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ONTOLOGY REPORT - ANNOTATIONS


Term:hydroxydocosahexaenoic acid
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Accession:CHEBI:72790 term browser browse the term
Definition:A long-chain polyunsaturated fatty acid that is any docosahexaenoic acid bearing a single hydroxy substituent. An oxidation product of docosahexaenoic acid metabolism.
Synonyms:related_synonym: Formula=C22H32O3;   hydroxy DHA;   hydroxydocosahexaenoic acids
 alt_id: CHEBI:139238
 cyclic_relationship: is_conjugate_acid_of CHEBI:131867


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(4Z,7Z,10Z,13Z,15E,19Z)-17-hydroxydocosahexaenoic acid term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Alox5 arachidonate 5-lipoxygenase JBrowse link 4 148,398,004 148,446,308 RGD:6480464
G Ccl2 C-C motif chemokine ligand 2 JBrowse link 10 69,412,065 69,413,863 RGD:6480464
G Cxcl2 C-X-C motif chemokine ligand 2 JBrowse link 14 18,731,346 18,733,391 RGD:6480464
G Cxcl3 C-X-C motif chemokine ligand 3 JBrowse link 14 18,820,168 18,839,659 RGD:6480464
G Icam1 intercellular adhesion molecule 1 JBrowse link 8 22,035,287 22,047,049 RGD:6480464
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:6480464
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:6480464
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:6480464
G Itgal integrin subunit alpha L JBrowse link 1 198,744,053 198,781,745 RGD:6480464
G Mpo myeloperoxidase JBrowse link 10 75,087,892 75,098,260 RGD:6480464
G Nfkbia NFKB inhibitor alpha JBrowse link 6 76,267,227 76,270,457 RGD:6480464
G Pparg peroxisome proliferator-activated receptor gamma JBrowse link 4 147,274,055 147,399,383 RGD:6480464
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:6480464
G Rela RELA proto-oncogene, NF-kB subunit JBrowse link 1 220,992,770 221,003,249 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464
G Vcam1 vascular cell adhesion molecule 1 JBrowse link 2 219,071,193 219,090,931 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19741
    role 19688
      biological role 19686
        biochemical role 19190
          metabolite 19162
            hydroxydocosahexaenoic acid 16
              (4Z,7Z,10Z,13Z,15E,19Z)-17-hydroxydocosahexaenoic acid + 16
              (4Z,7Z,10Z,13Z,16Z,19Z)-22-hydroxydocosahexaenoic acid 0
              (4Z,7Z,10Z,14E,16Z,19Z)-13-hydroxydocosahexaenoic acid 0
              (4Z,8E,10Z,13Z,16Z,19Z)-7-hydroxydocosahexaenoic acid 0
              10-HDoHE 0
              11-HDoHE 0
              14-HDoHE + 0
              16-HDoHE 0
              20-HDoHE 0
              21-HDoHE 0
              4(S)-hydroperoxy-17(R)-hydroxydocosahexaenoic acid 0
              4-HDoHE 0
              4S(5)-epoxy-17R-hydroxydocosahexaenoic acid 0
              7(S)-hydroperoxy-17(R)-hydroxydocosahexaenoic acid 0
              7S,8S-epoxy-17R-hydroxydocosahexaenoic acid 0
              8-HDoHE 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19741
    subatomic particle 19737
      composite particle 19737
        hadron 19737
          baryon 19737
            nucleon 19737
              atomic nucleus 19737
                atom 19737
                  main group element atom 19622
                    p-block element atom 19622
                      carbon group element atom 19515
                        carbon atom 19508
                          organic molecular entity 19508
                            organic group 18423
                              organic divalent group 18414
                                organodiyl group 18414
                                  carbonyl group 18301
                                    carbonyl compound 18301
                                      carboxylic acid 17966
                                        monocarboxylic acid 17265
                                          fatty acid 15813
                                            unsaturated fatty acid 894
                                              polyunsaturated fatty acid 652
                                                fatty acid 22:6 17
                                                  docosahexaenoic acid 17
                                                    hydroxydocosahexaenoic acid 16
                                                      (4Z,7Z,10Z,13Z,15E,19Z)-17-hydroxydocosahexaenoic acid + 16
                                                      (4Z,7Z,10Z,13Z,16Z,19Z)-22-hydroxydocosahexaenoic acid 0
                                                      (4Z,7Z,10Z,14E,16Z,19Z)-13-hydroxydocosahexaenoic acid 0
                                                      (4Z,8E,10Z,13Z,16Z,19Z)-7-hydroxydocosahexaenoic acid 0
                                                      10-HDoHE 0
                                                      11-HDoHE 0
                                                      14-HDoHE + 0
                                                      16-HDoHE 0
                                                      20-HDoHE 0
                                                      21-HDoHE 0
                                                      4(S)-hydroperoxy-17(R)-hydroxydocosahexaenoic acid 0
                                                      4-HDoHE 0
                                                      4S(5)-epoxy-17R-hydroxydocosahexaenoic acid 0
                                                      7(S)-hydroperoxy-17(R)-hydroxydocosahexaenoic acid 0
                                                      7S,8S-epoxy-17R-hydroxydocosahexaenoic acid 0
                                                      8-HDoHE 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.