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Accession:CHEBI:77032 term browser browse the term
Definition:A substituted aniline that is 2,4-dibromoaniline which is substituted at position 6 by a [cyclohexyl(methyl)amino]methyl group. It is used (as the monohydrochloride salt) as a mucolytic for the treatment of respiratory disorders associated with productive cough (i.e. a cough characterised by the production of sputum).
Synonyms:exact_synonym: 2,4-dibromo-6-{[cyclohexyl(methyl)amino]methyl}aniline
 related_synonym: 3,5-dibromo-N(alpha)-cyclohexyl-N(alpha)-methyltoluene-alpha-2-diamine;   Fluibron;   Formula=C14H20Br2N2;   InChI=1S/C14H20Br2N2/c1-18(12-5-3-2-4-6-12)9-10-7-11(15)8-13(16)14(10)17/h7-8,12H,2-6,9,17H2,1H3;   InChIKey=OJGDCBLYJGHCIH-UHFFFAOYSA-N;   N-cyclohexyl-N-methyl-(2-amino-3,5-dibrombenzyl)amine;   SMILES=CN(Cc1cc(Br)cc(Br)c1N)C1CCCCC1;   bromhexina;   bromhexinum
 xref: Beilstein:2216008 "Beilstein";   CAS:3572-43-8 "ChemIDplus";   CAS:3572-43-8 "NIST Chemistry WebBook";   Drug_Central:402 "DrugCentral";   KEGG:D07542;   LINCS:LSM-3048
 xref_mesh: MESH:D001964
 xref: PMID:20031363 "Europe PMC";   PMID:22027391 "Europe PMC";   PMID:23781460 "Europe PMC";   PMID:4065592 "Europe PMC";   PMID:7027431 "Europe PMC";   PMID:7027873 "Europe PMC";   PMID:778563 "Europe PMC";   Patent:BE625022;   Wikipedia:Bromhexine
 cyclic_relationship: is_conjugate_base_of CHEBI:77040

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bromhexine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Kcnh2 potassium voltage-gated channel subfamily H member 2 JBrowse link 4 7,355,066 7,387,282 RGD:6480464
G Slc22a2 solute carrier family 22 member 2 JBrowse link 1 48,318,025 48,360,219 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19749
    role 19696
      application 19347
        pharmaceutical 19222
          drug 19222
            mucolytic 848
              bromhexine 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19749
    subatomic particle 19745
      composite particle 19745
        hadron 19745
          baryon 19745
            nucleon 19745
              atomic nucleus 19745
                atom 19745
                  main group element atom 19630
                    main group molecular entity 19630
                      s-block molecular entity 19390
                        hydrogen molecular entity 19379
                          hydrides 18296
                            inorganic hydride 17209
                              pnictogen hydride 17171
                                nitrogen hydride 17006
                                  azane 16699
                                    ammonia 16696
                                      organic amino compound 16695
                                        aromatic amine 13605
                                          anilines 12313
                                            substituted aniline 11809
                                              bromhexine 2
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