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Term:18-carboxy-19,20-dinor-leukotriene E4
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Accession:CHEBI:74017 term browser browse the term
Definition:An icosanoid that is leukotriene E4 in which two methylene groups are removed from the carboxyalkyl chain attached to the non-conjugated double bond.
Synonyms:exact_synonym: (4Z,7Z,9E,11E,13R,14S)-13-(L-cystein-S-yl)-14-hydroxyoctadeca-4,7,9,11-tetraenedioic acid;   (4Z,7Z,9E,11E,13R,14S)-13-{[(2R)-2-amino-2-carboxyethyl]sulfanyl}-14-hydroxyoctadeca-4,7,9,11-tetraenedioic acid
 related_synonym: 18-carboxy-19,20-dinor-LTE4;   18-carboxy-dinor-LTE4;   18-carboxy-dinor-leukotriene E4;   Formula=C21H31NO7S;   InChI=1S/C21H31NO7S/c22-16(21(28)29)15-30-18(17(23)11-10-14-20(26)27)12-8-6-4-2-1-3-5-7-9-13-19(24)25/h1-2,4-8,12,16-18,23H,3,9-11,13-15,22H2,(H,24,25)(H,26,27)(H,28,29)/b2-1-,6-4+,7-5-,12-8+/t16-,17-,18+/m0/s1;   InChIKey=OXCSBZDIZXLXRX-AVYHYKEVSA-N;   SMILES=[H][C@](N)(CS[C@H](\\C=C\\C=C\\C=C/C\\C=C/CCC(O)=O)[C@@H](O)CCCC(O)=O)C(O)=O
 xref: HMDB:HMDB0012607;   PMID:2174886 "Europe PMC";   PMID:7663693 "Europe PMC";   PMID:8484009 "Europe PMC";   Reaxys:4588801 "Reaxys"

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  CHEBI ontology 0
    role 0
      biological role 0
        biochemical role 0
          metabolite 0
            18-carboxy-19,20-dinor-leukotriene E4 0
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  CHEBI ontology 0
    subatomic particle 0
      composite particle 0
        hadron 0
          baryon 0
            nucleon 0
              atomic nucleus 0
                atom 0
                  main group element atom 0
                    p-block element atom 0
                      carbon group element atom 0
                        carbon atom 0
                          organic molecular entity 0
                            organic group 0
                              organic divalent group 0
                                organodiyl group 0
                                  carbonyl group 0
                                    carbonyl compound 0
                                      carboxylic acid 0
                                        amino acid 0
                                          alpha-amino acid 0
                                            L-alpha-amino acid 0
                                              serine family amino acid 0
                                                L-cysteine 0
                                                  L-cysteine derivative 0
                                                    S-substituted L-cysteine 0
                                                      L-cysteine thioether 0
                                                        leukotriene E4 0
                                                          18-carboxy-19,20-dinor-leukotriene E4 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.