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Term:pyrazine-2-carboxylic acid
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Accession:CHEBI:71311 term browser browse the term
Definition:The parent compound of the class of pyrazinecarboxylic acids, that is pyrazine bearing a single carboxy substituent. The active metabolite of the antitubercular drug pyrazinamide.
Synonyms:related_synonym: 2-Carboxypyrazine;   2-Pyrazinecarboxylic acid;   Formula=C5H4N2O2;   InChI=1S/C5H4N2O2/c8-5(9)4-3-6-1-2-7-4/h1-3H,(H,8,9);   InChIKey=NIPZZXUFJPQHNH-UHFFFAOYSA-N;   Paradiazinecarboxylic acid;   Pyrazinemonocarboxylic acid;   Pyrazinic acid;   Pyrazinoic acid;   SMILES=OC(=O)c1cnccn1;   pyrazinecarboxylic acid
 xref: CAS:98-97-5 "ChemIDplus";   CAS:98-97-5 "KEGG COMPOUND";   CAS:98-97-5 "NIST Chemistry WebBook";   KEGG:C19915
 xref_mesh: MESH:C005296
 xref: MetaCyc:PYRAZINOIC-ACID;   PDBeChem:VGL;   PMID:19298694 "Europe PMC";   PMID:19963078 "Europe PMC";   PMID:20099263 "Europe PMC";   PMID:20382083 "Europe PMC";   PMID:20429806 "Europe PMC";   PMID:20879713 "Europe PMC";   PMID:21283666 "Europe PMC";   PMID:21775138 "Europe PMC";   PMID:21835980 "Europe PMC";   PMID:21876062 "Europe PMC";   PMID:22004792 "Europe PMC";   PMID:22074423 "Europe PMC";   PMID:22236853 "Europe PMC";   PMID:22372927 "Europe PMC";   PMID:22613684 "Europe PMC";   PMID:23101013 "Europe PMC";   PMID:28166217 "Europe PMC";   Reaxys:112305 "Reaxys";   Wikipedia:Pyrazinoic_acid
 cyclic_relationship: is_conjugate_acid_of CHEBI:71266

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pyrazine-2-carboxylic acid term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acmsd aminocarboxymuconate semialdehyde decarboxylase JBrowse link 13 44,424,689 44,468,734 RGD:6480464
G Slc22a12 solute carrier family 22 member 12 JBrowse link 1 221,910,787 221,919,277 RGD:6480464
G Slc22a6 solute carrier family 22 member 6 JBrowse link 1 224,824,809 224,833,284 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19728
    role 19675
      biological role 19673
        antimicrobial agent 17211
          antibacterial agent 12926
            antibacterial drug 3089
              antimycobacterial drug 961
                antitubercular agent 553
                  pyrazine-2-carboxylic acid 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19728
    subatomic particle 19724
      composite particle 19724
        hadron 19724
          baryon 19724
            nucleon 19724
              atomic nucleus 19724
                atom 19724
                  main group element atom 19610
                    p-block element atom 19610
                      carbon group element atom 19501
                        carbon atom 19494
                          organic molecular entity 19494
                            organic group 18413
                              organic divalent group 18404
                                organodiyl group 18404
                                  carbonyl group 18293
                                    carbonyl compound 18293
                                      carboxylic acid 17960
                                        pyrazinecarboxylic acid 41
                                          pyrazine-2-carboxylic acid 3
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.