Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   


go back to main search page
Accession:CHEBI:75922 term browser browse the term
Definition:A monocarboxylic acid amide that is amfenac in which the carboxylic acid group has been converted to the corresponding carboxamide. It is a prodrug for amfenac, used in eye drops to treat pain and inflammation following cataract surgery.
Synonyms:exact_synonym: 2-(2-amino-3-benzoylphenyl)acetamide
 related_synonym: 2-amino-3-benzoylbenzeneacetamide;   AHR-9434;   AL 6515;   Formula=C15H14N2O2;   InChI=1S/C15H14N2O2/c16-13(18)9-11-7-4-8-12(14(11)17)15(19)10-5-2-1-3-6-10/h1-8H,9,17H2,(H2,16,18);   InChIKey=QEFAQIPZVLVERP-UHFFFAOYSA-N;   Nevanac;   SMILES=NC(=O)Cc1cccc(C(=O)c2ccccc2)c1N;   nepafenaco;   nepafenacum
 xref: CAS:78281-72-8 "ChemIDplus";   DrugBank:DB06802;   Drug_Central:1899 "DrugCentral";   HMDB:HMDB0015678;   KEGG:D05143;   PMID:10850857 "Europe PMC";   PMID:10850858 "Europe PMC";   PMID:16466612 "Europe PMC";   PMID:16529348 "Europe PMC";   PMID:17060788 "Europe PMC";   PMID:20674259 "Europe PMC";   PMID:21926942 "Europe PMC";   PMID:21932014 "Europe PMC";   PMID:22927737 "Europe PMC";   PMID:23715071 "Europe PMC";   PMID:23928675 "Europe PMC";   Reaxys:4256257 "Reaxys";   Wikipedia:Nepafenac

show annotations for term's descendants       view all columns           Sort by:

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19734
    role 19680
      application 19336
        pro-agent 8821
          prodrug 8610
            nepafenac 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19734
    subatomic particle 19730
      composite particle 19730
        hadron 19730
          baryon 19730
            nucleon 19730
              atomic nucleus 19730
                atom 19730
                  main group element atom 19614
                    p-block element atom 19614
                      carbon group element atom 19506
                        carbon atom 19500
                          organic molecular entity 19500
                            organic group 18414
                              organic divalent group 18406
                                organodiyl group 18406
                                  carbonyl group 18295
                                    carbonyl compound 18295
                                      carboxylic acid 17963
                                        carboacyl group 17074
                                          univalent carboacyl group 17074
                                            carbamoyl group 16804
                                              carboxamide 16804
                                                monocarboxylic acid amide 14167
                                                  nepafenac 0
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.