Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:fenbendazole
go back to main search page
Accession:CHEBI:77092 term browser browse the term
Definition:A member of the class of benzimidazoles that is 1H-benzimidazole which is substituted at positons 2 and 5 by (methoxycarbonyl)amino and phenylsulfanediyl groups, respectively. A broad-spectrum anthelmintic, it is used, particularly in veterinary medicine, for the treatment of nematodal infections.
Synonyms:exact_synonym: methyl [5-(phenylsulfanyl)-1H-benzimidazol-2-yl]carbamate
 related_synonym: 2-(methoxycarbonylamino)-5-(phenylthio)benzimidazole;   5-(phenylthio)-2-benzimidazolecarbamic acid methyl ester;   Formula=C15H13N3O2S;   Hoe 881v;   InChI=1S/C15H13N3O2S/c1-20-15(19)18-14-16-12-8-7-11(9-13(12)17-14)21-10-5-3-2-4-6-10/h2-9H,1H3,(H2,16,17,18,19);   InChIKey=HDDSHPAODJUKPD-UHFFFAOYSA-N;   Panacur;   SMILES=COC(=O)Nc1nc2cc(Sc3ccccc3)ccc2[nH]1;   Safe-quard;   [5-(phenylthio)-1H-benzimidazol-2-yl]carbamic acid methyl ester;   fenbendazol;   fenbendazolum;   methyl 5-(phenylthio)-2-benzimidazolecarbamate;   methyl [5-(phenylthio)-1H-benzimidazol-2-yl]carbamate
 xref: CAS:43210-67-9 "ChemIDplus";   Drug_Central:4536 "DrugCentral";   HMDB:HMDB0029745;   KEGG:D04140;   LINCS:LSM-3134
 xref_mesh: MESH:D005273
 xref: PMID:22048645 "Europe PMC";   PMID:23488766 "Europe PMC";   PMID:23959307 "Europe PMC";   PMID:24183965 "Europe PMC";   Patent:DE2164690;   Patent:US3954791;   Reaxys:759077 "Reaxys";   VSDB:1758;   Wikipedia:Fenbendazole


show annotations for term's descendants       view all columns           Sort by:
 
fenbendazole term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aurkb aurora kinase B JBrowse link 10 55,625,860 55,632,399 RGD:6480464
G Cbx5 chromobox 5 JBrowse link 7 144,819,673 144,865,014 RGD:6480464
G Ccl2 C-C motif chemokine ligand 2 JBrowse link 10 69,412,065 69,413,863 RGD:6480464
G Ccnd1 cyclin D1 JBrowse link 1 218,090,750 218,100,447 RGD:6480464
G Ccne2 cyclin E2 JBrowse link 5 24,434,077 24,446,406 RGD:6480464
G Cdk1 cyclin-dependent kinase 1 JBrowse link 20 20,576,341 20,591,510 RGD:6480464
G Cdkn1a cyclin-dependent kinase inhibitor 1A JBrowse link 20 6,348,422 6,358,864 RGD:6480464
G Cdkn2a cyclin-dependent kinase inhibitor 2A JBrowse link 5 107,823,323 107,832,405 RGD:6480464
G Cdkn2b cyclin-dependent kinase inhibitor 2B JBrowse link 5 107,834,353 107,857,428 RGD:6480464
G Cdr2 cerebellar degeneration-related protein 2 JBrowse link 1 190,889,698 190,914,606 RGD:6480464
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 JBrowse link 8 62,451,360 62,458,244 RGD:6480464
G Gstp1 glutathione S-transferase pi 1 JBrowse link 1 219,291,679 219,294,147 RGD:6480464
G Il6r interleukin 6 receptor JBrowse link 2 189,196,180 189,255,987 RGD:6480464
G Incenp inner centromere protein JBrowse link 1 225,923,448 225,953,384 RGD:6480464
G Mapt microtubule-associated protein tau JBrowse link 10 92,289,002 92,386,517 RGD:6480464
G Mdm2 MDM2 proto-oncogene JBrowse link 7 60,719,060 60,743,618 RGD:6480464
G Mki67 marker of proliferation Ki-67 JBrowse link 1 207,993,895 208,020,454 RGD:6480464
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 JBrowse link 7 30,003,429 30,162,095 RGD:6480464
G Tmem70 transmembrane protein 70 JBrowse link 5 2,019,852 2,037,038 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:6480464
G Ube2e2 ubiquitin-conjugating enzyme E2E 2 JBrowse link 15 7,402,210 7,928,320 RGD:6480464
G Vegfa vascular endothelial growth factor A JBrowse link 9 17,340,341 17,355,681 RGD:6480464
G Wee1 WEE1 G2 checkpoint kinase JBrowse link 1 174,765,228 174,790,882 RGD:6480464
oxfendazole term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcg2 ATP binding cassette subfamily G member 2 JBrowse link 4 88,765,441 88,890,268 RGD:6480464
G Akr7a3 aldo-keto reductase family 7 member A3 JBrowse link 5 157,801,120 157,813,756 RGD:6480464
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:6480464
G Cdkn1a cyclin-dependent kinase inhibitor 1A JBrowse link 20 6,348,422 6,358,864 RGD:6480464
G Chek1 checkpoint kinase 1 JBrowse link 8 39,181,162 39,201,588 RGD:6480464
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 JBrowse link 8 62,472,087 62,478,122 RGD:6480464
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 JBrowse link 8 62,451,360 62,458,244 RGD:6480464
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 JBrowse link 1 83,103,925 83,119,578 RGD:6480464
G Gpx2 glutathione peroxidase 2 JBrowse link 6 99,839,960 99,843,245 RGD:6480464
G Gsta5 glutathione S-transferase alpha 5 JBrowse link 8 85,553,659 85,564,914 RGD:6480464
G Gstm1 glutathione S-transferase mu 1 JBrowse link 2 210,803,869 210,809,461 RGD:6480464
G Mad2l1 mitotic arrest deficient 2 like 1 JBrowse link 4 97,530,993 97,543,179 RGD:6480464
G Mdm2 MDM2 proto-oncogene JBrowse link 7 60,719,060 60,743,618 RGD:6480464
G Me1 malic enzyme 1 JBrowse link 8 94,256,830 94,368,834 RGD:6480464
G Mki67 marker of proliferation Ki-67 JBrowse link 1 207,993,895 208,020,454 RGD:6480464
G Nqo1 NAD(P)H quinone dehydrogenase 1 JBrowse link 19 38,422,210 38,437,103 RGD:6480464
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 JBrowse link 7 30,003,429 30,162,095 RGD:6480464
G Top2a DNA topoisomerase II alpha JBrowse link 10 86,901,467 86,930,947 RGD:6480464
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19741
    role 19688
      application 19339
        pesticide 16132
          nematicide 3300
            antinematodal drug 450
              fenbendazole 37
                hydroxyfenbendazole 0
                oxfendazole 19
Path 2
Term Annotations click to browse term
  CHEBI ontology 19741
    subatomic particle 19737
      composite particle 19737
        hadron 19737
          baryon 19737
            nucleon 19737
              atomic nucleus 19737
                atom 19737
                  main group element atom 19622
                    p-block element atom 19622
                      carbon group element atom 19515
                        carbon atom 19508
                          organic molecular entity 19508
                            organic group 18423
                              organic divalent group 18414
                                organodiyl group 18414
                                  carbonyl group 18301
                                    carbonyl compound 18301
                                      carboxylic ester 13967
                                        carbamate ester 7335
                                          fenbendazole 37
                                            hydroxyfenbendazole 0
                                            oxfendazole 19
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.