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ONTOLOGY REPORT - ANNOTATIONS


Term:chetomin
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Accession:CHEBI:68741 term browser browse the term
Definition:An organic heteropentacyclic compound of the class of epipolythiodioxopiperazine. Isolated from Chaetomium globosum and Farrowia seminuda, it exhibits immunosuppressive activity.
Synonyms:exact_synonym: 3-(hydroxymethyl)-10b-(3-{[4-(hydroxymethyl)-5,7-dimethyl-6,8-dioxo-2,3-dithia-5,7-diazabicyclo[2.2.2]oct-1-yl]methyl}-1H-indol-1-yl)-2-methyl-2,3,5a,6,10b,11-hexahydro-3,11a-epidithiopyrazino[1',2':1,5]pyrrolo[2,3-b]indole-1,4-dione
 related_synonym: Formula=C31H30N6O6S4;   InChI=1S/C31H30N6O6S4/c1-33-25(42)30(15-38)34(2)23(40)28(33,44-46-30)12-17-13-36(21-11-7-4-8-18(17)21)27-14-29-24(41)35(3)31(16-39,47-45-29)26(43)37(29)22(27)32-20-10-6-5-9-19(20)27/h4-11,13,22,32,38-39H,12,14-16H2,1-3H3;   InChIKey=ZRZWBWPDBOVIGQ-UHFFFAOYSA-N;   SMILES=CN1C(=O)C23CC4(C(Nc5ccccc45)N2C(=O)C1(CO)SS3)n1cc(CC23SSC(CO)(N(C)C2=O)C(=O)N3C)c2ccccc12
 xref: CAS:1403-36-7 "ChemIDplus";   Chemspider:2592
 xref_mesh: MESH:C001598
 xref: PMID:14738397 "Europe PMC";   Reaxys:5722511 "Reaxys"


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chetomin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Edn1 endothelin 1 JBrowse link 17 22,136,814 22,143,745 RGD:6480464
G Hif1a hypoxia inducible factor 1 subunit alpha JBrowse link 6 96,810,868 96,856,303 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464
G Vegfa vascular endothelial growth factor A JBrowse link 9 17,340,341 17,355,681 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19754
    role 19701
      biological role 19700
        immunomodulator 13680
          immunosuppressive agent 11926
            chetomin 4
Path 2
Term Annotations click to browse term
  CHEBI ontology 19754
    subatomic particle 19752
      composite particle 19752
        hadron 19752
          baryon 19752
            nucleon 19752
              atomic nucleus 19752
                atom 19752
                  main group element atom 19637
                    p-block element atom 19637
                      carbon group element atom 19528
                        carbon atom 19517
                          organic molecular entity 19517
                            organic molecule 19436
                              organic cyclic compound 19199
                                organic heterocyclic compound 18276
                                  organic heteropolycyclic compound 17583
                                    organic heterobicyclic compound 16252
                                      benzopyrrole 9339
                                        indoles 9200
                                          chetomin 4
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