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Accession:CHEBI:68534 term browser browse the term
Definition:A benzamide obtained by formal condensation of the carboxy group of 4-{3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl}-2-fluorobenzoic acid with methylamine. Used for the treatment of of metastatic castration-resistant prostate cancer.
Synonyms:exact_synonym: 4-{3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl}-2-fluoro-N-methylbenzamide
 related_synonym: Formula=C21H16F4N4O2S;   InChI=1S/C21H16F4N4O2S/c1-20(2)18(31)28(12-5-4-11(10-26)15(8-12)21(23,24)25)19(32)29(20)13-6-7-14(16(22)9-13)17(30)27-3/h4-9H,1-3H3,(H,27,30);   InChIKey=WXCXUHSOUPDCQV-UHFFFAOYSA-N;   MDV 3100;   MDV3100;   SMILES=CNC(=O)c1ccc(cc1F)N1C(=S)N(C(=O)C1(C)C)c1ccc(C#N)c(c1)C(F)(F)F;   XTANDI
 xref: CAS:915087-33-1 "ChemIDplus";   Drug_Central:4628 "DrugCentral";   LINCS:LSM-6254;   PMID:21986558 "Europe PMC";   PMID:22101903 "Europe PMC";   PMID:22113551 "Europe PMC";   PMID:22162475 "Europe PMC";   PMID:22229405 "Europe PMC";   PMID:22258371 "Europe PMC";   PMID:22258374 "Europe PMC";   PMID:22266222 "Europe PMC";   PMID:22310230 "Europe PMC";   PMID:22373838 "Europe PMC";   PMID:22393799 "Europe PMC";   PMID:22411952 "Europe PMC";   PMID:22429837 "Europe PMC";   PMID:22472508 "Europe PMC";   PMID:22516457 "Europe PMC";   PMID:22710436 "Europe PMC";   PMID:22815001 "Europe PMC";   PMID:22845410 "Europe PMC";   PMID:22852027 "Europe PMC";   PMID:22894553 "Europe PMC";   PMID:22956944 "Europe PMC";   PMID:22985411 "Europe PMC";   PMID:22987974 "Europe PMC";   Patent:US2007254933;   Patent:WO2006124118;   Patent:WO2011106570;   Reaxys:11718700 "Reaxys";   Wikipedia:Enzalutamide

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Path 1
Term Annotations click to browse term
  CHEBI ontology 19654
    chemical entity 19652
      group 19568
        pseudohalo group 2769
          cyano group 2769
            nitrile 2769
              enzalutamide 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19654
    subatomic particle 19650
      composite particle 19650
        hadron 19650
          baryon 19650
            nucleon 19650
              atomic nucleus 19650
                atom 19650
                  main group element atom 19531
                    p-block element atom 19531
                      carbon group element atom 19413
                        carbon atom 19405
                          organic molecular entity 19405
                            organic group 18331
                              organic divalent group 18321
                                organodiyl group 18321
                                  carbonyl group 18209
                                    carbonyl compound 18209
                                      carboxylic acid 17908
                                        carboacyl group 16930
                                          univalent carboacyl group 16930
                                            carbamoyl group 16610
                                              carboxamide 16610
                                                monocarboxylic acid amide 13174
                                                  arenecarboxamide 6402
                                                    benzamides 6402
                                                      enzalutamide 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.