Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:desoximetasone
go back to main search page
Accession:CHEBI:691037 term browser browse the term
Definition:Dexamethasone in which the hydroxy group at the 17alpha position is substituted by hydrogen. A synthetic corticosteroid with glucocorticoid activity, it is used as an anti-inflammatory and anti-pruritic in the treatment of various skin disorders, including skin allergies and psoriasis.
Synonyms:exact_synonym: 9-fluoro-11beta,21-dihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione
 related_synonym: (11beta,16alpha)-9-fluoro-11,21-dihydroxy-16-methylpregna-1,4-diene-3,20-dione;   9alpha-fluoro-16alpha-methyl-Delta(1)-corticosterone;   Formula=C22H29FO4;   InChI=1S/C22H29FO4/c1-12-8-16-15-5-4-13-9-14(25)6-7-21(13,3)22(15,23)18(27)10-20(16,2)19(12)17(26)11-24/h6-7,9,12,15-16,18-19,24,27H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,18+,19-,20+,21+,22+/m1/s1;   InChIKey=VWVSBHGCDBMOOT-IIEHVVJPSA-N;   SMILES=[H][C@@]12C[C@@H](C)[C@H](C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]1(F)[C@@]2([H])CCC2=CC(=O)C=C[C@]12C;   desoximetasona;   desoximetasonum;   desoxymethasone
 xref: Beilstein:2228097 "Beilstein";   CAS:382-67-2 "ChemIDplus";   DrugBank:DB00547;   Drug_Central:819 "DrugCentral";   KEGG:D03697
 xref_mesh: MESH:D003899
 xref: Patent:BE314196;   Patent:FR1296544;   Patent:US3099654;   Patent:US3232839;   Wikipedia:Desoximetasone


show annotations for term's descendants       view all columns           Sort by:
 
desoximetasone term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Slc22a2 solute carrier family 22 member 2 JBrowse link 1 48,318,025 48,360,219 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19741
    role 19688
      application 19339
        anti-inflammatory agent 14942
          anti-inflammatory drug 13591
            desoximetasone 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19741
    subatomic particle 19737
      composite particle 19737
        hadron 19737
          baryon 19737
            nucleon 19737
              atomic nucleus 19737
                atom 19737
                  main group element atom 19622
                    p-block element atom 19622
                      carbon group element atom 19515
                        carbon atom 19508
                          organic molecular entity 19508
                            organic group 18423
                              organic divalent group 18414
                                organodiyl group 18414
                                  carbonyl group 18301
                                    carbonyl compound 18301
                                      ketone 15918
                                        oxyketone 8453
                                          alpha-oxyketone 8453
                                            alpha-hydroxy ketone 8453
                                              primary alpha-hydroxy ketone 7443
                                                desoximetasone 1
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.