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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:2-(4-chloro-2-methylphenoxy)propanoic acid
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Accession:CHEBI:75704 term browser browse the term
Definition:A monocarboxylic acid that is lactic acid in which the hydroxyl hydrogen is replaced by a 4-chloro-2-methylphenyl group.
Synonyms:related_synonym: 2-(4-Chloro-2-tolyloxy)propionic acid;   2-(4-chloro-2-methylphenoxy)propionic acid;   2-(p-Chloro-o-tolyloxy)propionic acid;   4-Chloro-2-methylphenoxy-alpha-propionic acid;   Formula=C10H11ClO3;   InChI=1S/C10H11ClO3/c1-6-5-8(11)3-4-9(6)14-7(2)10(12)13/h3-5,7H,1-2H3,(H,12,13);   InChIKey=WNTGYJSOUMFZEP-UHFFFAOYSA-N;   Mecoprop;   O-(4-chloro-2-methylphenyl)lactic acid;   SMILES=CC(Oc1ccc(Cl)cc1C)C(O)=O
 xref: CAS:93-65-2;   KEGG:C18742
 xref_mesh: MESH:C008340
 xref: Reaxys:2212752;   Wikipedia:Mecoprop


show annotations for term's descendants           Sort by:
 
2-(4-chloro-2-methylphenoxy)propanoic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crat carnitine O-acetyltransferase increases activity ISO mecoprop results in increased activity of CRAT protein CTD PMID:1755024 NCBI chr 3:8,967,984...8,981,959
Ensembl chr 3:8,968,417...8,981,362
JBrowse link
G Ephx2 epoxide hydrolase 2 increases activity ISO mecoprop results in increased activity of EPHX2 protein CTD PMID:1755024 NCBI chr15:42,757,241...42,794,211
Ensembl chr15:42,757,235...42,794,279
JBrowse link
G Ifng interferon gamma decreases expression ISO mecoprop results in decreased expression of IFNG protein CTD PMID:10883730 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Tnf tumor necrosis factor decreases expression ISO mecoprop results in decreased expression of TNF protein CTD PMID:10883730 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
mecoprop term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crat carnitine O-acetyltransferase increases activity ISO mecoprop results in increased activity of CRAT protein CTD PMID:1755024 NCBI chr 3:8,967,984...8,981,959
Ensembl chr 3:8,968,417...8,981,362
JBrowse link
G Ephx2 epoxide hydrolase 2 increases activity ISO mecoprop results in increased activity of EPHX2 protein CTD PMID:1755024 NCBI chr15:42,757,241...42,794,211
Ensembl chr15:42,757,235...42,794,279
JBrowse link
G Ifng interferon gamma decreases expression ISO mecoprop results in decreased expression of IFNG protein CTD PMID:10883730 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Tnf tumor necrosis factor decreases expression ISO mecoprop results in decreased expression of TNF protein CTD PMID:10883730 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19816
    chemical entity 19816
      chemical substance 11959
        mixture 10880
          racemate 9777
            rac-lactic acid 2789
              2-(4-chloro-2-methylphenoxy)propanoic acid 4
                (R)-mecoprop + 4
                (S)-mecoprop + 4
Path 2
Term Annotations click to browse term
  CHEBI ontology 19816
    subatomic particle 19814
      composite particle 19814
        hadron 19814
          baryon 19814
            nucleon 19814
              atomic nucleus 19814
                atom 19814
                  main group element atom 19702
                    p-block element atom 19702
                      carbon group element atom 19608
                        carbon atom 19597
                          organic molecular entity 19597
                            organic group 18537
                              organic divalent group 18530
                                organodiyl group 18530
                                  carbonyl group 18436
                                    carbonyl compound 18436
                                      carboxylic acid 18114
                                        monocarboxylic acid 17476
                                          fatty acid 15990
                                            saturated fatty acid 15965
                                              propionic acid 3670
                                                2-hydroxypropanoic acid 2789
                                                  (R)-lactic acid 2789
                                                    rac-lactic acid 2789
                                                      2-(4-chloro-2-methylphenoxy)propanoic acid 4
                                                        (R)-mecoprop + 4
                                                        (S)-mecoprop + 4
paths to the root

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