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ONTOLOGY REPORT - ANNOTATIONS


Term:alogliptin
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Accession:CHEBI:72323 term browser browse the term
Definition:A piperidine that is 3-methyl-2,4-dioxo-3,4-dihydropyrimidine carrying additional 2-cyanobenzyl and 3-aminopiperidin-1-yl groups at positions 1 and 2 respectively (the R-enantiomer). Used in the form of its benzoate salt for treatment of type 2 diabetes.
Synonyms:exact_synonym: 2-({6-[(3R)-3-aminopiperidin-1-yl]-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl}methyl)benzonitrile
 related_synonym: Formula=C18H21N5O2;   InChI=1S/C18H21N5O2/c1-21-17(24)9-16(22-8-4-7-15(20)12-22)23(18(21)25)11-14-6-3-2-5-13(14)10-19/h2-3,5-6,9,15H,4,7-8,11-12,20H2,1H3/t15-/m1/s1;   InChIKey=ZSBOMTDTBDDKMP-OAHLLOKOSA-N;   SMILES=Cn1c(=O)cc(N2CCC[C@@H](N)C2)n(Cc2ccccc2C#N)c1=O;   alogliptina;   alogliptine;   alogliptinum
 xref: CAS:850649-61-5 "ChemIDplus";   Drug_Central:4340 "DrugCentral"
 xref_mesh: MESH:C520853
 xref: PMID:20040339 "Europe PMC";   PMID:21205126 "Europe PMC";   PMID:21397040 "Europe PMC";   PMID:21431099 "Europe PMC";   PMID:21558879 "Europe PMC";   PMID:21595274 "Europe PMC";   PMID:21595275 "Europe PMC";   PMID:21682833 "Europe PMC";   PMID:21733058 "Europe PMC";   PMID:21806314 "Europe PMC";   PMID:22106975 "Europe PMC";   PMID:22162539 "Europe PMC";   PMID:22237690 "Europe PMC";   PMID:22249941 "Europe PMC";   PMID:22296609 "Europe PMC";   PMID:22419732 "Europe PMC";   PMID:22429011 "Europe PMC";   PMID:22512582 "Europe PMC";   PMID:22583697 "Europe PMC";   PMID:22651127 "Europe PMC";   PMID:22832924 "Europe PMC";   PMID:23220949 "Europe PMC";   PMID:23289982 "Europe PMC";   PMID:23298374 "Europe PMC";   Patent:EP1970063;   Patent:US2007066635;   Patent:US2009275750;   Patent:WO2008028914;   Patent:WO2009022009;   Patent:WO2010072680;   Reaxys:10587993 "Reaxys";   Wikipedia:Alogliptin
 cyclic_relationship: is_conjugate_base_of CHEBI:72326


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alogliptin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dpp4 dipeptidylpeptidase 4 JBrowse link 3 48,291,055 48,372,672 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19745
    chemical entity 19743
      group 19650
        pseudohalo group 2775
          cyano group 2775
            nitrile 2775
              alogliptin 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19745
    subatomic particle 19741
      composite particle 19741
        hadron 19741
          baryon 19741
            nucleon 19741
              atomic nucleus 19741
                atom 19741
                  main group element atom 19625
                    main group molecular entity 19625
                      s-block molecular entity 19390
                        hydrogen molecular entity 19379
                          hydrides 18293
                            inorganic hydride 17208
                              pnictogen hydride 17170
                                nitrogen hydride 17005
                                  azane 16698
                                    ammonia 16695
                                      organic amino compound 16694
                                        primary amino compound 7786
                                          alogliptin 1
paths to the root

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