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Term:oseltamivir acid
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Accession:CHEBI:73139 term browser browse the term
Definition:A cyclohexenecarboxylic acid that is cyclohex-1-ene-1-carboxylic acid which is substituted at positions 3, 4, and 5 by pentan-3-yloxy, acetamido, and amino groups, respectively (the 3R,4R,5S enantiomer). An antiviral drug, it is used as the corresponding ethyl ester prodrug, oseltamivir, to slow the spread of influenza.
Synonyms:exact_synonym: (3R,4R,5S)-4-acetamido-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid
 related_synonym: Formula=C14H24N2O4;   GS 4071;   InChI=1S/C14H24N2O4/c1-4-10(5-2)20-12-7-9(14(18)19)6-11(15)13(12)16-8(3)17/h7,10-13H,4-6,15H2,1-3H3,(H,16,17)(H,18,19)/t11-,12+,13+/m0/s1;   InChIKey=NENPYTRHICXVCS-YNEHKIRRSA-N;   Ro 64-0802;   SMILES=CCC(CC)O[C@@H]1C=C(C[C@H](N)[C@H]1NC(C)=O)C(O)=O;   oseltamivir carboxylate
 xref: CAS:187227-45-8 "ChemIDplus";   PMID:10628898 "Europe PMC";   PMID:21338262 "Europe PMC";   PMID:21495632 "Europe PMC";   PMID:21803598 "Europe PMC";   PMID:22145997 "Europe PMC";   PMID:23000242 "Europe PMC";   PMID:23208436 "Europe PMC";   PMID:23353784 "Europe PMC";   PMID:23362894 "Europe PMC";   PMID:23436258 "Europe PMC";   PMID:23443310 "Europe PMC";   PMID:23459475 "Europe PMC";   PMID:23507284 "Europe PMC";   Reaxys:7714446 "Reaxys"

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  CHEBI ontology 838
    role 815
      biological role 815
        antimicrobial agent 208
          antiviral agent 27
            antiviral drug 21
              oseltamivir acid 0
Path 2
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  CHEBI ontology 838
    subatomic particle 822
      composite particle 822
        hadron 822
          baryon 822
            nucleon 822
              atomic nucleus 822
                atom 822
                  main group element atom 810
                    p-block element atom 807
                      carbon group element atom 778
                        carbon atom 774
                          organic molecular entity 774
                            organic group 358
                              organic divalent group 356
                                organodiyl group 356
                                  carbonyl group 355
                                    carbonyl compound 355
                                      carboxylic acid 242
                                        monocarboxylic acid 131
                                          acetic acid 41
                                            acetate ester 19
                                              oseltamivir acid 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.