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ONTOLOGY REPORT - ANNOTATIONS


Term:ioflupane I(123)
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Accession:CHEBI:68855 term browser browse the term
Definition:An azabicycloalkane that is ecgonine methyl ester in which the N-methyl group is replaced by 3-fluoropropyl and the 3beta-hydroxy group is replaced by 4-((123)I)iodophenyl. Used for the imaging of dopamine transporters in the brain of adult patients with potential Parkinsonian Syndromes.
Synonyms:exact_synonym: methyl (1R,2S,3S,5S)-8-(3-fluoropropyl)-3-[4-((123)I)iodophenyl]-8-azabicyclo[3.2.1]octane-2-carboxylate
 related_synonym: 123I-FP-CIT;   123I-Ioflupane;   Datscan;   Formula=C18H23F[123I]NO2;   InChI=1S/C18H23FINO2/c1-23-18(22)17-15(12-3-5-13(20)6-4-12)11-14-7-8-16(17)21(14)10-2-9-19/h3-6,14-17H,2,7-11H2,1H3/t14-,15+,16+,17-/m0/s1/i20-4;   InChIKey=HXWLAJVUJSVENX-HFIFKADTSA-N;   SMILES=[H][C@]12CC[C@]([H])([C@H]([C@H](C1)c1ccc([123I])cc1)C(=O)OC)N2CCCF;   ioflupano (123I);   ioflupanum (123I)
 xref: CAS:155798-07-5;   Drug_Central:4230;   KEGG:D10014;   PMID:21278615;   PMID:21406999;   PMID:21410815;   PMID:21870999;   PMID:21881474;   PMID:21883027;   PMID:21916850;   PMID:21975260;   PMID:22030322;   PMID:22237674;   PMID:22256203;   PMID:22323748;   PMID:22382608;   PMID:22492213;   PMID:22497105;   PMID:22500370;   PMID:22565571;   PMID:22592286;   PMID:22653326;   PMID:22785531;   PMID:22833860;   PMID:23039635;   PMID:23071169;   Wikipedia:Ioflupane_(123I)


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Term Annotations click to browse term
  CHEBI ontology 19758
    role 19705
      application 19359
        pharmaceutical 19228
          radiopharmaceutical 1
            ioflupane I(123) 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19758
    subatomic particle 19756
      composite particle 19756
        hadron 19756
          baryon 19756
            nucleon 19756
              atomic nucleus 19756
                atom 19756
                  main group element atom 19641
                    p-block element atom 19641
                      carbon group element atom 19532
                        carbon atom 19521
                          organic molecular entity 19521
                            organic group 18428
                              organic divalent group 18419
                                organodiyl group 18419
                                  carbonyl group 18309
                                    carbonyl compound 18309
                                      carboxylic acid 17978
                                        hydroxy carboxylic acid 3595
                                          hydroxy monocarboxylic acid 3595
                                            2-hydroxy monocarboxylic acid 2912
                                              ecgonine 2
                                                ioflupane I(123) 0
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