Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   


go back to main search page
Accession:CHEBI:6821 term browser browse the term
Definition:A member of the class of quinazolines that is quinazolin-4-one substituted at positions 2 and 3 by methyl and o-tolyl groups respectively. A depressant that increases the activity of the GABA receptors in the brain and nervous system, it is used as a sedative and hypnotic medication. It became popular as a recreational drug and club drug in the late 1960s and 1970s.
Synonyms:exact_synonym: 2-methyl-3-(2-methylphenyl)quinazolin-4(3H)-one
 related_synonym: Formula=C16H14N2O;   InChI=1S/C16H14N2O/c1-11-7-3-6-10-15(11)18-12(2)17-14-9-5-4-8-13(14)16(18)19/h3-10H,1-2H3;   InChIKey=JEYCTXHKTXCGPB-UHFFFAOYSA-N;   SMILES=N1(C=2C(=CC=CC2)C)C(C3=C(C=CC=C3)N=C1C)=O;   metacualona;   methaqualonum
 xref: CAS:72-44-6 "ChemIDplus";   PMID:11672968 "Europe PMC";   PMID:15846700 "Europe PMC";   PMID:16566774 "Europe PMC";   PMID:16861151 "Europe PMC";   PMID:22019312 "Europe PMC";   PMID:26056160 "Europe PMC";   PMID:2701316 "Europe PMC";   PMID:28166217 "Europe PMC";   PMID:3397524 "Europe PMC"

show annotations for term's descendants       view all columns           Sort by:

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19754
    role 19701
      biological role 19700
        pharmacological role 18807
          neurotransmitter agent 16417
            GABA agent 15442
              GABA agonist 3818
                methaqualone 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19754
    subatomic particle 19752
      composite particle 19752
        hadron 19752
          baryon 19752
            nucleon 19752
              atomic nucleus 19752
                atom 19752
                  main group element atom 19637
                    p-block element atom 19637
                      p-block molecular entity 19637
                        carbon group molecular entity 19528
                          organic molecular entity 19517
                            organic molecule 19436
                              organic cyclic compound 19199
                                organic heterocyclic compound 18276
                                  organic heteropolycyclic compound 17583
                                    organic heterobicyclic compound 16252
                                      quinazolines 450
                                        methaqualone 0
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.