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ONTOLOGY REPORT - ANNOTATIONS


Term:trichlorfon
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Accession:CHEBI:6908 term browser browse the term
Definition:A phosphonic ester that is dimethyl phosphonate in which the hydrogen atom attched to the phosphorous is substituted by a 2,2,2-trichloro-1-hydroxyethyl group.
Synonyms:exact_synonym: dimethyl (2,2,2-trichloro-1-hydroxyethyl)phosphonate
 related_synonym: 1-Hydroxy-2,2,2-trichloroethylphosphonic acid dimethyl ester;   Chlorophos;   Formula=C4H8Cl3O4P;   InChI=1S/C4H8Cl3O4P/c1-10-12(9,11-2)3(8)4(5,6)7/h3,8H,1-2H3;   InChIKey=NFACJZMKEDPNKN-UHFFFAOYSA-N;   Methyl chlorophos;   Metrifonate;   SMILES=COP(=O)(OC)C(O)C(Cl)(Cl)Cl;   metrifonato;   metrifonatum
 xref: Beilstein:1709434 "Beilstein";   CAS:52-68-6 "ChemIDplus";   CAS:52-68-6 "KEGG COMPOUND";   CAS:52-68-6 "NIST Chemistry WebBook";   Drug_Central:1787 "DrugCentral";   KEGG:C07971;   KEGG:D00805;   LINCS:LSM-4995
 xref_mesh: MESH:D014236
 xref: PMID:19775726 "Europe PMC";   PMID:24122545 "Europe PMC";   PPDB:657;   Reaxys:1709434 "Reaxys";   VSDB:657;   Wikipedia:Metrifonate


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trichlorfon term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ache acetylcholinesterase JBrowse link 12 22,472,358 22,477,052 RGD:6480464
G App amyloid beta precursor protein JBrowse link 11 24,425,013 24,641,872 RGD:6480464
G Bche butyrylcholinesterase JBrowse link 2 171,104,476 171,196,186 RGD:6480464
G Bcl2 BCL2, apoptosis regulator JBrowse link 13 26,605,426 26,769,374 RGD:6480464
G Casp12 caspase 12 JBrowse link 8 2,658,892 2,686,160 RGD:6480464
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:6480464
G Cat catalase JBrowse link 3 93,379,872 93,412,058 RGD:6480464
G Chrm2 cholinergic receptor, muscarinic 2 JBrowse link 4 64,089,028 64,091,090 RGD:6480464
G Chrm4 cholinergic receptor, muscarinic 4 JBrowse link 3 80,833,272 80,841,165 RGD:6480464
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 JBrowse link 8 62,798,317 62,809,848 RGD:6480464
G Fshb follicle stimulating hormone subunit beta JBrowse link 3 98,088,321 98,092,131 RGD:6480464
G Gap43 growth associated protein 43 JBrowse link 11 58,624,198 58,717,916 RGD:6480464
G Hnf4a hepatocyte nuclear factor 4, alpha JBrowse link 3 159,902,441 159,965,003 RGD:6480464
G Nefh neurofilament heavy JBrowse link 14 85,181,572 85,191,557 RGD:6480464
G Nfe2l2 nuclear factor, erythroid 2-like 2 JBrowse link 3 62,497,568 62,525,146 RGD:6480464
G Pnpla6 patatin-like phospholipase domain containing 6 JBrowse link 12 2,068,749 2,098,139 RGD:6480464
G Serpina3m serine (or cysteine) proteinase inhibitor, clade A, member 3M JBrowse link 6 127,808,785 127,816,067 RGD:6480464
G Star steroidogenic acute regulatory protein JBrowse link 16 71,036,204 71,040,847 RGD:6480464
G Syn1 synapsin I JBrowse link X 1,321,315 1,379,202 RGD:6480464
G Syp synaptophysin JBrowse link X 15,694,699 15,709,244 RGD:6480464
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19741
    role 19688
      application 19339
        agrochemical 13445
          trichlorfon 21
Path 2
Term Annotations click to browse term
  CHEBI ontology 19741
    subatomic particle 19737
      composite particle 19737
        hadron 19737
          baryon 19737
            nucleon 19737
              atomic nucleus 19737
                atom 19737
                  main group element atom 19622
                    p-block element atom 19622
                      chalcogen 19334
                        oxygen atom 19295
                          oxygen molecular entity 19295
                            hydroxides 19048
                              oxoacid 18111
                                pnictogen oxoacid 9840
                                  phosphorus oxoacid 8659
                                    phosphorus oxoacid derivative 8122
                                      phosphonic acid derivative 2324
                                        phosphonate 165
                                          organic phosphonate 165
                                            trichlorfon 21
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.