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ONTOLOGY REPORT - ANNOTATIONS


Term:tyrphostin AG 825
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Accession:CHEBI:75405 term browser browse the term
Definition:An organic sulfide that consists of 1,3-benzothiazole-2-thiol in which the hydrogen attached to the sulfur atom is replaced by a 5-[(1E)-3-amino-2-cyano-3-oxoprop-1-en-1-yl]-2-hydroxy-3-methoxybenzyl group. It acts as an epidermal growth factor receptor antagonist.
Synonyms:exact_synonym: (2E)-3-{3-[(1,3-benzothiazol-2-ylsulfanyl)methyl]-4-hydroxy-5-methoxyphenyl}-2-cyanoprop-2-enamide
 related_synonym: Formula=C19H15N3O3S2;   InChI=1S/C19H15N3O3S2/c1-25-15-8-11(6-12(9-20)18(21)24)7-13(17(15)23)10-26-19-22-14-4-2-3-5-16(14)27-19/h2-8,23H,10H2,1H3,(H2,21,24)/b12-6+;   InChIKey=KXDONFLNGBQLTN-WUXMJOGZSA-N;   SMILES=C(=C/C=1C=C(CSC2=NC=3C=CC=CC3S2)C(=C(C1)OC)O)(\\C(=O)N)/C#N
 xref: PMID:20049896 "Europe PMC";   PMID:9735325 "Europe PMC";   Reaxys:14612999 "Reaxys"


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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19764
    chemical entity 19763
      group 19672
        pseudohalo group 2774
          cyano group 2774
            nitrile 2774
              tyrphostin AG 825 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19764
    subatomic particle 19762
      composite particle 19762
        hadron 19762
          baryon 19762
            nucleon 19762
              atomic nucleus 19762
                atom 19762
                  main group element atom 19646
                    p-block element atom 19646
                      carbon group element atom 19540
                        carbon atom 19529
                          organic molecular entity 19529
                            organic group 18432
                              organic divalent group 18423
                                organodiyl group 18423
                                  carbonyl group 18311
                                    carbonyl compound 18311
                                      carboxylic acid 17976
                                        carboacyl group 17082
                                          univalent carboacyl group 17082
                                            carbamoyl group 16810
                                              carboxamide 16810
                                                alpha,beta-unsaturated carboxylic acid amide 4754
                                                  enamide 4754
                                                    tyrphostin AG 825 0
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