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ONTOLOGY REPORT - ANNOTATIONS


Term:nitrofurantoin
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Accession:CHEBI:71415 term browser browse the term
Definition:An imidazolidine-2,4-dione that is hydantoin substituted at position 1 by a [(5-nitro-2-furyl)methylene]amino group. An antibiotic that damages bacterial DNA.
Synonyms:exact_synonym: 1-{[(5-nitro-2-furyl)methylene]amino}imidazolidine-2,4-dione
 related_synonym: 1-((5-Nitrofurfurylidene)amino)hydantoin;   1-(5-Nitro-2-furfurylidenamino)hydantoin;   1-(5-Nitro-2-furfurylideneamino)hydantoin;   5-Nitrofurantoin;   Formula=C8H6N4O5;   InChI=1S/C8H6N4O5/c13-6-4-11(8(14)10-6)9-3-5-1-2-7(17-5)12(15)16/h1-3H,4H2,(H,10,13,14)/b9-3+;   InChIKey=NXFQHRVNIOXGAQ-YCRREMRBSA-N;   N-(5-Nitrofurfurylidene)-1-aminohydantoin;   SMILES=C1(N(/N=C/C=2OC(=CC2)[N+]([O-])=O)CC(N1)=O)=O;   nitrofurantoina;   nitrofurantoine;   nitrofurantoinum
 alt_id: CHEBI:7591
 xref: CAS:67-20-9 "ChemIDplus";   CAS:67-20-9 "KEGG COMPOUND";   CAS:67-20-9 "NIST Chemistry WebBook";   DrugBank:DB00698;   Drug_Central:1949 "DrugCentral";   KEGG:C07268;   KEGG:D00439
 xref_mesh: MESH:D009582
 xref: PMID:21567157 "Europe PMC";   PMID:22240115 "Europe PMC";   PMID:22252772 "Europe PMC";   PMID:22252808 "Europe PMC";   PMID:22285235 "Europe PMC";   PMID:22332195 "Europe PMC";   PMID:22508296 "Europe PMC";   PMID:22535452 "Europe PMC";   PMID:22552451 "Europe PMC";   PMID:22722224 "Europe PMC";   PMID:22779302 "Europe PMC";   PMID:22787489 "Europe PMC";   PMID:22836745 "Europe PMC";   PMID:22857139 "Europe PMC";   PMID:22869929 "Europe PMC";   PMID:22876623 "Europe PMC";   PMID:22923965 "Europe PMC";   PMID:22929632 "Europe PMC";   PMID:22977056 "Europe PMC";   PMID:23016316 "Europe PMC";   PMID:23109011 "Europe PMC";   PMID:23113731 "Europe PMC";   PMID:23114172 "Europe PMC";   Patent:US2610181;   Patent:US2898335;   Patent:US2927110;   Patent:WO2006019844;   Patent:WO2008103673;   Patent:WO2010065110;   Reaxys:8132135 "Reaxys";   Wikipedia:Nitrofurantoin


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nitrofurantoin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcb11 ATP binding cassette subfamily B member 11 JBrowse link 3 55,480,024 55,587,946 RGD:6480464
G Abcb4 ATP binding cassette subfamily B member 4 JBrowse link 4 22,133,984 22,192,687 RGD:6480464
G Abcg2 ATP binding cassette subfamily G member 2 JBrowse link 4 88,765,441 88,890,268 RGD:6480464
G Agt angiotensinogen JBrowse link 19 57,321,594 57,333,460 RGD:6480464
G Aldoa aldolase, fructose-bisphosphate A JBrowse link 1 198,228,387 198,233,988 RGD:6480464
G Cat catalase JBrowse link 3 93,379,872 93,412,058 RGD:6480464
G Cntf ciliary neurotrophic factor JBrowse link 1 229,599,009 229,601,032 RGD:6480464
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 JBrowse link 8 62,472,087 62,478,122 RGD:6480464
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 JBrowse link 8 62,451,360 62,458,244 RGD:6480464
G Gsr glutathione-disulfide reductase JBrowse link 16 62,197,617 62,239,987 RGD:6480464
G Hif1a hypoxia inducible factor 1 subunit alpha JBrowse link 6 96,810,868 96,856,303 RGD:6480464
G Hmox1 heme oxygenase 1 JBrowse link 19 14,508,634 14,515,455 RGD:6480464
G Hspa8 heat shock protein family A (Hsp70) member 8 JBrowse link 8 44,989,401 44,993,261 RGD:6480464
G Jun Jun proto-oncogene, AP-1 transcription factor subunit JBrowse link 5 114,011,184 114,014,277 RGD:6480464
G Lmcd1 LIM and cysteine-rich domains 1 JBrowse link 4 144,192,989 144,252,554 RGD:6480464
G Nqo1 NAD(P)H quinone dehydrogenase 1 JBrowse link 19 38,422,210 38,437,103 RGD:6480464
G Orm1 orosomucoid 1 JBrowse link 5 79,179,668 79,182,820 RGD:6480464
G Por cytochrome p450 oxidoreductase JBrowse link 12 23,998,411 24,017,063 RGD:6480464
G Stat1 signal transducer and activator of transcription 1 JBrowse link 9 54,287,540 54,327,958 RGD:6480464
G Stat3 signal transducer and activator of transcription 3 JBrowse link 10 88,790,401 88,842,263 RGD:6480464
G Tgfb2 transforming growth factor, beta 2 JBrowse link 13 105,039,639 105,142,010 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19728
    role 19675
      biological role 19673
        aetiopathogenetic role 18781
          hepatotoxic agent 14282
            nitrofurantoin 21
Path 2
Term Annotations click to browse term
  CHEBI ontology 19728
    subatomic particle 19724
      composite particle 19724
        hadron 19724
          baryon 19724
            nucleon 19724
              atomic nucleus 19724
                atom 19724
                  main group element atom 19610
                    p-block element atom 19610
                      carbon group element atom 19501
                        carbon atom 19494
                          organic molecular entity 19494
                            organic group 18413
                              organic divalent group 18404
                                organodiyl group 18404
                                  carbonyl group 18293
                                    carbonyl compound 18293
                                      carboxylic acid 17960
                                        carboacyl group 17072
                                          univalent carboacyl group 17072
                                            carbamoyl group 16801
                                              carboxamide 16801
                                                monocarboxylic acid amide 14163
                                                  urea 4949
                                                    ureas 4946
                                                      semicarbazide 40
                                                        nitrofurantoin 21
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.