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Accession:CHEBI:73378 term browser browse the term
Definition:A member of the class of ergot alkaloids that is known to act on serotonin and dopamine receptors.
Synonyms:exact_synonym: N'-[(8alpha)-1,6-dimethylergolin-8-yl]-N,N-dimethylsulfuric diamide
 related_synonym: Formula=C18H26N4O2S;   InChI=1S/C18H26N4O2S/c1-20(2)25(23,24)19-13-9-15-14-6-5-7-16-18(14)12(10-21(16)3)8-17(15)22(4)11-13/h5-7,10,13,15,17,19H,8-9,11H2,1-4H3/t13-,15+,17+/m0/s1;   InChIKey=JLVHTNZNKOSCNB-YSVLISHTSA-N;   N'-(1,6-Dimethylergolin-8alpha-yl)-N,N-dimethylsulfamide;   SMILES=C1=C2C3=C(C=CC=C3[C@@]4([C@@](C2)(N(C[C@H](C4)NS(N(C)C)(=O)=O)C)[H])[H])N1C;   mesulergina;   mesulerginum
 xref: CAS:64795-35-3;   LINCS:LSM-4045
 xref_mesh: MESH:C031649
 xref: PMID:21190911;   PMID:22313641;   PMID:23597562;   PMID:2895480;   PMID:3428838;   PMID:3708600;   PMID:3881692;   PMID:3895033;   PMID:4067602;   PMID:6230246;   PMID:6386276;   PMID:6488683;   PMID:6527137;   Patent:US4515950;   Reaxys:714438;   Wikipedia:Mesulergine

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mesulergine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Htr2b 5-hydroxytryptamine receptor 2B JBrowse link 9 93,112,781 93,130,135 RGD:6480464
G Htr2c 5-hydroxytryptamine receptor 2C JBrowse link X 118,084,520 118,318,040 RGD:6480464
G Htr7 5-hydroxytryptamine receptor 7 JBrowse link 1 254,547,964 254,671,811 RGD:6480464
G Prl prolactin JBrowse link 17 39,814,236 39,824,299 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19789
    role 19735
      biological role 19734
        pharmacological role 18817
          neurotransmitter agent 16446
            serotonergic drug 3930
              serotonergic antagonist 2231
                mesulergine 4
Path 2
Term Annotations click to browse term
  CHEBI ontology 19789
    subatomic particle 19787
      composite particle 19787
        hadron 19787
          baryon 19787
            nucleon 19787
              atomic nucleus 19787
                atom 19787
                  main group element atom 19672
                    main group molecular entity 19672
                      s-block molecular entity 19415
                        hydrogen molecular entity 19405
                          hydrides 18376
                            inorganic hydride 17224
                              pnictogen hydride 17187
                                nitrogen hydride 17021
                                  azane 16716
                                    ammonia 16715
                                      organic amino compound 16714
                                        polyamine 8112
                                          diamine 8039
                                            ergoline 17
                                              mesulergine 4
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.