Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:hydroxyflavonoid
go back to main search page
Accession:CHEBI:71968 term browser browse the term
Definition:Any flavonoid in which one or more ring hydrogens are replaced by hydroxy groups.
Synonyms:related_synonym: hydroxyflavonoids


show annotations for term's descendants           Sort by:
 
6-Hydroxyflavone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pkm pyruvate kinase M1/2 multiple interactions ISO 6-hydroxyflavone inhibits the reaction [PKM protein results in increased metabolism of Phosphoenolpyruvate] CTD PMID:25388478 NCBI chr 8:64,480,963...64,502,957
Ensembl chr 8:64,481,172...64,502,722
JBrowse link
7-hydroxyflavone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1c3 aldo-keto reductase family 1, member C3 decreases activity ISO 7-hydroxyflavone results in decreased activity of AKR1C3 protein CTD PMID:19007764 NCBI chr17:69,761,126...69,778,021
Ensembl chr17:69,761,118...69,778,021
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 decreases activity ISO 7-hydroxyflavone results in decreased activity of CYP19A1 protein CTD PMID:15319488 NCBI chr 8:58,744,849...58,772,408
Ensembl chr 8:58,744,849...58,772,408
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases activity ISO 7-hydroxyflavone results in decreased activity of CYP1A1 protein CTD PMID:21053930 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases activity ISO 7-hydroxyflavone results in decreased activity of CYP1A2 protein CTD PMID:21053930, PMID:29753067 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions ISO 7-hydroxyflavone binds to and results in decreased activity of CYP1B1 protein CTD PMID:21053930 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 decreases activity ISO 7-hydroxyflavone results in decreased activity of CYP2C19 protein CTD PMID:29753067 NCBI chr 1:147,713,879...147,814,410
Ensembl chr 1:147,713,892...147,888,007
JBrowse link
G Pkm pyruvate kinase M1/2 multiple interactions ISO 7-hydroxyflavone inhibits the reaction [PKM protein results in increased metabolism of Phosphoenolpyruvate] CTD PMID:25388478 NCBI chr 8:64,480,963...64,502,957
Ensembl chr 8:64,481,172...64,502,722
JBrowse link
G Slc2a1 solute carrier family 2 member 1 multiple interactions
decreases activity
ISO 7-hydroxyflavone inhibits the reaction [SLC2A1 protein affects the transport of Glucose]
7-hydroxyflavone results in decreased activity of SLC2A1 protein
CTD PMID:14642735 NCBI chr 5:138,154,677...138,182,897
Ensembl chr 5:138,154,673...138,182,897
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19816
    chemical entity 19816
      atom 19814
        nonmetal atom 19690
          oxygen atom 19361
            oxygen molecular entity 19361
              flavonoids 10505
                flavonoid 6376
                  hydroxyflavonoid 8
                    5'-hydroxy-3'-methoxyflavone + 0
                    6-Hydroxyflavone 1
                    7,4'-Dihydroxy-8-methylflavan 0
                    7,4'-Dihydroxyflavan 0
                    7-Hydroxyflavan 0
                    7-hydroxyflavone + 8
                    Apigeninidin 0
                    Aurantinidin 0
                    Favan-3-ol 0
                    Kazinol A 0
                    catechin 5-glucuronide 0
                    diinsinin 0
                    diinsininol 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19816
    subatomic particle 19814
      composite particle 19814
        hadron 19814
          baryon 19814
            nucleon 19814
              atomic nucleus 19814
                atom 19814
                  main group element atom 19702
                    p-block element atom 19702
                      carbon group element atom 19608
                        carbon atom 19597
                          organic molecular entity 19597
                            organic molecule 19522
                              organic cyclic compound 19320
                                organic heterocyclic compound 18432
                                  oxacycle 17200
                                    benzopyran 10142
                                      1-benzopyran 9858
                                        flavonoid 6376
                                          hydroxyflavonoid 8
                                            5'-hydroxy-3'-methoxyflavone + 0
                                            6-Hydroxyflavone 1
                                            7,4'-Dihydroxy-8-methylflavan 0
                                            7,4'-Dihydroxyflavan 0
                                            7-Hydroxyflavan 0
                                            7-hydroxyflavone + 8
                                            Apigeninidin 0
                                            Aurantinidin 0
                                            Favan-3-ol 0
                                            Kazinol A 0
                                            catechin 5-glucuronide 0
                                            diinsinin 0
                                            diinsininol 0
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.