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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:expectorant
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Accession:CHEBI:77035 term browser browse the term
Definition:Compounds that are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing. Compare with mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration, and antitussives, which suppress the cough reflex.
Synonyms:related_synonym: expectorants
 xref: PMID:17594730


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(S)-naringenin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A increases expression ISO naringenin results in increased expression of ABCB1 mRNA CTD PMID:19148864 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 multiple interactions
increases activity
ISO [Glutathione co-treated with naringenin] inhibits the reaction [ABCC1 protein results in increased uptake of estradiol-17 beta-glucuronide]; Glutathione promotes the reaction [naringenin affects the reaction [ABCC1 protein results in increased uptake of Leukotriene C4]]; Glutathione promotes the reaction [naringenin results in increased activity of ABCC1 protein]; naringenin affects the reaction [ABCC1 protein results in increased uptake of Leukotriene C4]; naringenin inhibits the reaction [ABCC1 protein results in decreased susceptibility to Etoposide]; naringenin inhibits the reaction [ABCC1 protein results in increased export of S-(2,4-dinitrophenyl)glutathione]; naringenin promotes the reaction [ABCC1 protein results in increased hydrolysis of Adenosine Triphosphate]; naringenin promotes the reaction [ABCC1 protein results in increased uptake of Glutathione] CTD PMID:11306701, PMID:12485947, PMID:16156793 NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196
JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 multiple interactions ISO naringenin inhibits the reaction [ABCC4 protein results in increased export of Cyclic GMP]; naringenin promotes the reaction [ABCC4 protein results in increased hydrolysis of Adenosine Triphosphate] CTD PMID:16156793 NCBI chr15:103,695,415...103,927,980
Ensembl chr15:103,696,557...103,927,592
JBrowse link
G Abcc5 ATP binding cassette subfamily C member 5 multiple interactions ISO naringenin inhibits the reaction [ABCC5 protein results in decreased susceptibility to Thioguanine]; naringenin inhibits the reaction [ABCC5 protein results in increased export of 2',7'-bis(carboxyethyl)-5(6)-carboxyfluorescein] CTD PMID:16156793 NCBI chr11:84,395,982...84,490,215
Ensembl chr11:84,396,033...84,490,211
JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions EXP naringenin inhibits the reaction [Dimethylnitrosamine results in increased expression of ACTA2 protein] CTD PMID:14709902 NCBI chr 1:252,537,614...252,550,394
Ensembl chr 1:252,537,615...252,550,394
JBrowse link
G Afp alpha-fetoprotein affects binding EXP naringenin binds to AFP protein CTD PMID:23013281, PMID:25349334 NCBI chr14:19,141,755...19,159,919
Ensembl chr14:19,141,755...19,159,923
JBrowse link
G Ahr aryl hydrocarbon receptor increases activity
multiple interactions
ISO naringenin results in increased activity of AHR protein
naringenin inhibits the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of AHR protein]
naringenin inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to ARNT protein]]
CTD PMID:17869316, PMID:20450880 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 decreases activity ISO naringenin results in decreased activity of AKR1C3 protein CTD PMID:19007764 NCBI chr17:69,761,126...69,778,021
Ensembl chr17:69,761,118...69,778,021
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO
EXP
naringenin inhibits the reaction [bisphenol A results in increased activity of AKT1 protein]; naringenin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of AKT1 protein]
naringenin inhibits the reaction [TNF protein results in increased phosphorylation of AKT1 protein]
CTD PMID:22692793, PMID:22709785, PMID:25866363 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Alb albumin multiple interactions ISO naringenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Carboxymethylcellulose Sodium] results in increased expression of ALB protein] CTD PMID:31063766 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Alpl alkaline phosphatase, biomineralization associated multiple interactions ISO [naringenin binds to ESR1 protein] which results in increased activity of ALPL protein; fulvestrant inhibits the reaction [[naringenin binds to ESR1 protein] which results in increased activity of ALPL protein] CTD PMID:12650720 NCBI chr 5:156,086,496...156,141,513
Ensembl chr 5:156,086,497...156,141,537
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 increases expression ISO naringenin results in increased expression of APAF1 protein CTD PMID:27838343 NCBI chr 7:31,699,309...31,784,192
Ensembl chr 7:31,699,885...31,784,192
JBrowse link
G App amyloid beta precursor protein multiple interactions EXP naringenin inhibits the reaction [APP protein modified form results in increased abundance of Reactive Oxygen Species] CTD PMID:15030205 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858
JBrowse link
G Aqp1 aquaporin 1 multiple interactions ISO naringenin inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in decreased expression of AQP1 mRNA]; naringenin inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in decreased expression of AQP1 protein] CTD PMID:31301536 NCBI chr 4:85,551,503...85,563,683
Ensembl chr 4:85,551,502...85,569,360
JBrowse link
G Aqp5 aquaporin 5 multiple interactions ISO naringenin inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in decreased expression of AQP5 mRNA]; naringenin inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in decreased expression of AQP5 protein] CTD PMID:31301536 NCBI chr 7:141,249,044...141,252,576
Ensembl chr 7:141,249,044...141,252,578
JBrowse link
G Arhgdia Rho GDP dissociation inhibitor alpha increases expression ISO naringenin results in increased expression of ARHGDIA mRNA; naringenin results in increased expression of ARHGDIA protein CTD PMID:27838343 NCBI chr10:109,754,012...109,757,506
Ensembl chr10:109,754,004...109,757,550
JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator multiple interactions ISO naringenin inhibits the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of ARNT protein]
naringenin inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to ARNT protein]]
CTD PMID:20450880 NCBI chr 2:196,594,178...196,651,486
Ensembl chr 2:196,594,303...196,651,179
JBrowse link
G Bace1 beta-secretase 1 decreases activity ISO naringenin results in decreased activity of BACE1 protein CTD PMID:31194956 NCBI chr 8:50,140,092...50,162,388
Ensembl chr 8:50,139,997...50,162,361
JBrowse link
G Bak1 BCL2-antagonist/killer 1 increases expression ISO naringenin results in increased expression of BAK1 protein CTD PMID:27838343 NCBI chr20:5,609,620...5,618,899
Ensembl chr20:5,609,625...5,618,260
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
decreases expression
EXP
ISO
naringenin inhibits the reaction [Glucose results in increased expression of BAX mRNA]; naringenin inhibits the reaction [Glucose results in increased expression of BAX protein]
naringenin inhibits the reaction [Pyruvaldehyde results in increased expression of BAX protein]; naringenin inhibits the reaction [Tamoxifen results in decreased expression of BAX mRNA]; Tamoxifen promotes the reaction [naringenin results in decreased expression of BAX mRNA]
CTD PMID:23192364, PMID:30153467, PMID:31254498 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bche butyrylcholinesterase multiple interactions ISO naringenin inhibits the reaction [[Tritolyl Phosphates co-treated with NADP] results in decreased activity of BCHE protein] CTD PMID:23085349 NCBI chr 2:171,104,476...171,196,186
Ensembl chr 2:171,100,140...171,196,395
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
decreases expression
decreases response to substance
ISO
EXP
ethyl 2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate inhibits the reaction [BCL2 protein results in decreased susceptibility to naringenin]; naringenin inhibits the reaction [Pyruvaldehyde results in decreased expression of BCL2 protein]; naringenin promotes the reaction [Tamoxifen results in decreased expression of BCL2 mRNA]
naringenin results in decreased expression of BCL2 mRNA
naringenin inhibits the reaction [Glucose results in decreased expression of BCL2 mRNA]; naringenin inhibits the reaction [Glucose results in decreased expression of BCL2 protein]
CTD PMID:19124070, PMID:23192364, PMID:30153467, PMID:31254498 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression ISO naringenin results in decreased expression of BCL2L1 protein CTD PMID:27838343 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Casp3 caspase 3 increases activity
multiple interactions
increases expression
ISO
EXP
naringenin results in increased activity of CASP3 protein
naringenin inhibits the reaction [Pyruvaldehyde results in increased activity of CASP3 protein]
naringenin results in increased expression of CASP3 protein modified form
naringenin inhibits the reaction [Glucose results in increased activity of CASP3 protein]; naringenin inhibits the reaction [Glucose results in increased expression of and results in increased cleavage of CASP3 protein]; naringenin inhibits the reaction [Glucose results in increased expression of CASP3 mRNA]
CTD PMID:19124070, PMID:22692793, PMID:23192364, PMID:27838343, PMID:31254498 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp7 caspase 7 increases expression ISO naringenin results in increased expression of CASP7 protein modified form CTD PMID:27838343 NCBI chr 1:277,190,557...277,242,779
Ensembl chr 1:277,190,964...277,242,774
JBrowse link
G Casp9 caspase 9 increases activity
multiple interactions
increases expression
ISO
EXP
naringenin results in increased activity of CASP9 protein
naringenin inhibits the reaction [Pyruvaldehyde results in increased activity of CASP9 protein]
naringenin results in increased expression of CASP9 protein modified form
naringenin inhibits the reaction [Glucose results in increased expression of and results in increased cleavage of CASP9 protein]; naringenin inhibits the reaction [Glucose results in increased expression of CASP9 mRNA]
CTD PMID:19124070, PMID:23192364, PMID:27838343, PMID:31254498 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cat catalase multiple interactions
increases activity
EXP
ISO
naringenin inhibits the reaction [Arsenic Trioxide results in decreased activity of CAT protein]; naringenin inhibits the reaction [Cadmium Chloride results in decreased expression of CAT protein]; naringenin inhibits the reaction [Cadmium results in decreased activity of CAT protein]; naringenin inhibits the reaction [Dietary Fats results in decreased activity of CAT protein]; naringenin inhibits the reaction [Glucose results in decreased activity of CAT protein]; naringenin inhibits the reaction [Streptozocin results in decreased activity of CAT protein]
naringenin analog results in increased activity of CAT protein
naringenin inhibits the reaction [Carbon Tetrachloride results in decreased activity of CAT protein]
CTD PMID:19063931, PMID:19409769, PMID:23192364, PMID:23283742, PMID:23845967, PMID:27417253, PMID:29223569, PMID:30372826 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Ccnd1 cyclin D1 multiple interactions
decreases expression
ISO [Tamoxifen co-treated with naringenin] results in decreased expression of CCND1 mRNA
naringenin results in decreased expression of CCND1 mRNA
CTD PMID:30153467 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Ccne1 cyclin E1 decreases expression
multiple interactions
ISO naringenin results in decreased expression of CCNE1 mRNA
[Tamoxifen co-treated with naringenin] results in decreased expression of CCNE1 mRNA
CTD PMID:30153467 NCBI chr 1:94,485,830...94,495,112
Ensembl chr 1:94,485,832...94,494,980
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
increases expression
ISO [Tamoxifen co-treated with naringenin] results in increased expression of CDKN1A mRNA
naringenin results in increased expression of CDKN1A mRNA
CTD PMID:30153467 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cftr CF transmembrane conductance regulator multiple interactions ISO naringenin inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in decreased expression of CFTR mRNA]; naringenin inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in decreased expression of CFTR protein] CTD PMID:31301536 NCBI chr 4:42,693,263...42,860,679
Ensembl chr 4:42,692,836...42,860,676
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A multiple interactions EXP naringenin inhibits the reaction [Dietary Fats results in decreased expression of CPT1A mRNA] CTD PMID:30372826 NCBI chr 1:218,568,157...218,629,679
Ensembl chr 1:218,569,510...218,629,678
JBrowse link
G Ctsd cathepsin D multiple interactions ISO [naringenin results in increased phosphorylation of and results in increased activity of ESR1 protein] which results in increased expression of CTSD mRNA CTD PMID:24586459 NCBI chr 1:215,541,570...215,553,446
Ensembl chr 1:215,541,542...215,553,451
JBrowse link
G Cycs cytochrome c, somatic multiple interactions
increases expression
EXP
ISO
naringenin inhibits the reaction [Glucose affects the localization of CYCS protein]
naringenin results in increased expression of CYCS protein
CTD PMID:23192364, PMID:27838343 NCBI chr 4:80,331,226...80,333,326
Ensembl chr 4:80,331,227...80,333,326
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 multiple interactions
decreases activity
ISO
EXP
naringenin binds to and results in decreased activity of CYP19A1 protein
naringenin results in decreased activity of CYP19A1 protein
CTD PMID:9435150, PMID:15319488, PMID:17895526 NCBI chr 8:58,744,849...58,772,408
Ensembl chr 8:58,744,849...58,772,408
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
decreases activity
increases expression
ISO
EXP
naringenin binds to and results in decreased activity of CYP1A1 protein; naringenin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]
naringenin results in decreased activity of CYP1A1 protein
naringenin results in increased expression of CYP1A1 mRNA
naringenin promotes the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]
CTD PMID:11454723, PMID:20930378, PMID:21053930, PMID:27444380 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases activity ISO naringenin results in decreased activity of CYP1A2 protein CTD PMID:21053930, PMID:29753067 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions
increases expression
ISO naringenin binds to and results in decreased activity of CYP1B1 protein
naringenin results in increased expression of CYP1B1 mRNA
CTD PMID:21053930, PMID:31621310 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 decreases activity ISO naringenin results in decreased activity of CYP2C19 protein CTD PMID:29753067 NCBI chr 1:147,713,879...147,814,410
Ensembl chr 1:147,713,892...147,888,007
JBrowse link
G Egfr epidermal growth factor receptor multiple interactions ISO naringenin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of EGFR protein] CTD PMID:25866363 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
JBrowse link
G Esr1 estrogen receptor 1 affects activity
increases expression
decreases expression
affects binding
increases activity
multiple interactions
ISO
EXP
naringenin affects the activity of ESR1 protein
naringenin results in increased expression of ESR1 mRNA
naringenin results in decreased expression of ESR1 mRNA; naringenin results in decreased expression of ESR1 mRNA alternative form; naringenin results in decreased expression of ESR1 protein alternative form
naringenin binds to ESR1 protein
naringenin results in increased activity of ESR1 protein
[naringenin binds to ESR1 protein] which results in increased activity of ALPL protein; [naringenin results in increased phosphorylation of and results in increased activity of ESR1 protein] which results in increased expression of CTSD mRNA; [naringenin results in increased phosphorylation of and results in increased activity of ESR1 protein] which results in increased expression of PGR mRNA; [naringenin results in increased phosphorylation of and results in increased activity of ESR1 protein] which results in increased expression of PSEN2 mRNA; [SB 203580 co-treated with naringenin] results in increased degradation of ESR1 protein; [Tamoxifen co-treated with naringenin] results in decreased expression of ESR1 mRNA; [Tamoxifen co-treated with naringenin] results in decreased expression of ESR1 mRNA alternative form; [Tamoxifen co-treated with naringenin] results in decreased expression of ESR1 protein; [Tamoxifen co-treated with naringenin] results in decreased expression of ESR1 protein alternative form; Fulvestrant inhibits the reaction [[naringenin binds to ESR1 protein] which results in increased activity of ALPL protein]; naringenin binds to and results in increased activity of ESR1 protein; naringenin inhibits the reaction [Cycloheximide results in decreased expression of ESR1 protein]; naringenin inhibits the reaction [Estradiol results in decreased expression of ESR1 protein]; naringenin promotes the reaction [ESR1 protein binds to ESR1 protein]; naringenin results in increased phosphorylation of and results in increased activity of ESR1 protein
CTD PMID:9751507, PMID:10397250, PMID:10854714, PMID:12650720, PMID:15185748, PMID:15713566, PMID:16118406, PMID:19913605, PMID:22692793, PMID:24586459, PMID:30153467 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Esr2 estrogen receptor 2 multiple interactions
increases expression
increases activity
affects binding
ISO
EXP
[Tamoxifen co-treated with naringenin] results in increased expression of ESR2 mRNA; [Tamoxifen co-treated with naringenin] results in increased expression of ESR2 protein; naringenin binds to and results in increased activity of ESR2 protein; naringenin inhibits the reaction [Estradiol binds to ESR2 protein]
naringenin results in increased expression of ESR2 mRNA; naringenin results in increased expression of ESR2 protein
naringenin results in increased activity of ESR2 protein
naringenin binds to ESR2 protein
CTD PMID:9751507, PMID:12224631, PMID:16118406, PMID:16566672, PMID:17716812, PMID:19913605, PMID:30153467 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase multiple interactions
decreases activity
EXP
ISO
[naringenin co-treated with lead acetate] results in decreased activity of G6PD protein; naringenin inhibits the reaction [Cadmium Chloride results in decreased expression of G6PD protein]
naringenin results in decreased activity of G6PD protein
CTD PMID:19063931, PMID:25130191, PMID:25228019 NCBI chr  X:156,274,800...156,293,935
Ensembl chr  X:156,274,800...156,293,926
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions
increases expression
ISO NFE2L2 protein affects the reaction [naringenin results in increased expression of GCLC protein] CTD PMID:31254498 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression
multiple interactions
ISO naringenin results in increased expression of GCLM protein
NFE2L2 protein affects the reaction [naringenin results in increased expression of GCLM protein]
CTD PMID:31254498 NCBI chr 2:225,827,504...225,847,876
Ensembl chr 2:225,827,504...225,847,874
JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 multiple interactions
decreases expression
ISO [Tamoxifen co-treated with naringenin] results in decreased expression of GPER1 mRNA; [Tamoxifen co-treated with naringenin] results in decreased expression of GPER1 protein
naringenin results in decreased expression of GPER1 mRNA; naringenin results in decreased expression of GPER1 protein
CTD PMID:30153467 NCBI chr12:17,309,122...17,315,267
Ensembl chr12:17,309,834...17,311,112
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions EXP naringenin inhibits the reaction [arsenic trioxide results in increased activity of GPT protein]; naringenin inhibits the reaction [Streptozocin results in increased activity of GPT protein] CTD PMID:23283742, PMID:29223569 NCBI chr 7:117,759,083...117,761,932
Ensembl chr 7:117,759,083...117,761,931
JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions EXP naringenin inhibits the reaction [Glucose results in decreased expression of GPX1 mRNA] CTD PMID:23192364 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
JBrowse link
G Gpx2 glutathione peroxidase 2 multiple interactions
increases expression
ISO [Paraquat co-treated with naringenin] results in increased expression of GPX2 mRNA
naringenin results in increased expression of GPX2 mRNA
CTD PMID:24561720 NCBI chr 6:99,839,960...99,843,245
Ensembl chr 6:99,839,960...99,843,245
JBrowse link
G Gpx3 glutathione peroxidase 3 multiple interactions ISO [Paraquat co-treated with naringenin] results in increased expression of GPX3 mRNA CTD PMID:24561720 NCBI chr10:40,247,436...40,255,423
Ensembl chr10:40,247,436...40,255,422
JBrowse link
G Gpx5 glutathione peroxidase 5 increases expression
multiple interactions
ISO naringenin results in increased expression of GPX5 mRNA
[Paraquat co-treated with naringenin] results in increased expression of GPX5 mRNA
CTD PMID:24561720 NCBI chr17:45,508,657...45,518,686
Ensembl chr17:45,467,015...45,518,686
JBrowse link
G Gpx7 glutathione peroxidase 7 multiple interactions
increases expression
ISO [Paraquat co-treated with naringenin] results in increased expression of GPX7 mRNA
naringenin results in increased expression of GPX7 mRNA
CTD PMID:24561720 NCBI chr 5:128,001,766...128,009,610
Ensembl chr 5:128,001,761...128,009,735
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions
increases expression
EXP
ISO
naringenin inhibits the reaction [Cadmium Chloride results in decreased expression of GSR protein]; naringenin inhibits the reaction [Glucose results in decreased expression of GSR mRNA]
Paraquat inhibits the reaction [naringenin results in increased expression of GSR mRNA]
CTD PMID:19063931, PMID:23192364, PMID:24561720 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Gstz1 glutathione S-transferase zeta 1 multiple interactions
increases expression
ISO Paraquat inhibits the reaction [naringenin results in increased expression of GSTZ1 mRNA] CTD PMID:24561720 NCBI chr 6:111,176,798...111,187,246
Ensembl chr 6:111,176,798...111,187,244
JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 multiple interactions ISO naringenin inhibits the reaction [Carbon Tetrachloride results in increased expression of HAVCR1 protein] CTD PMID:23845967 NCBI chr10:31,813,819...31,860,934
Ensembl chr10:31,813,814...31,848,379
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression
EXP
ISO
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [naringenin results in increased expression of HMOX1 protein]; naringenin inhibits the reaction [TNF protein results in decreased expression of and results in decreased activity of HMOX1 protein]; naringenin inhibits the reaction [TNF protein results in decreased expression of HMOX1 mRNA]; naringenin results in increased expression of and results in increased activity of HMOX1 protein; wortmannin inhibits the reaction [naringenin results in increased expression of HMOX1 protein]
naringenin results in increased expression of HMOX1 mRNA; naringenin results in increased expression of HMOX1 protein
[Paraquat co-treated with naringenin] results in increased expression of HMOX1 mRNA
naringenin promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of HMOX1 protein]
CTD PMID:15316927, PMID:22709785, PMID:24561720 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 multiple interactions
decreases activity
ISO Amiodarone promotes the reaction [naringenin results in decreased activity of KCNH2 protein]; azimilide promotes the reaction [naringenin results in decreased activity of KCNH2 protein]; dofetilide promotes the reaction [naringenin results in decreased activity of KCNH2 protein]; naringenin promotes the reaction [Amiodarone results in decreased activity of KCNH2 protein]; naringenin promotes the reaction [azimilide results in decreased activity of KCNH2 protein]; naringenin promotes the reaction [dofetilide results in decreased activity of KCNH2 protein]; naringenin promotes the reaction [Quinidine results in decreased activity of KCNH2 protein]; Quinidine promotes the reaction [naringenin results in decreased activity of KCNH2 protein] CTD PMID:18057881 NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253
JBrowse link
G Lpo lactoperoxidase increases expression
multiple interactions
ISO naringenin results in increased expression of LPO mRNA
Paraquat inhibits the reaction [naringenin results in increased expression of LPO mRNA]
CTD PMID:24561720 NCBI chr10:75,100,385...75,120,247
Ensembl chr10:75,100,385...75,120,247
JBrowse link
G Lrrc27 leucine rich repeat containing 27 increases expression ISO naringenin results in increased expression of LRRC27 mRNA; naringenin results in increased expression of LRRC27 protein CTD PMID:27838343 NCBI chr 1:211,543,751...211,575,823
Ensembl chr 1:211,543,751...211,575,820
JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 increases expression ISO naringenin results in increased expression of MAP3K5 protein CTD PMID:27838343 NCBI chr 1:15,412,603...15,613,752
Ensembl chr 1:15,412,603...15,613,746
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
decreases activity
decreases phosphorylation
EXP
ISO
naringenin inhibits the reaction [TNF protein results in increased phosphorylation of MAPK1 protein]
naringenin results in decreased activity of MAPK1 protein
naringenin results in decreased phosphorylation of MAPK1 protein
naringenin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]
naringenin inhibits the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of MAPK1 protein]
CTD PMID:20450880, PMID:22709785, PMID:25866363, PMID:27468969, PMID:30431227 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
decreases activity
decreases phosphorylation
EXP
ISO
naringenin inhibits the reaction [TNF protein results in increased phosphorylation of MAPK3 protein]
naringenin results in decreased activity of MAPK3 protein
naringenin results in decreased phosphorylation of MAPK3 protein
naringenin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]
naringenin inhibits the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of MAPK3 protein]
CTD PMID:20450880, PMID:22709785, PMID:25866363, PMID:27468969, PMID:30431227 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases phosphorylation ISO naringenin results in increased phosphorylation of MAPK8 protein CTD PMID:27838343 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 increases phosphorylation ISO naringenin results in increased phosphorylation of MAPK9 protein CTD PMID:27838343 NCBI chr10:35,333,859...35,374,364
Ensembl chr10:35,333,859...35,374,355
JBrowse link
G Mmp2 matrix metallopeptidase 2 decreases expression
multiple interactions
ISO naringenin results in decreased expression of MMP2 mRNA
naringenin results in decreased expression of and results in decreased activity of MMP2 protein
CTD PMID:30153467, PMID:30431227 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
decreases expression
ISO naringenin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; naringenin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased secretion of MMP9 protein]; naringenin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; naringenin results in decreased expression of and results in decreased activity of MMP9 protein
naringenin results in decreased expression of MMP9 mRNA
CTD PMID:25866363, PMID:30153467, PMID:30431227 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Nanog Nanog homeobox decreases expression ISO naringenin results in decreased expression of NANOG protein CTD PMID:27468969 NCBI chr 4:155,531,906...155,539,268
Ensembl chr 4:155,531,906...155,539,268
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 multiple interactions
increases activity
increases expression
ISO [naringenin co-treated with Paraquat] results in increased expression of NFE2L2 protein; naringenin results in increased expression of and affects the localization of NFE2L2 protein; NFE2L2 protein affects the reaction [naringenin results in increased expression of GCLC protein]; NFE2L2 protein affects the reaction [naringenin results in increased expression of GCLM protein]
naringenin results in increased activity of NFE2L2 protein
naringenin results in increased expression of NFE2L2 mRNA
CTD PMID:24561720, PMID:31254498 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO naringenin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased degradation of NFKBIA protein] CTD PMID:10188978 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Nfkbil1 NFKB inhibitor like 1 increases expression ISO naringenin results in increased expression of NFKBIL1 mRNA; naringenin results in increased expression of NFKBIL1 protein CTD PMID:27838343 NCBI chr20:4,823,590...4,839,202
Ensembl chr20:4,822,935...4,839,202
JBrowse link
G Nme1 NME/NM23 nucleoside diphosphate kinase 1 increases expression ISO naringenin results in increased expression of NME1 mRNA; naringenin results in increased expression of NME1 protein CTD PMID:27838343 NCBI chr10:81,657,152...81,666,542
Ensembl chr10:81,657,153...81,666,523
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO Hemin promotes the reaction [naringenin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of NOS2 protein]]; naringenin inhibits the reaction [[Lipopolysaccharides results in increased expression of NOS2 protein] which results in increased chemical synthesis of Nitric Oxide]; naringenin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of NOS2 mRNA]; naringenin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of NOS2 protein]; naringenin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; naringenin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] CTD PMID:10188978, PMID:12512693, PMID:15316927, PMID:18274639 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions
increases expression
ISO [Paraquat co-treated with naringenin] results in increased expression of NQO1 mRNA
naringenin results in increased expression of NQO1 mRNA; naringenin results in increased expression of NQO1 protein
CTD PMID:24561720 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity ISO naringenin results in increased activity of NR1I2 protein CTD PMID:25455453 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage
multiple interactions
ISO naringenin results in increased cleavage of PARP1 protein
naringenin inhibits the reaction [Pyruvaldehyde results in increased cleavage of PARP1 protein]
CTD PMID:27838343, PMID:31254498 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Pgd phosphogluconate dehydrogenase decreases activity ISO naringenin results in decreased activity of PGD protein CTD PMID:25130191 NCBI chr 5:165,966,128...165,982,327 JBrowse link
G Pgr progesterone receptor increases expression
multiple interactions
EXP
ISO
naringenin results in increased expression of PGR mRNA
[naringenin results in increased phosphorylation of and results in increased activity of ESR1 protein] which results in increased expression of PGR mRNA
CTD PMID:10397250, PMID:24586459 NCBI chr 8:7,128,656...7,187,796
Ensembl chr 8:7,128,656...7,187,796
JBrowse link
G Pon1 paraoxonase 1 increases expression ISO naringenin results in increased expression of PON1 mRNA CTD PMID:15169886 NCBI chr 4:30,249,749...30,276,297
Ensembl chr 4:30,249,742...30,276,372
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions EXP
ISO
N-hydroxy-N'-(4-butyl-2-methylphenyl)formamidine inhibits the reaction [naringenin inhibits the reaction [Glucose results in decreased expression of PPARA protein]]; naringenin inhibits the reaction [Glucose results in decreased expression of PPARA protein]
naringenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Carboxymethylcellulose Sodium] results in decreased expression of PPARA protein]
CTD PMID:31063766 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
JBrowse link
G Ppard peroxisome proliferator-activated receptor delta multiple interactions ISO
EXP
naringenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Carboxymethylcellulose Sodium] results in decreased expression of PPARB protein]
N-hydroxy-N'-(4-butyl-2-methylphenyl)formamidine inhibits the reaction [naringenin inhibits the reaction [Glucose results in decreased expression of PPARB protein]]; naringenin inhibits the reaction [Glucose results in decreased expression of PPARB protein]
CTD PMID:31063766 NCBI chr20:7,818,289...7,883,482
Ensembl chr20:7,818,289...7,885,333
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions EXP
ISO
N-hydroxy-N'-(4-butyl-2-methylphenyl)formamidine inhibits the reaction [naringenin inhibits the reaction [Glucose results in decreased expression of PPARG protein]]; naringenin inhibits the reaction [Glucose results in decreased expression of PPARG protein]; naringenin inhibits the reaction [Streptozocin results in decreased expression of PPARG mRNA]; naringenin inhibits the reaction [Streptozocin results in decreased expression of PPARG protein]
naringenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Carboxymethylcellulose Sodium] results in decreased expression of PPARG protein]
CTD PMID:29223569, PMID:31063766 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Prdx1 peroxiredoxin 1 decreases expression ISO naringenin results in decreased expression of PRDX1 mRNA; naringenin results in decreased expression of PRDX1 protein CTD PMID:27838343 NCBI chr 5:135,536,413...135,551,986
Ensembl chr 5:135,536,413...135,551,990
JBrowse link
G Prkca protein kinase C, alpha multiple interactions ISO naringenin inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of PRKCA protein] CTD PMID:25866363 NCBI chr10:96,186,509...96,585,168
Ensembl chr10:96,191,133...96,584,947
JBrowse link
G Prkcb protein kinase C, beta multiple interactions ISO naringenin inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of PRKCB protein] CTD PMID:25866363 NCBI chr 1:192,233,569...192,575,339
Ensembl chr 1:192,233,910...192,574,831
JBrowse link
G Prkcg protein kinase C, gamma multiple interactions ISO naringenin inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of PRKCG protein] CTD PMID:25866363 NCBI chr 1:64,407,098...64,433,698
Ensembl chr 1:64,407,114...64,433,636
JBrowse link
G Prom1 prominin 1 decreases expression ISO naringenin results in decreased expression of PROM1 protein CTD PMID:27468969 NCBI chr14:71,532,321...71,637,400
Ensembl chr14:71,533,063...71,637,417
JBrowse link
G Psen2 presenilin 2 multiple interactions ISO [naringenin results in increased phosphorylation of and results in increased activity of ESR1 protein] which results in increased expression of PSEN2 mRNA CTD PMID:24586459 NCBI chr13:98,513,600...98,539,347
Ensembl chr13:98,513,570...98,530,724
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 increases expression ISO naringenin results in increased expression of PTGS1 mRNA CTD PMID:24561720 NCBI chr 3:15,560,685...15,582,339
Ensembl chr 3:15,560,712...15,582,344
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO naringenin inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA] CTD PMID:21341175 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO naringenin inhibits the reaction [Lipopolysaccharides affects the localization of and results in increased activity of RELA protein] CTD PMID:18274639 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Rptor regulatory associated protein of MTOR, complex 1 increases expression ISO naringenin results in increased expression of RPTOR mRNA; naringenin results in increased expression of RPTOR protein CTD PMID:27838343 NCBI chr10:108,750,620...109,058,691
Ensembl chr10:108,750,620...109,058,691
JBrowse link
G Serpine1 serpin family E member 1 multiple interactions EXP naringenin inhibits the reaction [TNF protein results in increased expression of SERPINE1 mRNA] CTD PMID:22709785 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482
JBrowse link
G Shbg sex hormone binding globulin affects binding ISO naringenin binds to SHBG protein CTD PMID:25349334 NCBI chr10:56,219,861...56,237,354
Ensembl chr10:56,219,858...56,223,245
JBrowse link
G Si sucrase-isomaltase decreases activity
multiple interactions
EXP
ISO
naringenin results in decreased activity of SI protein
naringenin binds to and results in decreased activity of SI protein
CTD PMID:24412302 NCBI chr 2:170,220,794...170,301,348
Ensembl chr 2:170,221,245...170,301,348
JBrowse link
G Slc16a1 solute carrier family 16 member 1 multiple interactions ISO
EXP
naringenin inhibits the reaction [SLC16A1 protein results in increased uptake of Benzoic Acid]
[naringenin results in decreased activity of SLC16A1 protein] which results in decreased uptake of Sodium Oxybate
CTD PMID:17108059, PMID:17976262 NCBI chr 2:207,108,552...207,129,352
Ensembl chr 2:207,108,552...207,128,554
JBrowse link
G Slc2a1 solute carrier family 2 member 1 multiple interactions
decreases activity
ISO naringenin inhibits the reaction [SLC2A1 protein affects the transport of Glucose]
naringenin results in decreased activity of SLC2A1 protein
CTD PMID:14642735 NCBI chr 5:138,154,677...138,182,897
Ensembl chr 5:138,154,673...138,182,897
JBrowse link
G Slc2a4 solute carrier family 2 member 4 multiple interactions EXP naringenin inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 mRNA]; naringenin inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 protein] CTD PMID:29223569 NCBI chr10:56,552,921...56,558,562
Ensembl chr10:56,552,983...56,558,487
JBrowse link
G Slc5a1 solute carrier family 5 member 1 multiple interactions ISO naringenin inhibits the reaction [SLC5A1 protein results in increased uptake of methylglucoside] CTD PMID:17495124 NCBI chr14:82,910,448...82,975,303
Ensembl chr14:82,909,981...82,975,263
JBrowse link
G Slco1b2 solute carrier organic anion transporter family member 1B2 multiple interactions ISO naringenin inhibits the reaction [SLCO1B3 protein results in increased import of Sulfobromophthalein] CTD PMID:22394605 NCBI chr 4:175,814,118...175,881,775
Ensembl chr 4:175,814,118...175,881,768
JBrowse link
G Snai1 snail family transcriptional repressor 1 decreases expression ISO naringenin results in decreased expression of SNAI1 protein CTD PMID:30431227 NCBI chr 3:164,274,710...164,279,199
Ensembl chr 3:164,274,710...164,279,378
JBrowse link
G Snai2 snail family transcriptional repressor 2 decreases expression ISO naringenin results in decreased expression of SNAI2 protein CTD PMID:30431227 NCBI chr11:90,404,421...90,406,730
Ensembl chr11:90,403,333...90,406,797
JBrowse link
G Socs3 suppressor of cytokine signaling 3 increases expression ISO naringenin results in increased expression of SOCS3 mRNA CTD PMID:23782265 NCBI chr10:106,973,863...106,976,969
Ensembl chr10:106,975,178...106,976,040
JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions EXP naringenin inhibits the reaction [Glucose results in increased expression of SOD1 mRNA] CTD PMID:23192364 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions EXP naringenin inhibits the reaction [Glucose results in decreased expression of SOD2 mRNA] CTD PMID:23192364 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Sox2 SRY-box transcription factor 2 decreases expression ISO naringenin results in decreased expression of SOX2 protein CTD PMID:27468969 NCBI chr 2:121,165,137...121,167,545
Ensembl chr 2:121,165,137...121,167,545
JBrowse link
G Spp1 secreted phosphoprotein 1 multiple interactions EXP naringenin inhibits the reaction [TNF protein results in increased expression of SPP1 mRNA] CTD PMID:22709785 NCBI chr14:6,673,686...6,679,965
Ensembl chr14:6,673,686...6,679,901
JBrowse link
G Stat3 signal transducer and activator of transcription 3 decreases phosphorylation ISO naringenin results in decreased phosphorylation of STAT3 protein CTD PMID:27468969 NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233
JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 multiple interactions ISO
EXP
Mefenamic Acid inhibits the reaction [SULT1A1 protein results in increased sulfation of naringenin] CTD PMID:11181495 NCBI chr 1:198,100,586...198,104,106
Ensembl chr 1:198,100,586...198,104,109
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO naringenin inhibits the reaction [Carbon Tetrachloride results in increased expression of TGFB1 protein] CTD PMID:23845967 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tnf tumor necrosis factor multiple interactions
decreases activity
ISO
EXP
naringenin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of TNF protein]
naringenin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF]
naringenin results in decreased activity of TNF protein
naringenin inhibits the reaction [TNF protein results in decreased expression of and results in decreased activity of HMOX1 protein]; naringenin inhibits the reaction [TNF protein results in decreased expression of HMOX1 mRNA]; naringenin inhibits the reaction [TNF protein results in increased expression of SERPINE1 mRNA]; naringenin inhibits the reaction [TNF protein results in increased expression of SPP1 mRNA]; naringenin inhibits the reaction [TNF protein results in increased phosphorylation of AKT1 protein]; naringenin inhibits the reaction [TNF protein results in increased phosphorylation of MAPK1 protein]; naringenin inhibits the reaction [TNF protein results in increased phosphorylation of MAPK3 protein]; zinc protoporphyrin inhibits the reaction [naringenin results in decreased activity of TNF protein]
CTD PMID:18720166, PMID:19135038, PMID:22709785 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tp53 tumor protein p53 multiple interactions
increases expression
ISO [Tamoxifen co-treated with naringenin] results in increased expression of TP53 mRNA; naringenin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of and results in increased activity of TP53 protein]; naringenin results in increased expression of and results in increased phosphorylation of TP53 protein
naringenin results in increased expression of TP53 mRNA
CTD PMID:15795422, PMID:27838343, PMID:30153467 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Tpo thyroid peroxidase decreases activity EXP naringenin results in decreased activity of TPO protein CTD PMID:26884060 NCBI chr 6:49,020,918...49,089,855
Ensembl chr 6:49,021,044...49,089,855
JBrowse link
G Ucp1 uncoupling protein 1 multiple interactions EXP naringenin inhibits the reaction [Dietary Fats results in decreased expression of UCP1 mRNA] CTD PMID:30372826 NCBI chr19:24,456,976...24,464,808
Ensembl chr19:24,456,976...24,464,807
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases glucuronidation
increases expression
ISO UGT1A1 protein results in increased glucuronidation of naringenin
naringenin results in increased expression of UGT1A1 mRNA
CTD PMID:14557274, PMID:31621310 NCBI chr 9:95,295,701...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt1a8 UDP glucuronosyltransferase family 1 member A8 increases glucuronidation ISO UGT1A8 protein results in increased glucuronidation of naringenin CTD PMID:14557274 NCBI chr 9:95,221,474...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 increases glucuronidation ISO UGT1A9 protein results in increased glucuronidation of naringenin CTD PMID:14557274, PMID:18816295 NCBI chr 9:95,161,157...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt2b15 UDP glucuronosyltransferase family 2 member B15 increases metabolic processing EXP UGT2B15 protein results in increased metabolism of naringenin CTD PMID:7574722 NCBI chr14:22,375,428...22,486,291
Ensembl chr14:22,375,955...22,534,720
JBrowse link
6-prenylnaringenin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression ISO 6-prenylnaringenin results in increased expression of CYP1A1 mRNA CTD PMID:27269377 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases expression ISO 6-prenylnaringenin results in increased expression of CYP1B1 mRNA CTD PMID:27269377 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
emetine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ago3 argonaute RISC catalytic component 3 multiple interactions ISO Emetine inhibits the reaction [Thapsigargin affects the localization of AGO3 mRNA] CTD PMID:29576526 NCBI chr 5:144,355,792...144,436,509
Ensembl chr 5:144,364,269...144,436,509
JBrowse link
G Akap9 A-kinase anchoring protein 9 multiple interactions ISO Emetine inhibits the reaction [sodium arsenite affects the localization of AKAP9 protein] CTD PMID:19073175 NCBI chr 4:27,195,346...27,331,582
Ensembl chr 4:27,195,346...27,331,582
JBrowse link
G Ar androgen receptor multiple interactions ISO Emetine binds to and results in decreased activity of AR protein CTD PMID:25752796 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Brca1 BRCA1, DNA repair associated multiple interactions ISO Emetine inhibits the reaction [Thapsigargin affects the localization of BRCA1 mRNA] CTD PMID:29576526 NCBI chr10:89,394,821...89,455,093
Ensembl chr10:89,394,803...89,454,681
JBrowse link
G Caprin1 cell cycle associated protein 1 multiple interactions ISO Emetine inhibits the reaction [sodium arsenite affects the localization of CAPRIN1 protein] CTD PMID:19073175 NCBI chr 3:93,701,830...93,789,580
Ensembl chr 3:93,702,487...93,789,617
JBrowse link
G Casp3 caspase 3 increases activity ISO Emetine results in increased activity of CASP3 protein CTD PMID:14502240 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp9 caspase 9 increases activity ISO Emetine results in increased activity of CASP9 protein CTD PMID:14502240 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Ccar1 cell division cycle and apoptosis regulator 1 multiple interactions ISO Emetine inhibits the reaction [sodium arsenite affects the localization of CCAR1 protein] CTD PMID:19073175 NCBI chr20:32,373,443...32,416,044
Ensembl chr20:32,373,443...32,416,044
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases expression ISO Emetine results in decreased expression of CCL2 protein CTD PMID:20116850 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 decreases expression ISO Emetine results in decreased expression of CCL3 protein CTD PMID:20116850 NCBI chr10:70,869,516...70,871,066
Ensembl chr10:70,869,513...70,871,066
JBrowse link
G Ccl4 C-C motif chemokine ligand 4 decreases expression ISO Emetine results in decreased expression of CCL4 protein CTD PMID:20116850 NCBI chr10:70,870,926...70,886,357
Ensembl chr10:70,884,531...70,886,355
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 decreases expression ISO Emetine results in decreased expression of CCL5 protein CTD PMID:20116850 NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions ISO Emetine inhibits the reaction [Thapsigargin affects the localization of CREB1 mRNA] CTD PMID:29576526 NCBI chr 9:71,229,753...71,298,994
Ensembl chr 9:71,230,108...71,293,435
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO Emetine binds to and results in decreased activity of ESR1 protein CTD PMID:25752796 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Esr2 estrogen receptor 2 multiple interactions ISO Emetine binds to and results in decreased activity of ESR2 protein CTD PMID:25752796 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
JBrowse link
G Il6r interleukin 6 receptor decreases expression ISO Emetine results in decreased expression of IL6R protein modified form CTD PMID:20116850 NCBI chr 2:189,196,180...189,255,987
Ensembl chr 2:189,205,701...189,254,628
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
decreases phosphorylation
increases phosphorylation
ISO 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [Emetine results in increased phosphorylation of MAPK1 protein]
MAPK14 mutant form inhibits the reaction [Emetine results in decreased phosphorylation of MAPK1 protein]
CTD PMID:15772366, PMID:26332055 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk14 mitogen activated protein kinase 14 multiple interactions ISO Emetine results in increased phosphorylation of and results in increased activity of MAPK14 protein; MAPK14 mutant form inhibits the reaction [Emetine results in decreased activity of MMP2 protein]; MAPK14 mutant form inhibits the reaction [Emetine results in decreased activity of MMP9 protein]; MAPK14 mutant form inhibits the reaction [Emetine results in decreased phosphorylation of MAPK1 protein]; MAPK14 mutant form inhibits the reaction [Emetine results in decreased phosphorylation of MAPK3 protein] CTD PMID:16364386, PMID:26332055 NCBI chr20:5,933,290...5,995,137
Ensembl chr20:5,933,303...5,995,137
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation
decreases phosphorylation
multiple interactions
ISO Emetine results in increased phosphorylation of MAPK3 protein
Emetine results in decreased phosphorylation of MAPK3 protein
MAPK14 mutant form inhibits the reaction [Emetine results in decreased phosphorylation of MAPK3 protein]
4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [Emetine results in increased phosphorylation of MAPK3 protein]
CTD PMID:15772366, PMID:26332055 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions
increases phosphorylation
ISO 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [Emetine results in increased phosphorylation of MAPK8 protein] CTD PMID:15772366 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions
increases phosphorylation
ISO 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [Emetine results in increased phosphorylation of MAPK9 protein] CTD PMID:15772366 NCBI chr10:35,333,859...35,374,364
Ensembl chr10:35,333,859...35,374,355
JBrowse link
G Mapt microtubule-associated protein tau decreases expression ISO Emetine results in decreased expression of MAPT protein CTD PMID:16930453 NCBI chr10:92,289,002...92,386,517
Ensembl chr10:92,288,910...92,386,517
JBrowse link
G Mmp2 matrix metallopeptidase 2 decreases activity
multiple interactions
decreases expression
ISO Emetine results in decreased activity of MMP2 protein
MAPK14 mutant form inhibits the reaction [Emetine results in decreased activity of MMP2 protein]
Emetine results in decreased expression of MMP2 mRNA
CTD PMID:26332055 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Mmp9 matrix metallopeptidase 9 decreases activity
multiple interactions
decreases expression
ISO Emetine results in decreased activity of MMP9 protein
MAPK14 mutant form inhibits the reaction [Emetine results in decreased activity of MMP9 protein]
Emetine results in decreased expression of MMP9 mRNA
CTD PMID:26332055 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions ISO Emetine inhibits the reaction [pregna-4,17-diene-3,16-dione results in decreased activity of NR1H4 protein] CTD PMID:25257666 NCBI chr 7:30,003,429...30,162,095
Ensembl chr 7:30,003,429...30,162,056
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage ISO Emetine results in increased cleavage of PARP1 protein CTD PMID:21256112 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Pgr progesterone receptor multiple interactions ISO Emetine binds to and results in decreased activity of PGR protein CTD PMID:25752796 NCBI chr 8:7,128,656...7,187,796
Ensembl chr 8:7,128,656...7,187,796
JBrowse link
G Reck reversion-inducing-cysteine-rich protein with kazal motifs decreases expression ISO Emetine results in decreased expression of RECK mRNA CTD PMID:26332055 NCBI chr 5:59,348,568...59,415,169
Ensembl chr 5:59,348,639...59,415,135
JBrowse link
G Rictor RPTOR independent companion of MTOR, complex 2 multiple interactions ISO Emetine inhibits the reaction [Thapsigargin affects the localization of RICTOR mRNA] CTD PMID:29576526 NCBI chr 2:56,013,898...56,105,818
Ensembl chr 2:56,052,643...56,101,803
JBrowse link
G Tardbp TAR DNA binding protein multiple interactions ISO Emetine affects the reaction [TARDBP protein binds to TIA1 protein]; Emetine affects the reaction [TARDBP protein binds to TIAR protein] CTD PMID:19765185 NCBI chr 5:165,432,089...165,442,232
Ensembl chr 5:165,432,095...165,442,048
JBrowse link
G Tgfb1 transforming growth factor, beta 1 decreases activity ISO Emetine results in decreased activity of TGFB1 protein CTD PMID:31652400 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Thra thyroid hormone receptor alpha multiple interactions ISO Emetine binds to and results in decreased activity of THRA protein CTD PMID:25752796 NCBI chr10:86,657,285...86,684,935
Ensembl chr10:86,657,285...86,684,933
JBrowse link
G Thrb thyroid hormone receptor beta multiple interactions ISO Emetine binds to and results in decreased activity of THRB protein CTD PMID:25752796 NCBI chr15:8,890,578...9,239,815
Ensembl chr15:8,890,578...9,086,282
JBrowse link
G Tia1 TIA1 cytotoxic granule-associated RNA binding protein multiple interactions ISO Emetine affects the reaction [TARDBP protein binds to TIA1 protein] CTD PMID:19765185 NCBI chr 4:118,207,845...118,238,246
Ensembl chr 4:118,207,862...118,235,218
JBrowse link
G Tial1 Tia1 cytotoxic granule-associated RNA binding protein-like 1 multiple interactions ISO Emetine affects the reaction [TARDBP protein binds to TIAR protein] CTD PMID:19765185 NCBI chr 1:199,844,854...199,865,843
Ensembl chr 1:199,844,859...199,865,548
JBrowse link
G Vegfa vascular endothelial growth factor A decreases expression ISO Emetine results in decreased expression of VEGFA protein CTD PMID:20116850 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
G Xiap X-linked inhibitor of apoptosis multiple interactions ISO Emetine inhibits the reaction [Thapsigargin affects the localization of XIAP mRNA] CTD PMID:29576526 NCBI chr  X:128,409,425...128,455,786
Ensembl chr  X:128,409,472...128,453,000
JBrowse link
eugenol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca6 ATP binding cassette subfamily A member 6 decreases expression ISO Eugenol results in decreased expression of ABCA6 mRNA CTD PMID:17374397 NCBI chr10:98,477,716...98,546,699
Ensembl chr10:98,478,067...98,544,447
JBrowse link
G Ache acetylcholinesterase multiple interactions EXP Eugenol inhibits the reaction [Chlorpyrifos results in decreased expression of ACHE protein] CTD PMID:32096903 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions
increases activity
affects localization
ISO [Eugenol co-treated with acetyleugenol] inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein]; [Eugenol co-treated with acetyleugenol] results in increased activity of AHR protein; Eugenol inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased activity of AHR protein]; Eugenol inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein]
Eugenol results in increased activity of AHR protein
Eugenol affects the localization of AHR protein
CTD PMID:17275817, PMID:22686307, PMID:29191726 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Ahrr aryl-hydrocarbon receptor repressor increases expression ISO Eugenol results in increased expression of AHRR mRNA CTD PMID:22686307 NCBI chr 1:31,603,297...31,698,329
Ensembl chr 1:31,603,297...31,698,329
JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B increases expression ISO Eugenol results in increased expression of AKR1B1 mRNA CTD PMID:20566472 NCBI chr 4:61,706,866...61,720,959
Ensembl chr 4:61,706,864...61,720,956
JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 increases expression ISO Eugenol results in increased expression of AKR1B10 mRNA CTD PMID:20566472, PMID:26198647, PMID:30806763 NCBI chr 4:61,813,265...61,830,371
Ensembl chr 4:61,771,970...61,828,657
JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 increases expression ISO Eugenol results in increased expression of AKR1C2 mRNA CTD PMID:26198647 NCBI chr17:69,388,337...69,435,160
Ensembl chr17:69,388,335...69,404,341
JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 increases expression ISO Eugenol results in increased expression of AKR1C3 mRNA CTD PMID:20566472 NCBI chr17:69,761,126...69,778,021
Ensembl chr17:69,761,118...69,778,021
JBrowse link
G Alpl alkaline phosphatase, biomineralization associated increases expression ISO Eugenol results in increased expression of ALPL mRNA CTD PMID:22083529 NCBI chr 5:156,086,496...156,141,513
Ensembl chr 5:156,086,497...156,141,537
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 multiple interactions ISO Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of APAF1 protein] CTD PMID:20434464 NCBI chr 7:31,699,309...31,784,192
Ensembl chr 7:31,699,885...31,784,192
JBrowse link
G Ar androgen receptor multiple interactions ISO Eugenol binds to and results in decreased activity of AR protein CTD PMID:20226658 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Arhgap17 Rho GTPase activating protein 17 decreases expression ISO Eugenol results in decreased expression of ARHGAP17 mRNA CTD PMID:17374397 NCBI chr 1:193,239,036...193,328,425
Ensembl chr 1:193,239,040...193,328,371
JBrowse link
G Arl4c ADP ribosylation factor like GTPase 4C increases expression ISO Eugenol results in increased expression of ARL4C mRNA CTD PMID:17374397 NCBI chr 9:95,783,651...95,787,092
Ensembl chr 9:95,786,508...95,787,094
JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO Eugenol results in increased expression of ATF3 mRNA CTD PMID:23999411 NCBI chr13:109,817,892...109,849,632
Ensembl chr13:109,817,728...109,849,632
JBrowse link
G B2m beta-2 microglobulin increases expression ISO Eugenol results in increased expression of B2M mRNA CTD PMID:17936526 NCBI chr 3:114,087,287...114,093,311
Ensembl chr 3:114,087,287...114,093,309
JBrowse link
G Bad BCL2-associated agonist of cell death multiple interactions ISO Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of BAD mRNA] CTD PMID:20434464 NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
increases expression
ISO Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of BAX mRNA]; Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of BAX protein]
Eugenol results in increased expression of BAX mRNA
CTD PMID:20434464, PMID:20537511 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
decreases expression
ISO [Eugenol results in increased activity of sulforafan] which results in decreased expression of BCL2; [sulforafan results in increased activity of Eugenol] which results in decreased expression of BCL2
Eugenol inhibits the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Croton Oil] results in increased expression of BCL2 mRNA]; Eugenol inhibits the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Croton Oil] results in increased expression of BCL2 protein]; Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of BCL2 mRNA]; Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of BCL2 protein]
Eugenol results in decreased expression of BCL2 mRNA
CTD PMID:20434464, PMID:20537511, PMID:21382956, PMID:21939359 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions ISO Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of BCL2L1 mRNA] CTD PMID:20434464 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Bclaf1 BCL2-associated transcription factor 1 decreases expression ISO Eugenol results in decreased expression of BCLAF1 mRNA CTD PMID:17374397 NCBI chr 1:15,799,753...15,828,838
Ensembl chr 1:15,782,477...15,860,624
JBrowse link
G Bdnf brain-derived neurotrophic factor increases expression ISO Eugenol results in increased expression of BDNF mRNA CTD PMID:15157811 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
JBrowse link
G Bid BH3 interacting domain death agonist multiple interactions ISO Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of BID mRNA] CTD PMID:20434464 NCBI chr 4:153,439,812...153,465,247
Ensembl chr 4:153,442,218...153,465,203
JBrowse link
G Bmp6 bone morphogenetic protein 6 increases expression ISO Eugenol results in increased expression of BMP6 mRNA CTD PMID:17374397 NCBI chr17:26,955,142...27,112,820
Ensembl chr17:26,955,142...27,112,820
JBrowse link
G Bub1 BUB1 mitotic checkpoint serine/threonine kinase decreases expression ISO Eugenol results in decreased expression of BUB1 mRNA CTD PMID:17374397 NCBI chr 3:120,373,604...120,404,910
Ensembl chr 3:120,373,604...120,404,910
JBrowse link
G Calcrl calcitonin receptor like receptor increases expression ISO Eugenol results in increased expression of CALCRL mRNA CTD PMID:17374397 NCBI chr 3:71,747,938...71,845,487
Ensembl chr 3:71,747,956...71,845,232
JBrowse link
G Casp3 caspase 3 multiple interactions
increases expression
increases activity
increases cleavage
ISO
EXP
Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of CASP3 mRNA]; Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of CASP3 protein]
Eugenol results in increased expression of CASP3 mRNA
Eugenol results in increased activity of CASP3 protein
Eugenol inhibits the reaction [Chlorpyrifos results in increased expression of CASP3 protein]; Eugenol inhibits the reaction [Doxorubicin results in increased expression of CASP3 protein]
Eugenol results in increased expression of CASP3 protein modified form
Eugenol results in increased cleavage of CASP3 protein
CTD PMID:20434464, PMID:20537511, PMID:21656368, PMID:25455450, PMID:30518369, PMID:32096903 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp7 caspase 7 increases expression ISO Eugenol results in increased expression of CASP7 mRNA CTD PMID:30518369 NCBI chr 1:277,190,557...277,242,779
Ensembl chr 1:277,190,964...277,242,774
JBrowse link
G Casp9 caspase 9 multiple interactions
increases expression
increases activity
ISO Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of CASP9 protein]
Eugenol results in increased expression of CASP9 mRNA
Eugenol results in increased activity of CASP9 protein
CTD PMID:20434464, PMID:25455450, PMID:30518369 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cat catalase increases expression
multiple interactions
ISO
EXP
Eugenol results in increased expression of CAT mRNA
Eugenol inhibits the reaction [Chlorpyrifos results in decreased expression of CAT protein]
CAT protein inhibits the reaction [[CYP2D6 protein co-treated with Copper] results in increased activity of Eugenol]
CTD PMID:15576237, PMID:20566472, PMID:32096903 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Ccl12 chemokine (C-C motif) ligand 12 increases expression ISO Eugenol results in increased expression of CCL13 mRNA CTD PMID:17936526 NCBI chr10:69,476,866...69,478,416
Ensembl chr10:69,476,775...69,478,462
JBrowse link
G Ccl19 C-C motif chemokine ligand 19 increases expression ISO Eugenol results in increased expression of CCL19 mRNA CTD PMID:17936526 NCBI chr 5:58,181,025...58,182,969
Ensembl chr 5:58,181,026...58,183,017
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression
increases secretion
decreases expression
ISO Eugenol results in increased expression of CCL2 mRNA
Eugenol results in increased secretion of CCL2 protein
Eugenol results in decreased expression of CCL2 mRNA
CTD PMID:15585374, PMID:17374397, PMID:17936526, PMID:22245253 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl20 C-C motif chemokine ligand 20 increases expression ISO Eugenol results in increased expression of CCL20 mRNA CTD PMID:30806763 NCBI chr 9:88,918,359...88,921,017
Ensembl chr 9:88,918,433...88,921,001
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 increases expression
increases secretion
ISO Eugenol results in increased expression of CCL3 mRNA
Eugenol results in increased secretion of CCL3 protein
CTD PMID:15585374, PMID:23624239 NCBI chr10:70,869,516...70,871,066
Ensembl chr10:70,869,513...70,871,066
JBrowse link
G Ccl4 C-C motif chemokine ligand 4 increases expression
increases secretion
ISO Eugenol results in increased expression of CCL4 mRNA; Eugenol results in increased expression of CCL4 protein
Eugenol results in increased secretion of CCL4 protein
CTD PMID:15585374, PMID:18353026, PMID:30806763 NCBI chr10:70,870,926...70,886,357
Ensembl chr10:70,884,531...70,886,355
JBrowse link
G Ccnb1 cyclin B1 multiple interactions EXP Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of CCNB1 mRNA] CTD PMID:19851710 NCBI chr 2:30,782,133...30,791,106
Ensembl chr 2:30,783,915...30,791,221
JBrowse link
G Ccnd1 cyclin D1 multiple interactions EXP Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of CCND1 mRNA] CTD PMID:19851710 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Ccr2 C-C motif chemokine receptor 2 decreases expression ISO Eugenol results in decreased expression of CCR2 mRNA CTD PMID:17374397
G Ccr5 C-C motif chemokine receptor 5 increases expression ISO Eugenol results in increased expression of CCR5 mRNA CTD PMID:17936526, PMID:20713136 NCBI chr 8:133,192,398...133,215,599
Ensembl chr 8:133,197,032...133,215,614
JBrowse link
G Ccr7 C-C motif chemokine receptor 7 increases expression ISO Eugenol results in increased expression of CCR7 mRNA CTD PMID:17374397 NCBI chr10:87,057,335...87,067,444
Ensembl chr10:87,057,136...87,067,456
JBrowse link
G Cd24 CD24 molecule decreases expression ISO Eugenol results in decreased expression of CD24 protein CTD PMID:31926151 NCBI chr20:48,335,540...48,340,847
Ensembl chr20:48,335,540...48,340,846
JBrowse link
G Cd274 CD274 molecule increases expression ISO Eugenol results in increased expression of CD274 protein CTD PMID:23624239 NCBI chr 1:247,519,890...247,539,659
Ensembl chr 1:247,519,939...247,537,943
JBrowse link
G Cd36 CD36 molecule decreases expression ISO Eugenol results in decreased expression of CD36 mRNA CTD PMID:17374397 NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749
JBrowse link
G Cd44 CD44 molecule (Indian blood group) decreases expression ISO Eugenol results in decreased expression of CD44 protein CTD PMID:31926151 NCBI chr 3:92,695,083...92,783,820
Ensembl chr 3:92,696,313...92,783,658
JBrowse link
G Cd86 CD86 molecule multiple interactions
increases expression
ISO [Dicumarol results in decreased activity of NQO1 protein] inhibits the reaction [Eugenol results in increased expression of CD86 protein] CTD PMID:12423654, PMID:20488241, PMID:21742781, PMID:23624239, PMID:30806763 NCBI chr11:67,060,305...67,117,990
Ensembl chr11:67,082,193...67,118,795
JBrowse link
G Cdk6 cyclin-dependent kinase 6 decreases expression ISO Eugenol results in decreased expression of CDK6 protein CTD PMID:22686307 NCBI chr 4:27,781,728...27,969,653
Ensembl chr 4:27,785,647...27,966,398
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions ISO
EXP
Eugenol inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CDKN1A protein]
Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of CDKN1A protein]
CTD PMID:19851710, PMID:20043298 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases expression ISO Eugenol results in increased expression of CDKN1B protein CTD PMID:22686307 NCBI chr 4:168,689,043...168,694,159
Ensembl chr 4:168,689,163...168,693,964
JBrowse link
G Cish cytokine inducible SH2-containing protein decreases expression ISO Eugenol results in decreased expression of CISH mRNA CTD PMID:15618236 NCBI chr 8:116,054,547...116,059,494
Ensembl chr 8:116,054,465...116,060,723
JBrowse link
G Clec4a3 C-type lectin domain family 4, member A3 decreases expression ISO Eugenol results in decreased expression of CLEC4A protein CTD PMID:23624239 NCBI chr 4:155,913,366...155,923,079
Ensembl chr 4:155,913,366...155,923,079
JBrowse link
G Creb1 cAMP responsive element binding protein 1 affects expression ISO Eugenol affects the expression of CREB1 mRNA CTD PMID:20385217 NCBI chr 9:71,229,753...71,298,994
Ensembl chr 9:71,230,108...71,293,435
JBrowse link
G Crem cAMP responsive element modulator increases expression ISO Eugenol results in increased expression of CREM mRNA CTD PMID:17374397 NCBI chr17:57,021,704...57,090,888
Ensembl chr17:57,031,766...57,090,888
JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions
decreases expression
ISO Eugenol results in decreased expression of and affects the phosphorylation of and affects the localization of CTNNB1 protein
Eugenol results in decreased expression of CTNNB1 mRNA
CTD PMID:31926151 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
JBrowse link
G Ctsl cathepsin L increases expression ISO Eugenol results in increased expression of CTSL mRNA CTD PMID:17374397 NCBI chr17:1,873,105...1,879,266
Ensembl chr17:1,872,848...1,879,279
JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 increases expression ISO Eugenol results in increased expression of CXCL1 mRNA CTD PMID:20713136 NCBI chr14:18,743,678...18,745,457
Ensembl chr14:18,743,685...18,745,457
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 increases expression
multiple interactions
ISO Eugenol results in increased expression of CXCL1 mRNA
Eugenol inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL1 mRNA]
CTD PMID:12963494, PMID:20713136 NCBI chr14:18,820,168...18,839,659
Ensembl chr14:18,820,168...18,839,595
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 increases expression ISO Eugenol results in increased expression of CXCR4 mRNA CTD PMID:20713136 NCBI chr13:45,314,952...45,318,856
Ensembl chr13:45,314,933...45,318,878
JBrowse link
G Cycs cytochrome c, somatic multiple interactions ISO Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of CYCS mRNA]; Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of CYCS protein] CTD PMID:20434464 NCBI chr 4:80,331,226...80,333,326
Ensembl chr 4:80,331,227...80,333,326
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
increases expression
decreases expression
decreases activity
ISO [CYP1A1 protein co-treated with Copper] results in increased activity of Eugenol; Eugenol inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1A1 mRNA]; Eugenol inhibits the reaction [CYP1A1 protein results in increased metabolism of and results in increased activity of 9,10-Dimethyl-1,2-benzanthracene]; Eugenol inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]
Eugenol results in increased expression of CYP1A1 mRNA
Eugenol results in decreased expression of CYP1A1 mRNA
Eugenol results in decreased activity of CYP1A1 protein
CTD PMID:15576237, PMID:17275817, PMID:20713136, PMID:22686307, PMID:29191726 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions ISO [CYP1A2 protein co-treated with Copper] results in increased activity of Eugenol CTD PMID:15576237 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions
decreases activity
ISO Eugenol inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA]; Eugenol inhibits the reaction [CYP1B1 protein results in increased metabolism of and results in increased activity of 9,10-Dimethyl-1,2-benzanthracene]
Eugenol results in decreased activity of CYP1B1 protein
CTD PMID:17275817 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 decreases expression ISO Eugenol results in decreased expression of CYP27A1 mRNA CTD PMID:20713136 NCBI chr 9:81,968,285...81,998,213
Ensembl chr 9:81,968,332...81,998,169
JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 multiple interactions
increases metabolic processing
ISO [CYP2D6 protein co-treated with Copper] results in increased activity of Eugenol; [CYP2D6 protein results in increased metabolism of Eugenol] which results in increased abundance of 2-hydroxychavicol; [Eugenol co-treated with Copper co-treated with CYP2D6 protein] results in increased abundance of 8-Hydroxy-2'-Deoxyguanosine; bathocuproine inhibits the reaction [[CYP2D6 protein co-treated with Copper] results in increased activity of Eugenol]; CAT protein inhibits the reaction [[CYP2D6 protein co-treated with Copper] results in increased activity of Eugenol]; methional inhibits the reaction [[CYP2D6 protein co-treated with Copper] results in increased activity of Eugenol] CTD PMID:15576237 NCBI chr 7:123,599,264...123,608,436
Ensembl chr 7:123,599,266...123,608,436
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions EXP
ISO
Eugenol inhibits the reaction [Thioacetamide results in increased expression of CYP2E1 protein]
[CYP2E1 protein co-treated with Copper] results in increased activity of Eugenol
CTD PMID:15576237, PMID:20036707 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Dkc1 dyskerin pseudouridine synthase 1 decreases expression ISO Eugenol results in decreased expression of DKC1 mRNA CTD PMID:17374397 NCBI chr  X:155,844,914...155,862,363
Ensembl chr  X:155,844,857...155,862,475
JBrowse link
G Dlgap5 DLG associated protein 5 decreases expression ISO Eugenol results in decreased expression of DLGAP5 mRNA CTD PMID:17374397 NCBI chr15:24,167,484...24,199,417
Ensembl chr15:24,167,486...24,199,341
JBrowse link
G Dnajb4 DnaJ heat shock protein family (Hsp40) member B4 increases expression ISO Eugenol results in increased expression of DNAJB4 mRNA CTD PMID:23999411, PMID:27965148 NCBI chr 2:257,394,692...257,425,344
Ensembl chr 2:257,394,818...257,425,242
JBrowse link
G Drd1 dopamine receptor D1 multiple interactions EXP [2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine binds to and results in increased activity of DRD1 protein] which results in increased susceptibility to Eugenol CTD PMID:9537685 NCBI chr17:11,099,736...11,104,352
Ensembl chr17:11,101,306...11,103,541
JBrowse link
G Dusp1 dual specificity phosphatase 1 increases expression ISO Eugenol results in increased expression of DUSP1 mRNA CTD PMID:30806763 NCBI chr10:16,970,642...16,973,425
Ensembl chr10:16,970,626...16,973,418
JBrowse link
G E2f1 E2F transcription factor 1 decreases expression ISO Eugenol results in decreased expression of E2F1 mRNA; Eugenol results in decreased expression of E2F1 protein CTD PMID:15574415 NCBI chr 3:150,062,895...150,073,721
Ensembl chr 3:150,047,826...150,073,721
JBrowse link
G E2f2 E2F transcription factor 2 decreases expression ISO Eugenol results in decreased expression of E2F2 mRNA; Eugenol results in decreased expression of E2F2 protein CTD PMID:15574415 NCBI chr 5:154,516,611...154,540,228
Ensembl chr 5:154,522,119...154,540,265
JBrowse link
G E2f3 E2F transcription factor 3 decreases expression ISO Eugenol results in decreased expression of E2F3 mRNA; Eugenol results in decreased expression of E2F3 protein CTD PMID:15574415 NCBI chr17:36,334,136...36,408,831
Ensembl chr17:36,334,147...36,408,831
JBrowse link
G E2f4 E2F transcription factor 4 decreases expression ISO Eugenol results in decreased expression of E2F4 mRNA CTD PMID:15574415 NCBI chr19:37,252,828...37,260,239
Ensembl chr19:37,252,843...37,260,239
JBrowse link
G E2f5 E2F transcription factor 5 decreases expression ISO Eugenol results in decreased expression of E2F5 mRNA CTD PMID:15574415 NCBI chr 2:88,350,764...88,366,913
Ensembl chr 2:88,351,361...88,366,115
JBrowse link
G E2f6 E2F transcription factor 6 increases expression ISO Eugenol results in increased expression of E2F6 mRNA CTD PMID:15574415 NCBI chr 6:42,092,513...42,108,692
Ensembl chr 6:42,092,467...42,108,702
JBrowse link
G Egfr epidermal growth factor receptor decreases expression
increases expression
ISO Eugenol results in decreased expression of EGFR protein
Eugenol results in increased expression of EGFR mRNA
CTD PMID:15618236 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
JBrowse link
G Egr1 early growth response 1 multiple interactions ISO [[Eugenol results in increased activity of OLFR73 protein] which results in increased abundance of Cyclic AMP] which results in increased expression of EGR1 mRNA CTD PMID:12767924 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
JBrowse link
G Egr2 early growth response 2 decreases expression ISO Eugenol results in decreased expression of EGR2 mRNA CTD PMID:17374397 NCBI chr20:22,452,170...22,461,018
Ensembl chr20:22,454,463...22,459,025
JBrowse link
G Emb embigin decreases expression ISO Eugenol results in decreased expression of EMB mRNA CTD PMID:17374397 NCBI chr 2:49,682,763...49,733,475
Ensembl chr 2:49,682,754...49,732,253
JBrowse link
G Epcam epithelial cell adhesion molecule decreases expression ISO Eugenol results in decreased expression of EPCAM protein
Eugenol results in decreased expression of EPCAM mRNA; Eugenol results in decreased expression of EPCAM protein
CTD PMID:31926151 NCBI chr 6:11,282,194...11,308,870
Ensembl chr 6:11,281,964...11,298,216
JBrowse link
G Esr1 estrogen receptor 1 affects binding
multiple interactions
ISO Eugenol binds to ESR1 protein
Eugenol inhibits the reaction [Estradiol binds to ESR1 protein]
CTD PMID:12495555 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Esr2 estrogen receptor 2 affects binding
multiple interactions
ISO Eugenol binds to ESR2 protein
Eugenol inhibits the reaction [Estradiol binds to ESR2 protein]
CTD PMID:12495555 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
JBrowse link
G F13a1 coagulation factor XIII A1 chain decreases expression ISO Eugenol results in decreased expression of F13A1 mRNA CTD PMID:17374397 NCBI chr17:28,504,650...28,680,015
Ensembl chr17:28,504,623...28,680,362
JBrowse link
G Fasn fatty acid synthase decreases expression ISO Eugenol results in decreased expression of FASN mRNA CTD PMID:21870829 NCBI chr10:109,987,735...110,005,901
Ensembl chr10:109,987,735...110,005,901
JBrowse link
G Fbxo9 f-box protein 9 decreases expression ISO Eugenol results in decreased expression of FBXO9 mRNA CTD PMID:17374397 NCBI chr 8:85,388,331...85,413,896
Ensembl chr 8:85,388,333...85,413,484
JBrowse link
G Fcgr2b Fc fragment of IgG receptor IIb increases expression ISO Eugenol results in increased expression of FCGR2B mRNA CTD PMID:17374397 NCBI chr13:89,329,298...89,343,916
Ensembl chr13:89,327,794...89,433,815
JBrowse link
G Fech ferrochelatase increases expression ISO Eugenol results in increased expression of FECH mRNA CTD PMID:20566472 NCBI chr18:59,941,992...59,975,192
Ensembl chr18:59,941,992...59,975,192
JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 multiple interactions EXP Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of FLT1 mRNA] CTD PMID:20434464 NCBI chr12:9,033,993...9,205,886
Ensembl chr12:9,034,308...9,205,905
JBrowse link
G Fosl2 FOS like 2, AP-1 transcription factor subunit increases expression ISO Eugenol results in increased expression of FOSL2 mRNA CTD PMID:17374397 NCBI chr 6:25,598,936...25,616,995
Ensembl chr 6:25,598,936...25,616,995
JBrowse link
G Ftl1 ferritin light chain 1 increases expression ISO Eugenol results in increased expression of FTL mRNA CTD PMID:20566472 NCBI chr 1:101,448,190...101,450,034
Ensembl chr 1:101,448,346...101,449,829
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase increases expression ISO Eugenol results in increased expression of G6PD mRNA CTD PMID:20566472 NCBI chr  X:156,274,800...156,293,935
Ensembl chr  X:156,274,800...156,293,926
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha multiple interactions EXP Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of GADD45A mRNA] CTD PMID:19851710 NCBI chr 4:97,782,512...97,784,814
Ensembl chr 4:97,782,512...97,784,842
JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible, beta increases expression ISO Eugenol results in increased expression of GADD45B mRNA CTD PMID:15618236 NCBI chr 7:11,646,283...11,648,338
Ensembl chr 7:11,646,269...11,648,322
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression ISO Eugenol results in increased expression of GCLC mRNA CTD PMID:20566472, PMID:26198647, PMID:30806763 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO Eugenol results in increased expression of GCLM mRNA CTD PMID:20566472, PMID:26198647, PMID:27965148, PMID:30806763 NCBI chr 2:225,827,504...225,847,876
Ensembl chr 2:225,827,504...225,847,874
JBrowse link
G Gpat3 glycerol-3-phosphate acyltransferase 3 increases expression ISO Eugenol results in increased expression of GPAT3 mRNA CTD PMID:26198647 NCBI chr14:10,343,287...10,396,565
Ensembl chr14:10,343,282...10,395,047
JBrowse link
G Gpx3 glutathione peroxidase 3 increases expression ISO Eugenol results in increased expression of GPX3 mRNA CTD PMID:20566472 NCBI chr10:40,247,436...40,255,423
Ensembl chr10:40,247,436...40,255,422
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta increases expression ISO Eugenol results in increased expression of GSK3B mRNA CTD PMID:17374397 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Gsr glutathione-disulfide reductase increases expression ISO Eugenol results in increased expression of GSR mRNA CTD PMID:20566472 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Gsta1 glutathione S-transferase alpha 1 decreases activity ISO Eugenol analog results in decreased activity of GSTA1 protein CTD PMID:8620581 NCBI chr 9:27,366,404...27,381,004
Ensembl chr 9:27,368,272...27,452,902
JBrowse link
G Gsta2 glutathione S-transferase alpha 2 increases expression
decreases activity
EXP Eugenol results in increased expression of GSTA2 protein
Eugenol analog results in decreased activity of GSTA2 protein
CTD PMID:8406240, PMID:8620581 NCBI chr 8:85,640,081...85,645,621 JBrowse link
G Gsta3 glutathione S-transferase alpha 3 decreases activity EXP Eugenol analog results in decreased activity of GSTA3 protein CTD PMID:8620581 NCBI chr 9:27,357,490...27,417,023
Ensembl chr 9:27,402,381...27,417,023
JBrowse link
G Gstm1 glutathione S-transferase mu 1 decreases activity ISO
EXP
Eugenol analog results in decreased activity of GSTM1 protein CTD PMID:8620581 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G Gstm2 glutathione S-transferase mu 2 decreases activity EXP Eugenol analog results in decreased activity of GSTM2 protein CTD PMID:8620581 NCBI chr 2:210,778,041...210,782,807
Ensembl chr 2:210,720,704...210,782,856
JBrowse link
G Gstp1 glutathione S-transferase pi 1 decreases activity ISO
EXP
Eugenol analog results in decreased activity of GSTP1 protein CTD PMID:8620581 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G Heatr5b HEAT repeat containing 5B decreases expression ISO Eugenol results in decreased expression of HEATR5B mRNA CTD PMID:17374397 NCBI chr 6:1,330,314...1,410,339
Ensembl chr 6:1,330,314...1,410,339
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha increases expression ISO Eugenol results in increased expression of HIF1A mRNA CTD PMID:20713136 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase decreases expression ISO Eugenol results in decreased expression of HMGCR mRNA CTD PMID:21870829 NCBI chr 2:27,480,224...27,500,654
Ensembl chr 2:27,480,226...27,500,654
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO Eugenol results in increased expression of HMOX1 mRNA CTD PMID:20566472, PMID:20713136, PMID:23445166, PMID:26244607, PMID:30806763 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hnrnpa3 heterogeneous nuclear ribonucleoprotein A3 decreases expression ISO Eugenol results in decreased expression of HNRNPA3 mRNA CTD PMID:17374397 NCBI chr 3:62,481,222...62,491,356
Ensembl chr 3:62,481,323...62,487,227
JBrowse link
G Hras HRas proto-oncogene, GTPase decreases expression ISO Eugenol results in decreased expression of HRAS protein CTD PMID:20537511 NCBI chr 1:214,178,404...214,181,841
Ensembl chr 1:214,178,407...214,181,686
JBrowse link
G Hsph1 heat shock protein family H (Hsp110) member 1 increases expression ISO Eugenol results in increased expression of HSPH1 mRNA CTD PMID:23999411 NCBI chr12:6,322,685...6,341,898
Ensembl chr12:6,322,668...6,341,902
JBrowse link
G Ibsp integrin-binding sialoprotein decreases expression ISO Eugenol results in decreased expression of IBSP mRNA; Eugenol results in decreased expression of IBSP protein CTD PMID:21706355 NCBI chr14:6,801,200...6,813,987
Ensembl chr14:6,801,204...6,813,945
JBrowse link
G Icam1 intercellular adhesion molecule 1 increases expression ISO Eugenol results in increased expression of ICAM1 mRNA; Eugenol results in increased expression of ICAM1 protein CTD PMID:30806763 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Idi1 isopentenyl-diphosphate delta isomerase 1 decreases expression ISO Eugenol results in decreased expression of IDI1 mRNA CTD PMID:17374397 NCBI chr17:57,976,266...57,984,036
Ensembl chr17:57,976,268...57,984,036
JBrowse link
G Ifng interferon gamma increases secretion
multiple interactions
ISO Eugenol results in increased secretion of IFNG protein
[Methoxychlor co-treated with Eugenol] results in increased expression of IFNG protein; [Parathion co-treated with Eugenol] results in increased expression of IFNG protein
CTD PMID:20920556, PMID:22245253 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta multiple interactions EXP Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of IKBKB protein] CTD PMID:19851710 NCBI chr16:74,177,233...74,230,809
Ensembl chr16:74,177,215...74,230,815
JBrowse link
G Il10 interleukin 10 multiple interactions ISO [Eugenol co-treated with Acetylcysteine] inhibits the reaction [Nicotine results in decreased secretion of IL10 protein]; Eugenol inhibits the reaction [Nicotine results in decreased expression of IL10 mRNA] CTD PMID:21237301 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il12a interleukin 12A multiple interactions ISO Eugenol inhibits the reaction [Nicotine results in increased secretion of [IL12A protein co-treated with IL12B protein]] CTD PMID:21237301 NCBI chr 2:165,076,945...165,083,996
Ensembl chr 2:165,076,607...165,084,318
JBrowse link
G Il12b interleukin 12B multiple interactions ISO Eugenol inhibits the reaction [Nicotine results in increased expression of IL12B mRNA]; Eugenol inhibits the reaction [Nicotine results in increased secretion of [IL12A protein co-treated with IL12B protein]] CTD PMID:21237301 NCBI chr10:30,034,447...30,048,774
Ensembl chr10:30,038,709...30,048,085
JBrowse link
G Il16 interleukin 16 multiple interactions
increases secretion
ISO Eugenol results in increased expression of and results in increased secretion of IL16 protein
Eugenol results in increased secretion of IL16 protein
CTD PMID:23624239, PMID:30806763 NCBI chr 1:145,781,923...145,881,538
Ensembl chr 1:145,781,928...145,870,912
JBrowse link
G Il18 interleukin 18 increases expression ISO Eugenol results in increased expression of IL18 protein CTD PMID:23063874 NCBI chr 8:55,009,666...55,016,286
Ensembl chr 8:54,993,859...55,016,299
JBrowse link
G Il1a interleukin 1 alpha increases expression ISO Eugenol results in increased expression of IL1A mRNA CTD PMID:30806763 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases expression
decreases expression
ISO [Eugenol results in increased activity of sulforafan] which results in decreased expression of IL1B; [sulforafan results in increased activity of Eugenol] which results in decreased expression of IL1B; Eugenol inhibits the reaction [[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL1B protein]; Eugenol inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of IL1B protein]; Eugenol inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]
Eugenol results in increased expression of IL1B mRNA
Eugenol inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; Eugenol inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein]
Eugenol results in decreased expression of IL1B mRNA
CTD PMID:12963494, PMID:17509409, PMID:20713136, PMID:21382956, PMID:21807015, PMID:21939359 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il1r2 interleukin 1 receptor type 2 increases expression ISO Eugenol results in increased expression of IL1R2 mRNA CTD PMID:20713136, PMID:30806763 NCBI chr 9:46,840,646...46,881,241
Ensembl chr 9:46,840,992...46,881,264
JBrowse link
G Il2 interleukin 2 increases expression
increases secretion
ISO Eugenol results in increased expression of IL2 protein
Eugenol results in increased secretion of IL2 protein
CTD PMID:22245253, PMID:22381623 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854
JBrowse link
G Il4r interleukin 4 receptor increases expression ISO Eugenol results in increased expression of IL4RA protein CTD PMID:22381623 NCBI chr 1:196,942,343...196,967,221
Ensembl chr 1:196,942,364...196,967,220
JBrowse link
G Il6 interleukin 6 multiple interactions
increases secretion
increases expression
ISO
EXP
Eugenol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased secretion of IL6 protein]
Eugenol results in increased secretion of IL6 protein
Eugenol inhibits the reaction [Thioacetamide results in increased activity of IL6 protein]
Eugenol results in increased expression of IL6 mRNA
CTD PMID:20036707, PMID:20043298, PMID:21870829, PMID:22245253 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Il7r interleukin 7 receptor increases expression ISO Eugenol results in increased expression of IL7R mRNA CTD PMID:20713136
G Inhba inhibin subunit beta A decreases expression ISO Eugenol results in decreased expression of INHBA mRNA CTD PMID:15618236 NCBI chr17:51,894,869...51,919,998
Ensembl chr17:51,898,217...51,912,496
JBrowse link
G Ipcef1 interaction protein for cytohesin exchange factors 1 decreases expression ISO Eugenol results in decreased expression of IPCEF1 mRNA CTD PMID:17374397 NCBI chr 1:43,563,457...43,743,424
Ensembl chr 1:43,567,842...43,638,161
JBrowse link
G Itga6 integrin subunit alpha 6 increases expression ISO Eugenol results in increased expression of ITGA6 mRNA CTD PMID:17936526 NCBI chr 3:58,442,904...58,515,124
Ensembl chr 3:58,443,101...58,515,124
JBrowse link
G Itgb1 integrin subunit beta 1 increases expression ISO Eugenol results in increased expression of ITGB1 mRNA CTD PMID:17936526 NCBI chr19:61,677,512...61,725,537
Ensembl chr19:61,677,542...61,725,535
JBrowse link
G Kcna5 potassium voltage-gated channel subfamily A member 5 decreases activity ISO Eugenol results in decreased activity of KCNA5 protein CTD PMID:17720863 NCBI chr 4:159,077,195...159,079,003
Ensembl chr 4:159,077,195...159,079,003
JBrowse link
G Kcnj2 potassium inwardly-rectifying channel, subfamily J, member 2 decreases expression ISO Eugenol results in decreased expression of KCNJ2 mRNA CTD PMID:17374397 NCBI chr10:99,429,337...99,442,520
Ensembl chr10:99,437,436...99,439,114
JBrowse link
G Kif23 kinesin family member 23 decreases expression ISO Eugenol results in decreased expression of KIF23 mRNA CTD PMID:17374397 NCBI chr 8:66,866,043...66,893,241
Ensembl chr 8:66,866,082...66,893,196
JBrowse link
G LOC100912605 olfactory receptor 5D14-like multiple interactions
increases activity
affects binding
ISO [[Eugenol results in increased activity of OLFR73 protein] which results in increased abundance of Cyclic AMP] which results in increased expression of EGR1 mRNA; [Eugenol binds to and results in increased activity of OLFR73 protein] which results in increased abundance of Cyclic AMP; [Eugenol binds to and results in increased activity of OLFR73 protein] which results in increased transport of Calcium; [Eugenol binds to OLFR73 protein] which results in increased transport of Calcium; [Eugenol results in increased activity of OLFR73 protein] which results in increased abundance of Cyclic AMP; Eugenol binds to and results in increased activity of OLFR73 protein; isomethyleugenol inhibits the reaction [[Eugenol binds to OLFR73 protein] which results in increased transport of Calcium] CTD PMID:12767924, PMID:14685265, PMID:15716417, PMID:19723634 NCBI chr 3:76,255,179...76,256,129
Ensembl chr 3:76,255,179...76,256,129
JBrowse link
G Maff MAF bZIP transcription factor F increases expression ISO Eugenol results in increased expression of MAFF mRNA CTD PMID:20566472 NCBI chr 7:120,580,743...120,592,095
Ensembl chr 7:120,580,743...120,592,095
JBrowse link
G Mafg MAF bZIP transcription factor G increases expression ISO Eugenol results in increased expression of MAFG mRNA CTD PMID:20566472 NCBI chr10:109,802,877...109,811,476
Ensembl chr10:109,806,159...109,811,323
JBrowse link
G Mafk MAF bZIP transcription factor K increases expression ISO Eugenol results in increased expression of MAFK mRNA CTD PMID:20566472 NCBI chr12:16,923,989...16,934,706
Ensembl chr12:16,923,990...16,934,706
JBrowse link
G Mcts1 MCTS1, re-initiation and release factor decreases expression ISO Eugenol results in decreased expression of MCTS1 mRNA CTD PMID:17374397 NCBI chr  X:124,894,269...124,906,129
Ensembl chr  X:124,894,466...124,906,162
JBrowse link
G Me1 malic enzyme 1 increases expression ISO Eugenol results in increased expression of ME1 mRNA CTD PMID:20566472 NCBI chr 8:94,256,830...94,368,834
Ensembl chr 8:94,256,839...94,368,834
JBrowse link
G Mgst1 microsomal glutathione S-transferase 1 increases expression ISO Eugenol results in increased expression of MGST1 mRNA CTD PMID:20566472 NCBI chr 4:172,119,382...172,134,609
Ensembl chr 4:172,119,331...172,134,607
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions
decreases expression
EXP
ISO
Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of and results in increased activity of MMP2 protein]; Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of MMP2 mRNA]
Eugenol results in decreased expression of MMP2 mRNA
CTD PMID:20434464, PMID:30518369 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
decreases expression
EXP
ISO
Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of and results in increased activity of MMP9 protein]; Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of MMP9 mRNA]
Eugenol results in decreased expression of MMP9 mRNA
CTD PMID:20434464, PMID:30518369 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Mpo myeloperoxidase multiple interactions EXP Eugenol inhibits the reaction [Thioacetamide results in increased activity of MPO protein] CTD PMID:20036707 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
JBrowse link
G Mrpl35 mitochondrial ribosomal protein L35 decreases expression ISO Eugenol results in decreased expression of MRPL35 mRNA CTD PMID:17374397 NCBI chr 4:99,738,792...99,749,665
Ensembl chr 4:99,738,792...99,746,560
JBrowse link
G Ms4a7 membrane spanning 4-domains A7 increases expression ISO Eugenol results in increased expression of MS4A7 mRNA CTD PMID:17374397 NCBI chr 1:227,490,777...227,506,819
Ensembl chr 1:227,490,777...227,506,822
JBrowse link
G Mt3 metallothionein 3 increases expression ISO Eugenol results in increased expression of MT3 mRNA CTD PMID:15157811 NCBI chr19:11,324,708...11,326,112
Ensembl chr19:11,324,698...11,326,139
JBrowse link
G Mxd1 max dimerization protein 1 increases expression ISO Eugenol results in increased expression of MXD1 mRNA CTD PMID:20713136 NCBI chr 4:118,451,752...118,472,150
Ensembl chr 4:118,449,882...118,472,179
JBrowse link
G Myb MYB proto-oncogene, transcription factor decreases expression ISO Eugenol results in decreased expression of MYB mRNA CTD PMID:17374397 NCBI chr 1:16,658,178...16,690,135
Ensembl chr 1:16,659,442...16,687,817
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor multiple interactions ISO Eugenol inhibits the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Croton Oil] results in increased expression of MYC protein] CTD PMID:20537511 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Nampt nicotinamide phosphoribosyltransferase increases expression ISO Eugenol results in increased expression of NAMPT mRNA CTD PMID:17374397 NCBI chr 6:52,122,085...52,156,473
Ensembl chr 6:52,122,085...52,156,472
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 affects expression
multiple interactions
ISO Eugenol affects the expression of NFE2L2 protein
Eugenol promotes the reaction [NFE2L2 protein results in increased expression of NQO1 mRNA]
CTD PMID:17275817 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions
affects expression
ISO
EXP
Eugenol inhibits the reaction [TNF protein results in increased activity of [NFKB1 protein binds to RELA protein]]
Eugenol affects the expression of NFKB1 mRNA
Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of NFKB1 mRNA]; Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of NFKB1 protein]
CTD PMID:10871845, PMID:19851710, PMID:20385217 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions EXP
ISO
Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of NFKBIA mRNA]; Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of NFKBIA protein]; Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of NFKBIA protein modified form]
Eugenol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of NFKBIA protein modified form]; Eugenol inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased degradation of NFKBIA protein]
CTD PMID:12963494, PMID:19851710, PMID:20043298 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO Eugenol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of NOS2 protein]; Eugenol inhibits the reaction [Nicotine results in increased expression of NOS2 mRNA]; Eugenol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein] CTD PMID:20043298, PMID:21237301 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Notch1 notch receptor 1 decreases expression ISO Eugenol results in decreased expression of NOTCH1 protein
Eugenol results in decreased expression of NOTCH1 mRNA; Eugenol results in decreased expression of NOTCH1 protein
CTD PMID:31926151 NCBI chr 3:3,905,562...3,951,015
Ensembl chr 3:3,905,453...3,951,025
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression
increases activity
multiple interactions
ISO Eugenol results in increased expression of NQO1 mRNA; Eugenol results in increased expression of NQO1 protein
Eugenol results in increased activity of NQO1 protein
[Dicumarol results in decreased activity of NQO1 protein] inhibits the reaction [Eugenol results in increased expression of CD86 protein]; Eugenol promotes the reaction [NFE2L2 protein results in increased expression of NQO1 mRNA]
CTD PMID:17275817, PMID:20566472, PMID:21742781 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases expression ISO Eugenol results in increased expression of NR1I2 mRNA CTD PMID:29933105 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
G Nup88 nucleoporin 88 increases expression ISO Eugenol results in increased expression of NUP88 mRNA CTD PMID:17374397 NCBI chr10:57,581,828...57,606,171
Ensembl chr10:57,581,828...57,606,171
JBrowse link
G P2rx3 purinergic receptor P2X 3 multiple interactions EXP Eugenol inhibits the reaction [P2RX3 protein affects the activity of Adenosine Triphosphate] CTD PMID:19967073 NCBI chr 3:72,403,992...72,447,801
Ensembl chr 3:72,403,993...72,447,801
JBrowse link
G Paics phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase decreases expression ISO Eugenol results in decreased expression of PAICS mRNA CTD PMID:17374397 NCBI chr14:33,563,884...33,580,944
Ensembl chr14:33,563,886...33,580,566
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO Eugenol affects the reaction [Methylnitronitrosoguanidine affects the cleavage of PARP1 protein] CTD PMID:20434464 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions ISO
EXP
Eugenol inhibits the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PCNA protein]
Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of PCNA mRNA]; Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of PCNA protein]
CTD PMID:19851710, PMID:20043298 NCBI chr 3:124,880,698...124,884,570
Ensembl chr 3:124,880,698...124,884,570
JBrowse link
G Pde4b phosphodiesterase 4B increases expression ISO Eugenol results in increased expression of PDE4B mRNA CTD PMID:17374397 NCBI chr 5:121,759,236...122,136,814
Ensembl chr 5:121,952,977...122,136,814
JBrowse link
G Pgd phosphogluconate dehydrogenase increases expression ISO Eugenol results in increased expression of PGD mRNA CTD PMID:20566472 NCBI chr 5:165,966,128...165,982,327 JBrowse link
G Picalm phosphatidylinositol binding clathrin assembly protein increases expression ISO Eugenol results in increased expression of PICALM mRNA CTD PMID:17374397 NCBI chr 1:154,377,229...154,458,966
Ensembl chr 1:154,377,247...154,458,425
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 increases expression EXP
ISO
Eugenol results in increased expression of PIK3R1 mRNA CTD PMID:20724125, PMID:21870829 NCBI chr 2:31,742,326...31,826,882
Ensembl chr 2:31,745,088...31,826,867
JBrowse link
G Plat plasminogen activator, tissue type increases expression ISO Eugenol results in increased expression of PLAT mRNA CTD PMID:17374397 NCBI chr16:74,098,263...74,122,897
Ensembl chr16:74,098,260...74,122,889
JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 increases expression ISO Eugenol results in increased expression of PMAIP1 mRNA CTD PMID:20713136 NCBI chr18:62,159,128...62,179,635
Ensembl chr18:62,174,670...62,181,102
JBrowse link
G Pou5f1 POU class 5 homeobox 1 decreases expression ISO Eugenol results in decreased expression of POU5F1 protein
Eugenol results in decreased expression of POU5F1 mRNA; Eugenol results in decreased expression of POU5F1 protein
CTD PMID:31926151 NCBI chr20:3,747,231...3,751,994
Ensembl chr20:3,747,221...3,751,994
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions
increases expression
ISO Eugenol analog binds to and results in increased activity of PPARG protein
Eugenol results in increased expression of PPARG mRNA
2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [Eugenol analog binds to and results in increased activity of PPARG protein]; Eugenol analog binds to and results in increased activity of PPARG protein
CTD PMID:20064974, PMID:21870829 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Ppbp pro-platelet basic protein multiple interactions
increases expression
ISO Eugenol results in increased expression of and results in increased secretion of PPBP protein
Eugenol results in increased expression of PPBP mRNA
CTD PMID:23624239 NCBI chr14:18,852,433...18,853,237
Ensembl chr14:18,851,954...18,853,315
JBrowse link
G Prdx3 peroxiredoxin 3 decreases expression ISO Eugenol results in decreased expression of PRDX3 mRNA CTD PMID:17374397 NCBI chr 1:282,238,774...282,251,193
Ensembl chr 1:282,238,773...282,251,257
JBrowse link
G Ptger3 prostaglandin E receptor 3 decreases expression ISO Eugenol results in decreased expression of PTGER3 mRNA CTD PMID:17374397 NCBI chr 2:263,895,093...263,979,682
Ensembl chr 2:263,895,241...263,979,698
JBrowse link
G Ptgr1 prostaglandin reductase 1 increases expression ISO Eugenol results in increased expression of PTGR1 mRNA CTD PMID:20566472 NCBI chr 5:76,110,746...76,129,361
Ensembl chr 5:76,110,738...76,129,441
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
increases expression
decreases expression
ISO
EXP
Eugenol inhibits the reaction [[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PTGS2 mRNA]; Eugenol inhibits the reaction [[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PTGS2 protein]; Eugenol inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]
Eugenol results in increased expression of PTGS2 mRNA
Eugenol results in decreased expression of PTGS2 mRNA
Eugenol inhibits the reaction [Thioacetamide results in increased expression of PTGS2 protein]; Eugenol inhibits the reaction [Thioacetamide results in increased expression of PTGS2]
Eugenol inhibits the reaction [[Lipopolysaccharides results in increased expression of and results in increased activity of PTGS2 protein] which results in increased abundance of Dinoprostone]; Eugenol inhibits the reaction [[Lipopolysaccharides results in increased expression of and results in increased activity of PTGS2 protein] which results in increased metabolism of Arachidonic Acid]; Eugenol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of PTGS2 protein]; Eugenol inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased activity of PTGS2 protein]; Eugenol inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; Eugenol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]
CTD PMID:12757841, PMID:16101137, PMID:17509409, PMID:20036707, PMID:20043298, PMID:21807015, PMID:21939359, PMID:30806763 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Rb1 RB transcriptional corepressor 1 decreases expression ISO Eugenol results in decreased expression of RB1 protein CTD PMID:22686307 NCBI chr15:55,081,582...55,209,060
Ensembl chr15:55,083,140...55,209,342
JBrowse link
G Reck reversion-inducing-cysteine-rich protein with kazal motifs multiple interactions EXP Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of RECK mRNA]; Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of RECK protein] CTD PMID:20434464 NCBI chr 5:59,348,568...59,415,169
Ensembl chr 5:59,348,639...59,415,135
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO
EXP
Eugenol inhibits the reaction [TNF protein results in increased activity of [NFKB1 protein binds to RELA protein]]
Eugenol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of RELA protein]
Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of RELA mRNA]; Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of RELA protein]
CTD PMID:10871845, PMID:19851710, PMID:20043298 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G RGD1311164 similar to DNA segment, Chr 6, Wayne State University 163, expressed decreases expression ISO Eugenol results in decreased expression of C12ORF4 mRNA CTD PMID:17374397 NCBI chr 4:159,483,089...159,518,387
Ensembl chr 4:159,483,131...159,515,447
JBrowse link
G Rgs1 regulator of G-protein signaling 1 increases expression ISO Eugenol results in increased expression of RGS1 mRNA CTD PMID:17374397, PMID:20713136 NCBI chr13:61,066,196...61,070,772
Ensembl chr13:61,066,153...61,070,599
JBrowse link
G Rpl27a ribosomal protein L27a increases expression ISO Eugenol results in increased expression of RPL27A mRNA CTD PMID:17374397 NCBI chr 1:174,132,798...174,135,816
Ensembl chr 1:174,132,798...174,135,816
JBrowse link
G Rrm2b ribonucleotide reductase regulatory TP53 inducible subunit M2B increases expression ISO Eugenol results in increased expression of RRM2B mRNA CTD PMID:21704725 NCBI chr 7:76,750,045...76,780,817
Ensembl chr 7:76,750,050...76,780,817
JBrowse link
G Sat1 spermidine/spermine N1-acetyl transferase 1 increases expression ISO Eugenol results in increased expression of SAT1 mRNA CTD PMID:17374397 NCBI chr  X:43,626,480...43,629,767
Ensembl chr  X:43,625,169...43,629,765
JBrowse link
G Sdc2 syndecan 2 increases expression ISO Eugenol results in increased expression of SDC2 mRNA CTD PMID:17374397 NCBI chr 7:71,572,731...71,686,139
Ensembl chr 7:71,572,941...71,686,044
JBrowse link
G Septin11 septin 11 decreases expression ISO Eugenol results in decreased expression of SEPTIN11 mRNA CTD PMID:17374397 NCBI chr14:16,369,544...16,405,645
Ensembl chr14:16,369,544...16,452,998
JBrowse link
G Serpinb3 serpin family B member 3 increases expression ISO Eugenol results in increased expression of SERPINB3 mRNA CTD PMID:30806763 NCBI chr13:27,186,701...27,193,211
Ensembl chr13:27,187,130...27,192,592
JBrowse link
G Slamf1 signaling lymphocytic activation molecule family member 1 decreases expression ISO Eugenol results in decreased expression of SLAMF1 mRNA CTD PMID:20713136 NCBI chr13:90,184,545...90,219,170
Ensembl chr13:90,184,569...90,219,217
JBrowse link
G Slc16a10 solute carrier family 16 member 10 increases expression ISO Eugenol results in increased expression of SLC16A10 mRNA CTD PMID:17374397 NCBI chr20:45,138,433...45,260,155
Ensembl chr20:45,143,453...45,260,119
JBrowse link
G Slc2a3 solute carrier family 2 member 3 increases expression ISO Eugenol results in increased expression of SLC2A3 mRNA CTD PMID:17374397 NCBI chr 4:155,549,991...155,626,018
Ensembl chr 4:155,408,233...155,631,856
JBrowse link
G Slc2a4 solute carrier family 2 member 4 increases expression ISO
EXP
Eugenol results in increased expression of SLC2A4 mRNA CTD PMID:20724125, PMID:21870829 NCBI chr10:56,552,921...56,558,562
Ensembl chr10:56,552,983...56,558,487
JBrowse link
G Slc7a11 solute carrier family 7 member 11 increases expression ISO Eugenol results in increased expression of SLC7A11 mRNA CTD PMID:26198647, PMID:30806763 NCBI chr 2:139,453,774...139,528,479
Ensembl chr 2:139,453,774...139,528,162
JBrowse link
G Sod1 superoxide dismutase 1 increases expression
decreases expression
multiple interactions
ISO Eugenol results in increased expression of SOD1 mRNA
Eugenol results in decreased expression of SOD1 mRNA; Eugenol results in decreased expression of SOD1 protein
Acetylcysteine promotes the reaction [Eugenol results in decreased expression of SOD1 mRNA]; Glutathione promotes the reaction [Eugenol results in decreased expression of SOD1 mRNA]
CTD PMID:16101137, PMID:20566472 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Sod2 superoxide dismutase 2 increases expression
decreases expression
multiple interactions
ISO Eugenol results in increased expression of SOD2 mRNA
Eugenol results in decreased expression of SOD2 mRNA; Eugenol results in decreased expression of SOD2 protein
Acetylcysteine promotes the reaction [Eugenol results in decreased expression of SOD2 mRNA]; Glutathione promotes the reaction [Eugenol results in decreased expression of SOD2 mRNA]
CTD PMID:16101137, PMID:20566472 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Sod3 superoxide dismutase 3 increases expression ISO Eugenol results in increased expression of SOD3 mRNA CTD PMID:20566472 NCBI chr14:60,958,583...60,971,143
Ensembl chr14:60,958,592...60,964,324
JBrowse link
G Sqstm1 sequestosome 1 increases expression ISO Eugenol results in increased expression of SQSTM1 mRNA CTD PMID:26198647 NCBI chr10:35,704,728...35,716,316
Ensembl chr10:35,704,730...35,716,294
JBrowse link
G Srxn1 sulfiredoxin 1 increases expression ISO Eugenol results in increased expression of SRXN1 mRNA CTD PMID:20566472, PMID:26198647 NCBI chr 3:147,608,850...147,614,410
Ensembl chr 3:147,609,095...147,632,801
JBrowse link
G Stat1 signal transducer and activator of transcription 1 decreases expression ISO Eugenol results in decreased expression of STAT1 mRNA CTD PMID:17374397 NCBI chr 9:54,287,540...54,327,958
Ensembl chr 9:54,287,541...54,484,533
JBrowse link
G Stat4 signal transducer and activator of transcription 4 increases expression ISO Eugenol results in increased expression of STAT4 mRNA CTD PMID:17374397 NCBI chr 9:54,340,649...54,457,753
Ensembl chr 9:54,287,541...54,484,533
JBrowse link
G Stat5b signal transducer and activator of transcription 5B increases expression ISO Eugenol results in increased expression of STAT5B mRNA CTD PMID:17374397 NCBI chr10:88,686,207...88,712,313
Ensembl chr10:88,686,207...88,754,829
JBrowse link
G Sult1c3 sulfotransferase family 1C member 3 increases sulfation ISO SULT1C1 protein results in increased sulfation of Eugenol CTD PMID:9560327 NCBI chr 9:4,931,038...4,978,847
Ensembl chr 9:4,930,818...4,978,892
JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 multiple interactions EXP Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of TIMP2 mRNA]; Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of TIMP2 protein] CTD PMID:20434464 NCBI chr10:107,338,465...107,386,072
Ensembl chr10:107,338,465...107,386,072
JBrowse link
G Tlr4 toll-like receptor 4 increases expression ISO Eugenol results in increased expression of TLR4 mRNA CTD PMID:17936526 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
affects expression
ISO
EXP
Eugenol inhibits the reaction [[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of TNF protein]; Eugenol inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of TNF protein]; Eugenol inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; Eugenol inhibits the reaction [TNF protein results in increased activity of [NFKB1 protein binds to RELA protein]]
Eugenol results in increased expression of TNF mRNA
Eugenol affects the expression of TNF mRNA
Eugenol inhibits the reaction [Chlorpyrifos results in increased expression of TNF protein]; Eugenol inhibits the reaction [Thioacetamide results in increased activity of TNF protein]
[Methoxychlor co-treated with Eugenol] results in increased expression of TNF protein; [Parathion co-treated with Eugenol] results in increased expression of TNF protein; Eugenol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased secretion of TNF protein]; Eugenol inhibits the reaction [Bacterial Toxins results in increased secretion of TNF protein]; Eugenol inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; Eugenol inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; Eugenol inhibits the reaction [Nicotine results in increased expression of TNF mRNA]; Eugenol inhibits the reaction [Nicotine results in increased secretion of TNF protein]
CTD PMID:10871845, PMID:12963494, PMID:17509409, PMID:20036707, PMID:20043298, PMID:20385217, PMID:20639367, PMID:20920556, PMID:21237301, PMID:21807015, PMID:21870829, PMID:30806763, PMID:32096903 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfaip3 TNF alpha induced protein 3 increases expression ISO Eugenol results in increased expression of TNFAIP3 mRNA CTD PMID:20713136 NCBI chr 1:14,401,103...14,416,369
Ensembl chr 1:14,402,913...14,412,807
JBrowse link
G Tnfaip6 TNF alpha induced protein 6 increases expression ISO Eugenol results in increased expression of TNFAIP6 mRNA CTD PMID:17374397, PMID:20713136 NCBI chr 3:37,545,238...37,564,704
Ensembl chr 3:37,545,238...37,564,699
JBrowse link
G Tp53 tumor protein p53 multiple interactions
increases mutagenesis
increases expression
EXP
ISO
Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of TP53 protein]
Eugenol results in increased mutagenesis of TP53 gene
Eugenol results in increased expression of TRP53 mRNA; Eugenol results in increased expression of TRP53 protein
Eugenol promotes the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of TRP53 protein]
CTD PMID:15576237, PMID:19851710, PMID:20043298, PMID:20537511 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Tp63 tumor protein p63 decreases expression ISO Eugenol results in decreased expression of TP63 mRNA CTD PMID:17936526 NCBI chr11:78,234,853...78,456,559
Ensembl chr11:78,234,800...78,456,501
JBrowse link
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 multiple interactions
increases activity
EXP [2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)-N-(4-isopropylphenyl)acetamide binds to and results in decreased activity of TRPA1 protein] which results in decreased susceptibility to Eugenol
Eugenol results in increased activity of TRPA1 protein
CTD PMID:22426238 NCBI chr 5:3,783,247...3,836,485
Ensembl chr 5:3,783,247...3,836,485
JBrowse link
G Trpv3 transient receptor potential cation channel, subfamily V, member 3 multiple interactions
increases activity
ISO
EXP
Eugenol binds to and results in increased activity of TRPV3 protein
[Eugenol binds to and results in increased activity of TRPV3 protein] which results in increased transport of Calcium; Eugenol binds to and results in increased activity of TRPV3 protein
[Eugenol results in increased activity of TRPV3 protein] which results in increased transport of Calcium
CTD PMID:16617338, PMID:20086034, PMID:21593771 NCBI chr10:59,829,755...59,863,780
Ensembl chr10:59,831,241...59,860,987
JBrowse link
G Txn2 thioredoxin 2 increases expression ISO Eugenol results in increased expression of TXN2 mRNA CTD PMID:20566472 NCBI chr 7:119,144,350...119,158,173
Ensembl chr 7:119,144,351...119,158,201
JBrowse link
G Txnrd1 thioredoxin reductase 1 increases expression ISO Eugenol results in increased expression of TXNRD1 mRNA CTD PMID:20566472, PMID:23445166 NCBI chr 7:26,946,124...26,984,400
Ensembl chr 7:26,946,125...26,984,400
JBrowse link
G Txnrd2 thioredoxin reductase 2 increases expression ISO Eugenol results in increased expression of TXNRD2 mRNA CTD PMID:20566472 NCBI chr11:86,667,994...86,716,063
Ensembl chr11:86,667,997...86,716,254
JBrowse link
G Ugdh UDP-glucose 6-dehydrogenase increases expression ISO Eugenol results in increased expression of UGDH mRNA CTD PMID:16292757 NCBI chr14:44,479,614...44,502,845
Ensembl chr14:44,479,614...44,502,845
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases glucuronidation ISO UGT1A1 protein results in increased glucuronidation of Eugenol CTD PMID:14557274 NCBI chr 9:95,295,701...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 increases expression ISO Eugenol results in increased expression of UGT1A6 mRNA CTD PMID:20566472 NCBI chr 9:95,241,609...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt1a8 UDP glucuronosyltransferase family 1 member A8 increases glucuronidation ISO UGT1A8 protein results in increased glucuronidation of Eugenol CTD PMID:14557274 NCBI chr 9:95,221,474...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 increases glucuronidation ISO UGT1A9 protein results in increased glucuronidation of Eugenol CTD PMID:14557274 NCBI chr 9:95,161,157...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt2b15 UDP glucuronosyltransferase family 2 member B15 increases metabolic processing EXP UGT2B15 protein results in increased metabolism of Eugenol CTD PMID:7574722 NCBI chr14:22,375,428...22,486,291
Ensembl chr14:22,375,955...22,534,720
JBrowse link
G Ugt2b17 UDP glucuronosyltransferase family 2 member B17 increases metabolic processing ISO UGT2B17 protein results in increased metabolism of Eugenol CTD PMID:8798464 NCBI chr14:22,724,399...22,736,148
Ensembl chr14:22,724,070...22,825,444
JBrowse link
G Vdr vitamin D receptor increases expression ISO Eugenol results in increased expression of VDR mRNA CTD PMID:17374397 NCBI chr 7:139,344,452...139,394,138
Ensembl chr 7:139,342,063...139,394,166
JBrowse link
G Zbtb17 zinc finger and BTB domain containing 17 decreases expression ISO Eugenol results in decreased expression of ZBTB17 mRNA CTD PMID:17374397 NCBI chr 5:159,993,799...160,014,899
Ensembl chr 5:159,993,799...160,014,895
JBrowse link
guaiacol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alb albumin affects binding ISO Guaiacol binds to ALB protein CTD PMID:11334365 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Car1 carbonic anhydrase 1 decreases activity ISO Guaiacol results in decreased activity of CA1 protein CTD PMID:19231207 NCBI chr 2:88,185,204...88,227,486
Ensembl chr 2:88,217,188...88,227,479
JBrowse link
G Car2 carbonic anhydrase 2 decreases activity ISO Guaiacol results in decreased activity of CA2 protein CTD PMID:19231207 NCBI chr 2:88,097,740...88,112,868
Ensembl chr 2:88,097,720...88,113,029
JBrowse link
G Comt catechol-O-methyltransferase multiple interactions ISO COMT mutant form inhibits the reaction [catechol results in increased abundance of Guaiacol] CTD PMID:24141029 NCBI chr11:86,715,981...86,735,630
Ensembl chr11:86,715,981...86,735,622
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO Guaiacol inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA] CTD PMID:17465205 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Sult1c3 sulfotransferase family 1C member 3 increases sulfation ISO SULT1C1 protein results in increased sulfation of Guaiacol CTD PMID:9560327 NCBI chr 9:4,931,038...4,978,847
Ensembl chr 9:4,930,818...4,978,892
JBrowse link
isoeugenol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor increases activity
affects localization
multiple interactions
ISO isoeugenol results in increased activity of AHR protein
isoeugenol affects the localization of AHR protein
3'-methoxy-4'-nitroflavone inhibits the reaction [isoeugenol results in increased activity of AHR protein]
CTD PMID:16972787, PMID:22686307 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Ahrr aryl-hydrocarbon receptor repressor increases expression ISO isoeugenol results in increased expression of AHRR mRNA CTD PMID:22686307 NCBI chr 1:31,603,297...31,698,329
Ensembl chr 1:31,603,297...31,698,329
JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B increases expression ISO isoeugenol results in increased expression of AKR1B1 mRNA CTD PMID:20566472 NCBI chr 4:61,706,866...61,720,959
Ensembl chr 4:61,706,864...61,720,956
JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 increases expression ISO isoeugenol results in increased expression of AKR1B10 mRNA CTD PMID:20566472 NCBI chr 4:61,813,265...61,830,371
Ensembl chr 4:61,771,970...61,828,657
JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 increases expression
increases activity
ISO isoeugenol results in increased expression of AKR1C2 mRNA
isoeugenol results in increased activity of AKR1C2 promoter
CTD PMID:20491607, PMID:21195160 NCBI chr17:69,388,337...69,435,160
Ensembl chr17:69,388,335...69,404,341
JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 increases expression ISO isoeugenol results in increased expression of AKR1C3 mRNA CTD PMID:20566472 NCBI chr17:69,761,126...69,778,021
Ensembl chr17:69,761,118...69,778,021
JBrowse link
G Ar androgen receptor affects binding EXP isoeugenol binds to AR protein CTD PMID:14565775 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO isoeugenol results in increased expression of ATF3 mRNA CTD PMID:23999411 NCBI chr13:109,817,892...109,849,632
Ensembl chr13:109,817,728...109,849,632
JBrowse link
G Cat catalase increases expression ISO isoeugenol results in increased expression of CAT mRNA CTD PMID:20566472 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases secretion ISO isoeugenol results in decreased secretion of CCL2 protein CTD PMID:20488241 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl27 C-C motif chemokine ligand 27 increases expression ISO isoeugenol results in increased expression of CCL27 mRNA CTD PMID:17936526 NCBI chr 5:58,159,066...58,166,182
Ensembl chr 5:58,159,066...58,163,584
JBrowse link
G Cd274 CD274 molecule increases expression ISO isoeugenol results in increased expression of CD274 protein CTD PMID:20488241 NCBI chr 1:247,519,890...247,539,659
Ensembl chr 1:247,519,939...247,537,943
JBrowse link
G Cdk6 cyclin-dependent kinase 6 decreases expression ISO isoeugenol results in decreased expression of CDK6 protein CTD PMID:22686307 NCBI chr 4:27,781,728...27,969,653
Ensembl chr 4:27,785,647...27,966,398
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases expression ISO isoeugenol results in increased expression of CDKN1B protein CTD PMID:22686307 NCBI chr 4:168,689,043...168,694,159
Ensembl chr 4:168,689,163...168,693,964
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 increases expression ISO isoeugenol results in increased expression of CXCL2 protein CTD PMID:23178550 NCBI chr14:18,731,346...18,733,391
Ensembl chr14:18,731,378...18,733,391
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression ISO isoeugenol results in increased expression of CYP1A1 mRNA CTD PMID:20491607, PMID:22686307 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Dnajb4 DnaJ heat shock protein family (Hsp40) member B4 increases expression ISO isoeugenol results in increased expression of DNAJB4 mRNA CTD PMID:23999411, PMID:27965148 NCBI chr 2:257,394,692...257,425,344
Ensembl chr 2:257,394,818...257,425,242
JBrowse link
G Fech ferrochelatase increases expression ISO isoeugenol results in increased expression of FECH mRNA CTD PMID:20566472 NCBI chr18:59,941,992...59,975,192
Ensembl chr18:59,941,992...59,975,192
JBrowse link
G Ftl1 ferritin light chain 1 increases expression ISO isoeugenol results in increased expression of FTL mRNA CTD PMID:20566472 NCBI chr 1:101,448,190...101,450,034
Ensembl chr 1:101,448,346...101,449,829
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase increases expression ISO isoeugenol results in increased expression of G6PD mRNA CTD PMID:20566472 NCBI chr  X:156,274,800...156,293,935
Ensembl chr  X:156,274,800...156,293,926
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression ISO isoeugenol results in increased expression of GCLC mRNA CTD PMID:20566472 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO isoeugenol results in increased expression of GCLM mRNA CTD PMID:20566472, PMID:23999411, PMID:27965148 NCBI chr 2:225,827,504...225,847,876
Ensembl chr 2:225,827,504...225,847,874
JBrowse link
G Gpx3 glutathione peroxidase 3 increases expression ISO isoeugenol results in increased expression of GPX3 mRNA CTD PMID:20566472 NCBI chr10:40,247,436...40,255,423
Ensembl chr10:40,247,436...40,255,422
JBrowse link
G Gsr glutathione-disulfide reductase increases expression ISO isoeugenol results in increased expression of GSR mRNA CTD PMID:20566472 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO isoeugenol results in increased expression of HMOX1 mRNA CTD PMID:20491607, PMID:20566472, PMID:23445166 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hsph1 heat shock protein family H (Hsp110) member 1 increases expression ISO isoeugenol results in increased expression of HSPH1 mRNA CTD PMID:23999411 NCBI chr12:6,322,685...6,341,898
Ensembl chr12:6,322,668...6,341,902
JBrowse link
G Ifng interferon gamma increases secretion ISO isoeugenol results in increased secretion of IFNG protein CTD PMID:22245253 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Il18 interleukin 18 increases expression ISO isoeugenol results in increased expression of IL18 protein CTD PMID:23063874 NCBI chr 8:55,009,666...55,016,286
Ensembl chr 8:54,993,859...55,016,299
JBrowse link
G Il1a interleukin 1 alpha increases expression ISO isoeugenol results in increased expression of IL1A protein CTD PMID:23178550 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il2 interleukin 2 multiple interactions
increases secretion
ISO isoeugenol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA]; isoeugenol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased secretion of IL2 protein]
isoeugenol results in increased secretion of IL2 protein
CTD PMID:17630204, PMID:22245253 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854
JBrowse link
G Il6 interleukin 6 increases secretion ISO isoeugenol results in increased secretion of IL6 protein CTD PMID:22245253 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G LOC100912605 olfactory receptor 5D14-like multiple interactions ISO isoeugenol binds to and results in decreased activity of OLFR73 protein; isoeugenol binds to and results in increased activity of OLFR73 protein CTD PMID:15574817, PMID:21142015 NCBI chr 3:76,255,179...76,256,129
Ensembl chr 3:76,255,179...76,256,129
JBrowse link
G Maff MAF bZIP transcription factor F increases expression ISO isoeugenol results in increased expression of MAFF mRNA CTD PMID:20491607, PMID:20566472 NCBI chr 7:120,580,743...120,592,095
Ensembl chr 7:120,580,743...120,592,095
JBrowse link
G Mafg MAF bZIP transcription factor G increases expression ISO isoeugenol results in increased expression of MAFG mRNA CTD PMID:20566472 NCBI chr10:109,802,877...109,811,476
Ensembl chr10:109,806,159...109,811,323
JBrowse link
G Mafk MAF bZIP transcription factor K increases expression ISO isoeugenol results in increased expression of MAFK mRNA CTD PMID:20566472 NCBI chr12:16,923,989...16,934,706
Ensembl chr12:16,923,990...16,934,706
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO isoeugenol inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; MAPK1 protein affects the reaction [isoeugenol affects the expression of NOS2] CTD PMID:17698059 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO isoeugenol inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK3 protein]; MAPK3 protein affects the reaction [isoeugenol affects the expression of NOS2] CTD PMID:17698059 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Me1 malic enzyme 1 increases expression ISO isoeugenol results in increased expression of ME1 mRNA CTD PMID:20566472 NCBI chr 8:94,256,830...94,368,834
Ensembl chr 8:94,256,839...94,368,834
JBrowse link
G Mgst1 microsomal glutathione S-transferase 1 increases expression ISO isoeugenol results in increased expression of MGST1 mRNA CTD PMID:20566472 NCBI chr 4:172,119,382...172,134,609
Ensembl chr 4:172,119,331...172,134,607
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO isoeugenol inhibits the reaction [TNF protein results in increased activity of [NFKB1 protein binds to RELA protein]] CTD PMID:10871845 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO isoeugenol inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIA protein]; NFKBIA protein affects the reaction [isoeugenol affects the expression of NOS2] CTD PMID:17698059 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO isoeugenol inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; isoeugenol inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]; MAPK1 protein affects the reaction [isoeugenol affects the expression of NOS2]; MAPK3 protein affects the reaction [isoeugenol affects the expression of NOS2]; NFKBIA protein affects the reaction [isoeugenol affects the expression of NOS2] CTD PMID:17698059 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO isoeugenol results in increased expression of NQO1 mRNA CTD PMID:20491607, PMID:20566472 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Pgd phosphogluconate dehydrogenase increases expression ISO isoeugenol results in increased expression of PGD mRNA CTD PMID:20566472 NCBI chr 5:165,966,128...165,982,327 JBrowse link
G Ptgr1 prostaglandin reductase 1 increases expression ISO isoeugenol results in increased expression of PTGR1 mRNA CTD PMID:20566472 NCBI chr 5:76,110,746...76,129,361
Ensembl chr 5:76,110,738...76,129,441
JBrowse link
G Rb1 RB transcriptional corepressor 1 decreases expression ISO isoeugenol results in decreased expression of RB1 protein CTD PMID:22686307 NCBI chr15:55,081,582...55,209,060
Ensembl chr15:55,083,140...55,209,342
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO isoeugenol inhibits the reaction [TNF protein results in increased activity of [NFKB1 protein binds to RELA protein]]
isoeugenol inhibits the reaction [Lipopolysaccharides affects the localization of RELA protein]
CTD PMID:10871845, PMID:17698059 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Socs3 suppressor of cytokine signaling 3 increases expression
multiple interactions
ISO isoeugenol results in increased expression of SOCS3 mRNA; isoeugenol results in increased expression of SOCS3 protein
KT 5720 inhibits the reaction [isoeugenol results in increased expression of SOCS3 mRNA]
CTD PMID:21969073 NCBI chr10:106,973,863...106,976,969
Ensembl chr10:106,975,178...106,976,040
JBrowse link
G Sod1 superoxide dismutase 1 increases expression ISO isoeugenol results in increased expression of SOD1 mRNA CTD PMID:20566472 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Sod2 superoxide dismutase 2 increases expression ISO isoeugenol results in increased expression of SOD2 mRNA CTD PMID:20566472 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Sod3 superoxide dismutase 3 increases expression ISO isoeugenol results in increased expression of SOD3 mRNA CTD PMID:20566472 NCBI chr14:60,958,583...60,971,143
Ensembl chr14:60,958,592...60,964,324
JBrowse link
G Srxn1 sulfiredoxin 1 increases expression ISO isoeugenol results in increased expression of SRXN1 mRNA CTD PMID:20566472 NCBI chr 3:147,608,850...147,614,410
Ensembl chr 3:147,609,095...147,632,801
JBrowse link
G Tlr2 toll-like receptor 2 increases expression ISO isoeugenol results in increased expression of TLR2 mRNA CTD PMID:17936526 NCBI chr 2:182,840,171...182,846,061
Ensembl chr 2:182,840,727...182,846,061
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases secretion
ISO isoeugenol inhibits the reaction [TNF protein results in increased activity of [NFKB1 protein binds to RELA protein]]
isoeugenol results in increased secretion of TNF protein
CTD PMID:10871845, PMID:22245253 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Trim16 tripartite motif-containing 16 multiple interactions
increases expression
ISO [Indomethacin co-treated with isoeugenol] results in increased expression of TRIM16 mRNA
isoeugenol results in increased expression of TRIM16 mRNA
CTD PMID:21284934 NCBI chr10:49,231,660...49,254,653
Ensembl chr10:49,231,730...49,254,621
JBrowse link
G Txn2 thioredoxin 2 increases expression ISO isoeugenol results in increased expression of TXN2 mRNA CTD PMID:20566472 NCBI chr 7:119,144,350...119,158,173
Ensembl chr 7:119,144,351...119,158,201
JBrowse link
G Txnrd1 thioredoxin reductase 1 increases expression ISO isoeugenol results in increased expression of TXNRD1 mRNA CTD PMID:20566472, PMID:23445166 NCBI chr 7:26,946,124...26,984,400
Ensembl chr 7:26,946,125...26,984,400
JBrowse link
G Txnrd2 thioredoxin reductase 2 increases expression ISO isoeugenol results in increased expression of TXNRD2 mRNA CTD PMID:20566472 NCBI chr11:86,667,994...86,716,063
Ensembl chr11:86,667,997...86,716,254
JBrowse link
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 increases expression ISO isoeugenol results in increased expression of UGT1A6 mRNA CTD PMID:20566472 NCBI chr 9:95,241,609...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Zfp36 zinc finger protein 36 increases expression
multiple interactions
ISO isoeugenol results in increased expression of ZFP36 protein
KT 5720 inhibits the reaction [isoeugenol results in increased expression of ZFP36 protein]; SB 203580 inhibits the reaction [isoeugenol results in increased expression of ZFP36 protein]
CTD PMID:21969073 NCBI chr 1:85,380,088...85,382,565
Ensembl chr 1:85,380,088...85,382,569
JBrowse link
naringin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaca acetyl-CoA carboxylase alpha multiple interactions ISO [naringin co-treated with Dietary Fats] results in decreased expression of ACACA mRNA CTD PMID:22198281 NCBI chr10:71,519,392...71,719,910
Ensembl chr10:71,536,533...71,719,910
JBrowse link
G Ache acetylcholinesterase multiple interactions EXP [NG-Nitroarginine Methyl Ester co-treated with bisphenol A co-treated with naringin] results in increased expression of ACHE protein; [NG-Nitroarginine Methyl Ester co-treated with naringin] results in increased expression of ACHE protein; naringin inhibits the reaction [[NG-Nitroarginine Methyl Ester co-treated with bisphenol A] results in increased expression of ACHE protein]; naringin inhibits the reaction [NG-Nitroarginine Methyl Ester results in increased expression of ACHE protein] CTD PMID:32428650 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
JBrowse link
G Acox1 acyl-CoA oxidase 1 multiple interactions ISO naringin inhibits the reaction [Dietary Fats results in decreased expression of ACOX1 mRNA] CTD PMID:22198281 NCBI chr10:104,724,534...104,748,003
Ensembl chr10:104,722,958...104,748,050
JBrowse link
G Acp5 acid phosphatase 5, tartrate resistant multiple interactions
decreases expression
ISO naringin inhibits the reaction [[TNFSF11 protein co-treated with CSF1R protein] results in increased expression of ACP5 mRNA]; naringin inhibits the reaction [Polymethyl Methacrylate analog results in increased expression of and results in increased activity of ACP5 protein]
naringin results in decreased expression of ACP5 mRNA
CTD PMID:21835177, PMID:24376342 NCBI chr 8:23,142,733...23,149,067
Ensembl chr 8:23,142,734...23,148,396
JBrowse link
G Ada adenosine deaminase multiple interactions EXP naringin inhibits the reaction [[NG-Nitroarginine Methyl Ester co-treated with bisphenol A] results in increased activity of ADA protein]; naringin inhibits the reaction [bisphenol A results in increased activity of ADA protein]; naringin inhibits the reaction [NG-Nitroarginine Methyl Ester results in increased activity of ADA protein] CTD PMID:32428650 NCBI chr 3:160,115,840...160,139,947
Ensembl chr 3:160,115,842...160,139,947
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing multiple interactions ISO naringin inhibits the reaction [Dietary Fats results in decreased expression of ADIPOQ protein] CTD PMID:22198281 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488
JBrowse link
G Agt angiotensinogen multiple interactions ISO naringin inhibits the reaction [AGT protein results in increased expression of CYP11B2 mRNA]; naringin inhibits the reaction [AGT protein results in increased secretion of Aldosterone] CTD PMID:22798349 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions
increases phosphorylation
EXP
ISO
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [naringin results in increased phosphorylation of AKT1 protein]; naringin inhibits the reaction [Methylprednisolone results in decreased phosphorylation of AKT1 protein]; naringin inhibits the reaction [TNF protein results in increased phosphorylation of AKT1 protein]; plerixafor octahydrochloride inhibits the reaction [naringin results in increased phosphorylation of AKT1 protein]
naringin inhibits the reaction [Dexamethasone results in decreased phosphorylation of AKT1 protein]; naringin inhibits the reaction [Dexamethasone results in increased expression of AKT1 mRNA]
CTD PMID:19810018, PMID:25773745, PMID:29510123, PMID:30878453 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Angpt1 angiopoietin 1 affects expression EXP naringin affects the expression of ANGPT1 mRNA CTD PMID:24880026 NCBI chr 7:81,338,327...81,592,459
Ensembl chr 7:81,342,280...81,592,206
JBrowse link
G Aqp1 aquaporin 1 multiple interactions ISO naringin inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in decreased expression of AQP1 mRNA]; naringin inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in decreased expression of AQP1 protein] CTD PMID:31301536 NCBI chr 4:85,551,503...85,563,683
Ensembl chr 4:85,551,502...85,569,360
JBrowse link
G Aqp5 aquaporin 5 multiple interactions ISO naringin inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in decreased expression of AQP5 mRNA]; naringin inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in decreased expression of AQP5 protein] CTD PMID:31301536 NCBI chr 7:141,249,044...141,252,576
Ensembl chr 7:141,249,044...141,252,578
JBrowse link
G Atp6v0d2 ATPase H+ transporting V0 subunit D2 multiple interactions ISO naringin inhibits the reaction [[TNFSF11 protein co-treated with CSF1R protein] results in increased expression of ATP6V0D2 mRNA] CTD PMID:21835177 NCBI chr 5:33,843,591...33,892,446
Ensembl chr 5:33,843,519...33,892,462
JBrowse link
G Bad BCL2-associated agonist of cell death multiple interactions EXP
ISO
naringin inhibits the reaction [3-nitropropionic acid results in increased expression of BAD mRNA]
naringin inhibits the reaction [Dexamethasone results in increased phosphorylation of BAD protein]
CTD PMID:21945202, PMID:30878453 NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
multiple interactions
ISO
EXP
naringin results in increased expression of BAX mRNA
naringin inhibits the reaction [Dexamethasone results in increased expression of BAX protein]
naringin inhibits the reaction [Cadmium Chloride results in increased expression of BAX protein]
[naringin co-treated with Pioglitazone] inhibits the reaction [Quinolinic Acid results in increased expression of BAX mRNA]; naringin inhibits the reaction [3-nitropropionic acid results in increased expression of BAX mRNA]; naringin inhibits the reaction [Quinolinic Acid results in increased expression of BAX mRNA]
CTD PMID:21945202, PMID:22847135, PMID:28422390, PMID:30130594, PMID:30878453 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions EXP
ISO
[naringin co-treated with Pioglitazone] inhibits the reaction [Quinolinic Acid results in decreased expression of BCL2 mRNA]; naringin inhibits the reaction [3-nitropropionic acid results in decreased expression of BCL2 mRNA]; naringin inhibits the reaction [Quinolinic Acid results in decreased expression of BCL2 mRNA]
naringin inhibits the reaction [Dexamethasone results in decreased expression of BCL2 protein]
naringin inhibits the reaction [Cadmium Chloride results in decreased expression of BCL2 protein]
CTD PMID:21945202, PMID:28422390, PMID:30130594, PMID:30878453 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bglap bone gamma-carboxyglutamate protein increases expression
increases secretion
multiple interactions
ISO
EXP
naringin results in increased expression of BGLAP mRNA; naringin results in increased expression of BGLAP protein
naringin results in increased secretion of BGLAP protein
fulvestrant inhibits the reaction [naringin results in increased secretion of BGLAP protein]
CTD PMID:18495116, PMID:21741227, PMID:23596885 NCBI chr 2:187,741,770...187,748,445
Ensembl chr 2:187,741,770...187,742,747
JBrowse link
G Bmp2 bone morphogenetic protein 2 multiple interactions
decreases expression
increases secretion
increases expression
ISO
EXP
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [naringin promotes the reaction [FOS protein binds to BMP2 promoter]]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [naringin promotes the reaction [JUN protein binds to BMP2 promoter]]; FOS protein affects the reaction [naringin results in increased expression of BMP2 mRNA]; FOS protein affects the reaction [naringin results in increased expression of BMP2 protein]; JUN protein affects the reaction [naringin results in increased expression of BMP2 mRNA]; JUN protein affects the reaction [naringin results in increased expression of BMP2 protein]; naringin promotes the reaction [FOS protein binds to BMP2 promoter]; naringin promotes the reaction [JUN protein binds to BMP2 promoter]
naringin results in decreased expression of BMP2 mRNA
fulvestrant inhibits the reaction [naringin results in increased secretion of BMP2 protein]
naringin results in increased expression of BMP2 mRNA; naringin results in increased expression of BMP2 protein
CTD PMID:18495116, PMID:21820093, PMID:23596885 NCBI chr 3:126,335,963...126,346,771
Ensembl chr 3:126,335,863...126,346,318
JBrowse link
G Bmp3 bone morphogenetic protein 3 decreases expression ISO naringin results in decreased expression of BMP3 mRNA CTD PMID:18495116 NCBI chr14:12,362,912...12,387,572
Ensembl chr14:12,359,363...12,387,102
JBrowse link
G Bmp4 bone morphogenetic protein 4 increases expression ISO naringin results in increased expression of BMP4 mRNA CTD PMID:24915843 NCBI chr15:20,776,060...20,791,013
Ensembl chr15:20,776,054...20,822,740
JBrowse link
G Calcr calcitonin receptor multiple interactions ISO naringin inhibits the reaction [[TNFSF11 protein co-treated with CSF1R protein] results in increased expression of CALCR mRNA] CTD PMID:21835177 NCBI chr 4:28,627,439...28,702,559
Ensembl chr 4:28,627,442...28,702,559
JBrowse link
G Casp3 caspase 3 increases expression
multiple interactions
ISO
EXP
naringin results in increased expression of CASP3 mRNA
naringin inhibits the reaction [Dexamethasone results in increased cleavage of CASP3 protein]
naringin inhibits the reaction [Cadmium Chloride results in increased cleavage of CASP3 protein]
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [naringin inhibits the reaction [[Oxygen deficiency co-treated with Oxygen] results in increased cleavage of and results in increased activity of CASP3 protein]]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [naringin inhibits the reaction [[Oxygen deficiency co-treated with Oxygen] results in increased cleavage of and results in increased activity of CASP3 protein]]; [naringin co-treated with Pioglitazone] inhibits the reaction [Quinolinic Acid results in increased expression of CASP3 mRNA]; naringin inhibits the reaction [3-nitropropionic acid results in increased cleavage of CASP3 protein]; naringin inhibits the reaction [[Oxygen deficiency co-treated with Oxygen] results in increased cleavage of and results in increased activity of CASP3 protein]; naringin inhibits the reaction [Cisplatin results in increased expression of CASP3 mRNA]; naringin inhibits the reaction [Quinolinic Acid results in increased expression of CASP3 mRNA]; rottlerin inhibits the reaction [naringin inhibits the reaction [[Oxygen deficiency co-treated with Oxygen] results in increased cleavage of and results in increased activity of CASP3 protein]]
CTD PMID:21945202, PMID:22847135, PMID:25773745, PMID:26612654, PMID:28422390, PMID:30130594, PMID:30878453 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp9 caspase 9 increases expression
multiple interactions
ISO
EXP
naringin results in increased expression of CASP9 mRNA
[bisphenol A co-treated with naringin] results in decreased expression of CASP9 protein; [NG-Nitroarginine Methyl Ester co-treated with bisphenol A co-treated with naringin] results in decreased expression of CASP9 protein; naringin inhibits the reaction [[NG-Nitroarginine Methyl Ester co-treated with bisphenol A] results in increased expression of CASP9 protein]; naringin inhibits the reaction [[Oxygen deficiency co-treated with Oxygen] results in increased cleavage of and results in increased activity of CASP9 protein]; naringin inhibits the reaction [bisphenol A results in increased expression of CASP9 protein]; naringin inhibits the reaction [NG-Nitroarginine Methyl Ester results in increased expression of CASP9 protein]
CTD PMID:22847135, PMID:25773745, PMID:32428650 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cat catalase multiple interactions ISO
EXP
naringin inhibits the reaction [Dietary Fats results in decreased activity of CAT protein]; naringin inhibits the reaction [Ferric Compounds results in decreased activity of CAT protein]
naringin inhibits the reaction [3-nitropropionic acid results in decreased activity of CAT protein]; naringin inhibits the reaction [[Oxygen deficiency co-treated with Oxygen] results in decreased activity of CAT protein]; naringin inhibits the reaction [Cisplatin results in decreased activity of CAT protein]; naringin inhibits the reaction [Cisplatin results in increased expression of CAT protein]; naringin inhibits the reaction [nickel sulfate results in decreased activity of CAT protein]
CTD PMID:20950607, PMID:21345335, PMID:21945202, PMID:22198281, PMID:25773745, PMID:26120027, PMID:26612654 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO naringin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of CCL2 mRNA]; naringin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of CCL2 protein] CTD PMID:22965302 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 multiple interactions ISO naringin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of CCL3 mRNA]; naringin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of CCL3 protein] CTD PMID:22965302 NCBI chr10:70,869,516...70,871,066
Ensembl chr10:70,869,513...70,871,066
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 multiple interactions ISO naringin inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased expression of CCL5 protein] CTD PMID:21500970 NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315
JBrowse link
G Ccnd1 cyclin D1 decreases expression
multiple interactions
increases expression
ISO
EXP
naringin results in decreased expression of CCND1 protein
naringin inhibits the reaction [Dexamethasone results in increased expression of CCND1 mRNA]
naringin inhibits the reaction [Hydrogen Peroxide results in decreased expression of CCND1 protein]
naringin results in increased expression of CCND1 mRNA
CTD PMID:18296682, PMID:18951945, PMID:24915843, PMID:26482937, PMID:30878453 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Ccne1 cyclin E1 decreases expression ISO
EXP
naringin results in decreased expression of CCNE1 protein CTD PMID:18296682, PMID:18951945 NCBI chr 1:94,485,830...94,495,112
Ensembl chr 1:94,485,832...94,494,980
JBrowse link
G Cdk2 cyclin dependent kinase 2 multiple interactions EXP
ISO
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [naringin results in decreased expression of CDK2 protein]; HRAS protein affects the reaction [naringin results in decreased expression of CDK2 protein]; naringin promotes the reaction [CDKN1A protein binds to CDK2 protein]; naringin results in decreased expression of and results in decreased activity of CDK2 protein; RAF1 protein affects the reaction [naringin results in decreased expression of CDK2 protein]
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [naringin results in increased expression of CDK2 protein]; HRAS protein affects the reaction [naringin results in decreased expression of CDK2 protein]; naringin results in decreased expression of and results in decreased activity of CDK2 protein
CTD PMID:18296682, PMID:18951945 NCBI chr 7:3,124,953...3,132,533
Ensembl chr 7:3,124,954...3,132,457
JBrowse link
G Cdk4 cyclin-dependent kinase 4 multiple interactions ISO
EXP
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [naringin results in increased expression of CDK4 protein]; HRAS protein affects the reaction [naringin results in decreased expression of CDK4 protein]; naringin promotes the reaction [CDKN1A protein binds to CDK4 protein]; naringin results in decreased expression of and results in decreased activity of CDK4 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [naringin results in decreased expression of CDK4 protein]; HRAS protein affects the reaction [naringin results in decreased expression of CDK4 protein]; naringin promotes the reaction [CDKN1A protein binds to CDK4 protein]; naringin results in decreased expression of and results in decreased activity of CDK4 protein; RAF1 protein affects the reaction [naringin results in decreased expression of CDK4 protein]
CTD PMID:18296682, PMID:18951945 NCBI chr 7:70,345,971...70,352,689
Ensembl chr 7:70,349,863...70,352,418
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
increases expression
ISO
EXP
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [naringin results in increased expression of CDKN1A protein]; HRAS protein affects the reaction [naringin results in increased expression of CDKN1A protein]; naringin promotes the reaction [CDKN1A protein binds to CDK4 protein]; RAF1 protein affects the reaction [naringin results in increased expression of CDKN1A protein]
naringin results in increased expression of CDKN1A mRNA; naringin results in increased expression of CDKN1A protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [naringin results in increased expression of CDKN1A protein]; HRAS protein affects the reaction [naringin results in increased expression of CDKN1A protein]; naringin promotes the reaction [CDKN1A protein binds to CDK2 protein]; naringin promotes the reaction [CDKN1A protein binds to CDK4 protein]; RAF1 protein affects the reaction [naringin results in increased expression of CDKN1A protein]
CTD PMID:18296682, PMID:18951945 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cftr CF transmembrane conductance regulator multiple interactions ISO naringin inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in decreased expression of CFTR mRNA]; naringin inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in decreased expression of CFTR protein] CTD PMID:31301536 NCBI chr 4:42,693,263...42,860,679
Ensembl chr 4:42,692,836...42,860,676
JBrowse link
G Col1a1 collagen type I alpha 1 chain increases expression ISO naringin results in increased expression of COL1A1 mRNA CTD PMID:21741227 NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A multiple interactions ISO [Dietary Fats co-treated with naringin] results in decreased expression of CPT1A mRNA CTD PMID:22198281 NCBI chr 1:218,568,157...218,629,679
Ensembl chr 1:218,569,510...218,629,678
JBrowse link
G Csf1r colony stimulating factor 1 receptor multiple interactions ISO naringin inhibits the reaction [[TNFSF11 protein co-treated with CSF1R protein] results in increased expression of ACP5 mRNA]; naringin inhibits the reaction [[TNFSF11 protein co-treated with CSF1R protein] results in increased expression of ATP6V0D2 mRNA]; naringin inhibits the reaction [[TNFSF11 protein co-treated with CSF1R protein] results in increased expression of CALCR mRNA]; naringin inhibits the reaction [[TNFSF11 protein co-treated with CSF1R protein] results in increased expression of CTSK mRNA] CTD PMID:21835177 NCBI chr18:56,414,493...56,458,300
Ensembl chr18:56,414,488...56,458,300
JBrowse link
G Ctnnb1 catenin beta 1 increases expression
multiple interactions
ISO naringin results in increased expression of CTNNB1 mRNA
naringin inhibits the reaction [Hydrogen Peroxide results in decreased expression of CTNNB1 protein]
CTD PMID:24915843, PMID:26482937 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
JBrowse link
G Ctsb cathepsin B multiple interactions EXP naringin inhibits the reaction [Isoproterenol results in decreased activity of CTSB protein]; naringin inhibits the reaction [Isoproterenol results in increased activity of CTSB protein] CTD PMID:17188415 NCBI chr15:46,316,741...46,337,613
Ensembl chr15:46,316,741...46,337,612
JBrowse link
G Ctsd cathepsin D multiple interactions EXP naringin inhibits the reaction [Isoproterenol results in increased activity of CTSD protein] CTD PMID:17188415 NCBI chr 1:215,541,570...215,553,446
Ensembl chr 1:215,541,542...215,553,451
JBrowse link
G Ctsk cathepsin K multiple interactions
decreases expression
ISO naringin inhibits the reaction [[TNFSF11 protein co-treated with CSF1R protein] results in increased expression of CTSK mRNA]
naringin results in decreased expression of CTSK mRNA
CTD PMID:21835177, PMID:24376342 NCBI chr 2:196,655,469...196,666,447
Ensembl chr 2:196,655,469...196,666,446
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 increases expression EXP naringin results in increased expression of CXCL12 protein CTD PMID:29510123 NCBI chr 4:149,261,044...149,273,891
Ensembl chr 4:149,261,044...149,273,891
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 affects expression
multiple interactions
ISO naringin affects the expression of CXCL2 mRNA
naringin inhibits the reaction [OVAL protein results in increased expression of CXCL2 protein]
CTD PMID:24131540, PMID:25117567 NCBI chr14:18,731,346...18,733,391
Ensembl chr14:18,731,378...18,733,391
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 increases expression EXP naringin results in increased expression of CXCR4 protein CTD PMID:29510123 NCBI chr13:45,314,952...45,318,856
Ensembl chr13:45,314,933...45,318,878
JBrowse link
G Cyba cytochrome b-245 alpha chain multiple interactions ISO naringin inhibits the reaction [TNF protein results in increased expression of CYBA mRNA]; naringin inhibits the reaction [TNF protein results in increased expression of CYBA protein] CTD PMID:25391245 NCBI chr19:55,249,634...55,257,824
Ensembl chr19:55,249,616...55,257,876
JBrowse link
G Cycs cytochrome c, somatic multiple interactions ISO naringin inhibits the reaction [Cadmium Chloride results in increased expression of CYCS protein] CTD PMID:28422390 NCBI chr 4:80,331,226...80,333,326
Ensembl chr 4:80,331,227...80,333,326
JBrowse link
G Cyp11b3 cytochrome P450, family 11, subfamily b, polypeptide 3 multiple interactions ISO naringin inhibits the reaction [AGT protein results in increased expression of CYP11B2 mRNA] CTD PMID:22798349 NCBI chr 7:116,155,928...116,161,781
Ensembl chr 7:116,156,219...116,255,167
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases activity ISO naringin results in decreased activity of CYP1A1 protein CTD PMID:21053930 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases activity ISO naringin results in decreased activity of CYP1A2 protein CTD PMID:21053930 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions ISO naringin binds to and results in decreased activity of CYP1B1 protein CTD PMID:21053930 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Dhfr dihydrofolate reductase decreases activity ISO naringin results in decreased activity of DHFR protein CTD PMID:25418905 NCBI chr 2:21,931,887...21,958,927
Ensembl chr 2:21,931,493...21,962,453
JBrowse link
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 multiple interactions ISO DKK1 protein inhibits the reaction [naringin inhibits the reaction [Hydrogen Peroxide results in decreased expression of RUNX2 mRNA]] CTD PMID:26482937 NCBI chr 1:248,952,896...248,956,579
Ensembl chr 1:248,895,738...248,898,607
JBrowse link
G Egf epidermal growth factor multiple interactions ISO naringin inhibits the reaction [EGF protein affects the localization of RELA protein]; naringin inhibits the reaction [EGF protein results in increased expression of and results in increased phosphorylation of EGFR protein]; naringin inhibits the reaction [EGF protein results in increased expression of MUC5AC mRNA]; naringin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK1 protein]; naringin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK3 protein]; naringin inhibits the reaction [EGF protein results in increased secretion of MUC5AC protein] CTD PMID:22766066 NCBI chr 2:68,820,616...68,895,537 JBrowse link
G Egfr epidermal growth factor receptor multiple interactions ISO naringin inhibits the reaction [EGF protein results in increased expression of and results in increased phosphorylation of EGFR protein] CTD PMID:22766066 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions
increases expression
EXP fulvestrant inhibits the reaction [naringin results in increased expression of ESR1 mRNA] CTD PMID:23596885 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Esr2 estrogen receptor 2 multiple interactions
increases expression
EXP fulvestrant inhibits the reaction [naringin results in increased expression of ESR2 mRNA] CTD PMID:23596885 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
JBrowse link
G Fabp4 fatty acid binding protein 4 multiple interactions ISO naringin inhibits the reaction [Dietary Fats results in increased expression of FABP4 mRNA] CTD PMID:22198281 NCBI chr 2:93,792,666...93,797,267
Ensembl chr 2:93,792,601...93,797,305
JBrowse link
G Fadd Fas associated via death domain increases expression ISO naringin results in increased expression of FADD mRNA CTD PMID:22847135 NCBI chr 1:217,746,176...217,748,581
Ensembl chr 1:217,742,929...217,748,628
JBrowse link
G Fas Fas cell surface death receptor increases expression ISO naringin results in increased expression of FAS mRNA CTD PMID:22847135 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Fasn fatty acid synthase multiple interactions ISO naringin affects the reaction [LEPR protein affects the activity of FASN protein]; naringin inhibits the reaction [Dietary Fats results in increased expression of FASN mRNA] CTD PMID:16427799, PMID:22198281 NCBI chr10:109,987,735...110,005,901
Ensembl chr10:109,987,735...110,005,901
JBrowse link
G Fgf2 fibroblast growth factor 2 multiple interactions
increases expression
EXP fulvestrant inhibits the reaction [naringin results in increased expression of FGF2 mRNA] CTD PMID:23596885 NCBI chr 2:124,081,072...124,134,133
Ensembl chr 2:124,081,072...124,134,681
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [naringin promotes the reaction [FOS protein binds to BMP2 promoter]]; FOS protein affects the reaction [naringin results in increased expression of BMP2 mRNA]; FOS protein affects the reaction [naringin results in increased expression of BMP2 protein]; naringin promotes the reaction [FOS protein binds to BMP2 promoter]
naringin results in increased expression of FOS mRNA
CTD PMID:18495116 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G G6pc glucose-6-phosphatase, catalytic subunit multiple interactions ISO naringin affects the reaction [LEPR protein affects the expression of G6PC mRNA]; naringin inhibits the reaction [Dietary Fats results in increased expression of G6PC mRNA] CTD PMID:16427799, PMID:22198281 NCBI chr10:89,286,009...89,296,213
Ensembl chr10:89,285,855...89,296,213
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase multiple interactions EXP
ISO
naringin inhibits the reaction [nickel sulfate results in decreased activity of G6PD protein]
naringin affects the reaction [LEPR protein affects the activity of G6PD protein]
CTD PMID:16427799, PMID:20950607 NCBI chr  X:156,274,800...156,293,935
Ensembl chr  X:156,274,800...156,293,926
JBrowse link
G Gal galanin and GMAP prepropeptide multiple interactions EXP naringin inhibits the reaction [Isoproterenol results in increased activity of GAL protein] CTD PMID:17188415 NCBI chr 1:218,653,059...218,657,922
Ensembl chr 1:218,652,917...218,657,925
JBrowse link
G Gck glucokinase multiple interactions ISO naringin affects the reaction [LEPR protein affects the expression of GCK mRNA] CTD PMID:16427799 NCBI chr14:86,149,146...86,191,589
Ensembl chr14:86,148,928...86,190,659
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions
increases expression
EXP 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [naringin results in increased expression of GCLC protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [naringin results in increased expression of GCLC protein]; [naringin co-treated with 3-nitropropionic acid] results in increased expression of GCLC mRNA; naringin promotes the reaction [[Oxygen deficiency co-treated with Oxygen] results in increased expression of GCLC protein]; rottlerin inhibits the reaction [naringin results in increased expression of GCLC protein]
naringin results in increased expression of GCLC mRNA; naringin results in increased expression of GCLC protein
CTD PMID:22871521, PMID:25773745 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions EXP naringin inhibits the reaction [sodium arsenite results in increased expression of GPT protein] CTD PMID:27174133 NCBI chr 7:117,759,083...117,761,932
Ensembl chr 7:117,759,083...117,761,931
JBrowse link
G Gpx1 glutathione peroxidase 1 increases activity ISO naringin results in increased activity of GPX1 protein CTD PMID:23603004 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions EXP
ISO
naringin inhibits the reaction [3-nitropropionic acid results in decreased activity of GSR protein]; naringin inhibits the reaction [nickel sulfate results in decreased activity of GSR protein]
naringin inhibits the reaction [Mercuric Chloride results in decreased activity of GSR protein]
CTD PMID:20950607, PMID:21945202, PMID:23650045 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Gstp1 glutathione S-transferase pi 1 increases expression
multiple interactions
EXP naringin results in increased expression of GSTP1 mRNA
[naringin co-treated with 3-nitropropionic acid] results in increased expression of GSTP1 mRNA
CTD PMID:22871521 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G Gusb glucuronidase, beta multiple interactions EXP naringin inhibits the reaction [Isoproterenol results in decreased activity of GUSB protein]; naringin inhibits the reaction [Isoproterenol results in increased activity of GUSB protein] CTD PMID:17188415 NCBI chr12:30,202,066...30,215,583
Ensembl chr12:30,198,822...30,227,771
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase multiple interactions EXP
ISO
naringin inhibits the reaction [Isoproterenol results in increased activity of HMGCR protein]
naringin affects the reaction [LEPR protein affects the activity of HMGCR protein]
CTD PMID:16427799, PMID:16906524 NCBI chr 2:27,480,224...27,500,654
Ensembl chr 2:27,480,226...27,500,654
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression
increases activity
ISO
EXP
naringin inhibits the reaction [Paraquat results in decreased expression of HMOX1 mRNA]; naringin inhibits the reaction [Paraquat results in decreased expression of HMOX1 protein]
naringin results in increased expression of HMOX1 mRNA; naringin results in increased expression of HMOX1 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [naringin results in increased expression of HMOX1 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [naringin results in increased expression of HMOX1 protein]; [naringin co-treated with 3-nitropropionic acid] results in increased expression of HMOX1 mRNA; naringin inhibits the reaction [sodium arsenite results in decreased expression of HMOX1 mRNA]; naringin promotes the reaction [[Oxygen deficiency co-treated with Oxygen] results in increased expression of HMOX1 protein]; rottlerin inhibits the reaction [naringin results in increased expression of HMOX1 protein]
naringin results in increased activity of HMOX1 protein
CTD PMID:22871521, PMID:23603004, PMID:25773745, PMID:27174133 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hras HRas proto-oncogene, GTPase multiple interactions
increases activity
ISO
EXP
HRAS protein affects the reaction [naringin results in decreased expression of CDK2 protein]; HRAS protein affects the reaction [naringin results in decreased expression of CDK4 protein]; HRAS protein affects the reaction [naringin results in increased expression of CDKN1A protein]; HRAS protein affects the reaction [naringin results in increased phosphorylation of MAPK1 protein]; HRAS protein affects the reaction [naringin results in increased phosphorylation of MAPK3 protein]
naringin results in increased activity of HRAS protein
CTD PMID:18296682, PMID:18951945 NCBI chr 1:214,178,404...214,181,841
Ensembl chr 1:214,178,407...214,181,686
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions
affects expression
ISO naringin inhibits the reaction [Glucose results in increased expression of ICAM1]; naringin inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; naringin inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]
naringin inhibits the reaction [OVAL protein results in increased expression of ICAM1 protein]
naringin affects the expression of ICAM1 mRNA
CTD PMID:22074828, PMID:24131540, PMID:25117567, PMID:25391245 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Ifng interferon gamma multiple interactions
affects expression
ISO naringin inhibits the reaction [[TNF protein co-treated with IFNG protein] affects the localization of RELA protein]; naringin inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased expression of CCL5 protein]
naringin inhibits the reaction [OVAL protein results in decreased expression of IFNG protein]
naringin affects the expression of IFNG mRNA
CTD PMID:16945185, PMID:21500970, PMID:24131540 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Igf1 insulin-like growth factor 1 affects expression
multiple interactions
increases expression
EXP
ISO
naringin affects the expression of IGF1 mRNA
naringin inhibits the reaction [Dexamethasone results in increased expression of IGF1 mRNA]
naringin results in increased expression of IGF1 mRNA
fulvestrant inhibits the reaction [naringin results in increased expression of IGF1 mRNA]
CTD PMID:23596885, PMID:24880026, PMID:30878453 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Il10 interleukin 10 multiple interactions
affects expression
EXP
ISO
naringin inhibits the reaction [Tobacco Smoke Pollution results in decreased expression of IL10 protein]
naringin affects the expression of IL10 protein
CTD PMID:22985397, PMID:25117567 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il1b interleukin 1 beta affects expression
multiple interactions
EXP
ISO
naringin affects the expression of IL1B mRNA
[bisphenol A co-treated with naringin] results in increased expression of IL1B protein; [naringin co-treated with Pioglitazone] inhibits the reaction [Quinolinic Acid results in increased expression of IL1B mRNA]; [NG-Nitroarginine Methyl Ester co-treated with bisphenol A co-treated with naringin] results in increased expression of IL1B protein; [NG-Nitroarginine Methyl Ester co-treated with naringin] results in increased expression of IL1B protein; naringin inhibits the reaction [[NG-Nitroarginine Methyl Ester co-treated with bisphenol A] results in increased expression of IL1B protein]; naringin inhibits the reaction [bisphenol A results in increased expression of IL1B protein]; naringin inhibits the reaction [NG-Nitroarginine Methyl Ester results in increased expression of IL1B protein]; naringin inhibits the reaction [Quinolinic Acid results in increased expression of IL1B mRNA]
naringin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL1B mRNA]; naringin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL1B protein]
naringin inhibits the reaction [OVAL protein results in increased expression of IL1B protein]
CTD PMID:24131540, PMID:24880026, PMID:30130594, PMID:32428650 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il2 interleukin 2 affects expression ISO naringin affects the expression of IL2 protein CTD PMID:25117567 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854
JBrowse link
G Il4 interleukin 4 affects expression
multiple interactions
ISO naringin affects the expression of IL4 protein
naringin inhibits the reaction [OVAL protein results in increased expression of IL4 protein]
CTD PMID:24131540, PMID:25117567 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Il6 interleukin 6 affects expression
multiple interactions
decreases expression
EXP
ISO
naringin affects the expression of IL6 mRNA
[naringin co-treated with Hesperidin] results in decreased expression of IL6 protein; [naringin co-treated with Pioglitazone] inhibits the reaction [Quinolinic Acid results in increased expression of IL6 mRNA]; naringin inhibits the reaction [Quinolinic Acid results in increased expression of IL6 mRNA]; naringin inhibits the reaction [TNF protein results in increased secretion of IL6 protein]
naringin results in decreased expression of IL6 protein
naringin affects the expression of IL6 protein
naringin inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; naringin inhibits the reaction [OVAL protein results in increased expression of IL6 protein]
naringin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 mRNA]; naringin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 protein]
CTD PMID:16137700, PMID:19810018, PMID:21820093, PMID:24131540, PMID:24880026, PMID:25117567, PMID:30130594 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Irs1 insulin receptor substrate 1 multiple interactions ISO naringin inhibits the reaction [Dietary Fats results in decreased phosphorylation of IRS1 protein] CTD PMID:22198281 NCBI chr 9:88,033,668...88,086,488
Ensembl chr 9:88,033,668...88,086,488
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [naringin promotes the reaction [JUN protein binds to BMP2 promoter]]; JUN protein affects the reaction [naringin results in increased expression of BMP2 mRNA]; JUN protein affects the reaction [naringin results in increased expression of BMP2 protein]; naringin promotes the reaction [JUN protein binds to BMP2 promoter]
naringin results in increased expression of JUN mRNA
CTD PMID:18495116 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Lcat lecithin cholesterol acyltransferase multiple interactions EXP naringin inhibits the reaction [Isoproterenol results in decreased activity of LCAT protein] CTD PMID:16906524 NCBI chr19:37,913,333...37,916,799
Ensembl chr19:37,913,336...37,916,813
JBrowse link
G Ldha lactate dehydrogenase A multiple interactions EXP naringin inhibits the reaction [Isoproterenol results in increased expression of LDHA protein] CTD PMID:17188415 NCBI chr 1:102,900,288...102,909,713
Ensembl chr 1:102,900,286...102,909,707
JBrowse link
G Ldhb lactate dehydrogenase B multiple interactions EXP naringin inhibits the reaction [Isoproterenol results in increased expression of LDHB protein] CTD PMID:17188415 NCBI chr 4:176,701,980...176,719,999
Ensembl chr 4:176,701,983...176,720,012
JBrowse link
G Lep leptin multiple interactions ISO
EXP
naringin inhibits the reaction [Dietary Fats results in increased expression of LEP protein]
[naringin co-treated with Hesperidin] results in decreased expression of LEP protein; naringin inhibits the reaction [Glucose results in increased expression of LEP protein]
CTD PMID:21820093, PMID:22198281, PMID:24399619 NCBI chr 4:56,337,695...56,351,818
Ensembl chr 4:56,337,695...56,351,818
JBrowse link
G Lepr leptin receptor multiple interactions ISO
EXP
naringin affects the reaction [LEPR protein affects the abundance of Glucose]; naringin affects the reaction [LEPR protein affects the activity of FASN protein]; naringin affects the reaction [LEPR protein affects the activity of G6PD protein]; naringin affects the reaction [LEPR protein affects the activity of HMGCR protein]; naringin affects the reaction [LEPR protein affects the expression of G6PC mRNA]; naringin affects the reaction [LEPR protein affects the expression of GCK mRNA]; naringin affects the reaction [LEPR protein affects the expression of PCK1 mRNA]; naringin affects the reaction [LEPR protein affects the expression of PPARG protein]; naringin affects the reaction [LEPR protein affects the expression of SLC2A2 protein]; naringin affects the reaction [LEPR protein affects the expression of SLC2A4 protein]
naringin inhibits the reaction [Glucose results in increased expression of LEPR protein]
CTD PMID:16427799, PMID:24399619 NCBI chr 5:120,503,475...120,682,281
Ensembl chr 5:120,564,645...120,682,221
JBrowse link
G Lpl lipoprotein lipase multiple interactions EXP naringin inhibits the reaction [Isoproterenol results in decreased activity of LPL protein] CTD PMID:16906524 NCBI chr16:22,537,687...22,561,487
Ensembl chr16:22,537,056...22,561,496
JBrowse link
G Maoa monoamine oxidase A multiple interactions EXP [NG-Nitroarginine Methyl Ester co-treated with bisphenol A co-treated with naringin] results in increased expression of MAOA protein; naringin inhibits the reaction [[NG-Nitroarginine Methyl Ester co-treated with bisphenol A] results in increased expression of MAOA protein] CTD PMID:32428650 NCBI chr  X:6,554,698...6,620,722
Ensembl chr  X:6,554,698...6,620,722
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
decreases phosphorylation
increases phosphorylation
ISO
EXP
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [naringin results in increased phosphorylation of MAPK1 protein]; HRAS protein affects the reaction [naringin results in increased phosphorylation of MAPK1 protein]; naringin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK1 protein]; RAF1 protein affects the reaction [naringin results in increased phosphorylation of MAPK1 protein]
naringin results in decreased phosphorylation of MAPK1 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [naringin results in increased phosphorylation of MAPK1 protein]; HRAS protein affects the reaction [naringin results in increased phosphorylation of MAPK1 protein]; RAF1 protein affects the reaction [naringin results in increased phosphorylation of MAPK1 protein]
naringin inhibits the reaction [Dietary Fats results in increased phosphorylation of MAPK1 protein]; naringin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of MAPK1 protein]; naringin inhibits the reaction [TNFSF11 protein results in increased phosphorylation of MAPK1 protein]
CTD PMID:18296682, PMID:18951945, PMID:21835177, PMID:22198281, PMID:22766066, PMID:22965302, PMID:25773745, PMID:26721195 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk10 mitogen activated protein kinase 10 multiple interactions ISO naringin inhibits the reaction [Dietary Fats results in increased phosphorylation of MAPK10 protein] CTD PMID:22198281 NCBI chr14:8,079,955...8,371,508
Ensembl chr14:8,080,275...8,368,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
decreases phosphorylation
increases phosphorylation
ISO
EXP
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [naringin results in increased phosphorylation of MAPK3 protein]; HRAS protein affects the reaction [naringin results in increased phosphorylation of MAPK3 protein]; naringin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK3 protein]; RAF1 protein affects the reaction [naringin results in increased phosphorylation of MAPK3 protein]
naringin results in decreased phosphorylation of MAPK3 protein
naringin inhibits the reaction [Dietary Fats results in increased phosphorylation of MAPK3 protein]; naringin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of MAPK3 protein]; naringin inhibits the reaction [TNFSF11 protein results in increased phosphorylation of MAPK3 protein]
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [naringin results in increased phosphorylation of MAPK3 protein]; HRAS protein affects the reaction [naringin results in increased phosphorylation of MAPK3 protein]; RAF1 protein affects the reaction [naringin results in increased phosphorylation of MAPK3 protein]
CTD PMID:18296682, PMID:18951945, PMID:21835177, PMID:22198281, PMID:22766066, PMID:22965302, PMID:25773745, PMID:26721195 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO naringin inhibits the reaction [Dietary Fats results in increased phosphorylation of MAPK8 protein] CTD PMID:22198281 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions ISO naringin inhibits the reaction [Dietary Fats results in increased phosphorylation of MAPK9 protein] CTD PMID:22198281 NCBI chr10:35,333,859...35,374,364
Ensembl chr10:35,333,859...35,374,355
JBrowse link
G Mir126b microRNA 126b increases expression
multiple interactions
ISO naringin results in increased expression of MIR126 mRNA
MIR126 mRNA affects the reaction [naringin results in decreased expression of VCAM1 mRNA]
CTD PMID:24975661 NCBI chr 3:4,042,488...4,042,560 JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions ISO naringin results in decreased expression of and results in decreased activity of MMP2 protein CTD PMID:26721195 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions ISO
EXP
naringin inhibits the reaction [Paraquat results in increased expression of MMP9 mRNA]; naringin inhibits the reaction [Paraquat results in increased expression of MMP9 protein]
naringin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; naringin results in decreased expression of and results in decreased activity of MMP9 protein
naringin inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of MMP9 protein]; naringin inhibits the reaction [TNF protein results in increased expression of MMP9 mRNA]; naringin inhibits the reaction [Tobacco Smoke Pollution results in increased expression of MMP9 protein]
CTD PMID:19810018, PMID:22985397, PMID:23603004, PMID:25866363, PMID:26721195 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Mpo myeloperoxidase multiple interactions EXP naringin inhibits the reaction [Tobacco Smoke Pollution results in increased activity of MPO protein] CTD PMID:22985397 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
JBrowse link
G Mt3 metallothionein 3 multiple interactions ISO naringin inhibits the reaction [Cadmium Chloride results in increased expression of MT3 protein] CTD PMID:28422390 NCBI chr19:11,324,708...11,326,112
Ensembl chr19:11,324,698...11,326,139
JBrowse link
G Mtor mechanistic target of rapamycin kinase multiple interactions EXP naringin inhibits the reaction [TNF protein results in increased phosphorylation of MTOR protein] CTD PMID:19810018 NCBI chr 5:165,263,813...165,373,967
Ensembl chr 5:165,263,800...165,373,967
JBrowse link
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming multiple interactions ISO naringin inhibits the reaction [EGF protein results in increased expression of MUC5AC mRNA]; naringin inhibits the reaction [EGF protein results in increased secretion of MUC5AC protein]
naringin inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased secretion of MUC5AC protein]
CTD PMID:22766066, PMID:31301536 NCBI chr 1:214,725,482...214,756,653 JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 multiple interactions
affects localization
EXP 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [naringin affects the localization of NFE2L2 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [naringin affects the localization of NFE2L2 protein]; [naringin co-treated with 3-nitropropionic acid] affects the localization of NFE2L2 protein; naringin inhibits the reaction [sodium arsenite results in decreased expression of NFE2L2 mRNA]; naringin promotes the reaction [[Oxygen deficiency co-treated with Oxygen] affects the localization of NFE2L2 protein]; rottlerin inhibits the reaction [naringin affects the localization of NFE2L2 protein] CTD PMID:22871521, PMID:25773745, PMID:27174133 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions EXP naringin inhibits the reaction [Cisplatin results in increased expression of NFKB1 mRNA] CTD PMID:26120027, PMID:26612654 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
JBrowse link
G Nfkbia NFKB inhibitor alpha affects degradation
multiple interactions
ISO naringin affects the degradation of NFKBIA protein
naringin inhibits the reaction [TNFSF11 protein results in increased degradation of NFKBIA protein]
CTD PMID:21835177, PMID:25117567 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Nos2 nitric oxide synthase 2 affects expression
multiple interactions
ISO
EXP
naringin affects the expression of NOS2 mRNA
naringin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]
naringin inhibits the reaction [3-nitropropionic acid results in increased expression of NOS2 mRNA]; naringin inhibits the reaction [Cisplatin results in increased expression of NOS2 mRNA]
CTD PMID:16137700, PMID:22871521, PMID:25117567, PMID:26612654 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nox4 NADPH oxidase 4 multiple interactions ISO naringin inhibits the reaction [TNF protein results in increased expression of NOX4 mRNA]; naringin inhibits the reaction [TNF protein results in increased expression of NOX4 protein] CTD PMID:25391245 NCBI chr 1:150,796,359...150,976,186
Ensembl chr 1:150,797,084...150,976,194
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions
increases expression
EXP [naringin co-treated with 3-nitropropionic acid] results in increased expression of NQO1 mRNA
naringin results in increased expression of NQO1 mRNA
CTD PMID:22871521 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Ogdh oxoglutarate dehydrogenase multiple interactions EXP naringin inhibits the reaction [Isoproterenol results in decreased activity of OGDH protein] CTD PMID:17994577 NCBI chr14:86,414,924...86,481,903
Ensembl chr14:86,414,949...86,613,327
JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 multiple interactions ISO naringin affects the reaction [LEPR protein affects the expression of PCK1 mRNA] CTD PMID:16427799 NCBI chr 3:171,213,936...171,219,885
Ensembl chr 3:171,213,936...171,219,871
JBrowse link
G Pde5a phosphodiesterase 5A multiple interactions EXP naringin inhibits the reaction [[NG-Nitroarginine Methyl Ester co-treated with bisphenol A] results in increased activity of PDE5A protein]; naringin inhibits the reaction [bisphenol A results in increased activity of PDE5A protein]; naringin inhibits the reaction [NG-Nitroarginine Methyl Ester results in increased activity of PDE5A protein] CTD PMID:32428650 NCBI chr 2:226,899,604...227,044,916
Ensembl chr 2:226,900,619...227,041,576
JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha multiple interactions ISO naringin inhibits the reaction [Dexamethasone results in increased expression of PIK3CA mRNA] CTD PMID:30878453 NCBI chr 2:118,831,350...118,861,456
Ensembl chr 2:118,831,350...118,861,454
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 multiple interactions ISO naringin inhibits the reaction [Dexamethasone results in increased expression of PIK3R1 mRNA] CTD PMID:30878453 NCBI chr 2:31,742,326...31,826,882
Ensembl chr 2:31,745,088...31,826,867
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO naringin inhibits the reaction [Dietary Fats results in decreased expression of PPARA mRNA] CTD PMID:22198281 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO
EXP
naringin affects the reaction [LEPR protein affects the expression of PPARG protein]; naringin inhibits the reaction [Dietary Fats results in increased expression of PPARG mRNA]
[naringin co-treated with Pioglitazone] inhibits the reaction [Quinolinic Acid results in decreased expression of PPARG mRNA]; naringin inhibits the reaction [Quinolinic Acid results in decreased expression of PPARG mRNA]
CTD PMID:16427799, PMID:22198281, PMID:30130594 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha multiple interactions EXP naringin inhibits the reaction [Ethanol results in increased expression of PPARGC1A mRNA] CTD PMID:18793633 NCBI chr14:63,095,291...63,190,688
Ensembl chr14:63,095,720...63,187,009
JBrowse link
G Prkcd protein kinase C, delta increases phosphorylation
multiple interactions
EXP naringin results in increased phosphorylation of PRKCD protein
rottlerin inhibits the reaction [naringin results in increased phosphorylation of PRKCD protein]
CTD PMID:25773745 NCBI chr16:6,655,131...6,675,746
Ensembl chr16:6,655,120...6,675,746
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 affects expression
multiple interactions
ISO
EXP
naringin affects the expression of PTGS2 mRNA; naringin affects the expression of PTGS2 protein
naringin inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; naringin inhibits the reaction [OVAL protein results in increased expression of PTGS2 protein]
naringin inhibits the reaction [3-nitropropionic acid results in increased expression of PTGS2 mRNA]
CTD PMID:16137700, PMID:22871521, PMID:24131540, PMID:25117567 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase multiple interactions
increases activity
increases phosphorylation
ISO
EXP
RAF1 protein affects the reaction [naringin results in increased expression of CDKN1A protein]; RAF1 protein affects the reaction [naringin results in increased phosphorylation of MAPK1 protein]; RAF1 protein affects the reaction [naringin results in increased phosphorylation of MAPK3 protein]
RAF1 protein affects the reaction [naringin results in decreased expression of CDK2 protein]; RAF1 protein affects the reaction [naringin results in decreased expression of CDK4 protein]; RAF1 protein affects the reaction [naringin results in increased expression of CDKN1A protein]; RAF1 protein affects the reaction [naringin results in increased phosphorylation of MAPK1 protein]; RAF1 protein affects the reaction [naringin results in increased phosphorylation of MAPK3 protein]
naringin results in increased activity of RAF1 protein
naringin results in increased phosphorylation of RAF1 protein
CTD PMID:18296682, PMID:18951945 NCBI chr 4:147,532,040...147,592,769
Ensembl chr 4:147,532,042...147,592,699
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO naringin inhibits the reaction [[TNF protein co-treated with IFNG protein] affects the localization of RELA protein]; naringin inhibits the reaction [EGF protein affects the localization of RELA protein]
naringin affects the expression of and affects the activity of RELA protein; naringin inhibits the reaction [lipopolysaccharide, E coli O55-B5 affects the localization of RELA protein]
CTD PMID:21500970, PMID:22766066, PMID:22965302, PMID:25117567 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 multiple interactions EXP naringin inhibits the reaction [AICA ribonucleotide results in increased phosphorylation of RPS6KB1 protein]; naringin inhibits the reaction [cyanoginosin LR results in increased phosphorylation of RPS6KB1 protein]; naringin inhibits the reaction [Okadaic Acid results in increased phosphorylation of RPS6KB1 protein]; naringin inhibits the reaction [TNF protein results in increased phosphorylation of RPS6KB1 protein] CTD PMID:15342961, PMID:19810018 NCBI chr10:73,824,200...73,865,503
Ensembl chr10:73,824,202...73,865,364
JBrowse link
G Runx2 RUNX family transcription factor 2 increases expression
multiple interactions
ISO
EXP
naringin results in increased expression of RUNX2 mRNA
naringin inhibits the reaction [Dexamethasone results in decreased expression of RUNX2 protein]
DKK1 protein inhibits the reaction [naringin inhibits the reaction [Hydrogen Peroxide results in decreased expression of RUNX2 mRNA]]; naringin inhibits the reaction [Hydrogen Peroxide results in decreased expression of RUNX2 mRNA]
fulvestrant inhibits the reaction [naringin results in increased expression of RUNX2 mRNA]
CTD PMID:21741227, PMID:23596885, PMID:24915843, PMID:26482937, PMID:30878453 NCBI chr 9:18,564,743...18,773,092
Ensembl chr 9:18,564,927...18,773,092
JBrowse link
G Sirt1 sirtuin 1 multiple interactions EXP naringin inhibits the reaction [Ethanol results in increased expression of SIRT1 mRNA] CTD PMID:18793633 NCBI chr20:26,831,971...26,851,587
Ensembl chr20:26,833,357...26,852,199
JBrowse link
G Slc2a2 solute carrier family 2 member 2 multiple interactions ISO naringin affects the reaction [LEPR protein affects the expression of SLC2A2 protein] CTD PMID:16427799 NCBI chr 2:114,413,427...114,445,418
Ensembl chr 2:114,413,410...114,445,395
JBrowse link
G Slc2a4 solute carrier family 2 member 4 multiple interactions ISO naringin affects the reaction [LEPR protein affects the expression of SLC2A4 protein] CTD PMID:16427799 NCBI chr10:56,552,921...56,558,562
Ensembl chr10:56,552,983...56,558,487
JBrowse link
G Slco1a4 solute carrier organic anion transporter family, member 1a4 multiple interactions ISO naringin inhibits the reaction [SLCO1A2 protein alternative form results in increased uptake of estrone sulfate]; naringin inhibits the reaction [SLCO1A2 protein results in increased transport of estrone sulfate]; naringin inhibits the reaction [SLCO1A2 protein results in increased uptake of Quercetin]; naringin inhibits the reaction [SLCO1A2 protein results in increased uptake of Quinine] CTD PMID:24947867, PMID:25466967, PMID:27504015 NCBI chr 4:175,969,549...176,026,227
Ensembl chr 4:175,969,549...176,026,163
JBrowse link
G Slco1b2 solute carrier organic anion transporter family member 1B2 multiple interactions ISO naringin inhibits the reaction [SLCO1B3 protein results in increased import of Sulfobromophthalein]; naringin inhibits the reaction [SLCO1B3 protein results in increased uptake of Hydroxyurea] CTD PMID:21256917, PMID:22394605 NCBI chr 4:175,814,118...175,881,775
Ensembl chr 4:175,814,118...175,881,768
JBrowse link
G Smad3 SMAD family member 3 multiple interactions EXP naringin inhibits the reaction [sodium arsenite results in increased expression of SMAD3 mRNA] CTD PMID:27174133 NCBI chr 8:68,569,530...68,678,349
Ensembl chr 8:68,569,530...68,678,349
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions ISO naringin inhibits the reaction [Ferric Compounds results in decreased activity of SOD2 protein] CTD PMID:21345335 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Sp7 Sp7 transcription factor increases expression
multiple interactions
EXP
ISO
naringin results in increased expression of SP7 mRNA
naringin inhibits the reaction [Hydrogen Peroxide results in decreased expression of SP7 mRNA]
fulvestrant inhibits the reaction [naringin results in increased expression of SP7 mRNA]
CTD PMID:23596885, PMID:26482937 NCBI chr 7:143,957,316...143,967,488
Ensembl chr 7:143,958,858...143,967,484
JBrowse link
G Spn sialophorin multiple interactions
decreases expression
EXP [bisphenol A co-treated with naringin] results in decreased expression of SPN protein; [NG-Nitroarginine Methyl Ester co-treated with bisphenol A co-treated with naringin] results in decreased expression of SPN protein; [NG-Nitroarginine Methyl Ester co-treated with naringin] results in decreased expression of SPN protein; naringin inhibits the reaction [[NG-Nitroarginine Methyl Ester co-treated with bisphenol A] results in increased expression of SPN protein]; naringin inhibits the reaction [bisphenol A results in increased expression of SPN protein]; naringin inhibits the reaction [NG-Nitroarginine Methyl Ester results in increased expression of SPN protein]
naringin results in decreased expression of SPN protein
CTD PMID:32428650 NCBI chr 1:198,572,999...198,585,664
Ensembl chr 1:198,572,999...198,577,226
JBrowse link
G Spp1 secreted phosphoprotein 1 increases expression
increases secretion
multiple interactions
ISO
EXP
naringin results in increased expression of SPP1 mRNA; naringin results in increased expression of SPP1 protein
naringin results in increased secretion of SPP1 protein
fulvestrant inhibits the reaction [naringin results in increased secretion of SPP1 protein]
CTD PMID:18495116, PMID:23596885, PMID:24915843 NCBI chr14:6,673,686...6,679,965
Ensembl chr14:6,673,686...6,679,901
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 multiple interactions ISO naringin inhibits the reaction [Dietary Fats results in increased expression of SREBF1 mRNA] CTD PMID:22198281 NCBI chr10:46,570,996...46,593,021
Ensembl chr10:46,570,996...46,593,009
JBrowse link
G Stat3 signal transducer and activator of transcription 3 affects expression ISO naringin affects the expression of STAT3 mRNA; naringin affects the expression of STAT3 protein CTD PMID:25117567 NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions
affects expression
ISO
EXP
naringin inhibits the reaction [Paraquat results in increased expression of TGFB1 mRNA]
naringin inhibits the reaction [sodium arsenite results in increased expression of TGFB1 mRNA]
naringin affects the expression of TGFB1 mRNA
CTD PMID:23603004, PMID:25117567, PMID:27174133 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 multiple interactions ISO naringin inhibits the reaction [Paraquat results in increased expression of TIMP1 mRNA]; naringin inhibits the reaction [Paraquat results in increased expression of TIMP1 protein] CTD PMID:23603004 NCBI chr  X:1,364,771...1,369,451
Ensembl chr  X:1,364,786...1,369,384
JBrowse link
G Tnf tumor necrosis factor multiple interactions
affects expression
ISO
EXP
naringin inhibits the reaction [Dietary Fats results in increased expression of TNF protein]; naringin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; naringin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF]; naringin inhibits the reaction [Paraquat results in increased expression of TNF mRNA]
[naringin co-treated with Pioglitazone] inhibits the reaction [Quinolinic Acid results in increased expression of TNF mRNA]; naringin inhibits the reaction [3-nitropropionic acid results in increased expression of TNF mRNA]; naringin inhibits the reaction [[NG-Nitroarginine Methyl Ester co-treated with bisphenol A] results in increased expression of TNF protein]; naringin inhibits the reaction [bisphenol A results in increased expression of TNF protein]; naringin inhibits the reaction [Cisplatin results in increased expression of TNF mRNA]; naringin inhibits the reaction [Cisplatin results in increased expression of TNF protein]; naringin inhibits the reaction [NG-Nitroarginine Methyl Ester results in increased expression of TNF protein]; naringin inhibits the reaction [Quinolinic Acid results in increased expression of TNF mRNA]; naringin inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of MMP9 protein]; naringin inhibits the reaction [TNF protein results in increased expression of MMP9 mRNA]; naringin inhibits the reaction [TNF protein results in increased phosphorylation of AKT1 protein]; naringin inhibits the reaction [TNF protein results in increased phosphorylation of MTOR protein]; naringin inhibits the reaction [TNF protein results in increased phosphorylation of RPS6KB1 protein]; naringin inhibits the reaction [TNF protein results in increased secretion of CXCL8 protein]; naringin inhibits the reaction [TNF protein results in increased secretion of IL6 protein]; naringin inhibits the reaction [Tobacco Smoke Pollution results in increased expression of TNF protein]
naringin affects the expression of TNF protein
naringin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF mRNA]; naringin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF protein]; naringin inhibits the reaction [[TNF protein co-treated with IFNG protein] affects the localization of RELA protein]; naringin inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased expression of CCL5 protein]; naringin inhibits the reaction [TNF protein results in increased expression of CYBA mRNA]; naringin inhibits the reaction [TNF protein results in increased expression of CYBA protein]; naringin inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; naringin inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]; naringin inhibits the reaction [TNF protein results in increased expression of NOX4 mRNA]; naringin inhibits the reaction [TNF protein results in increased expression of NOX4 protein]; naringin inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA]; naringin inhibits the reaction [TNF protein results in increased expression of VCAM1 protein]
naringin affects the expression of TNF mRNA
CTD PMID:16137700, PMID:19810018, PMID:21500970, PMID:22198281, PMID:22871521, PMID:22985397, PMID:23603004, PMID:24131540, PMID:24880026, PMID:25117567, PMID:25391245, PMID:26120027, PMID:26612654, PMID:30130594, PMID:32428650 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfrsf11a TNF receptor superfamily member 11A decreases expression ISO naringin results in decreased expression of TNFRSF11A mRNA CTD PMID:24376342 NCBI chr13:25,778,306...25,835,802
Ensembl chr13:25,778,317...25,835,957
JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11B multiple interactions ISO naringin inhibits the reaction [Dexamethasone results in decreased expression of TNFRSF11B protein]; naringin inhibits the reaction [Dexamethasone results in increased expression of TNFRSF11B protein] CTD PMID:30878453 NCBI chr 7:93,798,580...93,826,586
Ensembl chr 7:93,798,545...93,826,665
JBrowse link
G Tnfsf11 TNF superfamily member 11 multiple interactions ISO naringin inhibits the reaction [[TNFSF11 protein co-treated with CSF1R protein] results in increased expression of ACP5 mRNA]; naringin inhibits the reaction [[TNFSF11 protein co-treated with CSF1R protein] results in increased expression of ATP6V0D2 mRNA]; naringin inhibits the reaction [[TNFSF11 protein co-treated with CSF1R protein] results in increased expression of CALCR mRNA]; naringin inhibits the reaction [[TNFSF11 protein co-treated with CSF1R protein] results in increased expression of CTSK mRNA]; naringin inhibits the reaction [TNFSF11 protein results in increased degradation of NFKBIA protein]; naringin inhibits the reaction [TNFSF11 protein results in increased phosphorylation of MAPK1 protein]; naringin inhibits the reaction [TNFSF11 protein results in increased phosphorylation of MAPK3 protein] CTD PMID:21835177 NCBI chr15:60,482,527...60,512,704
Ensembl chr15:60,482,527...60,512,704
JBrowse link
G Tnnt2 troponin T2, cardiac type multiple interactions EXP naringin inhibits the reaction [Isoproterenol results in increased expression of TNNT2 protein] CTD PMID:17188415 NCBI chr13:52,662,974...52,680,992
Ensembl chr13:52,662,996...52,680,990
JBrowse link
G Tp53 tumor protein p53 increases expression
decreases expression
multiple interactions
ISO
EXP
naringin results in increased expression of TP53 mRNA
naringin results in decreased expression of TP53 protein
[bisphenol A co-treated with naringin] results in decreased expression of TP53 protein; [NG-Nitroarginine Methyl Ester co-treated with naringin] results in decreased expression of TP53 protein; naringin inhibits the reaction [[NG-Nitroarginine Methyl Ester co-treated with bisphenol A] results in increased expression of TP53 protein]; naringin inhibits the reaction [Cisplatin results in increased expression of TP53 mRNA]; naringin inhibits the reaction [NG-Nitroarginine Methyl Ester results in increased expression of TP53 protein]
CTD PMID:22847135, PMID:26120027, PMID:26612654, PMID:32428650 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Tslp thymic stromal lymphopoietin multiple interactions ISO naringin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TSLP mRNA]; naringin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TSLP protein]
naringin inhibits the reaction [OVAL protein results in increased expression of TSLP protein]
CTD PMID:24131540 NCBI chr18:25,613,601...25,618,066
Ensembl chr18:25,613,831...25,617,361
JBrowse link
G Ucp2 uncoupling protein 2 multiple interactions ISO naringin inhibits the reaction [Dietary Fats results in increased expression of UCP2 mRNA] CTD PMID:22198281 NCBI chr 1:165,506,375...165,512,744
Ensembl chr 1:165,506,361...165,512,744
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions
decreases expression
ISO MIR126 mRNA affects the reaction [naringin results in decreased expression of VCAM1 mRNA]; naringin inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA]; naringin inhibits the reaction [TNF protein results in increased expression of VCAM1 protein]
naringin results in decreased expression of VCAM1 mRNA; naringin results in decreased expression of VCAM1 protein
CTD PMID:24975661, PMID:25391245 NCBI chr 2:219,071,193...219,090,931
Ensembl chr 2:219,071,193...219,097,619
JBrowse link
G Vegfc vascular endothelial growth factor C affects expression EXP naringin affects the expression of VEGFC mRNA CTD PMID:24880026 NCBI chr16:40,440,371...40,555,178
Ensembl chr16:40,440,207...40,555,576
JBrowse link
O-methyleugenol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aass aminoadipate-semialdehyde synthase decreases expression ISO methyleugenol results in decreased expression of AASS mRNA CTD PMID:32234424 NCBI chr 4:50,152,005...50,208,935
Ensembl chr 4:50,152,452...50,200,328
JBrowse link
G Abat 4-aminobutyrate aminotransferase decreases expression ISO methyleugenol results in decreased expression of ABAT mRNA CTD PMID:32234424 NCBI chr10:7,093,406...7,200,439
Ensembl chr10:7,093,405...7,200,499
JBrowse link
G Abca1 ATP binding cassette subfamily A member 1 decreases expression ISO methyleugenol results in decreased expression of ABCA1 mRNA CTD PMID:32234424 NCBI chr 5:69,857,717...69,983,042
Ensembl chr 5:69,857,771...69,983,015
JBrowse link
G Abca6 ATP binding cassette subfamily A member 6 decreases expression ISO methyleugenol results in decreased expression of ABCA6 mRNA CTD PMID:32234424 NCBI chr10:98,477,716...98,546,699
Ensembl chr10:98,478,067...98,544,447
JBrowse link
G Abcb11 ATP binding cassette subfamily B member 11 decreases expression ISO methyleugenol results in decreased expression of ABCB11 mRNA CTD PMID:32234424 NCBI chr 3:55,480,024...55,587,946
Ensembl chr 3:55,480,024...55,587,946
JBrowse link
G Abcb4 ATP binding cassette subfamily B member 4 decreases expression ISO methyleugenol results in decreased expression of ABCB4 mRNA CTD PMID:32234424 NCBI chr 4:22,133,984...22,192,687
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcc6 ATP binding cassette subfamily C member 6 decreases expression ISO methyleugenol results in decreased expression of ABCC6 mRNA CTD PMID:32234424 NCBI chr 1:101,954,786...102,013,252
Ensembl chr 1:101,959,540...102,013,243
JBrowse link
G Abcc9 ATP binding cassette subfamily C member 9 decreases expression ISO methyleugenol results in decreased expression of ABCC9 mRNA CTD PMID:32234424 NCBI chr 4:176,806,098...176,928,540
Ensembl chr 4:176,805,431...176,922,424
JBrowse link
G Abcg5 ATP binding cassette subfamily G member 5 decreases expression ISO methyleugenol results in decreased expression of ABCG5 mRNA CTD PMID:32234424 NCBI chr 6:7,935,771...7,961,207
Ensembl chr 6:7,935,771...7,961,207
JBrowse link
G Abcg8 ATP binding cassette subfamily G member 8 decreases expression ISO methyleugenol results in decreased expression of ABCG8 mRNA CTD PMID:32234424 NCBI chr 6:7,961,413...7,980,708
Ensembl chr 6:7,961,413...7,980,708
JBrowse link
G Abhd2 abhydrolase domain containing 2, acylglycerol lipase decreases expression ISO methyleugenol results in decreased expression of ABHD2 mRNA CTD PMID:32234424 NCBI chr 1:140,998,240...141,087,405
Ensembl chr 1:140,998,240...141,087,405
JBrowse link
G Acaa1a acetyl-CoA acyltransferase 1A decreases expression ISO methyleugenol results in decreased expression of ACAA1 mRNA CTD PMID:32234424 NCBI chr 8:128,027,880...128,036,471
Ensembl chr 8:128,027,958...128,036,236
JBrowse link
G Acacb acetyl-CoA carboxylase beta decreases expression ISO methyleugenol results in decreased expression of ACACB mRNA CTD PMID:32234424 NCBI chr12:48,127,149...48,238,969
Ensembl chr12:48,127,149...48,238,887
JBrowse link
G Acat2 acetyl-CoA acetyltransferase 2 decreases expression ISO methyleugenol results in decreased expression of ACAT2 mRNA CTD PMID:32234424 NCBI chr 1:47,972,399...47,992,654
Ensembl chr 1:47,972,399...47,992,653
JBrowse link
G Ache acetylcholinesterase increases expression ISO methyleugenol results in increased expression of ACHE mRNA CTD PMID:32234424 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
JBrowse link
G Acmsd aminocarboxymuconate semialdehyde decarboxylase decreases expression ISO methyleugenol results in decreased expression of ACMSD mRNA CTD PMID:32234424 NCBI chr13:44,424,689...44,468,734
Ensembl chr13:44,424,689...44,468,734
JBrowse link
G Acot1 acyl-CoA thioesterase 1 decreases expression ISO methyleugenol results in decreased expression of ACOT1 mRNA CTD PMID:32234424 NCBI chr 6:107,485,088...107,493,082
Ensembl chr 6:107,485,249...107,493,798
JBrowse link
G Acot11 acyl-CoA thioesterase 11 decreases expression ISO methyleugenol results in decreased expression of ACOT11 mRNA CTD PMID:32234424 NCBI chr 5:126,347,478...126,395,655
Ensembl chr 5:126,347,435...126,395,668
JBrowse link
G Acot12 acyl-CoA thioesterase 12 decreases expression ISO methyleugenol results in decreased expression of ACOT12 mRNA CTD PMID:32234424 NCBI chr 2:20,857,056...20,901,656
Ensembl chr 2:20,857,202...20,901,659
JBrowse link
G Acox2 acyl-CoA oxidase 2 decreases expression ISO methyleugenol results in decreased expression of ACOX2 mRNA CTD PMID:32234424 NCBI chr15:18,449,304...18,481,472
Ensembl chr15:18,451,144...18,481,470
JBrowse link
G Acsl1 acyl-CoA synthetase long-chain family member 1 decreases expression ISO methyleugenol results in decreased expression of ACSL1 mRNA CTD PMID:32234424 NCBI chr16:48,937,456...49,003,898
Ensembl chr16:48,937,456...49,003,246
JBrowse link
G Acsl4 acyl-CoA synthetase long-chain family member 4 decreases expression ISO methyleugenol results in decreased expression of ACSL4 mRNA CTD PMID:32234424 NCBI chr  X:113,596,247...113,660,024
Ensembl chr  X:113,596,239...113,659,944
JBrowse link
G Acsl5 acyl-CoA synthetase long-chain family member 5 decreases expression ISO methyleugenol results in decreased expression of ACSL5 mRNA CTD PMID:32234424 NCBI chr 1:276,240,703...276,290,012
Ensembl chr 1:276,240,703...276,290,008
JBrowse link
G Acsm2 acyl-CoA synthetase medium-chain family member 2 decreases expression ISO methyleugenol results in decreased expression of ACSM2A mRNA CTD PMID:32234424 NCBI chr 1:189,289,957...189,329,007
Ensembl chr 1:189,289,957...189,395,276
JBrowse link
G Acsm3 acyl-CoA synthetase medium-chain family member 3 decreases expression ISO methyleugenol results in decreased expression of ACSM3 mRNA CTD PMID:32234424 NCBI chr 1:189,514,504...189,541,233
Ensembl chr 1:189,514,553...189,541,224
JBrowse link
G Acsm5 acyl-CoA synthetase medium-chain family member 5 decreases expression ISO methyleugenol results in decreased expression of ACSM5 mRNA CTD PMID:32234424 NCBI chr 1:189,240,955...189,270,422
Ensembl chr 1:189,233,141...189,272,172
JBrowse link
G Acss1 acyl-CoA synthetase short-chain family member 1 decreases expression ISO methyleugenol results in decreased expression of ACSS1 mRNA CTD PMID:32234424 NCBI chr 3:146,420,346...146,470,293
Ensembl chr 3:146,420,346...146,470,293
JBrowse link
G Acss2 acyl-CoA synthetase short-chain family member 2 decreases expression ISO methyleugenol results in decreased expression of ACSS2 mRNA CTD PMID:32234424 NCBI chr 3:151,032,925...151,075,856
Ensembl chr 3:151,032,952...151,075,856
JBrowse link
G Actl10 actin-like 10 increases expression ISO methyleugenol results in increased expression of ACTL10 mRNA CTD PMID:32234424 NCBI chr 3:150,054,085...150,056,869
Ensembl chr 3:150,055,749...150,056,789
JBrowse link
G Acyp2 acylphosphatase 2 decreases expression ISO methyleugenol results in decreased expression of ACYP2 mRNA CTD PMID:32234424 NCBI chr14:114,891,245...115,052,497
Ensembl chr14:114,891,246...115,052,450
JBrowse link
G Adam19 ADAM metallopeptidase domain 19 increases expression ISO methyleugenol results in increased expression of ADAM19 mRNA CTD PMID:32234424 NCBI chr10:31,146,107...31,240,582
Ensembl chr10:31,146,107...31,240,582
JBrowse link
G Adamts17 ADAM metallopeptidase with thrombospondin type 1 motif, 17 decreases expression ISO methyleugenol results in decreased expression of ADAMTS17 mRNA CTD PMID:32234424 NCBI chr 1:127,802,872...128,126,764
Ensembl chr 1:127,802,978...128,124,171
JBrowse link
G Adamts3 ADAM metallopeptidase with thrombospondin type 1, motif 3 decreases expression ISO methyleugenol results in decreased expression of ADAMTS3 mRNA CTD PMID:32234424 NCBI chr14:19,866,278...20,072,896
Ensembl chr14:19,866,408...20,070,994
JBrowse link
G Adamts6 ADAM metallopeptidase with thrombospondin type 1 motif, 6 decreases expression ISO methyleugenol results in decreased expression of ADAMTS6 mRNA CTD PMID:32234424 NCBI chr 2:34,374,142...34,589,676
Ensembl chr 2:34,374,158...34,586,755
JBrowse link
G Adamtsl3 ADAMTS-like 3 decreases expression ISO methyleugenol results in decreased expression of ADAMTSL3 mRNA CTD PMID:32234424 NCBI chr 1:144,238,958...144,561,065
Ensembl chr 1:144,239,020...144,561,247
JBrowse link
G Adarb2 adenosine deaminase, RNA-specific, B2 decreases expression ISO methyleugenol results in decreased expression of ADARB2 mRNA CTD PMID:32234424 NCBI chr17:58,098,979...58,653,137
Ensembl chr17:58,104,559...58,301,260
JBrowse link
G Adcy5 adenylate cyclase 5 decreases expression ISO methyleugenol results in decreased expression of ADCY5 mRNA CTD PMID:32234424 NCBI chr11:68,695,839...68,842,452
Ensembl chr11:68,695,839...68,842,320
JBrowse link
G Adcy8 adenylate cyclase 8 decreases expression ISO methyleugenol results in decreased expression of ADCY8 mRNA CTD PMID:32234424 NCBI chr 7:105,353,883...105,593,372
Ensembl chr 7:105,353,913...105,592,804
JBrowse link
G Adgrf4 adhesion G protein-coupled receptor F4 increases expression ISO methyleugenol results in increased expression of ADGRF4 mRNA CTD PMID:32234424 NCBI chr 9:20,951,249...20,982,493
Ensembl chr 9:20,951,260...20,982,487
JBrowse link
G Adgrg1 adhesion G protein-coupled receptor G1 increases expression ISO methyleugenol results in increased expression of ADGRG1 mRNA CTD PMID:32234424 NCBI chr19:10,423,534...10,460,674
Ensembl chr19:10,423,501...10,460,674
JBrowse link
G Adgrg7 adhesion G protein-coupled receptor G7 decreases expression ISO methyleugenol results in decreased expression of ADGRG7 mRNA CTD PMID:32234424 NCBI chr11:46,103,173...46,172,303
Ensembl chr11:46,793,777...46,856,291
Ensembl chr11:46,793,777...46,856,291
JBrowse link
G