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ONTOLOGY REPORT - ANNOTATIONS


Term:9-aminoacridine
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Accession:CHEBI:74789 term browser browse the term
Definition:An aminoacridine that is acridine in which the hydrogen at position 9 is replaced by an amino group. A fluorescent dyd and topical antiseptic agent, it is used (usually as the hydrochloride salt) in eye drops for the treatment of superficial eye infections.
Synonyms:exact_synonym: acridin-9-amine
 related_synonym: 10-amino-5-azaanthracene;   5-aminoacridine;   9-acridinamine;   9AA;   Formula=C13H10N2;   InChI=1S/C13H10N2/c14-13-9-5-1-3-7-11(9)15-12-8-4-2-6-10(12)13/h1-8H,(H2,14,15);   InChIKey=XJGFWWJLMVZSIG-UHFFFAOYSA-N;   SMILES=Nc1c2ccccc2nc2ccccc12;   aminacrin;   aminacrine;   aminoacridina;   aminoacridine;   aminoacridinum
 xref: CAS:90-45-9 "ChemIDplus";   CAS:90-45-9 "NIST Chemistry WebBook";   Drug_Central:160 "DrugCentral";   LINCS:LSM-15516
 xref_mesh: MESH:D000585
 xref: PMID:22477060 "Europe PMC";   PMID:23257326 "Europe PMC";   PMID:24341665 "Europe PMC";   Reaxys:141171 "Reaxys";   Wikipedia:9-Aminoacridine
 cyclic_relationship: is_conjugate_base_of CHEBI:74835


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9-aminoacridine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ache acetylcholinesterase JBrowse link 12 22,472,358 22,477,052 RGD:6480464
G Bax BCL2 associated X, apoptosis regulator JBrowse link 1 101,451,801 101,457,207 RGD:6480464
G H2ax H2A.X variant histone JBrowse link 8 48,665,652 48,666,981 RGD:6480464
G Hif1a hypoxia inducible factor 1 subunit alpha JBrowse link 6 96,810,868 96,856,303 RGD:6480464
G Mdc1 mediator of DNA damage checkpoint 1 JBrowse link 20 3,405,017 3,419,831 RGD:6480464
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 JBrowse link 7 30,003,429 30,162,095 RGD:6480464
G Slc22a2 solute carrier family 22 member 2 JBrowse link 1 48,318,025 48,360,219 RGD:6480464
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:6480464

Term paths to the root
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Term Annotations click to browse term
  CHEBI ontology 19741
    role 19688
      application 19339
        MALDI matrix material 911
          9-aminoacridine 8
Path 2
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  CHEBI ontology 19741
    subatomic particle 19737
      composite particle 19737
        hadron 19737
          baryon 19737
            nucleon 19737
              atomic nucleus 19737
                atom 19737
                  main group element atom 19622
                    p-block element atom 19622
                      carbon group element atom 19515
                        carbon atom 19508
                          organic molecular entity 19508
                            organic molecule 19431
                              organic cyclic compound 19197
                                organic heterocyclic compound 18267
                                  organic heteropolycyclic compound 17574
                                    organic heterotricyclic compound 13723
                                      dibenzopyridine 145
                                        acridines 112
                                          aminoacridines 17
                                            9-aminoacridine 8
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.