-9,11,15,22H,5-6,10,12H2,1-4H3/t15-/m1/s1;   InChIKey=HYFWQORTIZQRLZ-OAHLLOKOSA-N;   SMILES=CCCCOC(C)(C)[C@H](O)COc1c2occc2c(OC)c2ccc(=O)oc12
 xref: PMID:18481018 "Europe PMC"

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Term Annotations click to browse term
  CHEBI ontology 19734
    role 19680
      biological role 19678
        biochemical role 19177
          metabolite 19147
            5-methoxy-8-(2'-hydroxy-3'-buthoxy-3'-methylbutyloxy)psoralen 0
Path 2
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  CHEBI ontology 19734
    subatomic particle 19730
      composite particle 19730
        hadron 19730
          baryon 19730
            nucleon 19730
              atomic nucleus 19730
                atom 19730
                  main group element atom 19614
                    p-block element atom 19614
                      carbon group element atom 19506
                        carbon atom 19500
                          organic molecular entity 19500
                            organic molecule 19418
                              organic cyclic compound 19189
                                organic heterocyclic compound 18267
                                  organic heteropolycyclic compound 17572
                                    organic heterotricyclic compound 13735
                                      furochromene 99
                                        furanocoumarin 99
                                          psoralens 91
                                            psoralen 76
                                              5-methoxy-8-(2'-hydroxy-3'-buthoxy-3'-methylbutyloxy)psoralen 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.