Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:sinapic acid
go back to main search page
Accession:CHEBI:77131 term browser browse the term
Definition:A monohydroxycinnamic acid that is cinnamic acid in which the phenyl hydrogens at positions 3, 4, and 5 are replaced by methoxy, hydroxy, and methoxy groups, respectively.
Synonyms:exact_synonym: 3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoic acid
 related_synonym: 3,5-dimethoxy-4-hydroxycinnamic acid;   Formula=C11H12O5;   InChI=1S/C11H12O5/c1-15-8-5-7(3-4-10(12)13)6-9(16-2)11(8)14/h3-6,14H,1-2H3,(H,12,13);   InChIKey=PCMORTLOPMLEFB-UHFFFAOYSA-N;   SMILES=COc1cc(C=CC(O)=O)cc(OC)c1O
 xref: CAS:530-59-6;   DrugBank:DB08587;   KEGG:C00482
 xref_mesh: MESH:C073734
 xref: Wikipedia:Sinapinic_acid


show annotations for term's descendants           Sort by:
 
sinapic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G G6pd glucose-6-phosphate dehydrogenase decreases activity ISO sinapinic acid results in decreased activity of G6PD protein CTD PMID:25130191 NCBI chr  X:156,274,800...156,293,935
Ensembl chr  X:156,274,800...156,293,926
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO sinapinic acid inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA] CTD PMID:18841975 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Mb myoglobin multiple interactions EXP sinapinic acid inhibits the reaction [Isoproterenol results in increased expression of MB protein] CTD PMID:32627257 NCBI chr 7:118,101,633...118,108,864
Ensembl chr 7:118,101,634...118,108,864
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO sinapinic acid inhibits the reaction [Lipopolysaccharides affects the localization of NFKB1 protein] CTD PMID:18841975 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO sinapinic acid inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased degradation of NFKBIA protein] CTD PMID:18841975 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO sinapinic acid inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; sinapinic acid inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] CTD PMID:18841975 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Ogdh oxoglutarate dehydrogenase multiple interactions EXP sinapinic acid inhibits the reaction [Isoproterenol results in decreased activity of OGDH protein] CTD PMID:32627257 NCBI chr14:86,414,924...86,481,903
Ensembl chr14:86,414,949...86,613,327
JBrowse link
G Pgd phosphogluconate dehydrogenase decreases activity ISO sinapinic acid results in decreased activity of PGD protein CTD PMID:25130191 NCBI chr 5:165,966,128...165,982,327 JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO sinapinic acid inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; sinapinic acid inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein] CTD PMID:18841975 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO sinapinic acid inhibits the reaction [Lipopolysaccharides affects the localization of RELA protein] CTD PMID:18841975 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO sinapinic acid inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA] CTD PMID:18841975 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19816
    chemical entity 19816
      molecular entity 19814
        polyatomic entity 19727
          heteroatomic molecular entity 19653
            hydroxides 19107
              organic hydroxy compound 18661
                phenols 18145
                  sinapic acid 11
                    cis-sinapic acid 0
                    trans-sinapic acid + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19816
    subatomic particle 19814
      composite particle 19814
        hadron 19814
          baryon 19814
            nucleon 19814
              atomic nucleus 19814
                atom 19814
                  main group element atom 19702
                    p-block element atom 19702
                      carbon group element atom 19608
                        carbon atom 19597
                          organic molecular entity 19597
                            organic group 18537
                              organic divalent group 18530
                                organodiyl group 18530
                                  carbonyl group 18436
                                    carbonyl compound 18436
                                      carboxylic acid 18114
                                        monocarboxylic acid 17476
                                          alpha,beta-unsaturated monocarboxylic acid 11372
                                            cinnamic acids 2376
                                              hydroxycinnamic acid 1253
                                                monohydroxycinnamic acid 919
                                                  sinapic acid 11
                                                    cis-sinapic acid 0
                                                    trans-sinapic acid + 0
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.