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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:Methandrostenolone
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Accession:CHEBI:6810 term browser browse the term
Synonyms:related_synonym: DIANABOL (TN);   Formula=C20H28O2;   InChI=1S/C20H28O2/c1-18-9-6-14(21)12-13(18)4-5-15-16(18)7-10-19(2)17(15)8-11-20(19,3)22/h6,9,12,15-17,22H,4-5,7-8,10-11H2,1-3H3/t15-,16+,17+,18+,19+,20+/m1/s1;   InChIKey=XWALNWXLMVGSFR-HLXURNFRSA-N;   SMILES=C[C@@]12[C@@]3([C@]([C@]4([C@@](CC3)(C)[C@@](CC4)(C)O)[H])(CCC1=CC(C=C2)=O)[H])[H];   dehydromethyltestosterone;   metanabol;   metandienon;   metandienonum;   metandrostenolon;   metandrostenolone;   methandienone;   methandrolone;   methylboldenone
 xref: CAS:72-63-9;   Drug_Central:1734;   HMDB:HMDB0041925;   KEGG:D00389
 xref_mesh: MESH:D008696


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Methandrostenolone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor decreases expression EXP Methandrostenolone results in decreased expression of AR mRNA CTD PMID:21818626 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Cyp11b2 cytochrome P450, family 11, subfamily b, polypeptide 2 increases metabolic processing
increases chemical synthesis
ISO CYP11B1 protein results in increased metabolism of Methandrostenolone
CYP11B1 protein results in increased chemical synthesis of Methandrostenolone analog
CTD PMID:22885098 NCBI chr 7:116,248,759...116,255,205
Ensembl chr 7:116,156,219...116,255,167
JBrowse link
G Cyp11b3 cytochrome P450, family 11, subfamily b, polypeptide 3 increases chemical synthesis
increases metabolic processing
ISO CYP11B2 protein results in increased chemical synthesis of Methandrostenolone analog
CYP11B2 protein results in increased metabolism of Methandrostenolone
CTD PMID:22885098 NCBI chr 7:116,155,928...116,161,781
Ensembl chr 7:116,156,219...116,255,167
JBrowse link
G Fst follistatin decreases expression EXP Methandrostenolone results in decreased expression of FST mRNA CTD PMID:21818626 NCBI chr 2:46,537,589...46,544,813
Ensembl chr 2:46,538,700...46,544,457
JBrowse link
G Lhb luteinizing hormone subunit beta decreases secretion EXP Methandrostenolone results in decreased secretion of LHB protein CTD PMID:21818626 NCBI chr 1:101,409,992...101,413,725
Ensembl chr 1:101,410,019...101,413,724
JBrowse link
G Mstn myostatin increases expression EXP Methandrostenolone results in increased expression of MSTN mRNA CTD PMID:21818626 NCBI chr 9:53,310,977...53,315,804
Ensembl chr 9:53,309,598...53,315,915
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19810
    chemical entity 19810
      atom 19808
        nonmetal atom 19683
          carbon atom 19588
            organic molecular entity 19588
              Methandrostenolone 6
Path 2
Term Annotations click to browse term
  CHEBI ontology 19810
    subatomic particle 19808
      composite particle 19808
        hadron 19808
          baryon 19808
            nucleon 19808
              atomic nucleus 19808
                atom 19808
                  main group element atom 19696
                    p-block element atom 19696
                      carbon group element atom 19599
                        carbon atom 19588
                          organic molecular entity 19588
                            Methandrostenolone 6
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.