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Accession:CHEBI:7451 term browser browse the term
Definition:A tertiary amine in which the nitrogen is substituted by methyl, alpha-naphthylmethyl, and (1E)-cinnamyl groups. It is used (usually as its hydrochloride salt) for the treatment of fungal skin infections.
Synonyms:exact_synonym: (2E)-N-methyl-N-(1-naphthylmethyl)-3-phenylprop-2-en-1-amine
 related_synonym: (E)-N-cinnamyl-N-methyl-1-naphthalenemethylamine;   Formula=C21H21N;   InChI=1S/C21H21N/c1-22(16-8-11-18-9-3-2-4-10-18)17-20-14-7-13-19-12-5-6-15-21(19)20/h2-15H,16-17H2,1H3/b11-8+;   InChIKey=OZGNYLLQHRPOBR-DHZHZOJOSA-N;   SMILES=CN(C\\C=C\\c1ccccc1)Cc1cccc2ccccc12;   naftifin;   naftifina;   naftifinum;   trans-N-cinnamyl-N-methyl-(1-naphthylmethyl)amine
 xref: CAS:65472-88-0 "ChemIDplus";   CAS:65472-88-0 "KEGG COMPOUND";   DrugBank:DB00735;   Drug_Central:1872 "DrugCentral";   HMDB:HMDB0014873;   KEGG:C08071;   KEGG:D08245
 xref_mesh: MESH:C029178
 xref: PMID:18212112 "Europe PMC";   PMID:24196340 "Europe PMC";   PMID:25294700 "Europe PMC";   PMID:6388170 "Europe PMC";   Patent:BE853976;   Patent:US4282251;   Reaxys:2983617 "Reaxys";   Wikipedia:Naftifine

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naftifine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Kcnh2 potassium voltage-gated channel subfamily H member 2 JBrowse link 4 7,355,066 7,387,282 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19734
    role 19680
      biological role 19678
        inhibitor 18160
          sterol biosynthesis inhibitor 2897
            naftifine 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19734
    subatomic particle 19730
      composite particle 19730
        hadron 19730
          baryon 19730
            nucleon 19730
              atomic nucleus 19730
                atom 19730
                  main group element atom 19614
                    main group molecular entity 19614
                      s-block molecular entity 19378
                        hydrogen molecular entity 19367
                          hydrides 18289
                            inorganic hydride 17210
                              pnictogen hydride 17172
                                nitrogen hydride 17008
                                  azane 16699
                                    ammonia 16696
                                      organic amino compound 16695
                                        tertiary amino compound 8558
                                          tertiary amine 603
                                            naftifine 1
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.