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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:netilmycin
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Accession:CHEBI:7528 term browser browse the term
Definition:A beta-L-arabinoside that has formula C21H41N5O7.
Synonyms:exact_synonym: (1S,2S,3R,4S,6R)-4-amino-3-[(2S,3R)-3-amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-yloxy]-6-(ethylamino)-2-hydroxycyclohexyl 3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranoside
 related_synonym: 1-N-Ethylsisomicin;   Formula=C21H41N5O7;   InChI=1S/C21H41N5O7/c1-4-26-13-7-12(24)16(32-19-11(23)6-5-10(8-22)31-19)15(28)17(13)33-20-21(2,29)18(25-3)14(27)9-30-20/h5,11-20,25-29H,4,6-9,22-24H2,1-3H3/t11-,12+,13-,14+,15+,16-,17+,18-,19-,20-,21-/m1/s1;   InChIKey=ZBGPYVZLYBDXKO-HILBYHGXSA-N;   Netilmicin;   O-3-Deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranosyl-(1-6)-O-(2,6-diamino-2,3,4,6-tetradeoxy-alpha-D-glycero-hex-4-enopyranosyl-(1-4))-2-deoxy-N(1)-ethyl-D-streptamine;   SMILES=CCN[C@@H]1C[C@H](N)[C@@H](O[C@H]2OC(CN)=CC[C@H]2N)[C@H](O)[C@H]1O[C@H]1OC[C@H](O)[C@@H](NC)[C@@]1(C)O
 xref: CAS:56391-56-1;   DrugBank:DB00955;   KEGG:C07657;   KEGG:D08268
 xref_mesh: MESH:D009428


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netilmycin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pgd phosphogluconate dehydrogenase decreases activity ISO Netilmicin results in decreased activity of PGD protein CTD PMID:15558954 NCBI chr 4:149,149,991...149,166,705
Ensembl chr 4:149,149,991...149,166,771
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 21450
    role 21426
      biological role 21424
        antimicrobial agent 18257
          carbohydrate-containing antibiotic 2545
            aminoglycoside antibiotic 2526
              netilmycin 1
                netilmicin sulfate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 21450
    subatomic particle 21434
      composite particle 21434
        hadron 21434
          baryon 21434
            nucleon 21434
              atomic nucleus 21434
                atom 21434
                  main group element atom 21329
                    p-block element atom 21329
                      carbon group element atom 21100
                        carbon atom 20999
                          organic molecular entity 20999
                            heteroorganic entity 20696
                              organochalcogen compound 19902
                                organooxygen compound 19828
                                  carbohydrates and carbohydrate derivatives 12753
                                    carbohydrate 12753
                                      carbohydrate derivative 12378
                                        glycosyl compound 11083
                                          glycoside 9383
                                            pentoside 576
                                              arabinoside 574
                                                beta-L-arabinoside 1
                                                  netilmycin 1
                                                    netilmicin sulfate 0
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