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ONTOLOGY REPORT - ANNOTATIONS


Term:dienogest
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Accession:CHEBI:70708 term browser browse the term
Definition:A steroid hormone that is 17beta-hydroxy-3-oxoestra-4,9-diene substituted at position 17 by a cyanomethyl group. Used as an oral contraceptive.
Synonyms:exact_synonym: [(17beta)-17-hydroxy-3-oxoestra-4,9-dien-17-yl]acetonitrile
 related_synonym: (17-hydroxy-3-oxoestra-4,9-dien-17beta-yl)acetonitrile;   17alpha-Cyanomethyl-17beta-hydroxyestra-4,9(10)-dien-3-one;   Dienogestum;   Formula=C20H25NO2;   InChI=1S/C20H25NO2/c1-19-8-6-16-15-5-3-14(22)12-13(15)2-4-17(16)18(19)7-9-20(19,23)10-11-21/h12,17-18,23H,2-10H2,1H3/t17-,18+,19+,20-/m1/s1;   InChIKey=AZFLJNIPTRTECV-FUMNGEBKSA-N;   SMILES=[H][C@@]12CCC3=CC(=O)CCC3=C1CC[C@@]1(C)[C@@]2([H])CC[C@@]1(O)CC#N
 xref: CAS:65928-58-7 "ChemIDplus";   CAS:65928-58-7 "KEGG DRUG";   Drug_Central:871 "DrugCentral";   KEGG:D03799
 xref_mesh: MESH:C023635
 xref: PMID:21681516 "Europe PMC";   PMID:22003899 "Europe PMC";   PMID:22067805 "Europe PMC";   PMID:22130322 "Europe PMC";   PMID:22149760 "Europe PMC";   PMID:22160205 "Europe PMC";   PMID:22169052 "Europe PMC";   PMID:22264663 "Europe PMC";   PMID:22322156 "Europe PMC";   PMID:22364708 "Europe PMC";   PMID:22366992 "Europe PMC";   PMID:22413833 "Europe PMC";   PMID:22445438 "Europe PMC";   PMID:22459918 "Europe PMC";   PMID:22515510 "Europe PMC";   PMID:22571602 "Europe PMC";   PMID:22876102 "Europe PMC";   PMID:22878119 "Europe PMC";   PMID:23003209 "Europe PMC";   Patent:EP1935898;   Patent:US2008214512;   Patent:US2010298585;   Patent:US6670350;   Patent:WO2008116890;   Patent:WO2011132045;   Reaxys:5763925 "Reaxys";   Wikipedia:Dienogest


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dienogest term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akr1c2 aldo-keto reductase family 1, member C2 JBrowse link 17 69,388,337 69,435,160 RGD:6480464
G Ccl2 C-C motif chemokine ligand 2 JBrowse link 10 69,412,065 69,413,863 RGD:6480464
G Cd4 Cd4 molecule JBrowse link 4 157,381,862 157,408,357 RGD:6480464
G Crp C-reactive protein JBrowse link 13 91,080,448 91,081,358 RGD:6480464
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 JBrowse link 8 58,744,849 58,772,408 RGD:6480464
G F2 coagulation factor II JBrowse link 3 80,529,468 80,542,993 RGD:6480464
G F7 coagulation factor VII JBrowse link 16 81,824,610 81,834,923 RGD:6480464
G Fga fibrinogen alpha chain JBrowse link 2 181,997,562 182,013,726 RGD:6480464
G Fgb fibrinogen beta chain JBrowse link 2 182,028,044 182,035,026 RGD:6480464
G Fgg fibrinogen gamma chain JBrowse link 2 181,987,080 181,994,523 RGD:6480464
G Fshb follicle stimulating hormone subunit beta JBrowse link 3 98,088,321 98,092,131 RGD:6480464
G Hmgb1 high mobility group box 1 JBrowse link 12 7,082,529 7,090,246 RGD:6480464
G Hsd17b2 hydroxysteroid (17-beta) dehydrogenase 2 JBrowse link 19 50,246,404 50,317,892 RGD:6480464
G Igf1 insulin-like growth factor 1 JBrowse link 7 28,412,123 28,491,815 RGD:6480464
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:6480464
G Lhb luteinizing hormone subunit beta JBrowse link 1 101,409,992 101,413,725 RGD:6480464
G Nfkb1 nuclear factor kappa B subunit 1 JBrowse link 2 240,773,520 240,890,053 RGD:6480464
G Plat plasminogen activator, tissue type JBrowse link 16 74,098,263 74,122,897 RGD:6480464
G Proc protein C, inactivator of coagulation factors Va and VIIIa JBrowse link 18 24,918,402 24,928,822 RGD:6480464
G Pros1 protein S JBrowse link 7 1,206,648 1,288,140 RGD:6480464
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:6480464
G Serpinc1 serpin family C member 1 JBrowse link 13 78,806,107 78,820,375 RGD:6480464
G Serpine1 serpin family E member 1 JBrowse link 12 22,641,104 22,651,482 RGD:6480464
G Tlr4 toll-like receptor 4 JBrowse link 5 82,587,424 82,601,056 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19716
    role 19663
      biological role 19661
        molecular messenger 18042
          hormone 17840
            steroid hormone 7732
              dienogest 25
Path 2
Term Annotations click to browse term
  CHEBI ontology 19716
    subatomic particle 19712
      composite particle 19712
        hadron 19712
          baryon 19712
            nucleon 19712
              atomic nucleus 19712
                atom 19712
                  main group element atom 19598
                    p-block element atom 19598
                      carbon group element atom 19486
                        carbon atom 19480
                          organic molecular entity 19480
                            organic group 18407
                              organic divalent group 18397
                                organodiyl group 18397
                                  carbonyl group 18285
                                    carbonyl compound 18285
                                      ketone 15909
                                        oxo steroid 9263
                                          3-oxo steroid 8787
                                            3-oxo-Delta(4) steroid 7910
                                              dienogest 25
paths to the root

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