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Term:cortistatin D
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Accession:CHEBI:67175 term browser browse the term
Definition:A member of the class of cortistatins that is cortistatin C in which the hydrogen at position 17 has been replaced by a hydroxy group.
Synonyms:exact_synonym: (1R,2R,3S,5R)-3-(dimethylamino)-1,2,17alpha-trihydroxy-17beta-(isoquinolin-7-yl)-5,8alpha-epoxy-9,19-cyclo-9,10-secoandrosta-9(11),10-dien-16-one
 related_synonym: (1R,2R,3S,5R,8alpha,17alpha)-3-(dimethylamino)-1,2,17-trihydroxy-17-(isoquinolin-7-yl)-5,8-epoxy-9,19-cyclo-9,10-secoandrosta-9(11),10-dien-16-one;   Formula=C30H34N2O5;   InChI=1S/C30H34N2O5/c1-27-8-6-19-13-21-25(34)26(35)22(32(2)3)15-28(21)9-10-29(19,37-28)23(27)14-24(33)30(27,36)20-5-4-17-7-11-31-16-18(17)12-20/h4-7,11-13,16,22-23,25-26,34-36H,8-10,14-15H2,1-3H3/t22-,23+,25+,26+,27-,28+,29+,30+/m0/s1;   InChIKey=VSVYWUPPYDXESC-OMXDIREYSA-N;   SMILES=[H][C@@]12CC(=O)[C@](O)(c3ccc4ccncc4c3)[C@@]1(C)CC=C1C=C3[C@@H](O)[C@H](O)[C@H](C[C@]33CC[C@]21O3)N(C)C
 xref: PMID:16522087 "Europe PMC";   PMID:17765550 "Europe PMC";   Reaxys:10504489 "Reaxys"

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  CHEBI ontology 19754
    role 19701
      application 19353
        pharmaceutical 19222
          drug 19222
            angiogenesis modulating agent 1480
              cortistatins 0
                cortistatin D 0
Path 2
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  CHEBI ontology 19754
    subatomic particle 19752
      composite particle 19752
        hadron 19752
          baryon 19752
            nucleon 19752
              atomic nucleus 19752
                atom 19752
                  main group element atom 19637
                    main group molecular entity 19637
                      s-block molecular entity 19397
                        hydrogen molecular entity 19386
                          hydrides 18356
                            inorganic hydride 17216
                              pnictogen hydride 17180
                                nitrogen hydride 17014
                                  azane 16706
                                    ammonia 16703
                                      organic amino compound 16702
                                        tertiary amino compound 8585
                                          cortistatins 0
                                            cortistatin A 0
                                              cortistatin B 0
                                                cortistatin C 0
                                                  cortistatin D 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.