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Term:losartan carboxylic acid
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Accession:CHEBI:74125 term browser browse the term
Definition:A biphenylyltetrazole that is losartan with the hydroxymethyl group at position 5 on the imidazole ring replaced with a carboxylic acid.
Synonyms:exact_synonym: 2-butyl-4-chloro-1-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-imidazole-5-carboxylic acid
 related_synonym: EXP 3174;   Formula=C22H21ClN6O2;   InChI=1S/C22H21ClN6O2/c1-2-3-8-18-24-20(23)19(22(30)31)29(18)13-14-9-11-15(12-10-14)16-6-4-5-7-17(16)21-25-27-28-26-21/h4-7,9-12H,2-3,8,13H2,1H3,(H,30,31)(H,25,26,27,28);   InChIKey=ZEUXAIYYDDCIRX-UHFFFAOYSA-N;   SMILES=CCCCc1nc(Cl)c(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1
 xref: CAS:124750-92-1 "ChemIDplus";   CAS:124750-92-1 "KEGG COMPOUND";   KEGG:C15554
 xref_mesh: MESH:C066026
 xref: Reaxys:6164851 "Reaxys"

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losartan carboxylic acid term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Slc22a25 solute carrier family 22, member 25 JBrowse link 1 224,596,886 224,698,512 RGD:6480464

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Path 1
Term Annotations click to browse term
  CHEBI ontology 19728
    role 19675
      biological role 19673
        biochemical role 19178
          metabolite 19150
            losartan carboxylic acid 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19728
    subatomic particle 19724
      composite particle 19724
        hadron 19724
          baryon 19724
            nucleon 19724
              atomic nucleus 19724
                atom 19724
                  main group element atom 19610
                    p-block element atom 19610
                      carbon group element atom 19501
                        carbon atom 19494
                          organic molecular entity 19494
                            organic molecule 19417
                              organic cyclic compound 19184
                                organic heterocyclic compound 18262
                                  heteroarene 15814
                                    monocyclic heteroarene 13126
                                      azole 12255
                                        diazole 8078
                                          imidazoles 7631
                                            losartan 160
                                              losartan carboxylic acid 1
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.