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ONTOLOGY REPORT - ANNOTATIONS


Term:nadolol
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Accession:CHEBI:7444 term browser browse the term
Definition:Nadolol is a diastereoisomeric mixture consisting of equimolar amounts of the four possible 2,3-cis-isomers of 5-[3-(tert-butylamino)-2-hydroxypropoxy]-1,2,3,4-tetrahydronaphthalene-2,3-diol.
Synonyms:exact_synonym: rac-(2R,3S)-5-[3-(tert-butylamino)-2-hydroxypropoxy]-1,2,3,4-tetrahydronaphthalene-2,3-diol
 related_synonym: 1-(tert-butylamino)-3-[(5,6,7,8-tetrahydro-cis-6,7-dihydroxy-1-naphthyl)oxy]-2-propanol;   2,3-cis-1,2,3,4-tetrahydro-5-((2-hydroxy-3-tert-butylamino)propoxy)-2,3-naphthalenediol;   Corgard;   Solgol
 xref: Beilstein:2508986 "Beilstein";   CAS:42200-33-9 "ChemIDplus";   CAS:42200-33-9 "NIST Chemistry WebBook";   DrugBank:DB01203;   KEGG:D00432;   LINCS:LSM-1879
 xref_mesh: MESH:D009248
 xref: Patent:DE2258995;   Patent:DE2421549;   Patent:US3935267


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nadolol term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adrb1 adrenoceptor beta 1 JBrowse link 1 277,537,585 277,538,985 RGD:6480464
G Adrb2 adrenoceptor beta 2 JBrowse link 18 57,513,792 57,515,834 RGD:6480464
G Il10 interleukin 10 JBrowse link 13 47,738,933 47,743,392 RGD:6480464
G Il12b interleukin 12B JBrowse link 10 30,034,447 30,048,774 RGD:6480464
G Slc22a1 solute carrier family 22 member 1 JBrowse link 1 48,273,639 48,300,645 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19749
    chemical entity 19747
      chemical substance 11493
        mixture 10811
          diastereoisomeric mixture 420
            nadolol 5
Path 2
Term Annotations click to browse term
  CHEBI ontology 19749
    subatomic particle 19745
      composite particle 19745
        hadron 19745
          baryon 19745
            nucleon 19745
              atomic nucleus 19745
                atom 19745
                  main group element atom 19630
                    main group molecular entity 19630
                      s-block molecular entity 19390
                        hydrogen molecular entity 19379
                          hydrides 18296
                            inorganic hydride 17209
                              pnictogen hydride 17171
                                nitrogen hydride 17006
                                  azane 16699
                                    ammonia 16696
                                      organic amino compound 16695
                                        secondary amino compound 6377
                                          (2R,3S,2'R)-nadolol 5
                                            nadolol 5
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.