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Accession:CHEBI:77095 term browser browse the term
Definition:A member of the class of mebendazole in which the benzoyl group is replaced by a p-fluorobenzoyl group. A broad-spectrum anthelmintic, it is used, particularly in veterinary medicine, for the treatment of nematodal infections.
Synonyms:exact_synonym: methyl [5-(4-fluorobenzoyl)-1H-benzimidazol-2-yl]carbamate
 related_synonym: (5-(4-fluorobenzoyl)-1H-benzimidazole-2-yl)carbamic acid methyl ester;   Formula=C16H12FN3O3;   InChI=1S/C16H12FN3O3/c1-23-16(22)20-15-18-12-7-4-10(8-13(12)19-15)14(21)9-2-5-11(17)6-3-9/h2-8H,1H3,(H2,18,19,20,22);   InChIKey=CPEUVMUXAHMANV-UHFFFAOYSA-N;   Methyl N-(5-(p-fluorobenzoyl)-2-benzimidazolyl)carbamate;   R 17,889;   R 17899;   SMILES=COC(=O)Nc1nc2cc(ccc2[nH]1)C(=O)c1ccc(F)cc1;   flubendazol;   flubendazolum;   methyl 5-(p-fluorobenzoyl)-2-benzimidazolecarbamate
 xref: CAS:31430-15-6 "ChemIDplus";   Drug_Central:1186 "DrugCentral";   KEGG:D04200;   LINCS:LSM-5916
 xref_mesh: MESH:C018945
 xref: PMID:20348394 "Europe PMC";   PMID:20444026 "Europe PMC";   PMID:21609260 "Europe PMC";   PMID:22640491 "Europe PMC";   PMID:22717022 "Europe PMC";   PMID:23075539 "Europe PMC";   PMID:23287076 "Europe PMC";   PMID:23884106 "Europe PMC";   PMID:24297155 "Europe PMC";   PMID:3810656 "Europe PMC";   PMID:538808 "Europe PMC";   PMID:6126101 "Europe PMC";   PMID:7101714 "Europe PMC";   PMID:7212160 "Europe PMC";   Patent:DE2029637;   Patent:US3657267;   Reaxys:763480 "Reaxys";   Wikipedia:Flubendazole

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flubendazole term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arhgef2 Rho/Rac guanine nucleotide exchange factor 2 JBrowse link 2 187,964,100 188,022,847 RGD:6480464
G Cdh1 cadherin 1 JBrowse link 19 38,768,467 38,838,395 RGD:6480464
G Cdh2 cadherin 2 JBrowse link 18 8,146,971 8,366,037 RGD:6480464
G Ptk2 protein tyrosine kinase 2 JBrowse link 7 114,436,419 114,611,317 RGD:6480464
G Rac1 Rac family small GTPase 1 JBrowse link 12 13,090,316 13,111,841 RGD:6480464
G Rhoa ras homolog family member A JBrowse link 8 117,082,440 117,116,244 RGD:6480464
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:6480464

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Term Annotations click to browse term
  CHEBI ontology 19741
    role 19688
      biological role 19686
        aetiopathogenetic role 18793
          teratogenic agent 15860
            flubendazole 7
Path 2
Term Annotations click to browse term
  CHEBI ontology 19741
    subatomic particle 19737
      composite particle 19737
        hadron 19737
          baryon 19737
            nucleon 19737
              atomic nucleus 19737
                atom 19737
                  main group element atom 19622
                    p-block element atom 19622
                      carbon group element atom 19515
                        carbon atom 19508
                          organic molecular entity 19508
                            organic group 18423
                              organic divalent group 18414
                                organodiyl group 18414
                                  carbonyl group 18301
                                    carbonyl compound 18301
                                      carboxylic ester 13967
                                        carbamate ester 7335
                                          flubendazole 7
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.