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ONTOLOGY REPORT - ANNOTATIONS


Term:mangiferin
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Accession:CHEBI:6682 term browser browse the term
Definition:A C-glycosyl compound consisting of 1,3,6,7-tetrahydroxyxanthen-9-one having a beta-D-glucosyl residue at the 6-position.
Synonyms:exact_synonym: 2-beta-D-glucopyranosyl-1,3,6,7-tetrahydroxy-9H-xanthen-9-one
 related_synonym: (1S)-1,5-anhydro-1-(1,3,6,7-tetrahydroxy-9-oxo-9H-xanthen-2-yl)-D-glucitol;   Alpizarin;   Aphloiol;   Chinomin;   Chinonin;   Formula=C19H18O11;   Hedysarid;   InChI=1S/C19H18O11/c20-4-11-15(25)17(27)18(28)19(30-11)12-8(23)3-10-13(16(12)26)14(24)5-1-6(21)7(22)2-9(5)29-10/h1-3,11,15,17-23,25-28H,4H2/t11-,15-,17+,18-,19+/m1/s1;   InChIKey=AEDDIBAIWPIIBD-ZJKJAXBQSA-N;   SMILES=[H][C@]1(O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)c1c(O)cc2oc3cc(O)c(O)cc3c(=O)c2c1O
 xref: Beilstein:65853 "Beilstein";   CAS:4773-96-0 "ChemIDplus";   CAS:4773-96-0 "KEGG COMPOUND";   KEGG:C10077;   KNApSAcK:C00002962
 xref_mesh: MESH:C013592
 xref: PMID:10705751 "Europe PMC";   PMID:11978432 "Europe PMC";   PMID:12377236 "Europe PMC";   PMID:12951446 "Europe PMC";   PMID:15182859 "Europe PMC";   Reaxys:65853 "Reaxys";   Wikipedia:Mangiferin


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mangiferin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcb1a ATP-binding cassette, sub-family B (MDR/TAP), member 1A JBrowse link 5 8,567,091 8,748,575 RGD:6480464
G Abl1 c-abl oncogene 1, non-receptor tyrosine kinase JBrowse link 2 31,688,244 31,807,093 RGD:6480464
G Acaca acetyl-Coenzyme A carboxylase alpha JBrowse link 11 84,129,635 84,401,651 RGD:6480464
G Ache acetylcholinesterase JBrowse link 5 137,288,247 137,294,466 RGD:6480464
G Acp5 acid phosphatase 5, tartrate resistant JBrowse link 9 22,126,727 22,135,746 RGD:6480464
G Ager advanced glycosylation end product-specific receptor JBrowse link 17 34,597,460 34,600,937 RGD:6480464
G Agt angiotensinogen (serpin peptidase inhibitor, clade A, member 8) JBrowse link 8 124,556,587 124,569,706 RGD:6480464
G Agtr1a angiotensin II receptor, type 1a JBrowse link 13 30,336,356 30,382,867 RGD:6480464
G Aifm1 apoptosis-inducing factor, mitochondrion-associated 1 JBrowse link X 48,474,944 48,513,563 RGD:6480464
G Akt1 thymoma viral proto-oncogene 1 JBrowse link 12 112,653,821 112,674,884 RGD:6480464
G Alb albumin JBrowse link 5 90,460,870 90,476,602 RGD:6480464
G Apaf1 apoptotic peptidase activating factor 1 JBrowse link 10 90,989,311 91,082,743 RGD:6480464
G Atp6v0d2 ATPase, H+ transporting, lysosomal V0 subunit D2 JBrowse link 4 19,876,838 19,922,566 RGD:6480464
G Bax BCL2-associated X protein JBrowse link 7 45,461,695 45,466,903 RGD:6480464
G Bcl2 B cell leukemia/lymphoma 2 JBrowse link 1 106,538,176 106,714,290 RGD:6480464
G Bcl2l1 BCL2-like 1 JBrowse link 2 152,758,732 152,833,803 RGD:6480464
G Birc5 baculoviral IAP repeat-containing 5 JBrowse link 11 117,849,237 117,855,743 RGD:6480464
G C3 complement component 3 JBrowse link 17 57,203,967 57,228,136 RGD:6480464
G Calcr calcitonin receptor JBrowse link 6 3,685,680 3,764,713 RGD:6480464
G Casp3 caspase 3 JBrowse link 8 46,617,291 46,639,698 RGD:6480464
G Casp9 caspase 9 JBrowse link 4 141,793,612 141,815,978 RGD:6480464
G Cat catalase JBrowse link 2 103,453,904 103,485,153 RGD:6480464
G Ccl2 chemokine (C-C motif) ligand 2 JBrowse link 11 82,035,577 82,037,452 RGD:6480464
G Ccl5 chemokine (C-C motif) ligand 5 JBrowse link 11 83,525,778 83,530,518 RGD:6480464
G Ccnb1 cyclin B1 JBrowse link 13 100,778,739 100,786,486 RGD:6480464
G Cd36 CD36 molecule JBrowse link 5 17,781,690 17,888,959 RGD:6480464
G Cdh1 cadherin 1 JBrowse link 8 106,603,350 106,670,247 RGD:6480464
G Cdk1 cyclin-dependent kinase 1 JBrowse link 10 69,335,146 69,352,912 RGD:6480464
G Chuk conserved helix-loop-helix ubiquitous kinase JBrowse link 19 44,073,334 44,107,505 RGD:6480464
G Col1a1 collagen, type I, alpha 1 JBrowse link 11 94,936,224 94,953,042 RGD:6480464
G Col4a1 collagen, type IV, alpha 1 JBrowse link 8 11,198,423 11,312,889 RGD:6480464
G Cpt1a carnitine palmitoyltransferase 1a, liver JBrowse link 19 3,322,326 3,385,735 RGD:6480464
G Csf2 colony stimulating factor 2 (granulocyte-macrophage) JBrowse link 11 54,247,270 54,249,899 RGD:6480464
G Csf3 colony stimulating factor 3 (granulocyte) JBrowse link 11 98,700,183 98,703,631 RGD:6480464
G Ctnnb1 catenin (cadherin associated protein), beta 1 JBrowse link 9 120,933,400 120,960,507 RGD:6480464
G Ctnnd1 catenin (cadherin associated protein), delta 1 JBrowse link 2 84,587,096 84,658,977 RGD:6480464
G Ctsd cathepsin D JBrowse link 7 142,375,910 142,387,827 RGD:6480464
G Ctsk cathepsin K JBrowse link 3 95,499,210 95,509,387 RGD:6480464
G Cxcl15 chemokine (C-X-C motif) ligand 15 JBrowse link 5 90,794,534 90,803,067 RGD:6480464
G Cxcr4 chemokine (C-X-C motif) receptor 4 JBrowse link 1 128,588,199 128,592,299 RGD:6480464
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 JBrowse link 9 57,687,928 57,703,824 RGD:6480464
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 JBrowse link 9 57,676,937 57,683,655 RGD:6480464
G Cyp2a4 cytochrome P450, family 2, subfamily a, polypeptide 4 JBrowse link 7 26,307,192 26,315,088 RGD:6480464
G Cyp2b10 cytochrome P450, family 2, subfamily b, polypeptide 10 JBrowse link 7 25,897,658 25,926,624 RGD:6480464
G Cyp2c38 cytochrome P450, family 2, subfamily c, polypeptide 38 JBrowse link 19 39,389,556 39,463,103 RGD:6480464
G Cyp2c65 cytochrome P450, family 2, subfamily c, polypeptide 65 JBrowse link 19 39,061,006 39,093,948 RGD:6480464
G Cyp2c66 cytochrome P450, family 2, subfamily c, polypeptide 66 JBrowse link 19 39,113,898 39,186,756 RGD:6480464
G Cyp2d22 cytochrome P450, family 2, subfamily d, polypeptide 22 JBrowse link 15 82,370,527 82,380,260 RGD:6480464
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 JBrowse link 7 140,763,819 140,774,990 RGD:6480464
G Cyp3a11 cytochrome P450, family 3, subfamily a, polypeptide 11 JBrowse link 5 145,854,607 145,879,854 RGD:6480464
G Dcstamp dendrocyte expressed seven transmembrane protein JBrowse link 15 39,745,930 39,760,938 RGD:6480464
G Dgat2 diacylglycerol O-acyltransferase 2 JBrowse link 7 99,153,663 99,182,713 RGD:6480464
G Dnm1l dynamin 1-like JBrowse link 16 16,312,228 16,359,038 RGD:6480464
G F10 coagulation factor X JBrowse link 8 13,037,308 13,056,676 RGD:6480464
G Fas Fas (TNF receptor superfamily member 6) JBrowse link 19 34,290,647 34,327,775 RGD:6480464
G Fbp1 fructose bisphosphatase 1 JBrowse link 13 62,864,753 62,888,298 RGD:6480464
G Fn1 fibronectin 1 JBrowse link 1 71,585,473 71,653,280 RGD:6480464
G Gcg glucagon JBrowse link 2 62,474,530 62,483,653 RGD:6480464
G Glo1 glyoxalase 1 JBrowse link 17 30,592,861 30,612,659 RGD:6480464
G Gpt glutamic pyruvic transaminase, soluble JBrowse link 15 76,696,726 76,699,675 RGD:6480464
G Gsr glutathione reductase JBrowse link 8 33,653,238 33,698,162 RGD:6480464
G Gusb glucuronidase, beta JBrowse link 5 129,989,011 130,003,049 RGD:6480464
G Hmox1 heme oxygenase 1 JBrowse link 8 75,093,618 75,100,593 RGD:6480464
G Icam1 intercellular adhesion molecule 1 JBrowse link 9 21,015,940 21,028,814 RGD:6480464
G Icam2 intercellular adhesion molecule 2 JBrowse link 11 106,377,656 106,388,139 RGD:6480464
G Icam5 intercellular adhesion molecule 5, telencephalin JBrowse link 9 21,032,038 21,039,036 RGD:6480464
G Ifna1 interferon alpha 1 JBrowse link 4 88,850,087 88,850,656 RGD:6480464
G Ifnb1 interferon beta 1, fibroblast JBrowse link 4 88,522,025 88,522,794 RGD:6480464
G Ifng interferon gamma JBrowse link 10 118,441,046 118,445,894 RGD:6480464
G Ikbkb inhibitor of kappaB kinase beta JBrowse link 8 22,659,205 22,706,589 RGD:6480464
G Il10 interleukin 10 JBrowse link 1 131,019,845 131,024,970 RGD:6480464
G Il12a interleukin 12a JBrowse link 3 68,690,644 68,698,550 RGD:6480464
G Il12b interleukin 12b JBrowse link 11 44,400,063 44,414,677 RGD:6480464
G Il18 interleukin 18 JBrowse link 9 50,554,700 50,581,841 RGD:6480464
G Il1a interleukin 1 alpha JBrowse link 2 129,299,609 129,310,186 RGD:6480464
G Il1b interleukin 1 beta JBrowse link 2 129,364,569 129,371,164 RGD:6480464
G Il2rb interleukin 2 receptor, beta chain JBrowse link 15 78,479,256 78,511,621 RGD:6480464
G Il6 interleukin 6 JBrowse link 5 30,013,114 30,019,975 RGD:6480464
G Irf1 interferon regulatory factor 1 JBrowse link 11 53,769,854 53,778,374 RGD:6480464
G Lpl lipoprotein lipase JBrowse link 8 68,880,555 68,906,932 RGD:6480464
G Map3k14 mitogen-activated protein kinase kinase kinase 14 JBrowse link 11 103,219,764 103,267,401 RGD:6480464
G Mapk1 mitogen-activated protein kinase 1 JBrowse link 16 16,983,382 17,047,453 RGD:6480464
G Mapk3 mitogen-activated protein kinase 3 JBrowse link 7 126,759,626 126,765,816 RGD:6480464
G Mapk8 mitogen-activated protein kinase 8 JBrowse link 14 33,377,898 33,447,353 RGD:6480464
G Mapk9 mitogen-activated protein kinase 9 JBrowse link 11 49,846,728 49,886,421 RGD:6480464
G Max Max protein JBrowse link 12 76,937,269 76,962,323 RGD:6480464
G Mmp7 matrix metallopeptidase 7 JBrowse link 9 7,692,090 7,699,585 RGD:6480464
G Mmp9 matrix metallopeptidase 9 JBrowse link 2 164,940,326 164,955,850 RGD:6480464
G Mpo myeloperoxidase JBrowse link 11 87,793,784 87,804,412 RGD:6480464
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 JBrowse link 2 75,675,513 75,704,663 RGD:6480464
G Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 JBrowse link 3 135,584,655 135,691,969 RGD:6480464
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha JBrowse link 12 55,489,409 55,492,647 RGD:6480464
G Nfkbib nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta JBrowse link 7 28,758,251 28,766,644 RGD:6480464
G Nfkbie nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, epsilon JBrowse link 17 45,555,700 45,563,169 RGD:6480464
G Nfkbil1 nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor like 1 JBrowse link 17 35,220,175 35,236,481 RGD:6480464
G Ngf nerve growth factor JBrowse link 3 102,469,919 102,521,013 RGD:6480464
G Nos2 nitric oxide synthase 2, inducible JBrowse link 11 78,920,787 78,960,226 RGD:6480464
G Nqo1 NAD(P)H dehydrogenase, quinone 1 JBrowse link 8 107,388,225 107,403,205 RGD:6480464
G Pla2g2a phospholipase A2, group IIA (platelets, synovial fluid) JBrowse link 4 138,831,857 138,835,189 RGD:6480464
G Plau plasminogen activator, urokinase JBrowse link 14 20,836,662 20,843,388 RGD:6480464
G Ppara peroxisome proliferator activated receptor alpha JBrowse link 15 85,734,910 85,806,851 RGD:6480464
G Pparg peroxisome proliferator activated receptor gamma JBrowse link 6 115,360,879 115,490,404 RGD:6480464
G Prkaa1 protein kinase, AMP-activated, alpha 1 catalytic subunit JBrowse link 15 5,143,861 5,181,899 RGD:6480464
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 1 150,100,031 150,108,234 RGD:6480464
G Raf1 v-raf-leukemia viral oncogene 1 JBrowse link 6 115,618,569 115,676,635 RGD:6480464
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) JBrowse link 19 5,637,442 5,648,134 RGD:6480464
G Relb avian reticuloendotheliosis viral (v-rel) oncogene related B JBrowse link 7 19,606,217 19,629,438 RGD:6480464
G Ripk1 receptor (TNFRSF)-interacting serine-threonine kinase 1 JBrowse link 13 34,002,225 34,035,170 RGD:6480464
G Saa1 serum amyloid A 1 JBrowse link 7 46,740,497 46,743,181 RGD:6480464
G Sele selectin, endothelial cell JBrowse link 1 164,039,614 164,058,487 RGD:6480464
G Selplg selectin, platelet (p-selectin) ligand JBrowse link 5 113,817,798 113,832,528 RGD:6480464
G Serpine1 serine (or cysteine) peptidase inhibitor, clade E, member 1 JBrowse link 5 137,061,504 137,072,272 RGD:6480464
G Slc22a1 solute carrier family 22 (organic cation transporter), member 1 JBrowse link 17 12,648,874 12,675,838 RGD:6480464
G Slc22a12 solute carrier family 22 (organic anion/cation transporter), member 12 JBrowse link 19 6,535,854 6,543,070 RGD:6480464
G Slc22a2 solute carrier family 22 (organic cation transporter), member 2 JBrowse link 17 12,584,189 12,628,489 RGD:6480464
G Slc22a4 solute carrier family 22 (organic cation transporter), member 4 JBrowse link 11 53,983,115 54,030,040 RGD:6480464
G Slc22a5 solute carrier family 22 (organic cation transporter), member 5 JBrowse link 11 53,864,542 53,891,796 RGD:6480464
G Slc2a4 solute carrier family 2 (facilitated glucose transporter), member 4 JBrowse link 11 69,942,286 69,948,216 RGD:6480464
G Snai1 snail family zinc finger 1 JBrowse link 2 167,538,195 167,542,814 RGD:6480464
G Snai2 snail family zinc finger 2 JBrowse link 16 14,705,852 14,709,395 RGD:6480464
G Sod1 superoxide dismutase 1, soluble JBrowse link 16 90,220,762 90,226,333 RGD:6480464
G Srd5a2 steroid 5 alpha-reductase 2 JBrowse link 17 74,014,891 74,047,860 RGD:6480464
G Srf serum response factor JBrowse link 17 46,546,838 46,558,267 RGD:6480464
G Tab1 TGF-beta activated kinase 1/MAP3K7 binding protein 1 JBrowse link 15 80,133,127 80,161,707 RGD:6480464
G Tbk1 TANK-binding kinase 1 JBrowse link 10 121,546,455 121,586,794 RGD:6480464
G Tert telomerase reverse transcriptase JBrowse link 13 73,626,911 73,649,843 RGD:6480464
G Tgfb1 transforming growth factor, beta 1 JBrowse link 7 25,687,002 25,705,077 RGD:6480464
G Tlr6 toll-like receptor 6 JBrowse link 5 64,952,030 64,970,942 RGD:6480464
G Tlr7 toll-like receptor 7 JBrowse link X 167,303,380 167,330,574 RGD:6480464
G Tlr8 toll-like receptor 8 JBrowse link X 167,241,123 167,264,329 RGD:6480464
G Tlr9 toll-like receptor 9 JBrowse link 9 106,222,598 106,226,876 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 17 35,199,367 35,202,007 RGD:6480464
G Tnfrsf11a tumor necrosis factor receptor superfamily, member 11a, NFKB activator JBrowse link 1 105,780,673 105,849,444 RGD:6480464
G Tnfsf11 tumor necrosis factor (ligand) superfamily, member 11 JBrowse link 14 78,277,446 78,308,043 RGD:6480464
G Tradd TNFRSF1A-associated via death domain JBrowse link 8 105,258,575 105,264,594 RGD:6480464
G Traf6 TNF receptor-associated factor 6 JBrowse link 2 101,678,420 101,701,668 RGD:6480464
G Trp53 transformation related protein 53 JBrowse link 11 69,580,348 69,591,873 RGD:6480464
G Ugt1a1 UDP glucuronosyltransferase 1 family, polypeptide A1 JBrowse link 1 88,211,959 88,220,002 RGD:6480464
G Ugt1a9 UDP glucuronosyltransferase 1 family, polypeptide A9 JBrowse link 1 88,070,779 88,220,002 RGD:6480464
G Ugt2b34 UDP glucuronosyltransferase 2 family, polypeptide B34 JBrowse link 5 86,889,770 86,906,937 RGD:6480464
G Umod uromodulin JBrowse link 7 119,462,708 119,479,262 RGD:6480464
G Vcam1 vascular cell adhesion molecule 1 JBrowse link 3 116,110,020 116,129,688 RGD:6480464
G Vegfa vascular endothelial growth factor A JBrowse link 17 46,016,993 46,032,377 RGD:6480464
G Vim vimentin JBrowse link 2 13,574,311 13,582,826 RGD:6480464
G Xiap X-linked inhibitor of apoptosis JBrowse link X 42,059,613 42,109,664 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 21021
    role 21002
      chemical role 20344
        antioxidant 14266
          mangiferin 145
Path 2
Term Annotations click to browse term
  CHEBI ontology 21021
    subatomic particle 21015
      composite particle 21015
        hadron 21015
          baryon 21015
            nucleon 21015
              atomic nucleus 21015
                atom 21015
                  main group element atom 20858
                    p-block element atom 20858
                      carbon group element atom 20599
                        carbon atom 20576
                          organic molecular entity 20576
                            organic group 19171
                              organic divalent group 19161
                                organodiyl group 19161
                                  carbonyl group 19133
                                    carbonyl compound 19133
                                      ketone 16245
                                        cyclic ketone 13501
                                          xanthones 168
                                            xanthone 147
                                              mangiferin 145
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.