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ONTOLOGY REPORT - ANNOTATIONS


Term:3-iodobenzyl-5'-N-methylcarboxamidoadenosine
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Accession:CHEBI:73286 term browser browse the term
Definition:A derivative of adenosine in which the 5'-hydroxymethyl group is replaced by N-ethylcarboxamido and one of the hydrogens of the exocyclic amino function is substituted by a 3-iodobenzyl group.
Synonyms:exact_synonym: (2S,3S,4R,5R)-5-{6-[(3-iodobenzyl)amino]-9H-purin-9-yl}-3,4-dihydroxy-N-methyltetrahydrofuran-2-carboxamide
 related_synonym: 1-Deoxy-1-(6-(((3-iodophenyl)methyl)amino)-9H-purin-9-yl)-N-methyl-beta-D-ribofuranuronamide;   3-IB-Meca;   CF 101;   Formula=C18H19IN6O4;   IB-MECA;   InChI=1S/C18H19IN6O4/c1-20-17(28)14-12(26)13(27)18(29-14)25-8-24-11-15(22-7-23-16(11)25)21-6-9-3-2-4-10(19)5-9/h2-5,7-8,12-14,18,26-27H,6H2,1H3,(H,20,28)(H,21,22,23)/t12-,13+,14-,18+/m0/s1;   InChIKey=HUJXGQILHAUCCV-MOROJQBDSA-N;   N(6)-(3-iodo-benzyl)adenosine-5'-N-methyluronamide;   N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine;   SMILES=CNC(=O)[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(NCc3cccc(I)c3)ncnc12
 xref: CAS:152918-18-8 "ChemIDplus"
 xref_mesh: MESH:C084956
 xref: PMID:23088669 "Europe PMC";   PMID:23098658 "Europe PMC";   PMID:23454010 "Europe PMC";   PMID:23597562 "Europe PMC";   Reaxys:6831623 "Reaxys"


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3-iodobenzyl-5'-N-methylcarboxamidoadenosine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adora3 adenosine A3 receptor JBrowse link 2 208,336,909 208,379,217 RGD:6480464
G Akt1 AKT serine/threonine kinase 1 JBrowse link 6 137,218,398 137,239,970 RGD:6480464
G Birc3 baculoviral IAP repeat-containing 3 JBrowse link 8 6,048,590 6,076,828 RGD:6480464
G Birc5 baculoviral IAP repeat-containing 5 JBrowse link 10 106,856,097 106,864,419 RGD:6480464
G Fos Fos proto-oncogene, AP-1 transcription factor subunit JBrowse link 6 109,300,433 109,303,299 RGD:6480464
G Il12a interleukin 12A JBrowse link 2 165,076,945 165,083,996 RGD:6480464
G Il12b interleukin 12B JBrowse link 10 30,034,447 30,048,774 RGD:6480464
G Naip6 NLR family, apoptosis inhibitory protein 6 JBrowse link 2 30,377,505 30,418,578 RGD:6480464
G Nppa natriuretic peptide A JBrowse link 5 164,808,407 164,809,716 RGD:6480464
G Rgs2 regulator of G-protein signaling 2 JBrowse link 13 60,846,458 60,849,061 RGD:6480464
G Slc9a1 solute carrier family 9 member A1 JBrowse link 5 151,573,122 151,626,360 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19734
    role 19680
      biological role 19678
        pharmacological role 18794
          analgesic 13056
            adenosine 320
              3-iodobenzyl-5'-N-methylcarboxamidoadenosine 11
Path 2
Term Annotations click to browse term
  CHEBI ontology 19734
    subatomic particle 19730
      composite particle 19730
        hadron 19730
          baryon 19730
            nucleon 19730
              atomic nucleus 19730
                atom 19730
                  main group element atom 19614
                    p-block element atom 19614
                      carbon group element atom 19506
                        carbon atom 19500
                          organic molecular entity 19500
                            heteroorganic entity 19066
                              organochalcogen compound 18783
                                organooxygen compound 18696
                                  carbohydrates and carbohydrate derivatives 12112
                                    carbohydrate 12112
                                      carbohydrate derivative 11735
                                        glycosyl compound 10794
                                          N-glycosyl compound 5315
                                            nucleoside 5176
                                              ribonucleoside 681
                                                purine ribonucleoside 576
                                                  purines D-ribonucleoside 327
                                                    adenosine 320
                                                      3-iodobenzyl-5'-N-methylcarboxamidoadenosine 11
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.