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ONTOLOGY REPORT - ANNOTATIONS


Term:nafcillin
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Accession:CHEBI:7447 term browser browse the term
Definition:A penicillin in which the substituent at position 6 of the penam ring is a (2-ethoxy-1-naphthoyl)amino group.
Synonyms:exact_synonym: 6beta-(2-ethoxynaphthalene-1-carboxamido)-2,2-dimethylpenam-3alpha-carboxylic acid
 related_synonym: (2-ethoxy-1-naphthalenyl)penicillin;   (2-ethoxy-1-naphthyl)penicillin;   (2S,5R,6R)-6-[(2-ethoxy-1-naphthoyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid;   (2S,5R,6R)-6-[(2-ethoxynaphthalene-1-carbonyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid;   (2S,5R,6R)-6-{[(2-ethoxynaphthalen-1-yl)carbonyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid;   6-(2-ethoxy-1-naphthamido)penicillanic acid;   Formula=C21H22N2O5S;   InChI=1S/C21H22N2O5S/c1-4-28-13-10-9-11-7-5-6-8-12(11)14(13)17(24)22-15-18(25)23-16(20(26)27)21(2,3)29-19(15)23/h5-10,15-16,19H,4H2,1-3H3,(H,22,24)(H,26,27)/t15-,16+,19-/m1/s1;   InChIKey=GPXLMGHLHQJAGZ-JTDSTZFVSA-N;   SMILES=[H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)c1c(OCC)ccc2ccccc12)C(O)=O;   nafcilina;   nafcilline;   nafcillinum;   naphcillin
 alt_id: CHEBI:44256
 xref: Beilstein:5405727 "Beilstein";   CAS:147-52-4 "ChemIDplus";   CAS:147-52-4 "KEGG COMPOUND";   DrugBank:DB00607;   Drug_Central:1869 "DrugCentral";   KEGG:C07250;   KEGG:D08242;   LINCS:LSM-2402
 xref_mesh: MESH:D009254
 xref: PMID:29017833 "Europe PMC";   Patent:GB880400;   Patent:US3157639;   Patent:US3506645;   Reaxys:5405727 "Reaxys";   Wikipedia:Nafcillin
 cyclic_relationship: is_conjugate_acid_of CHEBI:51918


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nafcillin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 JBrowse link 11 65,022,100 65,058,546 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19728
    role 19675
      biological role 19673
        aetiopathogenetic role 18781
          allergen 16858
            penicillin 259
              nafcillin 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19728
    subatomic particle 19724
      composite particle 19724
        hadron 19724
          baryon 19724
            nucleon 19724
              atomic nucleus 19724
                atom 19724
                  main group element atom 19610
                    p-block element atom 19610
                      carbon group element atom 19501
                        carbon atom 19494
                          organic molecular entity 19494
                            organic group 18413
                              organic divalent group 18404
                                organodiyl group 18404
                                  carbonyl group 18293
                                    carbonyl compound 18293
                                      carboxylic acid 17960
                                        carboacyl group 17072
                                          univalent carboacyl group 17072
                                            carbamoyl group 16801
                                              carboxamide 16801
                                                lactam 7814
                                                  beta-lactam 784
                                                    beta-lactam antibiotic 772
                                                      penams 259
                                                        penicillanic acids 259
                                                          penicillanic acid 259
                                                            6-aminopenicillanic acid 259
                                                              penicillin 259
                                                                penicillin allergen 256
                                                                  nafcillin 1
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