Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:3-tert-butyl-4-hydroxyanisole
go back to main search page
Accession:CHEBI:76358 term browser browse the term
Definition:An aromatic ether that is 4-methoxyphenol in which one of the hydrogens ortho- to the phenolic hydroxy group is replaced by a tert-butyl group.
Synonyms:exact_synonym: 2-tert-butyl-4-methoxyphenol
 related_synonym: 2-(1,1-dimethylethyl)-4-methoxyphenol;   3-(1,1-dimethylethyl)-4-hydroxyanisole;   3-BHA;   3-tert-butyl-p-hydroxyanisole;   4-hydroxy-3-tert-butylanisole;   4-methoxy-2-tert-butylphenol;   4-methoxy-6-tert-butylphenol;   Formula=C11H16O2;   InChI=1S/C11H16O2/c1-11(2,3)9-7-8(13-4)5-6-10(9)12/h5-7,12H,1-4H3;   InChIKey=MRBKEAMVRSLQPH-UHFFFAOYSA-N;   SMILES=COc1ccc(O)c(c1)C(C)(C)C;   o-tert-butyl-p-methoxyphenol;   p-methoxy-o-tert-butylphenol
 xref: CAS:121-00-6;   CAS:921-00-6;   HMDB:HMDB0031848
 xref_mesh: MESH:C051362
 xref: PMID:3201475;   PMID:4053035;   PMID:6542057;   PMID:7388831;   Reaxys:1867499


show annotations for term's descendants           Sort by:
 
3-tert-butyl-4-hydroxyanisole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mt1 metallothionein 1 increases expression ISO 3-tert-butyl-4-hydroxyanisole results in increased expression of MT1 mRNA CTD PMID:14998373 NCBI chr19:11,301,991...11,303,007
Ensembl chr17:78,793,336...78,793,724
JBrowse link
butylated hydroxyanisole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc2 ATP binding cassette subfamily C member 2 multiple interactions
increases expression
ISO [Butylated Hydroxyanisole results in increased activity of NFE2L2 protein] which results in increased expression of ABCC2 mRNA
Butylated Hydroxyanisole results in increased expression of ABCC2 mRNA; Butylated Hydroxyanisole results in increased expression of ABCC2 protein
CTD PMID:15833929, PMID:16426233 NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 multiple interactions
increases expression
ISO [Butylated Hydroxyanisole results in increased activity of NFE2L2 protein] which results in increased expression of ABCC3 mRNA
Butylated Hydroxyanisole results in increased expression of ABCC3 mRNA
CTD PMID:15833929 NCBI chr10:82,047,308...82,116,928
Ensembl chr10:82,047,863...82,117,109
JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 increases expression
multiple interactions
ISO Butylated Hydroxyanisole results in increased expression of ABCC4 mRNA
[Butylated Hydroxyanisole results in increased activity of NFE2L2 protein] which results in increased expression of ABCC4 mRNA
CTD PMID:15833929 NCBI chr15:103,695,415...103,927,980
Ensembl chr15:103,696,557...103,927,592
JBrowse link
G Abcc5 ATP binding cassette subfamily C member 5 multiple interactions
increases expression
ISO [Butylated Hydroxyanisole results in increased activity of NFE2L2 protein] which results in increased expression of ABCC5 mRNA
Butylated Hydroxyanisole results in increased expression of ABCC5 mRNA
CTD PMID:15833929 NCBI chr11:84,395,982...84,490,215
Ensembl chr11:84,396,033...84,490,211
JBrowse link
G Abcc6 ATP binding cassette subfamily C member 6 multiple interactions
increases expression
ISO [Butylated Hydroxyanisole results in increased activity of NFE2L2 protein] which results in increased expression of ABCC6 mRNA
Butylated Hydroxyanisole results in increased expression of ABCC6 mRNA
CTD PMID:15833929 NCBI chr 1:101,954,786...102,013,252
Ensembl chr 1:101,959,540...102,013,243
JBrowse link
G Aco1 aconitase 1 multiple interactions EXP Butylated Hydroxyanisole inhibits the reaction [Cadmium Chloride affects the localization of ACO1 protein] CTD PMID:25106854 NCBI chr 5:56,425,076...56,481,218
Ensembl chr 5:56,425,024...56,481,218
JBrowse link
G Ahr aryl hydrocarbon receptor increases expression ISO Butylated Hydroxyanisole results in increased expression of AHR mRNA CTD PMID:17627975 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Akr7a3 aldo-keto reductase family 7 member A3 increases expression EXP Butylated Hydroxyanisole results in increased expression of AKR7A3 protein CTD PMID:8198522 NCBI chr 5:157,801,120...157,813,756
Ensembl chr 5:157,801,163...157,813,756
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 increases expression ISO Butylated Hydroxyanisole results in increased expression of ALDH1A1 mRNA CTD PMID:17998271 NCBI chr 1:238,222,689...238,264,381
Ensembl chr 1:238,222,521...238,264,330
JBrowse link
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 decreases expression ISO Butylated Hydroxyanisole results in decreased expression of ALDH1A2 mRNA CTD PMID:28927898 NCBI chr 8:77,640,234...77,719,488
Ensembl chr 8:77,640,222...77,719,489
JBrowse link
G Aldh1b1 aldehyde dehydrogenase 1 family, member B1 increases expression ISO Butylated Hydroxyanisole results in increased expression of ALDH1B1 mRNA CTD PMID:17998271 NCBI chr 5:61,382,351...61,387,359
Ensembl chr 5:61,382,351...61,387,358
JBrowse link
G Aldh3a1 aldehyde dehydrogenase 3 family, member A1 increases expression ISO Butylated Hydroxyanisole results in increased expression of ALDH3A1 mRNA CTD PMID:17998271 NCBI chr10:47,490,168...47,499,855
Ensembl chr10:47,490,153...47,499,876
JBrowse link
G Aldh4a1 aldehyde dehydrogenase 4 family, member A1 increases expression ISO Butylated Hydroxyanisole results in increased expression of ALDH4A1 mRNA CTD PMID:17998271 NCBI chr 5:158,090,238...158,115,725
Ensembl chr 5:158,042,587...158,135,733
JBrowse link
G Aldh7a1 aldehyde dehydrogenase 7 family, member A1 increases expression ISO Butylated Hydroxyanisole results in increased expression of ALDH7A1 mRNA CTD PMID:17998271 NCBI chr18:51,619,007...51,651,267
Ensembl chr18:51,619,007...51,651,267
JBrowse link
G Aldh8a1 aldehyde dehydrogenase 8 family, member A1 increases expression ISO Butylated Hydroxyanisole results in increased expression of ALDH8A1 mRNA CTD PMID:17998271 NCBI chr 1:16,910,043...16,929,465
Ensembl chr 1:16,910,069...16,930,481
JBrowse link
G Ar androgen receptor affects binding
multiple interactions
ISO Butylated Hydroxyanisole binds to AR protein
Butylated Hydroxyanisole inhibits the reaction [Dihydrotestosterone binds to and results in increased activity of AR protein]; Butylated Hydroxyanisole inhibits the reaction [Dihydrotestosterone binds to AR protein]
CTD PMID:10696776, PMID:14579009 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Atp6v1a ATPase H+ transporting V1 subunit A multiple interactions ISO Butylated Hydroxyanisole inhibits the reaction [TNF protein results in decreased expression of ATP6V1A protein]
Butylated Hydroxyanisole inhibits the reaction [Reactive Oxygen Species results in decreased expression of ATP6V1A protein]
CTD PMID:12470298 NCBI chr11:61,531,386...61,584,634
Ensembl chr11:61,531,416...61,584,634
JBrowse link
G Aurkb aurora kinase B increases expression EXP Butylated Hydroxyanisole results in increased expression of AURKB protein CTD PMID:23535288 NCBI chr10:55,625,860...55,632,399
Ensembl chr10:55,626,741...55,634,991
JBrowse link
G Ca13 carbonic anhydrase 13 increases expression ISO Butylated Hydroxyanisole results in increased expression of CAR13 mRNA CTD PMID:19000923 NCBI chr 2:88,282,961...88,314,254
Ensembl chr 2:88,282,961...88,314,254
JBrowse link
G Car1 carbonic anhydrase 1 decreases activity ISO Butylated Hydroxyanisole results in decreased activity of CA1 protein CTD PMID:19231207 NCBI chr 2:88,185,204...88,227,486
Ensembl chr 2:88,217,188...88,227,479
JBrowse link
G Car2 carbonic anhydrase 2 decreases activity ISO Butylated Hydroxyanisole results in decreased activity of CA2 protein CTD PMID:19231207 NCBI chr 2:88,097,740...88,112,868
Ensembl chr 2:88,097,720...88,113,029
JBrowse link
G Casp3 caspase 3 multiple interactions
decreases activity
ISO [Butylated Hydroxyanisole co-treated with Butylated Hydroxytoluene] results in decreased activity of CASP3 protein; Butylated Hydroxyanisole inhibits the reaction [ellipticine results in increased cleavage of and results in increased activity of CASP3 protein]; Butylated Hydroxyanisole inhibits the reaction [Fenretinide results in increased activity of CASP3 protein]
Butylated Hydroxyanisole results in decreased activity of CASP3 protein
CTD PMID:14981915, PMID:16407847, PMID:21843585 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp7 caspase 7 multiple interactions ISO Butylated Hydroxyanisole inhibits the reaction [ellipticine results in increased cleavage of and results in increased activity of CASP7 protein] CTD PMID:21843585 NCBI chr 1:277,190,557...277,242,779
Ensembl chr 1:277,190,964...277,242,774
JBrowse link
G Cat catalase multiple interactions EXP Butylated Hydroxyanisole inhibits the reaction [Estradiol results in increased activity of CAT protein]; Butylated Hydroxyanisole inhibits the reaction [tetrabromobisphenol A results in decreased activity of CAT protein] CTD PMID:19526586, PMID:27718046 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cbr1 carbonyl reductase 1 increases expression ISO Butylated Hydroxyanisole results in increased expression of CBR1 mRNA; Butylated Hydroxyanisole results in increased expression of CBR1 protein CTD PMID:23247010 NCBI chr11:33,813,041...33,815,418
Ensembl chr11:33,845,463...33,847,793
JBrowse link
G Cbx5 chromobox 5 increases expression EXP Butylated Hydroxyanisole results in increased expression of CBX5 protein CTD PMID:23535288 NCBI chr 7:144,819,673...144,865,014
Ensembl chr 7:144,819,420...144,837,583
JBrowse link
G Ccnb1 cyclin B1 increases expression ISO Butylated Hydroxyanisole results in increased expression of CCNB1 mRNA CTD PMID:19000923 NCBI chr 2:30,782,133...30,791,106
Ensembl chr 2:30,783,915...30,791,221
JBrowse link
G Cdk1 cyclin-dependent kinase 1 increases expression EXP Butylated Hydroxyanisole results in increased expression of CDK1 protein CTD PMID:23535288 NCBI chr20:20,576,341...20,591,510
Ensembl chr20:20,576,377...20,591,549
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression
multiple interactions
ISO Butylated Hydroxyanisole results in increased expression of CDKN1A mRNA
Hydrogen Peroxide promotes the reaction [Butylated Hydroxyanisole results in increased expression of CDKN1A mRNA]
CTD PMID:29486183 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdx1 caudal type homeo box 1 affects expression ISO Butylated Hydroxyanisole affects the expression of CDX1 mRNA CTD PMID:28927898 NCBI chr18:56,337,485...56,355,477
Ensembl chr18:56,338,336...56,355,490
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta multiple interactions ISO Butylated Hydroxyanisole inhibits the reaction [LHB protein results in increased abundance of CEBPB mRNA] CTD PMID:21220312 NCBI chr 3:164,424,502...164,425,933
Ensembl chr 3:164,424,515...164,425,910
JBrowse link
G Ces1d carboxylesterase 1D increases expression
decreases expression
ISO Butylated Hydroxyanisole results in increased expression of CES1 mRNA
Butylated Hydroxyanisole results in decreased expression of CES1D protein
CTD PMID:18227147, PMID:26179144 NCBI chr19:15,195,514...15,239,827
Ensembl chr19:15,033,108...15,239,821
JBrowse link
G Ces2c carboxylesterase 2C decreases expression ISO Butylated Hydroxyanisole results in decreased expression of CES2C protein CTD PMID:26179144 NCBI chr 1:282,640,752...282,648,319
Ensembl chr 1:282,638,017...282,702,424
JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions ISO CTNNB1 gene mutant form inhibits the reaction [Butylated Hydroxyanisole results in increased expression of CYP1A1 mRNA]; CTNNB1 gene mutant form inhibits the reaction [Butylated Hydroxyanisole results in increased expression of CYP1A2 mRNA] CTD PMID:25174530 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression
multiple interactions
ISO Butylated Hydroxyanisole results in increased expression of CYP1A1 mRNA
CTNNB1 gene mutant form inhibits the reaction [Butylated Hydroxyanisole results in increased expression of CYP1A1 mRNA]
CTD PMID:25174530 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression
multiple interactions
ISO Butylated Hydroxyanisole results in increased expression of CYP1A2 mRNA
CTNNB1 gene mutant form inhibits the reaction [Butylated Hydroxyanisole results in increased expression of CYP1A2 mRNA]
CTD PMID:25174530 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 increases expression ISO Butylated Hydroxyanisole results in increased expression of CYP2B10 mRNA CTD PMID:17627975 NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783
JBrowse link
G Cyp2j4 cytochrome P450, family 2, subfamily j, polypeptide 4 increases expression ISO Butylated Hydroxyanisole results in increased expression of CYP2J2 mRNA CTD PMID:24021950 NCBI chr 5:119,546,458...119,564,843
Ensembl chr 5:119,546,461...119,564,846
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions ISO Butylated Hydroxyanisole inhibits the reaction [MAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased expression of DDIT3 mRNA]] CTD PMID:18691550 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Dmp1 dentin matrix acidic phosphoprotein 1 increases expression ISO Butylated Hydroxyanisole results in increased expression of DMP1 mRNA CTD PMID:19000923 NCBI chr14:6,889,851...6,923,961
Ensembl chr14:6,889,856...6,900,733
JBrowse link
G Dusp1 dual specificity phosphatase 1 affects response to substance
multiple interactions
ISO DUSP1 protein affects the susceptibility to Butylated Hydroxyanisole
DUSP1 protein affects the reaction [Butylated Hydroxyanisole affects the reaction [Dextran Sulfate affects the expression of IL6 protein]]; DUSP1 protein affects the reaction [Butylated Hydroxyanisole affects the reaction [Dextran Sulfate affects the expression of TNF protein]]; DUSP1 protein affects the reaction [Butylated Hydroxyanisole inhibits the reaction [Dextran Sulfate results in increased expression of PTGS2 protein]]
CTD PMID:30844440 NCBI chr10:16,970,642...16,973,425
Ensembl chr10:16,970,626...16,973,418
JBrowse link
G Egfr epidermal growth factor receptor multiple interactions ISO Butylated Hydroxyanisole inhibits the reaction [LHB protein results in increased phosphorylation of and results in increased activity of EGFR protein]
Butylated Hydroxyanisole inhibits the reaction [Particulate Matter results in increased phosphorylation of EGFR protein]; Butylated Hydroxyanisole inhibits the reaction [Vehicle Emissions results in increased phosphorylation of EGFR protein]
CTD PMID:17028263, PMID:21220312 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
JBrowse link
G Ephx1 epoxide hydrolase 1 increases activity ISO Butylated Hydroxyanisole results in increased activity of EPHX1 protein CTD PMID:3621371 NCBI chr13:99,271,390...99,300,580
Ensembl chr13:99,271,366...99,300,579
JBrowse link
G Ephx2 epoxide hydrolase 2 decreases expression
increases activity
ISO Butylated Hydroxyanisole results in decreased expression of EPHX2 protein
Butylated Hydroxyanisole results in increased activity of EPHX2 protein
CTD PMID:3621371 NCBI chr15:42,757,241...42,794,211
Ensembl chr15:42,757,235...42,794,279
JBrowse link
G Esr1 estrogen receptor 1 affects binding
multiple interactions
decreases expression
increases activity
ISO Butylated Hydroxyanisole binds to ESR1 protein
Butylated Hydroxyanisole inhibits the reaction [Estradiol binds to ESR1 protein]
Butylated Hydroxyanisole results in decreased expression of ESR1 mRNA
Butylated Hydroxyanisole results in increased activity of ESR1 protein
CTD PMID:12822488, PMID:14579009, PMID:16756374, PMID:19063592 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Esr2 estrogen receptor 2 affects binding
multiple interactions
increases activity
ISO Butylated Hydroxyanisole binds to ESR2 protein
Butylated Hydroxyanisole inhibits the reaction [Estradiol binds to ESR2 protein]
Butylated Hydroxyanisole results in increased activity of ESR2 protein
CTD PMID:12822488, PMID:16756374 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO Butylated Hydroxyanisole promotes the reaction [FOS protein binds to NQO1 promoter] CTD PMID:8375015 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit increases expression ISO Butylated Hydroxyanisole results in increased expression of FOSL1 mRNA CTD PMID:19000923 NCBI chr 1:220,826,560...220,835,066
Ensembl chr 1:220,826,560...220,835,066
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression ISO Butylated Hydroxyanisole results in increased expression of GCLC mRNA
Butylated Hydroxyanisole results in increased expression of GCLC mRNA; Butylated Hydroxyanisole results in increased expression of GCLC protein
CTD PMID:16426233, PMID:25922074 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Gsta2 glutathione S-transferase alpha 2 increases expression ISO
EXP
Butylated Hydroxyanisole results in increased expression of GSTA1 mRNA; Butylated Hydroxyanisole results in increased expression of GSTA1 protein; Butylated Hydroxyanisole results in increased expression of GSTA2 mRNA; Butylated Hydroxyanisole results in increased expression of GSTA2 protein
Butylated Hydroxyanisole results in increased expression of GSTA3 protein
CTD PMID:1859377, PMID:2049074, PMID:2597111, PMID:9794803, PMID:11309284, PMID:11991805, PMID:16426233, PMID:29086419 NCBI chr 8:85,640,081...85,645,621 JBrowse link
G Gsta3 glutathione S-transferase alpha 3 increases expression ISO Butylated Hydroxyanisole results in increased expression of GSTA3 protein CTD PMID:11309284 NCBI chr 9:27,357,490...27,417,023
Ensembl chr 9:27,402,381...27,417,023
JBrowse link
G Gsta5 glutathione S-transferase alpha 5 multiple interactions
increases expression
EXP Butylated Hydroxyanisole promotes the reaction [GSTA5 protein affects the metabolism of aflatoxin B1-2,3-oxide]; Butylated Hydroxyanisole results in increased expression of and results in increased activity of GSTA5 protein
Butylated Hydroxyanisole results in increased expression of GSTA5 protein
CTD PMID:8198522, PMID:9794803 NCBI chr 8:85,553,659...85,564,914
Ensembl chr 8:85,553,734...85,565,179
JBrowse link
G Gsta6 glutathione S-transferase alpha 6 increases expression ISO Butylated Hydroxyanisole results in increased expression of GSTA1 mRNA; Butylated Hydroxyanisole results in increased expression of GSTA1 protein; Butylated Hydroxyanisole results in increased expression of GSTA2 mRNA; Butylated Hydroxyanisole results in increased expression of GSTA2 protein CTD PMID:1859377, PMID:2049074, PMID:2597111, PMID:11309284, PMID:11991805, PMID:16426233, PMID:29086419 NCBI chr 9:27,475,273...27,533,939
Ensembl chr 9:27,475,273...27,511,176
JBrowse link
G Gstm1 glutathione S-transferase mu 1 multiple interactions
increases expression
increases activity
ISO NFE2L2 protein affects the reaction [Butylated Hydroxyanisole results in increased activity of GSTM1 protein]
Butylated Hydroxyanisole results in increased expression of GSTM1 mRNA; Butylated Hydroxyanisole results in increased expression of GSTM1 protein
CTD PMID:2597111, PMID:11309284, PMID:11895860, PMID:11991805, PMID:18723825, PMID:29086419 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G Gstm2 glutathione S-transferase mu 2 increases expression ISO Butylated Hydroxyanisole results in increased expression of GSTM2 mRNA; Butylated Hydroxyanisole results in increased expression of GSTM2 protein CTD PMID:1859377, PMID:11991805, PMID:18723825 NCBI chr 2:210,778,041...210,782,807
Ensembl chr 2:210,720,704...210,782,856
JBrowse link
G Gstm4 glutathione S-transferase mu 4 increases expression ISO Butylated Hydroxyanisole results in increased expression of GSTM4 mRNA; Butylated Hydroxyanisole results in increased expression of GSTM4 protein CTD PMID:1859377, PMID:11991805, PMID:18723825 NCBI chr 2:210,834,013...210,839,242
Ensembl chr 2:210,833,884...210,839,295
JBrowse link
G Gstm5 glutathione S-transferase, mu 5 increases expression ISO
EXP
Butylated Hydroxyanisole results in increased expression of GSTM3 mRNA; Butylated Hydroxyanisole results in increased expression of GSTM3 protein; Butylated Hydroxyanisole results in increased expression of GSTM5 protein CTD PMID:6822548, PMID:9794803, PMID:11309284, PMID:11991805, PMID:18723825 NCBI chr 2:210,685,338...210,688,133
Ensembl chr 2:210,685,197...210,688,272
JBrowse link
G Gsto1 glutathione S-transferase omega 1 increases expression ISO Butylated Hydroxyanisole results in increased expression of GSTO1 mRNA CTD PMID:18723825 NCBI chr 1:267,607,437...267,617,387
Ensembl chr 1:267,607,418...267,617,387
JBrowse link
G Gstp1 glutathione S-transferase pi 1 increases activity
increases expression
multiple interactions
ISO
EXP
Butylated Hydroxyanisole results in increased activity of GSTP1 protein
Butylated Hydroxyanisole results in increased expression of GSTP1 protein
NFE2L2 protein affects the reaction [Butylated Hydroxyanisole results in increased activity of GSTP1 protein]; NFE2L2 protein affects the reaction [Butylated Hydroxyanisole results in increased expression of GSTP1 protein]
CTD PMID:2597111, PMID:9794803, PMID:11895860 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G Gstt1 glutathione S-transferase theta 1 increases expression EXP Butylated Hydroxyanisole results in increased expression of GSTT1 mRNA; Butylated Hydroxyanisole results in increased expression of GSTT1 protein CTD PMID:9794803 NCBI chr20:13,799,102...13,816,527
Ensembl chr20:13,799,102...13,816,526
JBrowse link
G Has2 hyaluronan synthase 2 multiple interactions ISO Butylated Hydroxyanisole inhibits the reaction [LHB protein results in increased abundance of HAS2 mRNA] CTD PMID:21220312 NCBI chr 7:96,438,046...96,464,049
Ensembl chr 7:96,438,046...96,464,049
JBrowse link
G Hells helicase, lymphoid specific increases expression ISO Butylated Hydroxyanisole results in increased expression of HELLS mRNA CTD PMID:19000923 NCBI chr 1:257,901,856...257,953,889
Ensembl chr 1:257,766,691...257,949,183
Ensembl chr 1:257,766,691...257,949,183
JBrowse link
G Hexb hexosaminidase subunit beta multiple interactions EXP zinc chloride inhibits the reaction [Butylated Hydroxyanisole results in increased secretion of HEXB protein] CTD PMID:15272608 NCBI chr 2:27,983,925...28,003,260
Ensembl chr 2:27,984,117...28,003,186
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression
ISO 1-aminobenzotriazole inhibits the reaction [[Butylated Hydroxyanisole co-treated with Buthionine Sulfoximine] results in increased expression of HMOX1 mRNA]; [Hydrogen Peroxide co-treated with Butylated Hydroxyanisole] results in increased expression of HMOX1 mRNA; Buthionine Sulfoximine promotes the reaction [Butylated Hydroxyanisole results in increased expression of HMOX1 mRNA]
Butylated Hydroxyanisole results in increased expression of HMOX1 mRNA; Butylated Hydroxyanisole results in increased expression of HMOX1 protein
CTD PMID:18227147, PMID:25922074, PMID:29086419, PMID:29486183 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hoxa1 homeobox A1 decreases expression ISO Butylated Hydroxyanisole results in decreased expression of HOXA1 mRNA CTD PMID:28927898 NCBI chr 4:82,124,358...82,127,182
Ensembl chr 4:82,125,406...82,127,066
JBrowse link
G Hoxb9 homeo box B9 decreases expression ISO Butylated Hydroxyanisole results in decreased expression of HOXB9 mRNA CTD PMID:28927898 NCBI chr10:84,119,772...84,124,963
Ensembl chr10:84,119,884...84,123,390
JBrowse link
G Ifng interferon gamma multiple interactions ISO Butylated Hydroxyanisole results in decreased expression of and results in decreased secretion of IFNG protein CTD PMID:22250088 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta multiple interactions ISO Butylated Hydroxyanisole inhibits the reaction [IKBKB protein inhibits the reaction [Diethylnitrosamine results in increased activity of MAPK8 protein]]; Butylated Hydroxyanisole inhibits the reaction [IKBKB protein inhibits the reaction [Diethylnitrosamine results in increased expression of IL1A protein]]; Butylated Hydroxyanisole inhibits the reaction [IKBKB protein inhibits the reaction [Diethylnitrosamine results in increased expression of IL6 protein]] CTD PMID:18691550 NCBI chr16:74,177,233...74,230,809
Ensembl chr16:74,177,215...74,230,815
JBrowse link
G Il1a interleukin 1 alpha multiple interactions ISO Butylated Hydroxyanisole inhibits the reaction [IKBKB protein inhibits the reaction [Diethylnitrosamine results in increased expression of IL1A protein]]; Butylated Hydroxyanisole inhibits the reaction [MAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased expression of IL1A protein]] CTD PMID:18691550 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO Butylated Hydroxyanisole inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]
Butylated Hydroxyanisole inhibits the reaction [IL1B protein results in increased abundance of Dinoprostone]
CTD PMID:1515551, PMID:8186192 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il1rl1 interleukin 1 receptor-like 1 increases expression ISO Butylated Hydroxyanisole results in increased expression of IL1RL1 mRNA CTD PMID:19000923 NCBI chr 9:47,133,483...47,184,316
Ensembl chr 9:47,134,034...47,182,170
JBrowse link
G Il6 interleukin 6 multiple interactions ISO Butylated Hydroxyanisole affects the reaction [Dextran Sulfate affects the expression of IL6 protein]; Butylated Hydroxyanisole inhibits the reaction [IKBKB protein inhibits the reaction [Diethylnitrosamine results in increased expression of IL6 protein]]; Butylated Hydroxyanisole inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; Butylated Hydroxyanisole inhibits the reaction [MAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased expression of IL6 protein]]; DUSP1 protein affects the reaction [Butylated Hydroxyanisole affects the reaction [Dextran Sulfate affects the expression of IL6 protein]]; NFE2L2 protein affects the reaction [Butylated Hydroxyanisole affects the reaction [Dextran Sulfate affects the expression of IL6 protein]] CTD PMID:8186192, PMID:18691550, PMID:30844440 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions
ISO Butylated Hydroxyanisole results in increased expression of JUN mRNA
Butylated Hydroxyanisole promotes the reaction [JUN protein binds to NQO1 promoter]
CTD PMID:8375015, PMID:19000923 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Lfng LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase decreases expression ISO Butylated Hydroxyanisole results in decreased expression of LFNG mRNA CTD PMID:28927898 NCBI chr12:16,117,767...16,126,211
Ensembl chr12:16,118,634...16,126,953
JBrowse link
G Lhb luteinizing hormone subunit beta multiple interactions ISO Butylated Hydroxyanisole inhibits the reaction [LHB protein results in increased abundance of CEBPB mRNA]; Butylated Hydroxyanisole inhibits the reaction [LHB protein results in increased abundance of HAS2 mRNA]; Butylated Hydroxyanisole inhibits the reaction [LHB protein results in increased abundance of PGR mRNA]; Butylated Hydroxyanisole inhibits the reaction [LHB protein results in increased abundance of PTGS2 mRNA]; Butylated Hydroxyanisole inhibits the reaction [LHB protein results in increased abundance of TNFAIP6 mRNA]; Butylated Hydroxyanisole inhibits the reaction [LHB protein results in increased phosphorylation of and results in increased activity of EGFR protein]; Butylated Hydroxyanisole inhibits the reaction [LHB protein results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Butylated Hydroxyanisole inhibits the reaction [LHB protein results in increased phosphorylation of and results in increased activity of MAPK3 protein] CTD PMID:21220312 NCBI chr 1:101,409,992...101,413,725
Ensembl chr 1:101,410,019...101,413,724
JBrowse link
G Lhx1 LIM homeobox 1 decreases expression ISO Butylated Hydroxyanisole results in decreased expression of LHX1 mRNA CTD PMID:28927898 NCBI chr10:71,843,991...71,849,293
Ensembl chr10:71,843,991...71,849,293
JBrowse link
G Map2k4 mitogen activated protein kinase kinase 4 multiple interactions ISO Butylated Hydroxyanisole inhibits the reaction [Fenretinide results in increased phosphorylation of MAP2K4 protein] CTD PMID:16407847 NCBI chr10:52,196,121...52,301,887
Ensembl chr10:52,196,124...52,290,657
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO Butylated Hydroxyanisole inhibits the reaction [ellipticine results in increased phosphorylation of MAPK1 protein]; Butylated Hydroxyanisole inhibits the reaction [Fenretinide results in increased phosphorylation of MAPK1 protein]
Butylated Hydroxyanisole inhibits the reaction [LHB protein results in increased phosphorylation of and results in increased activity of MAPK1 protein]
CTD PMID:16407847, PMID:21220312, PMID:21843585 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk14 mitogen activated protein kinase 14 multiple interactions ISO Butylated Hydroxyanisole inhibits the reaction [MAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased activity of MAPK8 protein]]; Butylated Hydroxyanisole inhibits the reaction [MAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased expression of DDIT3 mRNA]]; Butylated Hydroxyanisole inhibits the reaction [MAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased expression of IL1A protein]]; Butylated Hydroxyanisole inhibits the reaction [MAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased expression of IL6 protein]] CTD PMID:18691550 NCBI chr20:5,933,290...5,995,137
Ensembl chr20:5,933,303...5,995,137
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO Butylated Hydroxyanisole inhibits the reaction [ellipticine results in increased phosphorylation of MAPK3 protein]; Butylated Hydroxyanisole inhibits the reaction [Fenretinide results in increased phosphorylation of MAPK3 protein]
Butylated Hydroxyanisole inhibits the reaction [LHB protein results in increased phosphorylation of and results in increased activity of MAPK3 protein]
CTD PMID:16407847, PMID:21220312, PMID:21843585 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO
EXP
Butylated Hydroxyanisole inhibits the reaction [Fenretinide results in increased phosphorylation of MAPK8 protein]
Butylated Hydroxyanisole inhibits the reaction [Methylnitrosourea results in increased activity of MAPK8 protein]
Butylated Hydroxyanisole inhibits the reaction [Diethylnitrosamine results in increased activity of MAPK8 protein]; Butylated Hydroxyanisole inhibits the reaction [IKBKB protein inhibits the reaction [Diethylnitrosamine results in increased activity of MAPK8 protein]]; Butylated Hydroxyanisole inhibits the reaction [MAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased activity of MAPK8 protein]]; Butylated Hydroxyanisole inhibits the reaction [Methylnitrosourea results in increased activity of MAPK8 protein]
CTD PMID:15989949, PMID:16407847, PMID:18593901, PMID:18691550 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Meox1 mesenchyme homeobox 1 decreases expression ISO Butylated Hydroxyanisole results in decreased expression of MEOX1 mRNA CTD PMID:28927898 NCBI chr10:89,797,011...89,817,009
Ensembl chr10:89,797,038...89,816,491
JBrowse link
G Mgst3 microsomal glutathione S-transferase 3 increases expression ISO Butylated Hydroxyanisole results in increased expression of MGST3 mRNA CTD PMID:18723825 NCBI chr13:85,601,499...85,622,392
Ensembl chr13:85,601,499...85,622,314
JBrowse link
G Mixl1 Mix paired-like homeobox 1 decreases expression ISO Butylated Hydroxyanisole results in decreased expression of MIXL1 mRNA CTD PMID:28927898 NCBI chr13:97,278,258...97,282,299
Ensembl chr13:98,973,041...98,975,426
Ensembl chr13:98,973,041...98,975,426
JBrowse link
G Mki67 marker of proliferation Ki-67 increases expression
decreases expression
EXP Butylated Hydroxyanisole results in increased expression of MKI67 protein
Butylated Hydroxyanisole results in decreased expression of MKI67 protein
CTD PMID:23535288 NCBI chr 1:207,993,895...208,020,454
Ensembl chr 1:207,993,895...208,020,454
JBrowse link
G Mt-co2 mitochondrially encoded cytochrome c oxidase II multiple interactions ISO Butylated Hydroxyanisole inhibits the reaction [Reactive Oxygen Species results in decreased expression of COX2 protein]
Butylated Hydroxyanisole inhibits the reaction [TNF protein results in decreased expression of COX2 protein]
CTD PMID:12470298 NCBI chr MT:7,006...7,689
Ensembl chr MT:7,006...7,689
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 affects activity
affects response to substance
multiple interactions
increases expression
ISO
EXP
Butylated Hydroxyanisole affects the activity of NFE2L2 protein
NFE2L2 protein affects the susceptibility to Butylated Hydroxyanisole
Butylated Hydroxyanisole results in increased stability of and results in increased expression of NFE2L2 protein
Butylated Hydroxyanisole results in increased expression of NFE2L2 protein
Butylated Hydroxyanisole inhibits the reaction [Estradiol inhibits the reaction [NFE2L2 protein binds to SOD3 promoter]]
[Butylated Hydroxyanisole results in increased activity of NFE2L2 protein] which results in increased expression of ABCC2 mRNA; [Butylated Hydroxyanisole results in increased activity of NFE2L2 protein] which results in increased expression of ABCC3 mRNA; [Butylated Hydroxyanisole results in increased activity of NFE2L2 protein] which results in increased expression of ABCC4 mRNA; [Butylated Hydroxyanisole results in increased activity of NFE2L2 protein] which results in increased expression of ABCC5 mRNA; [Butylated Hydroxyanisole results in increased activity of NFE2L2 protein] which results in increased expression of ABCC6 mRNA; Butylated Hydroxyanisole binds to and results in increased activity of NFE2L2 protein; NFE2L2 protein affects the reaction [Butylated Hydroxyanisole affects the reaction [Dextran Sulfate affects the expression of IL6 protein]]; NFE2L2 protein affects the reaction [Butylated Hydroxyanisole affects the reaction [Dextran Sulfate affects the expression of TNF protein]]; NFE2L2 protein affects the reaction [Butylated Hydroxyanisole inhibits the reaction [Dextran Sulfate results in increased expression of PTGS2 protein]]; NFE2L2 protein affects the reaction [Butylated Hydroxyanisole results in increased activity of GSTM1 protein]; NFE2L2 protein affects the reaction [Butylated Hydroxyanisole results in increased activity of GSTP1 protein]; NFE2L2 protein affects the reaction [Butylated Hydroxyanisole results in increased expression of GSTP1 protein]
CTD PMID:11309284, PMID:11895860, PMID:15833929, PMID:15919853, PMID:22530035, PMID:23027624, PMID:30844440 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases activity
multiple interactions
increases expression
ISO
EXP
Butylated Hydroxyanisole results in increased activity of NQO1 protein
Butylated Hydroxyanisole promotes the reaction [FOS protein binds to NQO1 promoter]; Butylated Hydroxyanisole promotes the reaction [JUN protein binds to NQO1 promoter]
Butylated Hydroxyanisole results in increased expression of NQO1 mRNA; Butylated Hydroxyanisole results in increased expression of NQO1 protein
CTD PMID:8375015, PMID:10092053, PMID:11309284, PMID:15919853, PMID:16045903, PMID:16403784, PMID:17627975, PMID:18227147, PMID:19144771, PMID:25922074, PMID:29086419 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases expression ISO Butylated Hydroxyanisole results in increased expression of NR1I2 mRNA CTD PMID:17627975 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases expression ISO Butylated Hydroxyanisole results in increased expression of NR1I3 mRNA CTD PMID:17627975 NCBI chr13:89,585,072...89,591,278
Ensembl chr13:89,586,283...89,591,277
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO Butylated Hydroxyanisole inhibits the reaction [Fenretinide results in increased cleavage of PARP1 protein] CTD PMID:16407847 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Pgr progesterone receptor affects binding
increases expression
multiple interactions
ISO Butylated Hydroxyanisole binds to PGR protein
Butylated Hydroxyanisole results in increased expression of PGR mRNA
Butylated Hydroxyanisole inhibits the reaction [LHB protein results in increased abundance of PGR mRNA]
Butylated Hydroxyanisole inhibits the reaction [Progesterone binds to PGR protein]
CTD PMID:12822488, PMID:14579009, PMID:21220312 NCBI chr 8:7,128,656...7,187,796
Ensembl chr 8:7,128,656...7,187,796
JBrowse link
G Phex phosphate regulating endopeptidase homolog, X-linked increases expression ISO Butylated Hydroxyanisole results in increased expression of PHEX mRNA CTD PMID:19000923 NCBI chr  X:40,460,047...40,717,982
Ensembl chr  X:40,460,047...40,717,982
JBrowse link
G Pik3r5 phosphoinositide-3-kinase, regulatory subunit 5 increases expression ISO Butylated Hydroxyanisole results in increased expression of PIK3R5 mRNA CTD PMID:19000923 NCBI chr10:55,013,686...55,078,986
Ensembl chr10:55,013,703...55,080,421
JBrowse link
G Prkcd protein kinase C, delta multiple interactions ISO Butylated Hydroxyanisole inhibits the reaction [Ursodeoxycholic Acid results in increased localization of PRKCD protein] CTD PMID:21362627 NCBI chr16:6,655,131...6,675,746
Ensembl chr16:6,655,120...6,675,746
JBrowse link
G Psmc6 proteasome 26S subunit, ATPase 6 multiple interactions ISO Butylated Hydroxyanisole inhibits the reaction [Reactive Oxygen Species results in decreased expression of PSMC6 mRNA]
Butylated Hydroxyanisole inhibits the reaction [TNF protein results in decreased expression of PSMC6 mRNA]
CTD PMID:12470298 NCBI chr15:19,667,453...19,688,916
Ensembl chr15:19,667,453...19,688,914
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO Butylated Hydroxyanisole inhibits the reaction [Dextran Sulfate results in increased expression of PTGS2 protein]; Butylated Hydroxyanisole inhibits the reaction [LHB protein results in increased abundance of PTGS2 mRNA]; DUSP1 protein affects the reaction [Butylated Hydroxyanisole inhibits the reaction [Dextran Sulfate results in increased expression of PTGS2 protein]]; NFE2L2 protein affects the reaction [Butylated Hydroxyanisole inhibits the reaction [Dextran Sulfate results in increased expression of PTGS2 protein]] CTD PMID:21220312, PMID:30844440 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Rad51ap1 RAD51 associated protein 1 increases expression ISO Butylated Hydroxyanisole results in increased expression of RAD51AP1 mRNA CTD PMID:19000923 NCBI chr 4:159,469,803...159,482,869
Ensembl chr 4:159,469,804...159,482,869
JBrowse link
G Sesn2 sestrin 2 multiple interactions ISO Butylated Hydroxyanisole inhibits the reaction [erastin results in increased expression of SESN2 protein] CTD PMID:31323261 NCBI chr 5:150,684,891...150,703,846
Ensembl chr 5:150,684,133...150,704,117
JBrowse link
G Slc2a1 solute carrier family 2 member 1 increases expression ISO Butylated Hydroxyanisole results in increased expression of SLC2A1 mRNA CTD PMID:19000923 NCBI chr 5:138,154,677...138,182,897
Ensembl chr 5:138,154,673...138,182,897
JBrowse link
G Slco2b1 solute carrier organic anion transporter family, member 2b1 increases expression ISO Butylated Hydroxyanisole results in increased expression of SLCO2B1 mRNA CTD PMID:15919853 NCBI chr 1:164,623,313...164,671,612
Ensembl chr 1:164,623,599...164,671,577
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions ISO [Butylated Hydroxyanisole co-treated with Butylated Hydroxytoluene] results in decreased expression of SOD2 mRNA CTD PMID:14981915 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Sod3 superoxide dismutase 3 multiple interactions
increases activity
increases expression
EXP Butylated Hydroxyanisole inhibits the reaction [Estradiol inhibits the reaction [NFE2L2 protein binds to SOD3 promoter]]; Butylated Hydroxyanisole inhibits the reaction [Estradiol results in decreased activity of SOD3 protein]; Butylated Hydroxyanisole inhibits the reaction [Estradiol results in decreased expression of SOD3 mRNA]; Butylated Hydroxyanisole inhibits the reaction [Estradiol results in decreased expression of SOD3 protein]
Butylated Hydroxyanisole results in increased activity of SOD3 protein
Butylated Hydroxyanisole results in increased expression of SOD3 mRNA; Butylated Hydroxyanisole results in increased expression of SOD3 protein
CTD PMID:23027624 NCBI chr14:60,958,583...60,971,143
Ensembl chr14:60,958,592...60,964,324
JBrowse link
G Sp5 Sp5 transcription factor decreases expression ISO Butylated Hydroxyanisole results in decreased expression of SP5 mRNA CTD PMID:28927898 NCBI chr 3:56,766,475...56,769,277
Ensembl chr 3:56,766,475...56,769,277
JBrowse link
G Srxn1 sulfiredoxin 1 increases expression ISO Butylated Hydroxyanisole results in increased expression of SRXN1 protein CTD PMID:27358234 NCBI chr 3:147,608,850...147,614,410
Ensembl chr 3:147,609,095...147,632,801
JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO Butylated Hydroxyanisole inhibits the reaction [Particulate Matter results in increased phosphorylation of STAT3 protein]; Butylated Hydroxyanisole inhibits the reaction [Vanadates results in increased phosphorylation of STAT3 protein]; Butylated Hydroxyanisole inhibits the reaction [Vehicle Emissions results in increased phosphorylation of STAT3 protein] CTD PMID:17028263 NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233
JBrowse link
G Sult1e1 sulfotransferase family 1E member 1 increases expression ISO Butylated Hydroxyanisole results in increased expression of SULT1E1 mRNA CTD PMID:25922074 NCBI chr14:22,070,861...22,089,264
Ensembl chr14:22,072,024...22,089,248
JBrowse link
G Tbx6 T-box transcription factor 6 decreases expression ISO Butylated Hydroxyanisole results in decreased expression of TBX6 mRNA CTD PMID:28927898 NCBI chr 1:198,214,797...198,218,706
Ensembl chr 1:198,214,797...198,218,706
JBrowse link
G Tbxt T-box transcription factor T decreases expression ISO Butylated Hydroxyanisole results in decreased expression of T mRNA CTD PMID:28927898 NCBI chr 1:52,887,067...52,900,691
Ensembl chr 1:52,887,067...52,894,832
JBrowse link
G Tnf tumor necrosis factor multiple interactions
decreases response to substance
affects response to substance
ISO Butylated Hydroxyanisole inhibits the reaction [TNF protein results in decreased expression of ATP6V1A protein]; Butylated Hydroxyanisole inhibits the reaction [TNF protein results in decreased expression of COX2 protein]; Butylated Hydroxyanisole inhibits the reaction [TNF protein results in decreased expression of PSMC6 mRNA]; Butylated Hydroxyanisole inhibits the reaction [TNF protein results in increased abundance of Dinoprostone]; Butylated Hydroxyanisole inhibits the reaction [TNF protein results in increased secretion of Arachidonic Acid]
Butylated Hydroxyanisole results in decreased susceptibility to TNF protein
Butylated Hydroxyanisole affects the reaction [Dextran Sulfate affects the expression of TNF protein]; Butylated Hydroxyanisole inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; Butylated Hydroxyanisole inhibits the reaction [TNF protein results in increased abundance of Arachidonic Acid]; DUSP1 protein affects the reaction [Butylated Hydroxyanisole affects the reaction [Dextran Sulfate affects the expression of TNF protein]]; NFE2L2 protein affects the reaction [Butylated Hydroxyanisole affects the reaction [Dextran Sulfate affects the expression of TNF protein]]; TNFRSF1A protein affects the reaction [Butylated Hydroxyanisole inhibits the reaction [TNF protein results in increased abundance of Arachidonic Acid]]
Butylated Hydroxyanisole affects the susceptibility to TNF protein
CTD PMID:1515551, PMID:8186192, PMID:8740460, PMID:10588948, PMID:12470298, PMID:30844440 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfaip6 TNF alpha induced protein 6 multiple interactions ISO Butylated Hydroxyanisole inhibits the reaction [LHB protein results in increased abundance of TNFAIP6 mRNA] CTD PMID:21220312 NCBI chr 3:37,545,238...37,564,704
Ensembl chr 3:37,545,238...37,564,699
JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A multiple interactions ISO TNFRSF1A protein affects the reaction [Butylated Hydroxyanisole inhibits the reaction [TNF protein results in increased abundance of Arachidonic Acid]] CTD PMID:10588948 NCBI chr 4:157,864,905...157,877,634
Ensembl chr 4:157,864,969...157,877,633
JBrowse link
G Tp53 tumor protein p53 multiple interactions EXP
ISO
Butylated Hydroxyanisole inhibits the reaction [Methylnitrosourea results in increased phosphorylation of TP53 protein]
Butylated Hydroxyanisole inhibits the reaction [Methylnitrosourea results in increased phosphorylation of TRP53 protein]
CTD PMID:18593901 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases expression ISO Butylated Hydroxyanisole results in increased expression of UGT1A1 mRNA CTD PMID:18227147, PMID:19144771 NCBI chr 9:95,295,701...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 increases expression ISO Butylated Hydroxyanisole results in increased expression of UGT1A6 mRNA CTD PMID:19144771 NCBI chr 9:95,241,609...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt2b17 UDP glucuronosyltransferase family 2 member B17 decreases expression ISO Butylated Hydroxyanisole results in decreased expression of UGT2B1 mRNA CTD PMID:19144771 NCBI chr14:22,724,399...22,736,148
Ensembl chr14:22,724,070...22,825,444
JBrowse link
G Vegfa vascular endothelial growth factor A increases expression ISO Butylated Hydroxyanisole results in increased expression of VEGFA mRNA CTD PMID:19000923 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19816
    role 19764
      chemical role 19288
        antioxidant 14226
          3-tert-butyl-4-hydroxyanisole 118
            butylated hydroxyanisole 117
Path 2
Term Annotations click to browse term
  CHEBI ontology 19816
    subatomic particle 19814
      composite particle 19814
        hadron 19814
          baryon 19814
            nucleon 19814
              atomic nucleus 19814
                atom 19814
                  main group element atom 19702
                    p-block element atom 19702
                      carbon group element atom 19608
                        carbon atom 19597
                          organic molecular entity 19597
                            heteroorganic entity 19184
                              organochalcogen compound 18894
                                organooxygen compound 18816
                                  ether 16076
                                    aromatic ether 15562
                                      3-tert-butyl-4-hydroxyanisole 118
                                        butylated hydroxyanisole 117
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.