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Accession:CHEBI:70168 term browser browse the term
Definition:A member of the class of 2,5-diketopiperazines that is piperazine-2,5-dione substituted by 1H-indol-3-ylmethyl groups at positions 3 and 6 respectively. Isolated from Penicillium species, it exhibits antibacterial activity.
Synonyms:exact_synonym: (3R,6S)-3,6-bis(1H-indol-3-ylmethyl)piperazine-2,5-dione
 related_synonym: Formula=C22H20N4O2;   InChI=1S/C22H20N4O2/c27-21-19(9-13-11-23-17-7-3-1-5-15(13)17)25-22(28)20(26-21)10-14-12-24-18-8-4-2-6-16(14)18/h1-8,11-12,19-20,23-24H,9-10H2,(H,25,28)(H,26,27)/t19-,20+;   InChIKey=DNHODRZUCGXYKU-BGYRXZFFSA-N;   SMILES=O=C1N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H]1Cc1c[nH]c2ccccc12;   cyclo(Trp-Trp);   cyclo-(L-Trp-D-Trp);   fellutanine A
 xref: PMID:10867952 "Europe PMC";   PMID:14520967 "Europe PMC";   PMID:21126094 "Europe PMC";   Reaxys:8651145 "Reaxys"

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  CHEBI ontology 19716
    role 19663
      biological role 19661
        antimicrobial agent 17199
          antibacterial agent 12924
            fellutanine 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19716
    subatomic particle 19712
      composite particle 19712
        hadron 19712
          baryon 19712
            nucleon 19712
              atomic nucleus 19712
                atom 19712
                  main group element atom 19598
                    p-block element atom 19598
                      carbon group element atom 19486
                        carbon atom 19480
                          organic molecular entity 19480
                            organic group 18407
                              organic divalent group 18397
                                organodiyl group 18397
                                  carbonyl group 18285
                                    carbonyl compound 18285
                                      carboxylic acid 17940
                                        carboacyl group 16948
                                          univalent carboacyl group 16948
                                            carbamoyl group 16630
                                              carboxamide 16630
                                                peptide 9315
                                                  cyclic peptide 8717
                                                    homodetic cyclic peptide 8308
                                                      2,5-diketopiperazines 1
                                                        fellutanine 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.