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Term:meclofenamic acid
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Accession:CHEBI:6710 term browser browse the term
Definition:An aminobenzoic acid that is anthranilic acid in which one of the hydrogens attached to the nitrogen is replaced by a 2,6-dichloro-3-methylphenyl group. A non-steroidal anti-inflammatory drug, it is used as the sodium salt for the treatment of dysmenorrhoea (painful periods), osteoarthritis and rheumatoid arthritis.
Synonyms:exact_synonym: 2-[(2,6-dichloro-3-methylphenyl)amino]benzoic acid
 related_synonym: CI-583;   Formula=C14H11Cl2NO2;   INF 4668;   InChI=1S/C14H11Cl2NO2/c1-8-6-7-10(15)13(12(8)16)17-11-5-3-2-4-9(11)14(18)19/h2-7,17H,1H3,(H,18,19);   InChIKey=SBDNJUWAMKYJOX-UHFFFAOYSA-N;   N-(2,6-dichloro-3-methylphenyl)anthranilic acid;   N-(2,6-dichloro-m-tolyl)anthranilic acid;   N-(3-methyl-2,6-dichlorophenyl)anthranilic acid;   SMILES=Cc1ccc(Cl)c(Nc2ccccc2C(O)=O)c1Cl;   acide meclofenamique;   acido meclofenamico;   acidum meclofenamicum
 xref: CAS:644-62-2 "ChemIDplus";   CAS:644-62-2 "KEGG COMPOUND";   CAS:644-62-2 "NIST Chemistry WebBook";   DrugBank:DB00939;   Drug_Central:1650 "DrugCentral";   HMDB:HMDB0015074;   KEGG:C07117;   KEGG:D02341;   LINCS:LSM-3108
 xref_mesh: MESH:D008469
 xref: PDBeChem:JMS;   PMID:15598972 "Europe PMC";   PMID:16986603 "Europe PMC";   PMID:17348907 "Europe PMC";   PMID:1810521 "Europe PMC";   PMID:19279153 "Europe PMC";   PMID:21660425 "Europe PMC";   PMID:23534549 "Europe PMC";   PMID:23567745 "Europe PMC";   PMID:23584353 "Europe PMC";   PMID:322627 "Europe PMC";   PMID:7349327 "Europe PMC";   Patent:DE1149045;   Patent:US3313848;   Reaxys:2221428 "Reaxys";   Wikipedia:Meclofenamic_acid
 cyclic_relationship: is_conjugate_acid_of CHEBI:76230

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meclofenamic acid term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akr1c1 aldo-keto reductase family 1, member C1 JBrowse link 17 69,441,253 69,460,334 RGD:6480464
G Akr1c2 aldo-keto reductase family 1, member C2 JBrowse link 17 69,388,337 69,435,160 RGD:6480464
G Akr1c3 aldo-keto reductase family 1, member C3 JBrowse link 17 69,761,126 69,778,021 RGD:6480464
G Alox5 arachidonate 5-lipoxygenase JBrowse link 4 148,398,004 148,446,308 RGD:6480464
G Ren renin JBrowse link 13 50,502,724 50,513,953 RGD:6480464
G Sell selectin L JBrowse link 13 82,369,820 82,387,774 RGD:6480464
G Slc16a2 solute carrier family 16 member 2 JBrowse link X 74,578,600 74,706,068 RGD:6480464
G Sult1a1 sulfotransferase family 1A member 1 JBrowse link 1 198,100,586 198,104,106 RGD:6480464
G Sult1e1 sulfotransferase family 1E member 1 JBrowse link 14 22,070,861 22,089,264 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464
G Ugt2b7 UDP glucuronosyltransferase family 2 member B7 JBrowse link 14 22,597,103 22,619,968 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19728
    role 19675
      biological role 19673
        pharmacological role 18793
          analgesic 13046
            meclofenamic acid 11
Path 2
Term Annotations click to browse term
  CHEBI ontology 19728
    subatomic particle 19724
      composite particle 19724
        hadron 19724
          baryon 19724
            nucleon 19724
              atomic nucleus 19724
                atom 19724
                  main group element atom 19610
                    p-block element atom 19610
                      carbon group element atom 19501
                        carbon atom 19494
                          organic molecular entity 19494
                            organic group 18413
                              organic divalent group 18404
                                organodiyl group 18404
                                  carbonyl group 18293
                                    carbonyl compound 18293
                                      carboxylic acid 17960
                                        aromatic carboxylic acid 10732
                                          benzoic acids 10698
                                            aminobenzoic acid 1607
                                              meclofenamic acid 11
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